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WorksheetsBiochemistry
Total questions: 103
Worksheet time: 1hrs 20mins
What is the positive visible result for Liebermann – Burchard test?
yellow crystal
white amorphous precipitate
black precipitate
bluish-green color
The enzymes for glycolysis are found in the
mitochondrion
ribosome
cytosol
nucleus
This is differentiating test for aldose and ketose sugars?
Seliwanoff's Test
Barfoed Test
Mucic Acid Test
Any of the above
This is also known as Embden- Mayeroff pathway?
glycolysis
glycogenesis
Gluconeogenesis
glycogenolysis
The nonsugar portion of glycosides is known as (Multiple answers)
Aglycone
Genin
Glycone
Glycine
What type of glycosidic bond joins the dimer of glucose to form maltose?
alpha 1, 4
beta 1, 4
alpha 1, 2
beta 1, 2
Glucose and galactose differ only in the configuration of their -OH group at C4, thus they are called
diastereomers
enantiomers
anomers
epimers
This DNA duplex has a special left handed- helical structure.
A-DNA
B-DNA
Z-DNA
F-DNA
Which of the following amino acids has an imino group?
F
Y
V
P
The fibrous proteins is the most abundant single proteins in vertebrates.
Keratin
Collagen
Elastin
Fibronectin
Which of the following is soluble in water and salt solutions, and has no distinctive amino acids?
Protamine
Globulin
Albumin
Histones
What enzyme is responsible for converting phenylalanine to tyrosine
Phenylalanine hydroxylase
Phenylalanine dehydrogenase
Phenylalanine ligase
Phenylalanine kinase
Which of the following enzyme/s may be used to diagnose myocardial infarction? (Multiple Answers)
Gamma glutamyl transpeptidase
AST/SGOT
Creatinine phosphokinase
Lactate dehydrogenase
Acute pancreatitis may be diagnose using which serum enzymes? (Multiple answers)
Acid phosphatase
Alkaline phosphatase
Lipase
Amylase
Which of the following enzymes adds an inorganic phosphate to break a bond?
Kinase
Phosphorylase
Phosphatase
Ligase
What is the deficiency state of folic acid?
Aplastic anemia
Pernicious anemia
Megaloblastic anemia
Macrocytic anemia
This class of immunoglobulin is produced during the early response to invading organisms. It has a relatively large size that restricts its transport in the bloodstream.
IgG
IgM
IgE
IgD
This term refers to an intact with a bound co-factor?
Holoenzyme
Apoenzyme
Zymogen
Prosthetic group
Which of the following test is specific for amino acids and free amino group
Biuret test
Hopkins Cole test
Ninhydrin
Xanthoproteic test
Xanthprotheic test is a test for?
Free Amino groups
Arg
Cys
Tyr
This test is used to identify the presence of peptide linkage?
Ninhydrin
Sakaguchi
Hopkins Cole
Biuret
Hopkins Cole is used to identify which of the following amino acids?
T
W
L
K
Specific test for Arg
Biuret test
Basic Lead Acetate Test
Ninhydrin
Sakaguchi
This is also known as protein calorie malnutrition. It is a state resulting from the chronic deficiency of calories , which can occur even in the presence of adequate intake of protein.
Marasmus
Obesity
Hemochromatosis
Kwashiorkor
The digestion of protein begins in the
Mouth
Stomach
Small intestine
Pancreas
Pepsinogen is an example of
Apoenzyme
Holoenzyme
Cofactor
Zymogen
Racemase and mutase are examples of what type of enzymes?
Lyases
Isomerases
Oxidoreductase
Ligase
Which of the following enzymes is an example of hydrolases?
esterase
racemase
racemase
decarboxylase
Maltose, a disaccharide is composed of
glucose + galactose
glucose + fructose
glucose + glucose
glucose + mannose
Which of the following carbohydrates contains the most number of carbon atoms?
sedoheptulose
sialic acid
ribose
glycerose
Which of the following present a cyclic sugar nature?
Fischer projection
Boat conformation
Chair projection
Haworth projection
The glycosidic formed in glycosides is an example of
ester bond
ether bond
ketone bond
Noncovalent bond
Which pancreatic cell type of its responsible for secreting Insulin hormone?
A cell or α
B cell or β
D cell or δ
F cell or γ
The cell markers, which serve as basis for the ABO blood types, are classified as what type of biopolymers?
proteins
lipids
carbohydrates
nucleic acids
Which of the following is the reason why blood type AB is considered as universal recipient?
It is the most common among the ABO blood types
Blood type AB has neither A nor B substances
blood type AB has neither anti- A nor anti- B antibodies
all of the above
Which of the following is / are examples of glycosaminoglycans?
hyaluronic acids
mucopolysaccharides
chondroitin sulfate
all of the above
Raffinose, a trisaccharide also known as (Multiple answers)
melitose
melitriose
melezitose
melititrose
α-napthol reaction is also known as
Molisch test
Ninhydrin test
Phenylhydrazine test
Fehlings test
The inhibition in noncompetitive reaction _______.
competes with the active site of the enzyme
binds simultaneously with substrate other than the active site
increases the rate of reaction
It is a precursor of vit. A
β-carotene
retinol
retinal
Tretinoin
It is the organelle which serves as the site of the electron transport chain.
mitochondria
ribosome
nucleus
lysosome
The active proteolytic enzyme in gastric juice is:
Chymotrypsin
catalase
maltase
Trypsin
The enzyme conformation adapts to the incoming substrate in
Lock and Key theory
Induced Fit Model
competitive inhibition
Enzyme activity
The process of converting glucose into glycogen is called
gluconeogenesis
glycogenesis
glycolysis
glycogenolysis
A hormone which stimulates glycogenesis:
insulin
glucagon
epinephrine
vasopressin
A synthetic DNA is called
replicated DNA
plasmid
gene
recombinant DNA
The transfer of genetic information from DNA by the formation of mRNA
transcription
translation
transamination
replication
The ff. are phospholipids, except:
plasmalogen
lecithin
cephalin
choline
The central compound found in the structure of sphingolipids:
glycerol
sphingosine
ceramide
phosphocholine
The ff. are glycolipids except:
globosides
phosphatides
gangliosides
cerebrosides
The reagent present is Molisch test which is responsible for the dehydration reaction:
sodium carbonate
magnesium stearate
sulfuric acid
NaOH
ID test to detect the presence of glycogen:
phloroglucinol
molisch
iodine
Seliwanoff
Important structural material found in the exoskeletons of many lower animals:
chnondroitin
heparin
hyaluronic acid
chitin
Type of RNA which serves as template for the amino acid sequence being synthesized:
mRNA
tRNA
rRNA
none of the above
Anaerobic glycolysis occurs in the
nucleus
mitochondria
cytoplasm
lysosomes
Osazone test is also known as:
Nylander's
Kowarsky test
Trommer's
Folin's test
Body functions of lipids:
transformation into proteins and carbohydrates
catabolism to provide body with heat and energy
insulation and paddings for organs
all of the above
In man, the principal end product of protein metabolism is:
uric acid
lactic acid
pyruvic acid
urea
Condition wherein acetone accumulates in the blood:
ketosuria
ketonemia
ketosis
ketonuria
Glutamine is a _____ amino acid:
neutral
basic
acidic
racemin
Most amino acids do not absorb visible light and thus are colorless. However, there are some that can absorb light. Which of the following groups of amino acids contribute to the ability of most proteins to absorb high wavelength (250-290nm) UV light?
Alanine, Valine, Leucine
Arginine, Lysine and Histidine
Trytophan, Tyrosine and Phenylalanine
Glutamate, and Aspartate
Serine, Cysteine, and Threonine
Which of the following pairs of amino acid with the indicated side-chain is correct?
Cysteine-Sulfhydryl Group
Serine-Guanido Group
Valine-Methyl Group
Methionine-Hydroxymethyl Group
Trytophan-Phenol Group
What are the components of endogenous thymidine?
Methylated Deoxyribose and Uracil
Ribose, Thymine and Phosphate
Ribose and Thymine
Deoxyribose, Thymine and Phosphate
Deoxyribose and Thymine
Which amino acid is antagonized by drugs of abuse such as ketamine and phencyclidine and is implicated schizophrenia?
Glycine
Glutamate
Aspartate
Tyrosine
Trypttophan
A 57-year-old man with a long history of alcohol abuse comes to the emergency room with symptoms of confusion and hepatomegaly on examination. The patient also has a flapping tremor at the wrist (asterixis). He is diagnosed with hepatic encephalopathy, which can be partially treated with a diet of branched-chain amino acids. Which of the following sets amino acids would you suggest?
Tryptophan, Phenylalanine, Tyrosine
Methionine, Proline, Cysteine
Aspartate, Glutamine, Asparagine
Alanine, Glycine
Valine, Leucine, Isoleucine
A man diagnosed of Hartnup disease wherein his urinalysis results showed significant increase in neutral amino acids. Which of the following amino acids would have been found in his urine sample?
Histidine
Glutamate
Arginine
Lysine
Phenylalanine
An organelle is the portion of a cell enclosed by a membrane. Based on this, which of the following is not strictly an organelle?
Mitochondrion
Endoplasmic Reticulum
Lysosome
None of the above
Ribosome
Which of the following vitamins may cause CNS disturbances, liver, and skin damage when taken in excess?
A
D
B3
E
B6
Among the major forms of purines found in the DNA, which does not possess an oxo/carbonyl group on the ring?
Adenine
Uracil
Cytosine
Thymine
Guanine
There are several biochemical catalysts found inside and outside the cell. Biomolecules with catalytic activity include:
Enzymes
Enzymes & DNA
Enzymes & Amino Acids
All of the above
Enzymes and RNA
Carcinoid Syndrome can cause Pellagra. Pellagra causes Hartnup Disease.
Statement 1 is TRUE but Statement 2 is FALSE
Statement 2 is TRUE but Statement 1 is FALSE
Both are TRUE
Both are FALSE
Two sugars that differ only in the configuration of one carbon atom other than the terminal carbon atom and the penultimate carbon are called _____.
Anomers
Erythro isomers
Epimers
Threo Isomers
Enantiomers
Amino sugar found in chondroitin
N-acetylfructosamine
N-acetylmuramic acid
N-acetylglucosamine
N-acetylmannosine
N-acetylgalactosamine
The ff. tests have been conducted to an unknown analyte.
Benedict test: (-)
Bial's Test: (-)
Seliwanoff's test: (-)
Lugol's Test: (+)
What is the identity of the analyte?
Ribulose
Ribose
Fructose
Starch
It is the dietary precursor for arachidonic acid.
Oleic acid
Linolenic acid
Cervonic acid
Timnodonic acid
Linoleic acid
In the double stranded DNA, the strand which is transcribed during nucleic acid synthesis is known as ____.
Template strand
Transcribing strand
Replicating strand
Synthetic strand
Coding strand
Amylose differs from amylopectin in that amylose contains α-1,4 linkages while amylopectin contains _____ linkage/s
I. α-(1→2) II. α-(1→4) III. α-(1→6)
I, II & III
II only
I & II
III only
II & III
Phosphatidylcholine is also known as
Lecithin
Cardiolipin
Cephalin
Sphingomyelin
Plasmalogen
Fructose intolerance can lead to
Diarrhea
Constipation
Flatulence
GIT spasms
Hypoglycemia
Docosahexanoic acid found in fish oil preparations such Omacor® is commonly known as?
Palmitoleic acid
Linolenic acid
Timnodonic Acid
Cervonic acid
Linoleic Acid
DNA differs from RNA in that the -OH in C2 of the monosaccharide found in the RNA is replaced by:
Amino group
Hydrogen atom
Nitrogenous base
Carbonyl carbon
Carboxyl carbon
Which of the ff is not a form of DNA within cells
A-DNA
D-DNA
B-DNA
F-DNA
Z-DNA
What is the central nucleus to all sterols?
Cyclopentanephenanthrene
Cyclopentanoperhydrophenanthrene
Cyclopentanoperhydrophenantrene
Steroidal Ring
Cyclopentanophenanthrene
Eicosanoid mediator of bronchoconstriction and airway hyperactivity.
Prostaglandin
Thromboxane
Arachidonic acid
Leukotriene
Prostacyclin
Secondary messengers that are biosynthesized by action of phospholipase C include diacylglycerol and:
Inositol-4,5-bisphosphate
Inositol-1,4,5,6-tetraphosphate
Inositol-1,4,5-trisphosphate
Inositol monophosphate
Inositol-5-phosphate
It is the basic unit glycolipids
Glycerol
Fatty acids
Sphingosine
Phosphatidate
Ceramide
Which of the ff statement/s regarding the Central Dogma of Molecular Biology is/are true?
I. DNA replication occurs in a semi-conservative manner
II. The amino acid sequence of proteins is directly dependent on the nucleotide sequence of the DNA.
III. Reverse transcription is impossible.
I,II,III
I & III
I & II
I only
II & III
Which of the ff is used for determination or testing for the presence of reducing sugars & monosaccharides?
I. Nylander's Test
II. Tauber's Test
III. Barfoed's Test
IV. Seliwanoff's Test
I & III
II & III
I & II
II, III & IV
II & IV
What monosaccharide readily forms osazones?
Galactose
Mannose
Fructose
Ribose
Glucose
In mRNA processing, the 5' end is attached with what nucelotide that serves as a "cap" to render it stable against 5' exonucleases and for it to be recognized by the translation machinery of the cell?
7-methyladenosine triphosphate
1-methylguanosine triphosphate
7-methylguanosine triphosphate
3-methylguanosine triphosphate
7-methylinosine triphosphate
Complementary base pairs in the DNA double helix are bonded by:
H-bond
van der Waals forces
Ester bond
Glycosidic bond
Dipole-dipole forces
Which of the ff statement/s is/are true about uricase?
I. Converts uric acid to H2O-soluble allantoin.
II. It is found only in higher primates.
III. rDNA derived uricases are now being employed for the management of gouty arthritis.
I only
I, II & III
II only
III only
I & II
Which of the ff are isosteric to other amino acids?
H & K
N & D
N & Q
D & N
Which of the ff amino acids are uncharged and polar?
I. H II. N III. S IV. D
I & II
II & III
I & III
II & IV
I & IV
Amino acid that gives a positive result for Sakaguchi reaction
Gelatin
Tyrosine
Arginine
Tryptophan
Alanine
A nucleic acid is made up of
Sugar, Nucleoside and a Base
Proteins, Sugar and Amino acid
Nitrogenous, Amino acid and Sugar
Nitrogenous Base, Phosphate, and Sugar
Phosphate, Proteins, Nitrogenous Base
In the pineal gland, serotonin is converted to melatonin by
I. N-actylation II. N-methylation
III. Oxidation IV. O-methylation
I & II
II & IV
III & IV
I & IV
I & III
Which of the ff antibodies is capable of opsonization?
IgA
IgG
IgD
IgM
IgE
Which of the ff statements is/are true regarding the secondary structure of nucleic acids?
I. Guanine forms base pairs with cytosine via 2 hydrogen bonds.
II. The B form of the DNA is the most common in biological systems.
III. The breaking of H-bonds caused by high temperature is called melting.
I, II & III
I & III
I & II
II only
II & III
Which of the ff is a homotrisaccharide?
Raffinose
Gentianose
Melitose
Maltotriose
Melitriose
What stabilizes the primary structure of proteins?
Salt bridges
Peptide bonds
Hydrophobic Bonds
Hydrophobic interactions
Disulfide Bonds
Which of the ff is not a method of determining primary protein structure?
Mass spectroscopy
Genomics
Edman Reaction
Phenylisothiocyanate Degradation
Polyacrylamide Gel Electrophoresis
The ff is incorrect about protein structure determination except:
NMR is the primary means of determining protein structure.
Large & very complex proteins can only be analyzed by NMR.
Proteins are difficult to crystallize, a disadvantage of X-ray crystallography.
An advantage to the use of x-ray crystallography is that proteins analyzed are in their natural state.
None of the above
