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GIT, Hepatobiliary system & pancreas

Total questions: 75

Worksheet time: 38mins

Name
Class
Date
1.

Balloon cells are found in:

a)

Hairy leukoplakia

b)

Squamous cell carcinoma

c)

Acute hepatitis

d)

Warthin tumor

2.

Which of the following is not a risk factor for squamous cell carcinoma?

a)

Smoking

b)

Alcohol

c)

HPV

d)

Oral contraceptives

3.

Rete pegs are swollen and voluminous in:

a)

Pleomorphic adenoma

b)

Leukoplakia

c)

Ackerman tumor

d)

Acinic cell carcinoma

4.

Pick out the wrong statement about pleomorphic adenoma

a)

Most common benign tumor of salivary gland

b)

Exclusively seen in parotid

c)

Pseudopodia are seen

d)

Unencapsulated and well circumscribed

5.

Pick the correct statement about warthin tumor

a)

Cystic spaces lined by single layer of cuboidal cells

b)

Most common in females

c)

Never involves facial nerve

d)

Not associated with smoking

6.

Ameloblastoma pattern showing squamous metaplasia

a)

Follicular pattern

b)

Acanthomatous pattern

c)

Basal cell pattern

d)

Plexiform pattern

7.

Most common tumor of salivary gland in children

a)

Warthin tumor

b)

Adenoid cystic carcinoma

c)

Mucoepidermoid carcinoma

d)

Acinic cell tumor

8.

Cribriform pattern and swiss cheese appearance are associated with

a)

Warthin tumor

b)

Ackerman tumor

c)

Adenoid cystic carcinoma

d)

Mucoepidermoid carcinoma

9.

Which of th following is not a cause of hematemesis?

a)

Esophageal varices

b)

Mallory Weiss syndrome

c)

Plummer Vinson syndrome

d)

Reflex esophagitis

10.

Barrett Esophagus:

a)

Columnar cells with goblet cells

b)

Squamous cells with goblet cells

c)

Columnar cells with squamous cells

d)

Columnar metaplasia

11.

Risk factor for both squamous as well as adenocarcinoma esophagus

a)

Barrett esophagus

b)

Tobacco

c)

Scleroderma

d)

HPV

12.

The type of ulcers that occur due to intracranial disease

a)

Cushing ulcer

b)

Curling ulcer

c)

Stress ulcer

d)

Peptic ulcer

13.

Not true about H.pylori

a)

Invasive

b)

Humans are the only host

c)

Increased risk of MALToma

d)

Diff-Quik stain can be used

14.

Which of the following is not an askanazy zone?

a)

Necrotic zone

b)

Granulation tissue zone

c)

Deep exudative zone

d)

Cicatrization zone

15.

Sites of peptic ulcer are:

a)

Stomach

b)

Jejunum

c)

Meckel's diverticulum

d)

Colon

16.

Not seen in Zollinger-Ellison syndrome:

a)

Peptic ulcers

b)

Malabsorption

c)

Gastrinoma

d)

Constipation

17.

Which of the following virus is related with gastric carcinoma?

a)

HPV

b)

HBV

c)

EBV

d)

HIV

18.

Not seen in linitis plastica:

a)

Desmoplasia

b)

Loss of E-cadherin

c)

Signet ring cells

d)

Absence of mucin

19.

Sister Mary Joseph nodule :

a)

Periumbilical veins

b)

Most common from carcinoma colon

c)

Subcutaneous

d)

Evidence of desmoplasia

20.

False about gastric carcinoma

a)

Alcohol is a risk factor

b)

Troisier's sign positive

c)

Most common symptom is abdominal pain

d)

CEA is a tumor marker

21.

Carney triad is not associated with:

a)

Paraganglioma

b)

Pulmonary chondroma

c)

Gastric GIST

d)

Cholangiocarcinoma

22.

Most common complication in Meckel's diverticulum

a)

Bleeding

b)

Enterolith

c)

Inflammation

d)

Tumor

23.

Zenker's degeneration is associated with:

a)

Typhoid

b)

Shigella

c)

TB

d)

Amebiasis

24.

All intestinal tuberculosis are caused by:

a)

Mycobacterium tuberculosis

b)

Mycobacterium hominis

c)

Mycobacterium bovis

d)

Mycobacterium avium

25.

Reiter syndrome is seen with:

a)

Typhoid

b)

Shigella

c)

Amebiasis

d)

TB

26.

A person presents with flask shaped ulcers in the colon. True statement is:

a)

It is caused by a gram negative bacteria

b)

It can spread to liver and cause an abcess

c)

It can be diagnosed using widal test

d)

The organism can cause HUS

27.

Select the most aggressive of the following carcinoid tumors

a)

Stomach

b)

Jejunum

c)

Appendix

d)

Esophagus

28.

Gene associated with Crohns disease

a)

CARD15

b)

SPINK1

c)

KIT

d)

KRAS

29.

Major cells involved in pathogenesis of IBD

a)

T cells

b)

B cells

c)

Macrophages

d)

Neutrophils

30.

Not a usual finding in crohn's disease

a)

Skip lesions

b)

Serpentine ulcers

c)

Creeping fat

d)

Basal plasmacytosis

31.

Ulcerative colitis is not associated with:

a)

Pseudopolyps

b)

Cryptitis

c)

Toxic megacolon

d)

String sign

32.

Intussusceptum is:

a)

Entering tube

b)

Middle tube

c)

Sheath

d)

Lesion causing intussusception

33.

Cystically dilated glands are characteristic of :

a)

Juvenile Polyposis Coli syndrome

b)

Puetz - Jeghers Syndrome

c)

Lynch syndrome

d)

Familial Adenomatous Poyposis

34.

Smooth muscle fibres having tree like appearance is characteristic of:

a)

Juvenile polyposis coli syndrome

b)

Peutz Jeghers syndrome

c)

Hyperplastic polyps

d)

Neoplastic polyps

35.

True about adenomas

a)

Tubular adenomas are sessile

b)

Villous papillomas are composed of glands

c)

Sessile serrated adenomas resemble hyperplastic polyps

d)

Sessile serrated adenomas show dysplasia

36.

Turcot syndrome is associated with

a)

FAP

b)

Lynch syndrome

c)

Typhoid

d)

Shigella

37.

Microsatellite instability is seen in

a)

Lynch syndrome

b)

FAP

c)

PJ syndrome

d)

Villous adenomas

38.

Which gene is not involved in adenoma-carcinoma sequence?

a)

APC

b)

SMAD2

c)

KRAS

d)

BRAF

39.

Not associated with carcinoma of left colon

a)

Polypoid mass

b)

Apple core constrictions

c)

Dirty necrosis

d)

Altered bowel habits

40.

Not involved in pathogenesis of acute appendicitis

a)

Ischemia

b)

Infection

c)

Toxins

d)

Hereditary factors

41.

Vitamin seen in hepatic stellate cells:

a)

A

b)

B12

c)

C

d)

E

42.

Pigment granules composed of epinephrine polymers are characteristic of:

a)

Dubin-Johnson syndrome

b)

Rotor syndrome

c)

Crigler-Najjar syndrome type 1

d)

Gilbert syndromm

43.

HBV gene associated with virus infectivity

a)

S

b)

C

c)

P

d)

X

44.

Examination of a person revealed HBSAg and IgG anti-HBcAg in blood. The condition is:

a)

Convalescence

b)

Chronic hepatitis

c)

Acute hepatitis

d)

Immunized person

45.

Pregnant women have a high mortality rate with

a)

HAV

b)

HBV

c)

HEV

d)

HCV

46.

Ground glass hepatocytes are seen in:

a)

Acute hepatitis

b)

HBV carriers

c)

Chronic hepatitis

d)

Hepatoblastoma

47.

Feature not seen with acute hepatitis

a)

Dropout necrosis

b)

Councilman body

c)

Kupffer cell hyperplasia

d)

Bridging fibrosis

48.

Piecemeal necrosis is characteristic of:

a)

Acute hepatitis

b)

Chronic hepatitis

c)

Cirrhosis

d)

Hepatocellular carcinoma

49.

Not involved in pathogenesis of alcoholic liver disease

a)

Proteasome

b)

Methionine metabolism

c)

Neoantigens

d)

CYP3A4

50.

Microvesicular steatosis affects

a)

Acinar zone 1

b)

Acinar zone 2

c)

Acinar zone 3

d)

Whole acinus

51.

Mallory bodies are composed of:

a)

Melanin

b)

Cytokeratin

c)

Lipofuschin

d)

Apoptotic particles

52.

Hobnail appearance of liver is seen in:

a)

Cirrhosis

b)

Hepatitis

c)

Steatosis

d)

Fulminant hepatic failure

53.

Mallory bodies are seen in:

a)

NAFLD

b)

Primary biliary cirrhosis

c)

Hepatocellular carcinoma

d)

Hemochromatosis

54.

NAFLD is not associated with:

a)

Type 1 diabetes

b)

Hypertension

c)

Obesity

d)

Low HDL cholesterol

55.

Which of the following is not associated with portal hypertension?

a)

Spider angiomas

b)

Splenomegaly

c)

Hemorrhoids

d)

Caput medusae

56.

Gamna-Gandy bodies are associated with:

a)

Portal hypertension

b)

Hepatitis

c)

Splenectomy

d)

Carcinoma liver

57.

Finding not seen in hemochromatosis

a)

Reduced TIBC

b)

Macronodular cirrhosis

c)

Skin pigmentation

d)

Raised serum ferritin

58.

Steatosis with acute/chronic hepatitis & mallory bodies are seen in:

a)

HBV infection

b)

HCV infection

c)

Wilson's disease

d)

Postnecrotic cirrhosis

59.

False regarding secondary biliary cirrhosis

a)

Jigsaw puzzle piece nodules

b)

Bile lakes

c)

Affects only small ducts

d)

Proliferation of bile ductules

60.

Characteristic autoantibody in PBC:

a)

PDC-E2

b)

pANCA

c)

LKM-1

d)

APLA

61.

Tombstone scar and onion skin fibrosis is seen in:

a)

Primary biliary cholangitis

b)

Secondary biliary cirrhosis

c)

Primary sclerosing cholangitis

d)

Cholangiocarcinoma

62.

Anchovy sauce pus is associated with:

a)

Liver fluke

b)

Amoeba

c)

E.coli

d)

Klebsiella

63.

False regarding hepatocellular carcinoma

a)

Aflatoxin B1 is a risk factor

b)

KRAS Gene is mutated

c)

Bile production by tumor cells is the hallmark

d)

Clear cell variety is a well differentiated type

64.

Tumor marker for fibrolamellar HCC

a)

Neurotensin

b)

Synaptophysin

c)

AFP

d)

L-fucosidase

65.

PVC exposure leads to

a)

Angiosarcoma

b)

Cholangiocarcinoma

c)

Carcinoma colon

d)

Hepatocellular carcinoma

66.

Klastskin tumors are seen:

a)

Near porta hepatis

b)

Near formation of common bile duct

c)

Near ampulla of vater

d)

Near Hartmann pouch

67.

Central umbilication is characteristic of:

a)

Metastatic tumors

b)

Hepatoblastoma

c)

Fibrolamellar HCC

d)

Cholangiocarcinoma

68.

Not a variety of acute cholecystitis

a)

Emphysematous

b)

Gangrenous

c)

Xanthogranulomatous

d)

Acalculous

69.

Not associated with chronic cholecystitis

a)

Porcelain gall bladder

b)

Rokitansky - Aschoff sinuses

c)

Cholecystitis glandularis

d)

Bacterial inflammation

70.

Which of the following inhibit cholesterol stone formation?

a)

Hypomotility of gall bladder

b)

Calcium salts

c)

Apolipoprotein A1

d)

Mucus

71.

Spiculated (jacklike) gallstones are

a)

Cholesterol stones

b)

Black pigment stones

c)

Brown pigment stones

d)

Oxalate stones

72.

Putty like fluid and enzymatic fat necrosis are associated with the following mutation..

a)

SPINK1

b)

KRAS

c)

SMAD4

d)

PRSS1

73.

Parenchymal fibrosis and acinar atrophy in pancreas are associated with :

a)

Acute pancreatitis

b)

Chronic pancreatitis

c)

Pseudocyst pancreas

d)

Carcinoma pancreas

74.

Pseudocyst pancreas is lined by:

a)

Double layered epithelium

b)

Single layered epithelium

c)

Fibrous connective tissue

d)

Elastic connective tissue

75.

False about pancreatic carcinoma

a)

Earliest gene mutation is KRAS

b)

Show perineural invasion

c)

CA-19-9 is the gold standard tumor marker and also the best diagnostic test

d)

Trosseau's syndrome is seen

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