Haemostasis 3 Quiz

What is the function of the fibrinolytic system?

• Localizing thrombus to the site of injury

• Increasing blood viscosity

• Producing fibrin

• Activating platelets

Which of the following is a plasminogen activator?

• Thrombomodulin

• Factor IX

• Tissue plasminogen activator (t-PA)

• Factor VIII

What is the main inhibitor of thrombin?

• Antithrombin

• Protein C

• Tissue Factor Pathway Inhibitor (TFPI)

• Factor V

Which of the following is an inhibitor of fibrinolysis?

• Tissue plasminogen activator (t-PA)

• Activated protein C

• Thrombomodulin

• Factor VII

What is the function of activated protein C?

• Inhibits thrombin

• Binds to FXa

• Degrades factor IXa

• Inactivates factor V & VIII

What is the main inhibitor of thrombin?

• Thrombomodulin

• Antithrombin

• Tissue Factor Pathway Inhibitor (TFPI)

• Protein C

Which of the following is a function of the fibrinolytic system?

• Localizing thrombus to the site of injury

• Activating platelets

• Preventing the formation of clots

• Promoting the formation of clots

What is the role of tissue plasminogen activator (t-PA) in the fibrinolytic system?

• It is released from endothelial cells and binds to fibrin once the vessel is damaged

• It inactivates plasminogen activator inhibitor (PAI)

• It stimulates activated protein C to destroy plasma inhibitors of t-PA

• It is a synthetic enzyme used in clinical practices

Which of the following inhibits fibrinolysis by activating thrombin-activated fibrinolysis inhibitor (TAFI)?

• Thrombin

• Plasminogen activator inhibitor (PAI)

• Circulating plasmin

• Activated protein C

What is the purpose of the coagulation cascade inhibitors?

• To activate the fibrinolytic system

• To influence the size and stability of clots

• To prevent the production of fibrin

• To promote the formation of clots