lecture 11

What type of reactions are Bypass #2 and #3 described as?

• Endergonic

• Exergonic

• Isotonic

• Hypotonic

What is the enzyme involved in Bypass #2?

• Glucose-6-phosphatase

• Fructose bisphosphatase

• Hexokinase

• Phosphofructokinase

What is the product of Bypass #3?

• Fructose-6-Phosphate

• Glucose

• ATP

• Pyruvate

In Bypass #3, what is the product formed along with glucose?

• ATP

• ADP

• Pi (inorganic phosphate)

• NADH

What is the major point of regulation for glycolysis versus gluconeogenesis?

• Phosphofructokinase (PFK-1)/Fructose-1,6-bisphosphatase

• Hexokinase

• Pyruvate kinase

• Lactate dehydrogenase

What is the role of Phosphofructokinase (PFK-1) in glucose metabolism?

• It inhibits glycolysis.

• It commits glucose to glycolysis.

• It promotes gluconeogenesis.

• It converts glucose to fructose.

Which condition favors gluconeogenesis ?

• High AMP

• Low ATP

• High ATP

• Low citrate

What happens when ATP levels are high in the cell?

• Energy is needed; favor glycolysis

• Energy is not needed; favor gluconeogenesis

• Energy is needed; favor gluconeogenesis

• Energy is not needed; favor glycolysis

What effect does high AMP have on cellular metabolism?

• Need energy; favor gluconeogenesis

• Need energy; favor glycolysis

• Don’t need energy; favor gluconeogenesis

• Don’t need energy; favor glycolysis

select types of site found on Phosphofructokinase (PFK1)

• subunit 1

• ATP

• ADP

• Allosteric regulators