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WorksheetsSpring 2022 Phar 505 Exam 1 review
Total questions: 45
Worksheet time: 26mins
RM suffers from constipation. He spends a good deal of money buying OTC MIRALAX and occasionally needs to use a glycerin suppository. He asks the pharmacist for help. The pharmacist looks at her medications and finds that she takes ramipril, lovastatin, cholestyramine, hydralazine, verapamil, and sertraline. Which medication could be contributing to JS's chronic constipation?
Lovastatin
Verapamil
Ramipril
Hydralazine
Sertraline
DT is a 74 YO male with dyslipidemia and prostate enlargement. His only medication is Flomax 0.4 mg daily. He states that he cannot tolerate pravastatin due to muscle aches and joint pain. His cholesterol panel has the following values: Total CH 188 mg/dL, HDL 36 mg/dL, and TG 338 mg/dL. HR 82, BP 129/72 Calculate the patient's LDL cholesterol
64 mg/dL
84 mg/dL
104 mg/dL
114 mg/dL
125 mg/dL
UN is 73 YO male he present to a pharmacy with Rx for Mevacor 40 mg PO with dinner. WOTF is an appropriate generic substitution for Mevacor?
Atorvastatin
Lovastatin
Pravastatin
Simvastatin
A patient experiencing a hypertensive emergency should have blood pressure lowered according to which criteria?
As fast as possible to reach a goal of < 130/80 mmHg
25-30% in the next 10 minutes
Less than or equal to 25% within the first hour
5-10% within the first 4-6 hours
Which medication is appropriate for treatment of hypertension in pregnancy (hcg+)? SATA
Methyldopa
Irbesartan
Labetalol
Spironolactone
JC is a 36-year-old pregnant woman with an active DVT. She takes no other medications and has no significant past medical history. Which agent is the best choice for the initial treatment of her DVT?
Enoxaparin
Aspirin
Warfarin
Dabigatran
KP is 72-year-old woman who presents to the emergency department and reports hematuria for the past 2 days. The patient’s INR is found to be 7.2 and KP reports she may have accidentally taken old 10 mg warfarin tablets instead of her currently prescribed 5 mg tablets for the past week. Which of the following agents would be the most appropriate reversal agent to be used in the case of warfarin overdose?
Phenprocoumon
Protamine sulfate
Vitamin K
Ipecac syrup
Which agent has a delayed onset of anticoagulant effect?
Lovenox
Arixtra
Innohep
Warfarin
A 46 YO patient comes to the clinic for routine follow-up. The patient has HTN and is a smoker. The ASCVD risk score for this patient is 8.5%. Laboratory assessment reveals the following: Na+ 135 mEq/L, K+ 4.5 mEq/L, SCr 2.1 mg/dL, AST 189 units/L, ALT 217 units/L, A1C 6.2%, LDL 140 mg/dL. WOTF would be the best recommendation to treat according to the ACC/AHA Blood Cholesterol Guidelines?
Initiate Zocor 20 mg daily
Initiate atorvastatin 40 mg daily
Initiate Gemfibrozil 600 mg BID
None of the above options are appropriate
WOTF is the generic name of Repatha?
PS. Review all the brands and generic names for dyslipidemia agents!
Praluent
Alirocumab
Evolocumab
Mepolizumab
Which statin is the least potent?
Pravachol
Altoprev
Lescol
Livalo
What effects can Lopid have on lipids? (Select ALL that apply.)
Decreases TG
Increases HDL
Decreases LDL
Increases TG
Decreases HDL
SC comes to the clinic for a follow-up visit for his hypertension and diabetes management. She has been taking four medications to control his blood pressure for a long time. Today, the pharmacist notices a butterfly rash across SC's nose and upper cheeks. Which of the following medications is most likely to cause this side effect?
Enalapril
Eplerenone
Hydrochlorothiazide
Verapamil
Hydralazine
Which of the following lifestyle modifications is important for a patient with chronic hypertension?
P.S review the lifestyle modifications (how much should pt exercise, alcohol limits, DASH diet) in Dr. Patel's handout
Exercise for a minimum of 1.5 hours daily
Limit alcohol consumption to 3 drinks daily
Limit sodium intake to < 1,500 mg daily
Eat a diet low in fiber and low-fat dairy
ST, A 55-year-old male, has a past medical history significant for hypertension, hypercholesterolemia, chronic kidney disease, and peripheral arterial disease. What is JG's goal BP according to 2017 AHA/ACC guidelines?
<130/70 mmHg
<120/80 mmHg
<130/80 mmHg
<140/90 mmHg
What are the individual medicines included in the combination drug Vytorin?
Atorvastatin + Ezetimibe
Simvastatin + Niacin
Simvastatin + Ezetimibe
Lovastatin + Niacin
A patient's triglycerides were recorded at 540 mg/dL. WOTF agents will help to lower triglycerides? (Select all that apply.)
Lovaza
Trilipix
Niacin
Vascepa
WelChol
What effects do statins have on cholesterol values? (Select ALL that apply.)
Raises HDL
Lowers HDL
Increase triglycerides
Decrease LDL
Lowers triglycerides
WOTF is the generic name for Livalo?
Fluvastatin
Lovastatin
Pravastatin
Pitavastatin
Rosuvastatin
What other names are niacin known by? (Select ALL that apply.)
B1
B2
B3
Biotin
Nicotinic Acid
TE has systolic heart failure with an ejection fraction of 33%. Which of the following medications could potentially worsen his heart failure condition?
Amlodipine
Verapamil
Chlorthalidone
Spironolactone
Treating hypertension will reduce the risk of which of the following? (select all that apply)
Cancer
Stroke
Thyroid disorders
Heart disease
Kidney disease
A 56-year-old female has diabetes and COPD. She is already using a thiazide diuretic, a calcium channel blocker, and an angiotensin receptor blocker but her blood pressure remains elevated at a range of 143-153/83-93 mmHg. She will be started on beta-blocker therapy. Which of the following drugs is most appropriate?
Timolol
Carvedilol
Metoprolol
Propranolol
AH is a 34-year-old female with a history of type 2 diabetes, hypertension, and heart failure. She was recently initiated on metoprolol succinate. What important counseling point should AH receive about metoprolol?
It can mask the symptoms of hypoglycemia
It can mask the symptoms of hyperglycemia
It is contraindicated with a history of heart failure
It can enhance the effects of metformin
WOTF statin regimens are considered high-intensity statin therapy? (Select ALL that apply.)
PS. Also review who needs to be on high-intensity
Crestor 40 mg daily
Lipitor 20 mg daily
Rosuvastatin 10 mg daily
Lipitor 40 mg daily
Zocor 40 mg daily
AS 48 YO female her PCP prescribed her Lovaza what should be dispensed with caution to a patient with this allergy:
Fish or shellfish
Dairy
Sulfa
Peanuts
Which lipid-lowering therapy is contraindicated in Pts w/ a history of gallstones?
Tricor
Statins
Ezetimibe
Bile acid resins
Fish oils
Control of the following conditions will help to improve PAD?
Hypertension
Diabetes
Dyslipidemia
Smoking cessation
Which of the following medication has the best efficacy for claudication symptoms in PAD?
Trental
Cilostazol
What is the Cilostazol dose when co-administer with Omeprazole?
Can you explain why?
What benefit can Cilostazol provide for patients with PVD?
100mg BID
100mg QD
50mg BID
50mg QD
What labs do you use to monitor efficacy of Heparin?
PT
INR
APTT
ESR
Which of these medications cause a major drug drug interaction with warfarin?
Fluticasone
Bactrim
Fluzone
Bacitracin
Which medications should be avoided with Rivaroxaban? SATA
Rifampin
Carbamazepine
Ritonavir
Ketoconazole
What is the duration of anticoagulation for a patient with 1st episode proximal DVT that is provoked by a surgery?
5 days
1 week
1 month
3 months
A patient has been recently diagnosed with DVT. The team wants to start him on Apixaban. Which of the following is true?
Must use a parenteral anticoagulant for 5 days before switching over to Apixaban
Start Apixaban on day 1 of diagnosis
Must overlap apixaban with parenteral anticoagulant for at least 5 days
State the antidote for the following agents:
Warfarin
Heparin
Enoxaparin
Dabigatran
Apixaban
Rivaroxaban
Edoxaban
The lower the INR, ...
The thinner is the blood
The thicker is the blood
The higher is risk of bleeding
The lower is the risk of clotting
Which of the following medications can be used in place of Heparin in patient who developed Heparin Induced Thrombocytopenia? SATA
Bivalirudin
Apixaban
Argatroban
Enoxaparin
AA presents to the clinic with unilaterial right leg swelling around the ankle, tenderness for two days after his long-hour flight from Asia. His d-dimer test is elevated. What is the most probable diagnosis?
Congestive heart failure
Deep vein thrombosis
Pulmonary embolism
Ant bite
Which of the following medication is not safe to be used during pregnancy? SATA
Enoxaparin
Apixaban
Unfractionated Heparin
Warfarin
Ms K is a 35 years old male with a history of recurrent DVT (first episode in 2019 and second episode in 2020). He was started on Apixaban after first DVT with some adherence issues and switched to warfarin after the 2nd DVT for closer monitoring. Today he presents to the clinic with INR of 1.8. What is his therapeutic INR goal?
Between 1.0 and 2.0
Between 1.5 and 2.5
Between 2.0 and 3.0
Between 2.5 and 3.5
Which of the following are modifiable risk factors of hypertension? SATA
P.s. review slide 42 in Dr. Patels handout for risk factors
Smoking history or being around with someone who smoke
Diabetes
Male
Overweight
Mr. Sunny is a 54 years old male in your hypertension clinic. He comes to the followup appointment and is excited to know that he has lost 2 kg after eating healthier and exercise. What is the expected reduction in systolic bp with this weight drop?
0.5 mmHg
1 mmHg
2 mmHg
10 mmHg
A 40 years old Asian female with stage 1 hypertension for over 1 year and a ASCVD risk of 5%. The physician would like to start her on an antihypertensive. She also has a history of diabetes. Which medication class will be most beneficial?
P.S review TBL case and compelling indications for each antihypertensive med class
Loop diuretic
Aldosterone antagonist
ACE inhibitor/ ARB
Beta Blocker
73How would you classify a patient whose blood pressure are as followed:
Reading 1: 128/ 73 mmHg
Reading 2: 124/68 mmHg
PS. Please review the stage criteria to classify hypertension
Normal
Elevated
Stage 1
Stage 2
