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IS POST QUIZ MODULE 1

Total questions: 50

Worksheet time: 34mins

Name
Class
Date
1.

It is the process of decreasing the pathogenicity or vitality of a microorganism.

a)

Variolation

b)

Attenuation

c)

Vaccination

d)

Immunization

2.
An organism that enters a life form and causes disease or sickness is a/an:
a)
macrophage
b)
pathogen
c)
vaccine
d)
flu
3.
This refers to the type of immunity developed from exposure to a pathogen:
a)
active acquired immunity
b)
passive acquired immunity
c)
innate immunity
d)
attenuated immunity
4.
A type of cell that "digests" pathogens is known as a/an:
a)
helper T cell
b)
macrophage
c)
suppressor T cell
d)
plasma cell
5.
This gland, located anterior to the heart, but posterior to the sternum, is the lymphatic site where T cells are produced and mature:
a)
tonsils
b)
trachea
c)
thymus
d)
thalamus
6.
A type of T cell that destroys infected cells is a:
a)
cytotoxic T cell
b)
helper T cell
c)
memory T cell
d)
suppressor T cell
7.
The organism that is infected by a pathogen/antigen is known as the:
a)
survivor
b)
infectee
c)
source
d)
host
8.
Virus replication may be slowed down by the natural production or administration of this signaling protein:
a)
interferon
b)
histamine
c)
plasma cell
d)
antibodies
9.
The first line of defense against antigen is the _________ system.
a)
respiratory
b)
digestive
c)
integumentary
d)
lymphatic
10.
Viruses, like bacteria, can be successfully treated with doctor prescribed antibiotics.
a)
TRUE
b)
FALSE
11.
Signs of an inflammatory reaction include redness, swelling, heat, and itch.
a)
TRUE
b)
FALSE
12.

This helps to maintain the integrity of the lining of the intestines, thereby helping to boost immunity

a)

Probiotics

b)

Selenium

c)

Vitamin A

d)

Fatty Acids

13.

In lymph nodes

a)

white blood cells mature into T cells.

b)

lymph drains back into the circulatory system.

c)

old and damaged red blood cells are destroyed.

d)

B and T cells gather and attach to foreign antigens.

14.

An inflammation reaction involves the

a)

release of histamines.

b)

agglutination of bacteria.

c)

production of immunoglobulin.

d)

vaseconstriction of blood vessels.

15.

White blood cells that are involved in the third line of defence of the immune system include

a)

mast cells.

b)

eosinophils.

c)

lymphocytes.

d)

macrophages.

16.

First-line defences that mammals have against invasion by disease-causing bacteria include

a)

lysozymes.

b)

interferons.

c)

antibodies.

d)

cytotoxic T cell.

17.

Radioimmunoassay was discovered by?

a)

Kohler and Milstein

b)

Robert Klaus

c)

Rosalyn Yallow

d)

Robert Porter

18.

This term refers to the condition of being resistant to an infection.

a)

Immune Response

b)

Immunology

c)

Immunity

d)

Inflammation

19.

All of the following are characteristics of innate immunity except?

a)

First line of defense

b)

Second line of defense

c)

Third line of defense

d)

Blocks or limits access of foreign agents in the body

20.

Factors that may affect immunity of an individual includes all of the following except?

a)

Genetic Determinants

b)

Stress

c)

Age

d)

Nutrition

e)

None of these

21.

Which of the following is an external component of the innate immunity?

a)

PMN's

b)

Phagocytosis

c)

Inflammation

d)

Mucus

e)

Macrophages

22.

This cell when activated responds on acute type of infection.

a)

Macrophages

b)

Monocyte

c)

Lymphocytes

d)

Neutrophils

23.

This component of the neutrophil helps degrades the bacterial wall.

a)

Myeloperoxidase

b)

Muramidase

c)

Lactoferrin

d)

Histamine

24.

This protein binds iron and competes with bacteria for iron thereby inhibiting their growth.

a)

Lysozyme

b)

Myeloperoxidase

c)

Lactoferrin

d)

Hemoglobin

25.

This granule found on eosinophils helps in the successful killing of parasites.

a)

Myeloperoxidase

b)

Major Basic Protein

c)

Bence Jones Protein

d)

Mannan Binding Protein

26.

These cells are predominant on chronic type of infection or inflammation.

a)

Monocytes

b)

B cells

c)

T cells

d)

Neutrophils

27.

What is the macrophage found on kidneys?

a)

Mesangial cells

b)

Littoral

c)

Alveolar Macrophage

d)

Microglial

e)

Hoff bauer

28.

All of the following are antigen-presenting cells except?

a)

Macrophages

b)

B cells

c)

Dendritic cells

d)

Natural Killer Cells

29.

This cell is the most effective antigen presenting cell of the immune system.

a)

Macrophages

b)

Natural Killer cells

c)

Dendritic Cells

d)

B cells

30.

A type of dendritic cells that are found on the secondary lymphoid tissues and the thymus.

a)

Interdigitating dendritic cells

b)

Interstitial dendritic cells

c)

Langerhans cells

d)

All of the above

31.

This type of cell is the body's first line of defense against virally infected cells.

a)

Cytotoxic T cells

b)

Dendritic Cells

c)

Lymphokine Activated Killer Cells

d)

Monocytes

32.

This cationic substance is release by platelets that has bactericidal activity on gram positive bacteria.

a)

Interferon

b)

Interleukins

c)

Betalysin

d)

Histamine

33.

These cells are produced by WBCs that acts as signal molecules in case of infection.

a)

Tumor Necrosis Factor

b)

Interleukins

c)

Betalysins

d)

Complement

34.

AKA immuninterferon and are produced by T cells and NK cells which is a major macrophage activator, responsible for immunoregulation.

a)

IFN-βeta

b)

IFN-alpha

c)

IFN-Gamma

d)

None of the above

35.

The major vascular events that happens during inflammation includes all of the following except?

a)

Increased capillary permeability caused by retraction of endothelial cells lining the vessels causing swelling and pain

b)

Increase blood supply to the infected area causing redness and heat

c)

Migration of WBCS, mainly neutrophils from the capillaries to the surrounding tissue

d)

Migration of macrophages to the injured area

e)

Formation of abscess with some loss of function

36.

Negative acute phase reactant that decreases during inflammation.

a)

C-reactive Protein

b)

Alpha 1-globulin

c)

Albumin

d)

Fibrinogen

37.

First described by Elie Metchnikoff which results in the destruction of foreign cells and organisms

(a)  

38.

The process of squeezing movements of WBCs from the blood through the blood vessel walls into the tissues is called?

(a)  

39.

If there is impaired random movement and chemotaxis of WBCs, these condition is called?

a)

Job Syndrome

b)

Chronic Granulomatous Disease

c)

Lazy Leukocyte Syndrome

d)

Impaired Chemotaxis

40.

This WBC recognition method involves direct phagocytosis via recognition of pathogen associated molecular patterns.

a)

Primitive Pattern recognition Receptors

b)

Opsonization

c)

Boyden Chamber

d)

Migration via Agarose Gel

41.

If there is defective lysosomal enzymes of WBCs, this condition is called?

(a)  

42.

Major characteristics of adaptive immunity includes?

a)

MEMORY

b)

SPECIFICITY

c)

DEVELOPS AFTER EXPOSURE

d)

ACQUIRED

e)

ALL OF THE ABOVE

43.

Adaptive humoral immunity is mediated by?

(a)  

44.

Immunity that occurs when patient recovers from infection.

a)

Artificial Active

b)

Natural Active

c)

Artificial Passive

d)

Natural passive

45.

Injection of Hepa B immuneglobulin is an example of what immunity?

a)

Natural Passive

b)

Natural Active

c)

Artificial active

d)

Artificial Passive

46.

These specialized cells “turn off” B lymphocytes so they can no longer cooperate with normal T cells to produce an immune response.

a)

Helper T cells

b)

Cytotoxic T cells

c)

B cells

d)

NK cells

47.

AKA antigen processor and presenter for circulating pool of B lymphocytes which responds with antibody production.

a)

CD 4

b)

CD 8

c)

CD 25

d)

CD 56

48.

This acts as oligoclonal activators of lymphocytes.

(a)  

49.

Most potent activator of B and T lymphocytes.

(a)  

50.

End products of T cell activation is?

a)

Plasma cells

b)

Antibodies

c)

Cytokines

d)

WBC production