WorksheetsCancer and Genetics
Total questions: 35
Worksheet time: 24mins
Name
Class
Date
1.
Cancer creates abnormal cells by disrupting
a)
the cell cycle
b)
red blood cell formation
c)
DNA replication
d)
ATP synthesis
2.
An abnormal mass of cancer cells is called a
a)
tumor
b)
cyst
c)
lesion
d)
polyp
3.
Metastasis is
a)
the spread of cancer from one part of the body to another.
b)
the growth of tumors in the lungs
c)
cancer of the blood cells
d)
cancer that is found in connective tissues
4.
What kind of a gene is p53?
a)
Proto-Oncogene
b)
Oncogene
c)
Tumor Suppressor Gene
d)
Proto-Tumor Suppressor Gene
5.
What type(s) of cancer(s) is associated with the BRCA1 gene?
a)
Breast Cancer Only
b)
Ovarian Cancer Only
c)
Breast and Ovarian Cancer
d)
Leukemia
6.
Damage to which type of genes is the most common cause of cancer?
a)
Oncogenes
b)
Tumor Suppressor Genes
c)
Proto-Oncogenes
d)
Apoptosis-Inducing Genes
7.
Restriction Enzymes . . .
a)
cut DNA at precise locations
b)
help bacteria to pick up DNA
c)
move DNA through a gel
d)
copy DNA
8.
What charge is DNA?
a)
positive
b)
negative
c)
neutral
9.
During gel electrophoresis, DNA moves from the ___ end to the ___ end.
a)
positive, negative
b)
negative, positive
10.
In gel electrophoresis, the largest DNA fragment will appear
a)
closest to the starting wells
b)
farthest from the starting wells
c)
three quarters away from the starting wells
d)
it depends on how many fragments there are
11.
Which types of molecules travel the farthest in gel electrophoresis?
a)
smallest ones
b)
longest ones
c)
widest ones
d)
most annoying ones
12.
Which of the following is needed to make an electrophoresis gel?
a)
Acid
b)
Microwave
c)
Beaker
d)
Stirring Rod
13.
What molecule other than DNA can be separated based on its size?
a)
Carbohydrate
b)
Lipid
c)
Protein
d)
Water
14.
Based on these results whose blood was found in the blood stain at the crime scene?
a)
Bob
b)
Sue
c)
John
d)
Lisa
15.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His
16.
What is occurring in this picture?
a)
Translation
b)
DNA Replication
c)
Polymerase is unzipping the DNA
d)
Transcription
17.
What mutation has occurred here?
T-G-A-C-C-A
T-G-A-G-C-A
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift
18.
Which phase of which process does this picture show?
a)
Transcription
b)
Translation
c)
Replication
19.
Which is the mRNA molecule that would be transcribed from this DNA template:
TGGCAAGTACGT
TGGCAAGTACGT
a)
ACCGTTCATGCA
b)
UGGCAAGUACGU
c)
UCCGUUCUUGCU
d)
ACCGUUCAUGCA
20.
ATTTGAGCC - Original
ATTGAGCC - Mutated
The example above is an example of a
ATTGAGCC - Mutated
The example above is an example of a
a)
Insertion- Frameshift
b)
Deletion- Substitution
c)
Deletion -Frameshift
d)
All of the above
21.
Why are insertion and deletion mutations so harmful?
a)
They change all of the codons from the mutation on down the line, which changes the amino acid sequence
b)
They insert things that an organism doesn't need.
c)
They often delete things that organisms need.
d)
Insertion and deletions are not any more harmful than substitution mutations.
22.
Why is the order of amino acids so important?
a)
The order of amino acids dictates the function of the protein and what shape the protein will fold into.
b)
It is not important. The protein folding chamber will force the protein to fold into the correct shape.
c)
The order of the amino acids tells the cell what DNA to make.
d)
It is not important that is why most mutatiosn are silent.
23.
Which of the following represents a gene?
a)
p53
b)
ATCGAATTA
c)
chromosome 17
d)
X
24.
Which of these important events in cancer history came first?
a)
The BRCA 1 gene was cloned
b)
Gardisil and Cervarix 2 vaccines are placed on the market to prevent HPV
c)
Gel electrophoresis was developed to sequence DNA
d)
FDA approved 3 dimensional mammography for diagnosing breast cancer
25.
Which of these important events in cancer history happened most recently?
a)
The number of human chromosomes was determined to be 46
b)
Gardisil and Cervarix 2 vaccines are placed on the market to prevent HPV
c)
A mutation on a single gene in 5-10% of women is linked to breast cancer and called the Breast cancer 1 gene
d)
Cancer was linked to damage at cell cycle checkpoints
26.
Which of the following is the job of a genetic counselor?
a)
Perform genetic testing.
b)
Extract DNA from patients
c)
Explore a patient's family history
d)
Perform gene therapy
27.
Which of the following would you expect a genetic counselor to say?
a)
Everyone should have genetic testing done
b)
Genetic testing is free
c)
People under the age of 25 should not be genetically tested
d)
Cancer is not linked to genetics
28.
What does the histology grade tell you on a pathology report?
a)
the size of the tumor
b)
the shape and look of the cancer cells compared to normal cells
c)
how fast the cancer is spreading
d)
when the cancer reached the lymph nodes
29.
Terry's cancer has spread from her breast to her lung...what stage of cancer is she in?
a)
Stage 0
b)
Stage 1
c)
Stage 2
d)
Stage 3
e)
Stage 4
30.
Which stage of cancer has 3 substages?
a)
Stage 1
b)
Stage 2
c)
Stage 3
d)
Stage 4
e)
Stage 0
31.
Which diagnostic tool uses x-rays to detect microcalcifications as a sign of cancer?
a)
mammogram
b)
MRI
c)
Biopsy
d)
Ultrasound
32.
Which diagnostic tools may be used together to detect cancer?
a)
mammogram and MRI
b)
MRI and Biopsy
c)
Biopsy and Ultrasound
d)
Ultrasound and mammogram
33.
If a cancer patient tests positive for PR and ER receptors they may be a candidate for which type of treatment?
a)
chemotherapy
b)
surgery
c)
biological therapy
d)
hormone therapy
34.
If a cancer patient tests positive for HER2 receptors they may be a candidate for which type of treatment?
a)
chemotherapy
b)
surgery
c)
biological therapy
d)
hormone therapy
35.
Which cancer treatment often results in the loss of hair and vomitting?
a)
chemotherapy
b)
surgery
c)
biological therapy
d)
hormone therapy
100 %
