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SIMPICSED_Training

Total questions: 48

Worksheet time: 36mins

Name
Class
Date
1.

Localized tissue damage caused by B.pertussis is mediated by what substance?

(a)  

2.

Name one example of Brucella species which commonly cause disease in human!

(a)  

3.

Beside the increase of localized inflammation with the recruitment of T cells and natural killer (NK) cells into the area of the infected macrophages, what does TNF-α do in a Mycobacterium tuberculosis infection?

(a)  

4.

In Neisseria gonorrhoeae, besides mediating the attachment to noncilliated human cell, what is the function of Pilin?

(a)  

5.

What is the function of transferrin in N.gonorrhoeae?

(a)  

6.

Which antibiotics can be used initially for N.meningitidis infection?

(a)  

7.

Name one example of nontreponemal serology test!

(a)  

8.

Name one example of treponemal serology test!

(a)  

9.

What conditions which can cause false positive in nontreponemal test?

(a)  

10.

What are the laboratory criteria for diagnosis of Lyme disease?

(a)  

11.

In S.aureus, what is the possible resistance mechanism against Fluoroquinolone antibiotic?

(a)  

12.

Name the example of efflux pump of the outer membrane in P.aeruginosa, which able to remove a heterogeneous group of molecules including antimicrobials from its intracellular space!

(a)  

13.

Porin changes in Acinetobacter spp are associated with resistance to what group of antibiotic?

(a)  

14.

Methicillin resistance in S. aureus (MRSA) is due to the expression of PBP2a. This low-affinity PBP is encoded by the what gene?

(a)  

15.

According to Ambler Class, the Carbapenemase in Gram negative bacilli such as K.pneumoniae belongs to which class?

(a)  

16.

What is/are the molecule produced after a glycolysis reaction of a mole of glucose?

(a)  

17.

Continuous septicemia occurs primarily in…

(a)  

18.

In pathogenesis of pulmonary tuberculosis, alveolar macrophages, epithelioid cells, and Langhans giant cells (fused epithelioid cells) with intracellular mycobacteria form the central core of a necrotic mass that is surrounded by a dense wall of macrophages and CD4, CD8, and NK T cells. What is this structure called and what does its function?

(a)  

19.

Resistance to ampicillin among E. coli and K.pneumoniae is mediated by?

(a)  

20.

This picture shows the satellite phenomenon of the H.influenzae colonies among the S.aureus colonies. What do the S.aureus provide for the growth of H.influenzae?

(a)  

21.

C.difficile produces two toxins. Name one of them!

(a)  

22.

What does the toxin A of C.difficile act?

(a)  

23.

What does toxin B of C.difficile act?

(a)  

24.

What does Alpha toxin A of C.perfringens act?

(a)  

25.

What is Beta toxin of C.perfringens responsible for?

(a)  

26.

The characteristic face of tetanus patient that is resulted from the sustained contraction of the facial muscles is known as?

(a)  

27.

Specific cultivation media for the growth of Salmonella sp and Shigella is?

(a)  

28.

Which molecular techniques that can be used for comparison of DNA? (can be more than 1)

a)

RFLP

b)

DNA Electrophoresis

c)

PFGE

d)

Dot blot

e)

SDS-PAGE

29.

Cross-linking of peptidoglycan chain is mediated by which enzyme?

(a)  

30.

Germination of bacterial spores into the vegetative state is stimulated by?

a)

disruption of the outer coat by mechanical stress,

b)

pH

c)

heat

d)

water and a triggering nutrient (e.g alanine)

e)

UV light

31.

The component of bacterial spore include which of the following (can be >1)

a)

Exosporium

b)

Cortex

c)

Core

d)

Endosporium

e)

Septum

32.

Fill in the blank!

High concentrations of (a)   in the spore bind calcium and stabilize the contents

33.

Phenolics has germicidal properties against?(Answer can be >1)

a)

Bacteria

b)

Mycobacteria

c)

Bacterial spores

d)

Fungi

34.

The following staining methods is/are classified as differential stain. (Can be >1)

a)

India ink

b)

Gram stain

c)

Trichrome stain

d)

Lugol iodine

e)

Toluidine blue O stain

35.

Which of the following is NOT included in 5 moments of hand hygiene?

a)

Before touching a patient

b)

After body fluid exposure

c)

Before touching the computer in the nurse station

d)

After touching patient surroundings

36.

Resistance against ampicillin in Enterococcus faecium is mediated by....

a)

Enzimatic modification

b)

Altered peptidoglycan cross-link target

c)

Mutation in Pbp5

d)

Production of beta-lactamase enzyme

e)

Efflux pump

37.

Listeria monocytogenes exhibits (a)   feature when grown on sheep blood agar plates.

38.

Listeria monocytogenes is able to adhere to host cell via the interaction of (a)   with glycoprotein receptors on the host cell surface.

39.

The genes in L.monocytogenes which responsible for membrane lysis, intracellular replication, and directional movement are clustered together and regulated by a single gene, namely:

(a)  

40.

The gold standar for detection of diphtheria toxin is:

(a)  

41.

The green pigmentation of P.aeruginosa colony on nutrient agar is resulted from the production of these two water-soluble dyes:

a)

Blue pyocyanin

b)

Blue chromocyanin

c)

Yellow fluorescein

d)

Yellow pyochromosiderin

42.

Which of these antibiotic susceptibility features that can distinguish Burkholderia sp from P.aeruginosa?

a)

P.aeruginosa is uniformly resistant against carbapenems

b)

Burkholderia sp is resistant to trimethoprim-sulfamethoxazole

c)

P.aeruginosa is susceptible to trimethoprim-sulfamethoxazole

d)

Burkholderia sp is susceptible to trimethoprim-sulfamethoxazole

43.

These following antibiotics are still susceptible against Moraxella: (can be >1)

a)

Penicillin

b)

Ceftriaxone

c)

Tetracycline

d)

Erythromycin

e)

Amoxicillin

44.

What is the causative agent of cat-scratch disease?

(a)  

45.

In P.aeruginosa, resistance against fluoroquinolone can be mediated through this/these mechanism(s). (Can be >1)

a)

Efflux pump

b)

Change in outer membrane permeability

c)

Altered target

d)

Porin alteration

e)

Mutation of gene encoding DHPS

46.

These following antibiotics can be used for treatment of tularemia.(Can be >1)

a)

Cefazolin

b)

Gentamicin

c)

Cefoperazone

d)

Doxycycline

e)

Ciprofloxacin

47.

Which of the following antibiotic is/are effective against Mycoplasma? (can be >1)

a)

Carbapenems

b)

Vancomycin

c)

Erythromycin

d)

Tetracycline

e)

Ampicillin

48.

What is the vector for the causative agent of Rocky Mountain spotted fever?

(a)