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L3: Infection and Response

Total questions: 70

Worksheet time: 2hrs 21mins

Name
Class
Date
1.

What does communicable disease mean?

a)

A disease that can be spread from one person to another.

b)

A disease that cannot be treated with antibiotics.

c)

A disease that is not spread from animals to humans.

d)

A disease that is passed on through genes.

2.

What is a pathogen?

a)

A small group of viruses

b)

The name given to colds and flu's

c)

A microorganism that causes disease

3.

The different types of pathogens are _________________ .

a)

germs, bugs, insects, fleas

b)

bacteria, fungi, virus, protists

c)

bacteria, bacterium, virus, virium

d)

vermin, bugs, fungi, protists

4.

Which best compares a virus to a bacterium?

a)

A virus is a large, living particle, and a bacterium is a large, living cell.

b)

A virus is a tiny, nonliving particle, and a bacterium is a large, living cell.

5.

Bacteria and viruses can reproduce quickly inside the body and make people feel ill. Bacteria and viruses make us feel ill because they produce _______________ .

a)

antitoxins

b)

toxins

c)

antibodies

6.
 is a microscopic organism, and is able to multiply only within the living cells of a host.
a)
bacteria
b)
virus
c)
parasite
d)
fungus
7.

Pathogens can be spread by

a)

direct contact

b)

air

c)

water

d)

telepathy

8.

The spread of disease can be prevented by

a)

simple hygiene measure

b)

destroying vectors

c)

isolation of infected individuals

d)

vaccination

9.
Symptoms of this disease include a fever and a red rash. 
a)
Measles
b)
Gonorrhoea
c)
Salmonella
d)
HIV
10.

Which type of pathogen causes Measles?

a)

Bacterium

b)

Fungus

c)

Protist

d)

Virus

11.

How is measles often transmitted?

a)

Through the air

b)

Via dirty water

c)

Via uncooked food

12.
This disease is spread by sexual contact or exchange of body fluids such as blood which occurs when drug users share needles.
a)
Measles
b)
Gonorrhoea
c)
HIV
d)
Salmonella
13.

HIV/AIDS is what type of pathogen?

a)

A virus

b)

A fungus

c)

A bacterium

14.

People can pay for their child to be vaccinated against chickenpox.


The vaccination stimulates the production of antibodies.


Which part of the blood produces antibodies?

a)

White blood cells

b)

Red blood cells

c)

Platelets

d)

Plasma

15.

Chickenpox is a disease. Many children get chickenpox. Most children recover quickly with no serious long term effects. Chickenpox cannot be treated with antibiotics.


What type of pathogen causes chickenpox?

a)

bacteria

b)

virus

16.

A viral disease found in humans?

a)

Rose black spot

b)

Tobacco mosaic virus

c)

AIDS

d)

Malaria

17.

A viral disease found in plants?

a)

Rose black spot

b)

Tobacco mosaic virus

c)

AIDS

d)

Malaria

18.

A bacterial disease spread by contaminated food?

a)

Malaria

b)

Salmonella

c)

Measles

d)

Gonorrhoea

19.

In which foods is Salmonella more likely to be found?

a)

Meat, eggs and poultry

b)

Vegetable and fruit

c)

Seeds and nuts

20.

What is used to treat salmonella?

a)

Antibiotics

b)

Painkillers

c)

Chemotherapy

21.

A woman becomes ill and has the following symptoms:


• pain when urinating

• thick yellow discharge from vagina.


Which communicable disease

does the woman have?

a)

Gonorrhoea

b)

HIV

c)

Measles

d)

Salmonella

22.

Which type of pathogen causes Gonorrhoea?

a)

Bacterium

b)

Fungus

c)

Protist

d)

Virus

23.

Which fungus plant disease is this?

a)

Rose Black Spot

b)

Chlorosis

c)

Tobacco Mosaic Virus

d)

Damping Off

24.

In which way does cold spread?

a)

Drinking contaminated water

b)

Animals that draw blood

c)

Droplets in the air when people cough or sneeze

d)

Eating food that is contaminated

e)

Breathing air polluted with carbon dioxide

25.

Which hair-like structures in the airways prevent the entrance of pathogens to the lungs?

a)

Cilia

b)

Mitochondria

c)

Flagella

d)

Plasmids

26.

Which acid is found in the stomach and helps to kill pathogens that have been ingested?

a)

Hydrochloric acid

b)

Sulphuric acid

c)

Nitric acid

27.
 is the body's defense against infectious organisms and other invaders. 
a)
respiratory system
b)
endocrine system
c)
immune system
d)
circulatory system
28.
The disease can be prevented by vaccination
a)
Measles
b)
Gonorrhoea
c)
HIV
d)
Salmonella
29.
A substance that is capable of triggering an immune system response.
a)
Antibodies
b)
Antigens
c)
Phagocytes
d)
Lymphocytes
30.

White blood cells help to defend the body against pathogens.


How do the white blood cells do this?


(Select THREE answers)

a)

Clone pathogens

b)

Engulf pathogens

c)

Produce antibiotics

d)

Produce antibodies

e)

Produce antitoxins

31.

Antibiotics are medicines that kill _____________________ .

a)

bacteria

b)

bacteria and viruses

c)

viruses

32.
True or False.  Antibiotics can kill viruses.
a)
True
b)
False
33.
What are antibodies made of?
a)
Carbohydrate
b)
Protein
c)
Polysacchiaride
d)
Lipid
34.

What is an antigen?

a)

A chemical produced by the white blood cells

b)

A chemical on the surface of the pathogen

c)

A mircobe that causes a disease

35.

What is in a vaccine?

a)

small amounts of dead pathogens

b)

large amounts of live pathogens

c)

large amounts of dead pathogens

36.

The vaccine stimulates the white blood cells to produce ___________________ which destroy the virus.

a)

antibiotics

b)

antibodies

c)

drugs

37.
What does a vaccine do?
a)
Gives you immunity
b)
Gets you sick
c)
Cures you
d)
Kills you
38.

Vaccines protect us against diseases.


Against which three diseases does the MMR vaccine protect us?

a)

Rubella

b)

Measles

c)

Meningitis

d)

Mumps

e)

Rabies

39.

Polio is a disease caused by a virus.

In the UK, children are given polio vaccine to protect them against the disease.


It is difficult to kill the polio virus inside the body because the virus

a)

lives inside cells

b)

is not affected by drugs

c)

produces antitoxins

40.

Polio is a disease caused by a virus.

In the UK, children are given polio vaccine to protect them against the disease.


The vaccine contains an ______________

form of the polio virus.

a)

active

b)

infective

c)

inactive

41.

If more people were vaccinated the number of children getting chickenpox would decrease.


What are TWO possible reasons for this decrease?

a)

Drugs to treat chickenpox are no longer effective

b)

Children are less likely to come into contact with someone with the disease

c)

More people will have the correct antibodies

d)

People may catch the disease from the vaccination

e)

People may have a weakened immune system

42.

What is true of white blood cells in a second exposure to infection?

a)

They are produced more rapidly and in greater numbers

b)

They are produced more slowly but in greater numbers

c)

They are produced more rapidly but in lower numbers

43.

What is a painkiller?

a)

A drug that kills bacteria

b)

A drug that causes hallucinations

c)

a drug or a medicine for relieving pain.

d)

A drug only prescribed for adults

44.

What is an antibiotic?

a)

A drug that kills bacteria

b)

A drug that causes hallucinations

c)

a drug or a medicine for relieving pain.

d)

A drug only prescribed for adults

45.

Why it is difficult to develop drugs that kill viruses?

a)

because drugs that kill viruses also damage the body’s tissues.

b)

because viruses mutate quickly

c)

because viruses are small

d)

because viruses cannot reproduce by themselves

46.

Overuse of antibiotics might speed up the development of _________________ strains of ____________________ .

a)

resistant; bacteria

b)

resistant; antibody

c)

immune; antibody

d)

immune; viruses

47.

New strains of pathogens have developed which are resistant to antibiotics.


New strains are produced when pathogens _____________________ .

a)

are short of food

b)

mutate

c)

invade body cells

48.
Which would most likely contribute to antimicrobial resistance?
a)
an increased number of health care facilities
b)
overcrowding and poor sanitation in urban areas
c)
creation of new varieties of vaccinations and medicines
d)
providing more education and training for medical 
49.
Which is the most likely reason for a decline in antibiotic use?
a)
Antibiotics have severe health side effects.
b)
Companies find antibiotics too expensive to produce.
c)
Most health insurance does not cover treatment with antibiotics.
d)
Bacterial infections have become resistant to present antibiotic treatment.
50.

Why is it bad to stop taking your antibiotic before the doctor recommends?

a)

not all of the bacteria is killed, possibly leading to resistance

b)

you will weaken your immune system

c)

you'll get MRSA

d)

you'll gain weight

51.

What is meant by dose?

a)

Side effects making the person ill

b)

The concentration of the drug to be used and how often the drug should be given

c)

Whether the drug works to treat the illness

52.

What is meant by toxicity?

a)

Side effects making the person ill

b)

The concentration of the drug to be used and how often the drug should be given

c)

Whether the drug works to treat the illness

53.

What is meant by efficacy?

a)

Side effects making the person ill

b)

The concentration of the drug to be used and how often the drug should be given

c)

Whether the drug works to treat the illness

54.

Which types of testing is pre-clinical testing?

a)

Testing on cells only

b)

Testing on human volunteers

c)

Testing on mammals only

d)

Testing on cells, tissues or animals

55.

Which types of testing is clinical testing?

a)

Testing on cells only

b)

Testing on human volunteers

c)

Testing on mammals only

d)

Testing on cells, tissues or animals

56.
Why are clinical drug trials important?
a)
They can improve the health of patients
b)
To understand whether the drug causes any harmful side effects
c)
They help test the effectiveness of the drug 
d)
To test whether the drug works and if it causes any harmful side effects
57.

Why are only low doses of a new drug given to human volunteers in the first clinical trial?

a)

To check for any harmful side effects

b)

To work out what the ideal dose should be

58.

Tests on animals


What is the purpose of this stage in trialling a new drug?

a)

Used to find if the drug is toxic

b)

The first stage in the clinical trials of the drug

c)

Used to find the optimum dose of the drug

d)

Used to prove that the drug is effective on humans

59.

Tests on humans using very small quantities of the drug.


What is the purpose of this stage in trialling a new drug?

a)

Used to find if the drug is toxic

b)

The first stage in the clinical trials of the drug

c)

Used to find the optimum dose of the drug

d)

Used to prove that the drug is effective on humans

60.

What is meant by a placebo?

a)

Tablet that does not contain drug

b)

Drug that does not affect body

c)

Tablet that does contain drug

61.
What is a placebo?
a)
A second type of drug given to all people in a trial
b)
A 'dummy' pill given to all people in the trial
c)
A 'dummy' pill given to half of the people in the trial
d)
A drug that will probably harm the patients taking it 
62.

Tests on humans including a placebo


What is the purpose of this stage in trialling a new drug?

a)

Used to find if the drug is toxic

b)

The first stage in the clinical trials of the drug

c)

Used to find the optimum dose of the drug

d)

Used to prove that the drug is effective on humans

63.

What is the placebo effect?

a)

Something that affects the neurological pathways causing people to do nonsensical things.

b)

When someone believes a medication works but the medication was not medicated.

c)

A dangerous experiment that can harm the person that is experimented.

d)

A disease that effects the brain, worse than meningitis

64.

Doctors have developed a new drug.


The new drug has been tested on live animals.


What is the next stage in testing the new drug?

a)

Testing on healthy volunteers

b)

Testing on animal tissues in a laboratory

c)

Testing on patients with the disease

d)

Testing on the whole human population

65.

During the testing, who knows which patients are receiving the placebo?

a)

Only the patients

b)

Only the doctors

c)

Both patients and doctors

d)

Neither patients nor doctors

66.
What is a double blind trial?
a)
The participants take the drug blindfolded
b)
When the scientist and the participants are unaware of whether they are taking the drug or placebo
c)
When the participants choose what they want to take without telling the scientist
d)
When the scientist knows who is taking the drug but the participants don't
67.
Why are double blind trials important?
a)
They make sure the results are fair and unbiased
b)
If the scientist knows who has taken the drug they will lie or change results to show it works
c)
They are the only type of clinical trials available 
d)
Patients might lie about any side effects they feel 
68.
Cancer
a)
Communicable
b)
Non-Communicable
69.
What is cancer?
a)
The heart does not receive enough blood.
b)
Sudden disruption of blood flow to part of the brain.
c)
Blood filled weak spot.
d)
Uncontrolled growth and spread of abnormal cells.
70.

Which of the following are know lifestyle risk factors for various cancers?

Tick all that apply.

a)

smoking

b)

UV Exposure

c)

obesity