Duchenne Muscular Dystrophy Overview

The video discusses Duchenne Muscular Dystrophy (DMD), a genetic disorder affecting boys, causing muscle weakness and leading to wheelchair dependency by age 12. It explains the genetic mutation in the dystrophin gene, symptoms, and differences between DMD and Becker's Muscular Dystrophy. Diagnosis involves muscle biopsy and cardiac tests. Treatment focuses on supportive care, exercises, and medications like prednisone to improve muscle strength. The video concludes with case studies highlighting symptoms and diagnostic challenges.

What is the genetic inheritance pattern of Duchenne Muscular Dystrophy?

• X-linked recessive

• X-linked dominant

• Autosomal recessive

• Autosomal dominant

At what age do symptoms of Duchenne Muscular Dystrophy typically begin to appear?

• Around age 10 to 12

• Around age 5 to 6

• Around age 2 to 3

• At birth

What is the role of the dystrophin protein in muscle cells?

• It is involved in muscle contraction.

• It acts as a structural component of the muscle cell membrane.

• It provides energy to muscle cells.

• It helps in the repair of muscle fibers.

Which sign is characteristic of Duchenne Muscular Dystrophy?

• Gower sign

• Babinski sign

• Tinel sign

• Romberg sign

How does Becker Muscular Dystrophy differ from Duchenne Muscular Dystrophy?

• Becker does not affect the heart.

• Becker affects only females.

• Becker is less severe and has a later onset.

• Becker is more severe and has an earlier onset.

What is a common cause of death in patients with Duchenne Muscular Dystrophy?

• Liver failure

• Brain hemorrhage

• Kidney failure

• Respiratory failure

Which diagnostic test is crucial for confirming Duchenne Muscular Dystrophy?

• CT scan

• Blood test

• Muscle biopsy

• MRI scan

What is the primary goal of treatment for Duchenne Muscular Dystrophy?

• To enhance cognitive function

• To prevent genetic transmission

• To manage symptoms and improve quality of life

• To cure the disease

Which medication is commonly used to improve muscle strength in DMD patients?

• Metformin

• Prednisone

• Ibuprofen

• Aspirin

What is a potential side effect of long-term steroid use in DMD treatment?

• Improved vision

• Weight gain and cushingoid appearance

• Increased appetite

• Hair loss