HEMA - LAB

Vascular damage uncovers the subendothelial collagen as well as von Willebrand Factor (vWF) contained in endothelial cells' Weibel-Palade bodies.

The local neurohumoral responses as well as endothelial factors which include endothelin drive the blood vessels to narrow and limit the flow of blood straight away following damage.

The property by which platelets bind nonplatelet surfaces such as subendothelial collagen.

Is characterized by changes in form, the release of granules (which carry ADP, serotonin, and other substances), and the exposing of binding sites for other platelets.

Is the property by which platelets bind to one another.

Aided through a number of receptors on the platelet surface, particularly glycoprotein IIb/IIIa, which attaches fibrinogen and vWF, permitting platelets to cling together.

Occurs as more platelets aggregate, closing the injured location and temporarily stopping subsequent bleeding.

This constriction, which is brought about through the contraction of smooth muscle cells in the vessel wall, serves to reduce blood loss.

An important endothelial cell-produced anticoagulant is

Controls activation of the tissue factor pathway.