Thalassemia Quiz

In alpha thalassemia, the defect primarily affects the synthesis of:

• Alpha globin chains

• Beta globin chains

• Gamma globin chains

• Delta globin chains

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

The production of abnormal or insufficient globin chains in thalassemia results in:

• Decreased oxygen affinity of hemoglobin

• Increased red blood cell size

• Enhanced erythrocyte survival

• Impaired hemolysis

Tags

NGSS.HS-LS3-2

Thalassemia is characterized by:

• Increased red blood cell production

• Abnormal hemoglobin synthesis

• Elevated levels of iron in the blood

• Excessive destruction of red blood cells

Tags

NGSS.HS-LS3-2

Which of the following is a common clinical feature of thalassemia major?

• Splenomegaly

• Hypertension

• Hypercholesterolemia

• Thrombocytopenia

Beta thalassemia results from:

• Deficient synthesis of alpha globin chains

• Excessive production of gamma globin chains

• Deficient synthesis of beta globin chains

• Abnormal synthesis of delta globin chains

Tags

NGSS.HS-LS3-2

Which of the following accurately describes the pathophysiology of thalassemia intermedia?

• Mild anemia requiring occasional transfusions

• Severe anemia with symptoms appearing in infancy

• Moderate anemia with symptoms appearing in adulthood

• Absence of anemia due to compensatory mechanisms

Tags

NGSS.HS-LS3-2

The severity of thalassemia is influenced by:

• Number of white blood cells

• Presence of coagulation factors

• Type and extent of globin chain deficiency

• Platelet count

Tags

NGSS.HS-LS3-2

Which of the following is a treatment modality for managing iron overload in thalassemia patients?

• Iron supplementation

• Chelation therapy

• Blood transfusions

• Erythropoietin injections

In thalassemia, excess iron accumulation primarily occurs due to:

• Increased dietary iron intake

• Decreased iron absorption

• Repeated blood transfusions

• Enhanced iron excretion

What is the primary goal of treatment in thalassemia major?

• Stimulate erythropoiesis

• Correct coagulation abnormalities

• Manage iron overload

• Improve platelet function