WorksheetsAP2 Endo
Total questions: 83
Worksheet time: 42mins
Which mediator does not act as both a neurotransmitter and hormone?
Norepinephrine
Epinephrine
Oxytocin
Thyroxine
Describe a type of mediator that is released throughout the brain and expressed by neurons.
Neurotransmitter
Hormone
Melatonin
Serotonin
Hormone receptors are...
Cellular proteins located both on the cell surface and inside the cell.
Lipopolysaccharides located both on the cell surface and inside the cell.
Cellular Phospholipids located both on the cell surface and inside the cell.
Lipopolysaccharides proteins located on the cell surface.
Receptor down regulation occurs when....
too much hormone is present.
not enough hormone present
wrong hormone present
Receptor-up regulation occurs when...
Too much hormone present
Not enough hormone present
right hormone present
What type of local hormone acts on the same cell that secreted it?
Paracrines
Epicrines
Autocrines
Americans
What type of local hormone acts on neighboring cells
Paracrine
Autocrine
American
Holocrine
Which hormones act more quickly?
Local
Circulating
Amino Acid hormones in the amine group are made of a modification of single ...
Tryptophan or tyrosine
Glutamine or glutamate
Alanine or glycine
None of these are true
Amino Acid Hormones are generally...
Water soluble
Lipid soluble
Amphipathic
Bound to a protein carrier in blood
Water soluble hormones bind to receptors
Inside the cell
On the cell surface
On free cholesterol molecules
within the diaphragm
Which list contains only amino acid hormones?
T3, T4, Histamine, Calcitonin
T3, T4, Histamine, Calcitriol
Parathyroid hormone, Leptin, Cortisone, HGH
Aldosterone, Estrogen, DHEA-sulfate, Cortisone
Which binds to a receptor inside the cell?
Calcitonin
Calcitriol
Parathyroid hormone
Thyroxin
Which of the following is binds to the thyroid hormones in blood?
TBG
TGB
DIT
MIT
Which of the following is binds to the thyroid hormones in blood?
TBG
TGB
DIT
MIT
Which of the following suffixes do not belong to the steroid hormones
-One
-gen
-ol
—nin
Most steroid hormones are transported through the blood to target cells via...
proteins made in the liver
Proteins made in the thalamus
they done need carriers
They only act locally
an example of a hormone used in a positive feedback system would be...
Oxytocin
Prolactin
Insulin
Thyroxin
Which two effectors receive their input most directly from the hypothalamus?
adenohypophysis/pars nervosa
neurohypophysis/pars nervosa
adenohypophysis/ pars tuberalis
Zona glomerulosa/ pars intermedia
What makes up the majority of the weight of the hypophysis?
Pars distalis
Pars nervosa
Infundibular stalk
Hypothalamus
5 tropic hormones are released from the adenohypophysis. Which one acts on almost all tissues in the body rather than just another endocrine gland?
HGH
MSH
LH/FSH
TSH
ACTH
Somatotrophs produce...
HGH
MSH
LH/FSH
TSH
ACTH
Thyrotrophs produce...
HGH
MSH
LH/FSH
TSH
ACTH
Lactotrophs produce...
PRL
MSH
LH/FSH
TSH
ACTH
FSH is produced by
Somatotrophs
thyrotrophs
Gonadotrophs
Lactotrophs
Corticotrophs
LH is produced by
Somatotrophs
thyrotrophs
Gonadotrophs
Lactotrophs
Corticotrophs
ACTH is produced by
Somatotrophs
thyrotrophs
Gonadotrophs
Lactotrophs
Corticotrophs
MSH is produced by
Somatotrophs
thyrotrophs
Gonadotrophs
Lactotrophs
Corticotrophs
another name for HGH is
somatotropin
somatostatin
somatotroph
another name for GHIH is
somatotropin
somatostatin
somatotroph
Dopamine inhibits
MSH
PIH
PRH
ACTH
What is the most abundant hormone secreted by the pars distalis usually secreted in bursts every few hours.
somatotropin
Dopamine
Prolactin
thyrotropin
Somatotropin production increases...
First thing in the morning
as it starts to get dark outside
during REM sleep
during deep sleep
when Insulin-like growth factor present
IGF’s are also known as...
Somatostatins
Somatotrophs
Somatomedins
Somatotaxins
Oddly, Insulin-like Growth Factors are very similar to glucagon in their actions. What is one aspect of IGF’s that is not mentioned as a role of Glucagon?
Increases protein synthesis
Enhances Lipolysis
Increases Glycogenolysis
Produced when hypoglycemic
Increases blood glucose
Production of this would be inhibited by hypoglycemia
GHIH
GHRH
Glucagon
A hormone secreted by stomach right before meals
Ghrelin
Estrogen
Testosterone
Insulin
Glucagon
What is a factor that inhibits hGH secretion
somatotropin and somatostatin
Deep sleep
Hypoglycemia
Low BMI
ACTH controls the production of which hormone?
Cortisol from the adrenal cortex
Epinephrine from the adrenal medulla
Norepinephrine from the adrenal medulla
Oxytocin from the hypothalamus
Ejection of milk is caused by...
Oxytocin
Proloactin
FSH/LH
Progesterone
Estrogen
If you have a lot of dopamine, you’re probably...
not producing milk
protecting your cell nucli from Sun rays.
having uterine contractions
releasing IGF’s
Dopamine secretion is lowest when?
just prior to menstruation when levels of estrogen and progesterone are low
During childbirth when prolactin and oxytocin are high
during ovulation when estrogen and progesterone are high
During times of stress when cortisol production is elevated
FSH and LH are stimulated to be produced in the pars distalis when which hormone is released by the hypo thalamus?
GnRh
GHIH
GHRH
Oxytocin
Hormone that stimulates production of follicle and sperm and is inhibited by negative feedback from estrogen and testosterone.
FSH
LH
PRL
PIH
PRH
Hormone that stimulates ovulation, formation of corpus luteum, and therefore secretion of progesterone. Also triggers secretion of estrogen and testosterone.
FSH
LH
PRL
PIH
PRH
PIH inhibits...
Production of MSH in the adenohypophysis
production of MSH in the skin
Production of Prolactin from the neurohypophysis
Production of Prolactin from the hypothalamus
Negative feedback from the Thyroid T3/T4 causes
Changes in production of TRH
Changes in production of ACTH
Decreased T3/T4 production
Decreased TSH production
the posterior pituitary stores and releases which two hormones
ADH, Vasopressin
Vasopressin, Dopamine
Vasopressin, Oxytocin
ADH, Dopamine
Drinking alcohol results in decreased production of ...
Vasopressin resulting in dehydration
Vasopressin resulting in hypotonicity of blood
Oxytocin resulting in headaches and irritability
Oxytocin resulting in hypotonicity of blood
Osmoreceptors are a type of ...
Chemoreceptor
Baroreceptor
What causes inhibition of ADH release due to changes in the blood affecting osmoreceptors in the hypothalamus
Dehydration
Hemorrhage
Diarrhea
Excessive sweating
Blood hypotonicity
Action of ADH on the kidneys causes...
Water reabsorption
Decreased sweating
Arteriolar constriction
Increased sweating
Besides osmoreceptors, Vasopressin secretion can be altered by
Morphine
Tranquilizers
Some anesthetics
Nicotine
All of the above
In the blood, the lady is to T4 as the horse is to ...
TGB
TBG
Tetraiodothyronine
Triiodothyronine
Thyroid hormone synthesis occurs in the thyroid in the presence of...
Thyroxin
TRH
Calcitonin
Thyrotropin
Anything that causes an increase in cellular energy demand causes an _________in thyroid hormone production.
Increase
Decrease
Which of the following would cause a an increase in cellular energy demand?
Cold environment
Hypoglycemia
High altitude
Pregnancy
All of the above
Lobes of the thyroid are connected by the ...
Isthmus
Follicle
Parathyroid
Infundibular stalk
Some people have a third lobe of the thyroid called the...
Pyramidal lobe
Occipital lobe
Thymal lobe
Butterfly lobe
Produces calcitonin
Parafollicular cells
Kidney
Parathyroid Gland
Follicles of the thyroid
Inactive, more abundant, less potent thyroid hormone
T4
T3
Thyroxine
T4/Thyroxine
T3/Thyroxine
Active, less abundant, more potent thyroid hormone
T4
T3
Thyroxine
T4/Thyroxine
T3/Thyroxine
The only endocrine gland that stores its hormones in large quantities - 100 days worth
Thyroid
Parathyroid
Pancreas
Thymus
In the presence of Thyrotropin, Follicular cells pull_________ into the cytosol._________ then ____________ this molecule to an active form,__________ .
Iodide, perioxidase, oxidizes, iodine
Iodine, perioxidase, oxidizes, iodide
Iodide, lysosomes, oxidize, iodine
Iodide, lysosomes, reduce, iodine
TGB is produced in the endoplasmic reticulum, packaged by the golgi apparatus, and released by ________ into the _________
exocytosis, lumen (colloid)
Exocytosis, interstitial fluid
pinocytosis, colloid
Pinocytosis, interstitial fluid
Once TGB and Iodine are in the colloid, they react at what site to form MIT and DIT. What portion of the TGB do Iodines bind to?
Tyrosine
Heavy band
Tryptophan
Light chain
Once monoiodotyrosine’s and diiodotyrosines are formed, they combine to form...
Thyroid hormones
TGB
TBG
Colloid enters the cell via pinocytosis. Before T3/T4 can leave the follicular cell, _________ must digest the ________ allowing the T3/T4 to make its way to the blood.
Lysosomes, TGB
Lysosomes, TBG
Peroxisomes, TGB
Peroxisomes, TBG
If dude is the active form of thyroid hormone, he is ...
Triiodothyronine
T4
Thyroxine
Thyrotropin
Thyroid hormones increase BMR by...
Stimulates synthesis of Sodium/Potassium Pumps
Producing ATP
Allowing calcium into the cell
Activating calcium pumps in the sarcoplasmic reticulum.
T3/T4 can enhance the actions of some catecholamines such as Epinephrine and Norepinephrine via...
Up regulation of beta adrenergic receptors
Down regulation of beta adrenergic receptors
Up regulation of cholinergic receptors
Down regulation of cholinergic receptors
Production of calcitonin by parafollicular cells occurs when...
Blood calcium is high
Blood calcium is low
PIH is present
PIH is absent
Calcitonin...
Inhibits osteoclasts and resorption
Inhibits osteoblasts and deposition
Increases calcium absorption in the intestines
Increases calcium reabsorption in the nephron
Parathyroid gland creates a hormone that ...
Inhibits osteoclasts and resorption
Inhibits osteoblasts and deposition
decreases calcium absorption in the intestines
decreases calcium reabsorption in the nephron
Principal cells (Chief cells) are the functional unit of the...
Parathyroid gland
Thyroid gland
Thymus
Pancreas
Produces mineralcorticoids (aldosterone)
Zona Glomerulus
Zona Fasciculata
Zona Reticularis
Medulla
Produces glucocorticoids (cortisol)
Zona Glomerulus
Zona Fasciculata
Zona Reticularis
Medulla
Produces androgens (dihydrotestosterone)
Zona Glomerulus
Zona Fasciculata
Zona Reticularis
Medulla
Glucocorticoids are effective in regaining homeostasis when
Stressor is removed promptly
Stressor remains for significant amount of time
Which is the most potent androgen?
DHEA (Dehydroepiandosterone)
Androstenedione
Dihydrotestosterone
Testosterone
Functional unit of the adrenal medulla
Chromaffin cells supplied by splanchnic nerves
Chromafin cells supplied by post ganglionic, sympathetic nerves
Principle cells supplied by splanchnic nerves
Principle cells supplied by post ganglionic, sympathetic nerves
Chromaffin cells secrete catecholamines that intensify sympathetic responses throughout the body
True
False
The function of the pancreas is primarily through the secretion of
Endocrine hormones
Exocrine enzymes
