Arsenic-Containing Molecules 1

The video provides an extensive study on arsenic-containing compounds, highlighting their extreme toxicity and detrimental effects on cellular processes. It explains arsenic's structure, resonance, and its ability to uncouple glycolysis and inhibit the pyruvate dehydrogenase complex, leading to reduced ATP production and potential cell apoptosis. The video also discusses arsenic's broader biological impacts, including its role in DNA methylation, cell division disruption, and carcinogenic potential.

What is one of the primary toxic effects of arsenic on cells?

• It stabilizes cell membranes.

• It promotes cell growth.

• It induces necrosis and apoptosis.

• It enhances ATP production.

How does arsenate's structure contribute to its solubility in water?

• It has a high molecular weight.

• It forms covalent bonds with water.

• It is non-polar and hydrophobic.

• It has partial charges that make it polar.

What is the geometry of the arsenate molecule?

• Octahedral

• Tetrahedral

• Linear

• Trigonal planar

What is the effect of arsenate on glycolysis?

• It uncouples glycolysis, reducing ATP yield.

• It enhances ATP production.

• It has no effect on glycolysis.

• It increases the rate of glycolysis.

Which enzyme is allosterically inhibited by arsenic compounds, affecting energy production?

• Phosphofructokinase

• Lactate dehydrogenase

• Pyruvate dehydrogenase complex

• Hexokinase

What is a common effect of arsenic on DNA?

• It repairs DNA damage.

• It affects DNA methylation, altering gene expression.

• It stabilizes DNA structure.

• It enhances DNA replication.

Which of the following is NOT a property of arsenic compounds?

• They enhance cellular respiration.

• They cause inflammation.

• They induce oxidative stress.

• They are carcinogenic.

How does arsenic affect nitric oxide synthase?

• It activates the enzyme.

• It enhances the enzyme's activity.

• It inactivates the enzyme.

• It has no effect on the enzyme.

What is a potential consequence of arsenic-induced DNA methylation changes?

• Enhanced DNA repair

• Decreased mutation rates

• Increased DNA stability

• Uncontrolled cell proliferation

What is the primary effect of Arsene on red blood cells?

• It stabilizes hemoglobin.

• It enhances oxygen transport.

• It causes hemolytic anemia.

• It increases red blood cell production.