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Immunogenetics Quiz

Authored by Thathapudi Jesse Joel

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Immunogenetics Quiz
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10 questions

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1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Who introduced the concept of genetic recombination mechanisms of V, D, and J genes in the loci encoding the immunoglobulin (IG) chains?

Van Dongen JJ

Anton W. Langerak

Erasmus MC

Susumu Tonegawa

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the term used to refer to the enormous repertoire diversity of B and T lymphocytes?

Immunogenetics

Immunome

Precision Immunology

Hematology-Immunology

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which technology allowed for a more high-resolution immune repertoire analysis via massively parallel sequencing?

Next-generation sequencing

Southern blot analysis

Fragment analysis

Sanger sequencing

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the spectrum of IG/TR immune repertoire diversity that can be disclosed using high-throughput sequencing technologies?

Monoclonal

Clonal

Oligoclonal

Polyclonal

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What phase of immune repertoire analysis involves the choice of sample type, nucleic acid type, and IG/TR targets?

Immuno-informatics phase

Analytical phase

Post-analytical phase

Pre-analytical phase

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which aspect of immunogenetics allows for extraction of IG/TR repertoire sequences from -omics data sets?

Southern blot analysis

Sanger sequencing

RNA sequencing

Fragment analysis

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What do immunogenetic profiles constitute in the hematology-immunology domain?

Viral infections

Physiological and pathophysiological signatures of cell populations

Genetic mutations

Immune disorders

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