Mmg second

Which of the following are the criteria to activate lac operon?

• Presence of lactose

• Absence of lactose

• Glucose not enough

• Enough glucose

What is incorrect about the control of transcription?

• Regulator proteins and small effector molecule can affect the initiation of transcription

• higher the rate of activity from co-repressor, causes higher the rate of gene expression

• higher the rate of activity from inducer, causes higher the rate of gene expression

• Lower the rate of inhibitor, lower the rate of gene expression

What is incorrect about translational regulation

• Genetic regulation of translation is usually aim at preventing the initiation of translation.

• Repressor protein bind outside the shine dalgarno sequence to stailise mRNA secondary structure that prevents initiation

• Repressor protein bind to shine dalgarno sequence to translation cannot start

• Occurs via feedback inhibition and covalent modification

What is the primary role of sigma factor in bacterial transcription?

• Termination of transcription

• Recognition and bind to promoter region

• Dna replication

• Ribosome assembly

Which feature of -10 region (pribnow box) makes it crucial for transcription initiation?

• High GC content for stability

• Signals termination of transcription

• AT rich sequence that is easy to unwind

• It is ribosome binding site

How does Rho protein facilitate Rho-dependent termination?

• Binds to ribosome and stops translation

• Binds to rut site and unwinds RNA-DNA hybrid

• Enhances RNA polymerase activity

• Forms hairpin loop in mRNA

Which amino acids are commonly phosphorylated?

• Lysine valine methionine

• Serine threonine tyrosine

• Glutamine proline alanine

• Histidine tryptophan leucine

In cystic fibrosis, where does the misfolded CFTR protein get degraded?

• Golgi

• Endoplasmic Reticulum

• Lysosome

• Ribosome

Which of the following best describes the role of cyclins in cell cycle regulation?

• Degrade damaged DNA

• Acts as enzyme that replicate DNA

• Bind to cyclin-dependent kinases (CDKs) to regulate progression thru cell cycle

• Directly inhibit mitosis

What is the primary function of G1 checkpoint?

• Ensure spindle fibres attach properly

• Check for DNA damage before replication

• Verify completion of DNA replication

• Signal the start of anaphase