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WorksheetsProtein Translation
Total questions: 50
Worksheet time: 1hrs 1mins
Name
Class
Date
1.
Translation takes place in the
a)
ribosome
b)
chloroplast
c)
nucleus
d)
mitochondria
2.
Brings the amino acids to the ribosome
a)
mRNA
b)
tRNA
c)
rRNA
d)
DNA
3.
What would be the tRNA anticodon for the mRNA codon CAG?
a)
GTC
b)
GUC
c)
CUG
d)
CAG
4.
What is the term for a three-nucleotide sequence that codes for an amino acid?
a)
base
b)
codon
c)
amine
d)
serine
5.
Which phrase best describes translation?
a)
converts mRNA into a polypeptide
b)
catalyzes bonds between amino acids
c)
produces RNA from DNA molecules
d)
recycles tRNA molecules for reuse
6.
What type of bonds are forming during translation?
a)
Peptide bonds
b)
Hydrogen bonds
c)
Acid bonds
7.
EXTRA AWESOME QUESTION: Which types of cells can begin the process of translation even before the mRNA has been completely transcribed?
a)
Eukaryotes
b)
Prokaryotes
c)
Both Prokaryotes and Eukaryotes can
d)
No cells can can do this
8.
How many amino acids are coded for by this sequence of nucleotides:
ATG GGA ACT CCA
ATG GGA ACT CCA
a)
4
b)
2
c)
6
d)
12
9.
Which phase of which process does this picture show?
a)
Transcription
b)
Translation
c)
Replication
10.
What would happen if we did not have start codons?
a)
Polypeptide chains would continue to grow
b)
Amino acids would bind to tRNA
c)
Protein synthesis wouldn't occur
d)
mRNA would form a double strand
11.
Which of the following occurs first in translation?
a)
The small ribosomal subunit binds to mRNA
b)
The large ribosomal subunit binds to mRNA
c)
tRNA binds to the mRNA
d)
A peptide bond forms between amino acids
12.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His
13.
. What are the building blocks of proteins called?
a)
nucleotides
b)
proteins
c)
amino acids
d)
carbohydrates
14.
Using the codon identify the amino acid sequence:
AUG-CCA-GUA-GGG-UAA
AUG-CCA-GUA-GGG-UAA
a)
MET-HIS-ALA-GLY-STOP
b)
MET-PRO-GLY-VAL-STOP
c)
MET-PRO-VAL-GLY-STOP
d)
MET-THR-SER-ASP-STOP
15.
What structure in a cell is the site for making proteins?
a)
ribosomes
b)
mitochondria
c)
lysosome
d)
Golgi body
16.
What is this a picture of?
a)
mRNA
b)
tRNA
c)
rRNA
d)
pRNA
17.
Which amino acid is made from the RNA codon UUA?
a)
Phenylalanine
b)
Leucine
c)
Serine
d)
Tyrosine
18.
What is the relationship between a protein, the cell, and DNA?
a)
DNA is produced by protein which is produced in the cell
b)
Protein is composed of DNA which is produced in the cell
c)
DNA makes RNA which produces protein in the cell
d)
A cell is composed of DNA and protein
19.
Process in which amino acids are assembled into proteins at the ribosome?
a)
Translation
b)
Transcription
c)
Meiosis
d)
Replication
20.
If the mRNA sequence is AGA UUU CGA GCC,
what is the complementary tRNA anticodons?
what is the complementary tRNA anticodons?
a)
AGA TTT CGA GCC
b)
UCU AAA GCU CGG
c)
TCT AAA GCT CGG
d)
UCU AAA CGA GGG
21.
What is the correct sequence of protein synthesis?
A. tRNA brings amino acids to the ribosome
B. DNA molecules serve as the templates for mRNA.
C. mRNA molecules move to ribosomes.
D. Polypeptides are formed on ribosomes.
a)
A-B-C-D
b)
B-C-A-D
c)
C-B-A-D
d)
D-B-A-C
22.
Overall, protein synthesis consists of these steps
a)
DNA synthesis, RNA synthesis and transcription
b)
transcription and translation
c)
DNA synthesis, transcription and translation
23.
In RNA, Uracil pairs with ______.
a)
cytosine
b)
adenine
c)
guanine
d)
thymine
24.
The process to go from DNA to mRNA is _______
a)
translation
b)
transcription
c)
replication
25.
The process to go from mRNA to a protein is called ____
a)
transcription
b)
rRNA
c)
replication
d)
translation
26.
What is the function of the poly-A tail in mRNA?
a)
to add modified guanin to the 3' end of the mRNA
b)
to indicate the site of translational termination
c)
to code for the binding of RNA polymerase to the DNA
d)
to help protect the mRNA from degradation by hydrolytic enzymes
27.
What must happen to a newly made polypeptide before it can be secreted from a cell?
a)
it must be translated by a ribosome that remains free of attachment to the ER
b)
its signal sequence must target it to the ER, after which it goes to the Golgi
c)
Its signal sequence must be cleaved off
d)
Its signal sequence must target it to the plasma membrane
28.
Which is the best description of a gene?
a)
a DNA sequence that is expressed to form a functional product; either RNA or polypeptide
b)
a DNA subunit that codes for a single complete protein
c)
a DNA-RNA sequence combination that results in an enzymatic product
d)
a descrete unit of hereditary information that consists of a sequence of amino acids
29.
A possible sequence of nucleotides in the template strand of DNA that would code for the polypeptide sequence phe-leu-ile-val would be?
a)
5'-TTG-CTG-CAG-TAG-3'
b)
3'-AAC-GAC-GUC-AUA-5'
c)
3'-AAA-AAT-ATA-ACA-5'
d)
3'-AAA-GAA-TAA-CAA-5'
30.
A tRNA (#1) attached to the amino acid lysine enters the ribosome. The lysine binds to the growing polypeptide on the other tRNA (#2) already in the ribosome. Where does tRNA (#2 move to next?
a)
A site
b)
P site
c)
E site
d)
exit tunnel
31.
What is a peptide bond?
a)
Bond that holds two amino acids together.
b)
A bond that holds hydrogen and oxygen molecules together.
c)
A bond that holds the phosphate group of one nucleotide and a sugar of a neighboring nucleotide.
d)
A bond that is formed by the sharing of electrons.
32.
The diagram shows a bond forming between two amino acids. What is the name of this reaction?
a)
Dehydration Synthesis
b)
Hydrolysis
c)
Pepysis
d)
Oxidation
33.
Each amino acid is different from the other due to....
a)
The R group
b)
The amino group
c)
The carboxyl group
d)
The central carbon
34.
Where does transcription occur in eukaryotic cells?
a)
Nucleus
b)
Ribosome
c)
Cytoplasm
d)
Rough E.R.
35.
A certain gene codes for a polypeptide that is 120 amino acids long. Approximately how many nucleotides long is the mRNA that codes for this polypeptide likely to be?
a)
360
b)
480
c)
40
d)
30
36.
This is the triplet of bases on the end of a tRNA molecule
a)
Anticodon
b)
Codon
c)
Protein
37.
A frameshift mutation could result from
a)
a base insertion only.
b)
a base deletion only.
c)
a base substitution only.
d)
either an insertion or a deletion of a base.
38.
Original: ATC CAT
Mutation: ATC GCAT
What mutation occurred?
Mutation: ATC GCAT
What mutation occurred?
a)
deletion
b)
insertion
c)
silent
d)
transverse
39.
What is an exon?
a)
section of mRNA that codes for protein
b)
section of mRNA that does not code for protein
c)
section of tRNA that codes for protein
d)
section of rRNA that codes for protein
40.
Where is the TATA box found?
a)
in the promoter sequence of prokaryotes
b)
in the terminator sequence of prokaryotes
c)
in the promoter sequence of eukaryotes
d)
in the terminator sequence of eukaryotes
41.
A mRNA sequence consist of 171 nucleotides. How many amino acids make up the protein this sequence will code for?
a)
57
b)
56
c)
58
d)
513
42.
This is one job proteins do NOT have in the body
a)
storing genetic information
b)
structure
c)
speed up chemical reactions
d)
transport things through cell membrane
43.
Which of the following events in translation is the first to occur in eukaryotes?
a)
elongation of the polypeptide
b)
base pairing of activated methionine-tRNA to AUG of the messenger RNA
c)
binding of the larger ribosomal subunit to smaller ribosomal subunits
d)
the small subunit of the ribosome recognizing and attaching to the 5'cap
44.
Which ribosome part contains a tRNA after it has dropped off its amino acid & is about to exit?
a)
A site
b)
P site
c)
E site
d)
B site
45.
What happens in RNA processing and where does it occur?
a)
5' cap and 3' poly A tail added, in nucleus
b)
3' cap and 5' poly A tail added, in cytoplasm
c)
introns cut out and exons reattached, nucleus
d)
introns cut out and exons reattached, cytoplasm
46.
Flexible base pairing between some tRNAs & codons where 3rd base can mismatch?
a)
wobble
b)
gobble
c)
autonomy
d)
mismatch
47.
Place the order of events for
creating a protein in order (1- 6)
____mRNA attaches to rRNA
____codons are continuously read by tRNA
____tRNA reaches a stop codon
____ tRNA connects second amino acid by peptide bond to Methionine
____Polypeptide chain is created
____ mRNA’s start codon AUG is translated by tRNA’s anticodon (Methionine)
a)
1,5,4,3,6,2
b)
2,4,5,3,6,1
c)
1,2,3,4,5,6
d)
1,4,5,3,6,2
48.
The reaction used to digest and break the bond in red is:
a)
Hydrolysis
b)
Dehydration Synthesis
c)
Oxidation
d)
Single Displacement
49.
The two types of folding in the secondary structure are.....
a)
alpha-helix & beta-pleated sheets
b)
polypeptide & nucleotide
c)
globular & fibrous
50.
The difference between tertiary and quartenary structure is:
a)
Tertiary structure has double bond whereas quartenary structure does not have double bond
b)
Tertiary structure consists of one polypeptide chain whereas quartenary structure consists of more than one polypeptide chains
c)
Tertiary structure is fibrous whereas quartenary structure is globular
d)
Tertiary structure is water-soluble whereas quartenary structure is lipid soluble
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