Histamine Synthesis and Metabolism Pathway

The video tutorial explains histamine's synthesis and metabolism. Histamine, a biogenic amine, acts as a signaling molecule and neurotransmitter. It is derived from histidine and produced by various cells like mast cells and basophils. The enzyme histidine decarboxylase, with pyridoxal phosphate as a coenzyme, converts histidine to histamine. Histamine is metabolized through pathways involving enzymes like histamine N-methyltransferase and diamine oxidase, leading to excretion in urine. The tutorial concludes with a call to action for viewers to engage with the content.

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