Cell Biology Quiz: Cell Cycle and DNA Mutations

Which of the following is NOT a type of point mutation?

• Deletion

• Substitution

• Insertion

• Duplication

Which type of mutation involves the substitution of a purine base for a pyrimidine base?

• Transition mutation

• Transversion mutation

• Silent mutation

• Frameshift mutation

What type of agent is a carcinogen?

• Causes developmental abnormalities

• Causes cancer

• Causes chromosome fragmentation

• Causes mutations

Which of the following is a physical mutagen?

• N-methyl-N-nitrosourea

• 5-bromouracil

• UV rays

• Ethylmethane sulfonate

What is a common result of UV radiation on DNA?

• Dimerization of adjacent pyrimidine bases

• Deletion of entire genes

• Insertion of nucleotides

• Base substitution

Which type of mutation is characterized by the removal of an amino group from a base?

• Intercalation

• Base pairing

• Deamination

• Alkylation

What is the effect of alkylating agents on DNA?

• They act as base analogs

• They induce heat-induced mutations

• They can block replication by forming crosslinks

• They cause dimerization of bases

Which disease is caused by point mutations?

• Cystic fibrosis

  and

  Sickle cell anemia

• Cystic fibrosis

• Down syndrome

• Sickle cell anemia