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Long Exam 2 in Genetics

Total questions: 45

Worksheet time: 14mins

Name
Class
Date
1.

Which sequence of events occurs in the process of making genetically modified bacteria?

a)

Extraction of required gene → Insertion of plasmid into bacterial cells → Growth of transformed bacterial cells

b)

Growth of transformed bacterial cells → Insertion of plasmid into bacterial cells → Extraction of required gene

c)

Insertion of plasmid into bacterial cells → Growth of transformed bacterial cells → Extraction of required gene

d)

Growth of transformed bacterial cells → Extraction of required gene → Insertion of plasmid into bacterial cells

2.

What is transferred from one organism to another in the process of genetic engineering?

a)

bases

b)

enzymes

c)

DNA

d)

RNA

3.

What is the name of the structure found in bacterial cells into which genes can be inserted?

a)

Protein

b)

Plasmid

c)

Nucleus

d)

Ribosome

4.

What is the biological role of restriction enzymes?

a)

Aid in recombinant DNA research

b)

Make bacteria resistant to antibiotics

c)

Degrade foreign DNA that enters a bacterium

d)

Cleave DNA at or near specific sequence of bases

5.

In the laboratory, how will recombinant plasmids are commonly introduced into bacterial cells?

a)

Microinjection

b)

Infection with a bacteriophage that carries the plasmid

c)

Mixing plasmids with an extract of broken cells

d)

Heat shock of the cells incubated with plasmid DNA

6.

What is the DNA molecule produced by combining DNA from different sources?

a)

GMO

b)

Mutant

c)

Recombinant DNA

d)

Complementary DNA

7.

Which of the following steps is NOT essential in producing recombinant DNA?

a)

Use a restriction enzyme to cut DNA

b)

Cut out a piece of DNA from a DNA molecule

c)

Read the sequences of bases in a piece of DNA

d)

Insert a piece of DNA from one organism into the DNA of another organism

8.

To produce a bacterium that make insulin, which of the following steps did scientists have to take first?

a)

Insert the human insulin gene into a plasmid

b)

Extract the insulin from the bacterial culture

c)

Use a restriction enzyme to cut out the insulin gene from human DNA

d)

Transform bacteria with the recombinant plasmid

9.

DNA from a human has been inserted into bacterial plasmid and reinserted back into the bacterium. The bacterium now contains both human DNA and bacterial DNA. The bacterium is now considered a _________.

a)

Mutant

b)

Clone

c)

PCR Product

d)

Transgenic Organism

10.

Which of the following is NOT an argument in favor of GMOs?

a)

Reduced biodiversity

b)

Disease-resistant Crops

c)

Food with Extra Nutrients

d)

Controlled Production of Insulin

11.

What is most likely an application of using DNA recombinant technology in helping environmental scientists would be?

a)

Use PCR to analyze DNA at a crime scene

b)

Create a tobacco plant that glows in the dark

c)

Clone the gene for human growth hormone to treat pituitary dwarfism

d)

Make transgenic bacteria that can be used to clean up oil spills more quickly than do the natural bacteria

12.

Which of the following do NOT belongs to the group?

a)

Glowing Rabbits

b)

Naked Chicken

c)

Enviro Pigs

d)

Golden Rice

13.

Fill in the blanks. Golden Rice is a genetically modified crop plant where the incorporated genes from _____ and ______ are meant for biosynthesis of ______.

a)

Daffodil, E. coli, Vitamin B

b)

Chrysanthemum, Salmonella, beta-carotene

c)

Chrysanthemum, Salmonella, Vitamin C

d)

Daffodil, E. coli, Beta-carotene

14.

Click all the organisms that are selectively bred.

a)

Belgian Blue

b)

Flavr Savr

c)

Champion Race Horses

d)

Bt Corn

e)

Naked Chicken

15.

What is this type of selective breeding where two individuals with unlikely characteristics are crossed to produce the organism with desired traits?

a)

Artificial Selection

b)

Hybridization

c)

Cloning

d)

Gene Splicing

16.

What was the first animal successfully cloned?

a)

Dog

b)

Goat

c)

Rat

d)

Sheep

17.

What is the gene involved that triggers the naked chicken to be featherless?

a)

Featherless gene

b)

Scaleless gene

c)

GFP gene

d)

PSY gene

18.

Super Salmon is a transgenic organism that grows super fast as compared a non-transgenic salmon. Where is the gene involved to this fast-growing salmon came from?

a)

A rapidly replicating bacteria

b)

Fish growing in cold season

c)

Fish growing in warm season

d)

A jellyfish from Pacific Ocean

19.

Enviro-pigs are genetically-engineered to produce the enzyme phytase in its salivary glands to enable more effective digestion of phytate, coming from the _______ found in pig feed ingredients like corn and soybeans.

a)

Potassium

b)

Calcium

c)

Selenium

d)

Phosphorus

20.

To make the recombinant plasmid permeable to DNA molecules, which of the chemicals is added?

a)

MgCl2

b)

CaCl2

c)

NaCl

d)

HCl

21.

In which stage of genetic engineering a probe is used?

a)

Cleaving DNA using restriction enzymes

b)

Recombining DNA

c)

Transformation of bacteria

d)

Isolation through screening

22.

A repeating DNA sequence at the end of chromosomes that prevents them from losing base pair sequences at their ends and from fusing together is called:

a)

tRNA

b)

Telomere

c)

5' cap

d)

Poly-A tail

23.

The enzyme that creates a short RNA oligonucleotide at initiation sites where replication is to be carried out is called:

a)

Primase

b)

DNA Ligase

c)

DNA Gyrase

d)

Exonuclease

e)

Single Strand Binding Proteins

24.

Because DNA polymerase III can only act from 5' to 3', continuous strand growth can be achieved only along one of the template strands (Leading strand) and strand growth along the other strand must occur discontinuously resulting in the production of a series of short sections of new DNA called:

a)

RNA Primers

b)

Lagging Strand

c)

Okazaki Fragments

d)

Discontinuing Strands

25.

What is the major difference between the DNA replication in prokaryotes and eukaryotes?

a)

replication is conservative in prokaryotes

b)

DNA amylase performs the function of DNA helicase in prokaryotes

c)

prokaryotes do not use Topoisomerase in the replication process

d)

there is only one replication origin in prokaryotes.

26.

The enzyme responsible for initiating the unwinding of double-stranded DNA (eliminating supercoiling) by nicking a single strand of the DNA molecule is:

a)

Ligase

b)

Helicase

c)

Topoisomerase

d)

Transferase

e)

Polymerase

27.

A series of 100 to 200 Adenine ribonucleotides that is added to the 3' end of the transcribed RNA molecule (pre-mRNA) that helps in the transportation of mRNA out of the nucleus is called:

a)

Trailer

b)

5' cap

c)

Poly-A Tail

d)

3' Tail

28.

Sections of DNA within a gene that do not encode part of the protein that the gene produces are called :

a)

Introns

b)

Exons

c)

Transposons

d)

Interferons

29.

The enzyme that forms a peptide bond between adjacent amino acids in the ribosome during translation is called :

a)

Exonuclease

b)

Peptidyl Transferase

c)

Peptidase

d)

Proteinase

30.

Semi-conservative replication in DNA was first demonstrated in:

a)

Streptococcus pnemoniae

b)

Salmonella typhimurium

c)

Escherichia coli

d)

Drosophila melanogaster

31.

When DNA replication starts?

a)

The phosphodiester bonds between the adjacent nucleotides break

b)

The bonds between nitrogen base and deoxyribose sugar break

c)

The leading strand produces Okazaki fragments

d)

Hydrogen bonds between two nucleotides break

32.

Which of the following enzyme is responsible for making a DNA copy from RNA?

a)

Reverse transcriptase

b)

DNA polymerase

c)

RNA Polymerase

d)

Spliceosome

33.

What amino acid sequence will be generated based on the following mRNA codon sequence? 5' AUG-UCU-UCG-UUA-UCC-UUG 3'

a)

MET-ARG-GLU-ARG-GLU-ARG

b)

MET-GLU-ARG-ARG-GLN-LEU

c)

MET-SER-LEU-SER-LEU-SER

d)

MET-SER-SER-LEU-SER-LEU

34.

A peptide has the sequence NH2-PHE-PRO-LYS-GLY-PHE-PRO-COOH. Which of the following sequences in the coding strand of the DNA could code for this peptide?

a)

5' GGG-AAA-TTT-AAA-CCC-ACT-GGG

b)

5' TTT-CCC-AAA-GGG-TTT-CCC

c)

3' AUG-AAA-GGG-TTT-CCC-AAA-GGG

d)

3' UUU-CCC-AAA-GGG-UUU-CCC

35.

Some events that take place during the synthesis of a specific protein are listed below.

A. DNA polymerase produces complementary nucleotides.

B. SSBP prevent the strands from bonding.

C. Two identical copies of the DNA are produced.

D. Helicase unwinds the two DNA strands.

E. Primase creates a primer to mark the start of production of bases.

The correct order of these events is:

a)

DEACB

b)

DAECB

c)

DBEAC

d)

DBAEC

36.

A biochemist isolates, purifies, and combines in a test tube a variety of molecules needed for DNA replication. When she adds some DNA to the mixture, replication occurs, but each DNA molecule consists of a normal strand paired with numerous segments of DNA a few hundred nucleotides long. What has she probably left out of the mixture?

a)

Helicase

b)

Transferase

c)

Polymerase

d)

Primase

37.

DNA that results from replication consists of ___?

a)

one molecule with two new strands and one molecule with the two original strands

b)

two molecules that each contain one new strand and one original strand

c)

two molecules composed of new strands

d)

two molecules composed of old strands

38.

If this strand, A A T G C C A G T, is replicated, which of the following is the complementary strand that is produced?

a)

T C G T C C G T C

b)

A G C A G G C A G

c)

A G C A C C C A G

d)

T T A C G G T C A

39.

All the nucleotides contain each of the following EXCEPT

a)

Pentose Sugar

b)

Nitrogen Base

c)

Amino Group

d)

Hydrogren Bonds

e)

Phosphates

40.

The main function of the DNA is

a)

basic component of proteins

b)

carrier of hereditary information

c)

carrier of amino acids in protein synthesis

d)

principal energy molecules in cellular processes

41.

It is a technique where in bad genes are replaced with healthy genes, what is this technique called?

a)

Cloning

b)

Gene Replacement

c)

Gene Switch

d)

Gene Theraphy

42.

This method is used to fire DNA coated pellets on plant tissues.

a)

Heat Shock

b)

Electroporation

c)

Biolistics

d)

PCR

43.

Which of the following statements is true regarding the discovery of the double helix?

a)

Rosalind Franklin’s x-ray crystallography provided Watson and Crick with important data that helped determine the structure of DNA.

b)

It was discovered that double-stranded DNA is a parallel molecule.

c)

James Watson, Francis Crick, Maurice Wilkins, and Rosalind Franklin were awarded the Nobel Prize in Medicine for their discovery of the double helix.

d)

The experiments that led to the discovery of the double helix ultimately disproved Chargaff's rules regarding nitrogenous bases.

44.

True or False. Brocolli. Cabbages. and Kale are GMOs.

a)

TRUE

b)

FALSE

45.

True or False. GMOs are transgenic organisms

a)

TRUE

b)

FALSE