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REVISION CHAPTER 4, 5 & 6 SB015

Total questions: 100

Worksheet time: 55mins

Name
Class
Date
1.

What are alleles?

a)

A basic hereditary unit located on a specific locus of a chromosome.

b)

An alternative form of a gene, located at a specific position on a specific chromosome.

c)

Consists of a DNA segment that encodes particular proteins.

d)

A characteristic passed from parent to offspring.

2.

Which is NOT TRUE about genes?

a)

Represent by alphabets.

b)

To determines a specific characteristic in the organism.

c)

Consists of a DNA segment that encodes particular proteins.

d)

A basic hereditary unit located on a specific locus of a chromosome

3.

An allele that is fully expressed in the phenotype of a heterozygote.

a)

recessive allele

b)

dominant allele

c)

heterozygote allele

d)

homozygote allele

4.

An allele whose trait cannot shows up in heterozygous form.

a)

homozygote allele

b)

dominant allele

c)

recessive allele

d)

heterozygote allele

5.

What is the definition of the phenotype?

a)

The physical characteristics determined by the genotypes.

b)

The genetic makeup of an organism

c)

The letters eg, Aa

d)

combination of allele of an individual.

6.

What is the definition of a genotype?

a)

A combination of allele an individual.

b)

The physical traits of an organism.

c)

When one allele is dominant and one allele is recessive.

d)

When both alleles are dominant.

7.

Which genotype represent by heterozygous

a)

AA

b)

Bb

c)

bb

d)

Ab

8.

What is it called when a gene carries two of the identical alleles?

a)

Homozygous

b)

Heterozygous

c)

Genotype

d)

Phenotype

9.

Based on the diagram, how many loci are on the chromosome?

a)

8

b)

4

c)

2

d)

10

10.

A test cross is ..

a)

A cross between organisms of the same generation

b)

A cross between organisms of the different generation

c)

A cross between an organism of dominant phenotype and another organism of dominant phenotype but of unknown genotype.

d)

A cross between an organism of recessive phenotype and another organism of dominant phenotype but of unknown genotype

11.

Mendel's experiment on Pea plant focused on which type of characteristics? (choose 3)

a)

flower colour

b)

height of plant

c)

length of pea pod

d)

Pea pod's colour

12.

What does the law of segregation state?

a)

Separate genes are passed independently from each other, from parent to offspring.

b)

Each characteristic is controlled by two alleles which will segregate and each allele is transferred to each gamete

c)

Two alleles is transferred to each gamete during meiosis

d)

A recessive allele is expressed less than a dominant allele.

13.

The Law of Independent Assortment states:

a)

most genes are inherited together

b)

organisms inherit two alleles (one from each parent) during sexual reproduction.

c)

recessive genes can never be expressed

d)

each pair of alleles segregates independently of other pairs of alleles during gamete formation

14.

This type of inheritance shows both alleles are fully expressed in the heterozygous form

a)

complete dominance

b)

incomplete dominance

c)

codominant alleles

d)

dominant allele

15.

Progenies with heterozygous genotypes have intermediate phenotypes. What type of inheritance shown?

a)

sex-linked inheritance

b)

complete dominant

c)

codominant alleles

d)

incomplete dominant alleles

16.

What type of inheritance described by one gene controlled by more than two alleles that can occupy same locus and all alleles control the same characteristic.

a)

multiple alleles

b)

incomplete dominant alleles

c)

codominant alleles

d)

multiply alleles

17.

What is it called when two or more gene that determine different characteristics located on the same chromosome?

a)

Multiple allele

b)

Polygenes

c)

Linked genes

d)

Dihybrid cross

18.

Linked genes are...

a)

genes that can not be separated independently during meiosis

b)

genes that follow the Law of Independent Assortment

c)

2 or more genes located on the same chromosome.

d)

genes that are located on sex chromosome

19.

Which is NOT TRUE about linked genes?

a)

Genes located on different locus on the same homologous chromosome

b)

Genes located on different locus on the different homologous chromosome

c)

Representative symbol for genotype is oblique

d)

They do not follow the Law of independent assortment

20.

Effect of crossing over, it will produce a slightly different gamete than a parental gamete which is known as ______________

a)

Combination gamete

b)

Determinants gamete

c)

Recombinant gamete

d)

Co-dominants gamete

21.

The reason for new combinations of gamete in linked genes because _________________

a)

Segregation

b)

Recombinants

c)

Crossing over

d)

Independent assortment

22.

A gene located on either sex chromosome is called _________

a)

Autosome linked genes

b)

Sex-linked genes

c)

Linked genes

d)

Sex genes

23.
If a gene is found only on the X chromosome and not the Y chromosome, it is said to be 
a)
sex-linked trait
b)
polygenic trait
c)
codominant trait
d)
incomplete dominance trait
24.

Sex linked recessive inheritance will..

a)

only express its phenotype in male

b)

express the recessive phenotype in homozygous female only

c)

express the recessive phenotype in hemizygous male and homozygous female

d)

express the recessive phenotype in homozygous male and hemizygous female

25.

Males are more likely to suffer from a sex-linked disease or disorder because

a)

males have less DNA

b)

males is heterogamete

c)

males are the weaker sex

d)

males have 1 X chromosome, so the disorder is more likely to be expressed

26.

Hemophilia is a recessive x-linked disorder.

Which genotype represents a female who is a carrier for hemophilia?

a)

XHXh

b)

XhXh

c)

XHXH

d)

XhY

27.
Hemophilia is a recessive x-linked disorder.
Which genotype represents a male with hemophilia?
a)
XHXh
b)
XhXh
c)
XHY
d)
XhY
28.

Polygenes is when... (choose 3)

a)

All traits are qualitative

b)

All traits are quantitative

c)

All genes control the same characteristic

d)

One characteristics is controlled by many genes (2 or more genes)

29.

What type of inheritance is determined by multiple genes located at different loci on different chromosomes?

a)

Polygenes

b)

Linked genes

c)

Codominance

d)

Incomplete dominance

30.

An example of polygenes is

a)

Tongue rolling

b)

ear lobe attachment

c)

skin colour in humans

d)

eyes colour in humans

31.

Determine the sequence of genes A, B, C, and D if the distance from A-C is 17 units, A-B is 25 units, A-D is 37 units, B-C is 8 units and B-D is 12 units. The order would be as follows:

a)

A, B, C, D

b)

A, C, B, D

c)

D, C, A, B

d)

C, A, B, D

32.

In Pisum sativum, the genes for purple colour flower (R) and round seeds (Q) are dominant over the genes for white colour flower (r) and wrinkled seed (q). Heterozygous were test crossed and the result are shown in the TABLE. Calculate the distance between flower colour and seed shape genes.

a)

17.36 map unit

b)

82.64 map unit

c)

46.53 map unit

d)

53.47 map unit

33.

Genetic equilibrium in a population refers to ..

a)

constant allele frequencies in one generation to next generations

b)

constant mutation rate in the population

c)

equal numbers of dominant and recessive alleles

d)

equal numbers of males and females

34.

A gene pool consists of ..

a)

all the alleles selected by natural selection

b)

all the alleles present in a population

c)

the entire genome of a sexually reproducing organism

d)

the frequencies of the alleles for a gene locus within a population

35.

When a gene pool of a population changed, it means ...

a)

number of organims in the population changes

b)

organisms in the population are breeding randomly

c)

the population is in genetic equilibrium

d)

the population is undergoing evolution

36.

In a population of 1000 dragonfly with genotype

GG = 500, Gg = 400 and gg = 100. Calculate the frequency of recessive allele, g.

a)

0.8

b)

0.3

c)

0.2

d)

0.03

37.

In a population of 250 rats, calculate the gene pool for length of fur.

a)

250

b)

500

c)

1000

d)

125

38.

In a population of 250 rats, the recessive allele frequency of short fur is 0.25. What is the recessive allele frequency in the next generation if the population is considered to be in genetic equilibrium?

a)

0.25

b)

0.5

c)

0.3

d)

0.75

39.

In a population of 1000 dragonfly with genotype

GG = 500, Gg = 400 and gg = 100. Calculate the frequency of dominant allele, G.

a)

0.6

b)

0.5

c)

0.7

d)

0.07

40.

Which of these factors that is the main cause of change in gene pool?

a)

mutation occur

b)

migration occur

c)

genetic drift occur

d)

the population size is small

41.

Which of the following, describes a frequency of homozygous dominant genotype?

a)

Total number of GG individuals

Total number of all individuals in a population

b)

Total number of Gg individuals

Total number of all individuals in a population

c)

Total number of gg individuals

Total number of all individuals in a population

d)

Total number of GG + Gg individuals

Total number of all individuals in a population

42.

in 2000 butterfly population, the frequency of recessive allele is 0.04. What is total number of dominant allele in the population.

a)

160

b)

4000

c)

3840

d)

80

43.

In 2000 population of rats, the frequency of the heterozygous genotype, rr is 0.09 and Rr is 0.42. What is the frequency of individuals that are homozygous for the dominant allele?

a)

0.01

b)

0.58

c)

0.21

d)

0.49

44.

Which of the following is not a requirement for maintaining the Hardy-Weinberg equilibrium?

a)

An increasing mutation rate

b)

Random mating

c)

Large population size

d)

No migration

45.

In a 1200 students in KMM, with genotype RR = 600, Rr = 400 and rr =200. Calculate the frequency of individuals that carries one recessive allele.

a)

0.17

b)

0.33

c)

0.5

d)

0.16

46.

In a type of mammal, genes for the albino are recessive to the brown hair. It is found that 150 out of 500 mammals are albinos. What is the frequency of the homozygous recessive in that population?

a)

0.2

b)

0.3

c)

0.4

d)

0.5

47.

The sum total of all genes in a population is known as the __________________.

a)

Genetic equilibrium

b)

Genetic drift

c)

Gene pool

d)

Gene frequency

48.
Which sequence of DNA bases would pair with this partial strand
CAT TCA CTG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
49.
Which of the following units are repeatedly joined together to form a strand of DNA?
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides
50.
The enzyme that unwinds the DNA to prepare for replication
a)
helicase
b)
replicase
c)
polymerase
d)
synthase
51.

DNA replication results in semi conservative which produces two DNA molecules,

a)

each one with two original strands

b)

each one with two new strands

c)

each one with one new strand and one original strand

d)

one with two new strands and the other with two original strands

52.
order of replication
a)
3, 4, 2, 1
b)
3, 1, 4, 2
c)
2, 1, 4, 3
d)
3, 4, 1, 2
53.

A process in which two new identical DNA is copied from the original DNA.

a)

Replication

b)

Translation

c)

Transcription

54.
In what phase of the cell cycle does DNA replication take place?
a)
G1
b)
S
c)
G2
d)
M
55.
Which enzyme is responsible for adding nucleotides?
a)
Topoisomerase
b)
DNA Polymerase
c)
Ligase
d)
Primase
56.

The scientists who prove DNA replication to be semi conservative by their experiment.

a)

none of these

b)

Hershey and Chase

c)

Avery et.al

d)

Meselson and Stahl

57.
Based on the diagram, how many origins of replication are represented?
a)
1
b)
2
c)
3
d)
4
58.
Based on the diagram, the enzyme (represented in gray) is most likely...
a)
DNA polymerase
b)
DNA Ligase
c)
Nuclease
d)
Helicase
59.
What will the first four bases of the new DNA strand look like if copying the template strand?
a)
TGGT
b)
ACCA
c)
GTTG
d)
CAAC
60.

Who is prove that DNA carry genetic information? (answer can be more than one)

a)

Griffith

b)

Avery et.al

c)

Hershey and Chase

d)

Meselson and Stahl

61.

What is central dogma?

a)

flow of genetic information in the biological information

b)

genetic information that carried in DNA molecule

c)

one gene encodes for one polypeptide

62.

Genetic information that carry in DNA is in form of ....

a)

protein

b)

gene

c)

code

d)

enzyme

63.

DNA carries genetic information to be translated to synthesized ___________ chain

a)

polynucleotide

b)

polysaccharide

c)

polypeptide

d)

polyribosome

64.

A specific gene on DNA will be ________ to form a single strand of mRNA.

a)

replicated

b)

replaced

c)

translated

d)

transcribed

65.

What is the result of experiment conducted by Beadle and Tatum?

a)

one gene one polypeptide

b)

one gene one enzyme

c)

one gene one mRNA

66.

What is the function of single-strand binding protein?

a)

hold the separated DNA strands apart

b)

helps relieve the strain caused by unwinding

c)

unwinding double helix of DNA

d)

hold the DNA nucleotides in template

67.

What is the function of topoisomerase?

a)

hold the separated DNA strands apart

b)

helps relieve the strain caused by unwinding

c)

unwinding double helix of DNA

d)

hold the DNA nucleotides in template

68.

What is the function of primase?

a)

catalyze the formation of RNA primer

b)

catalyze the joining of all Okazaki fragments

c)

catalyze unwinding double helix of DNA

d)

catalyze addition of free DNA nucleotides

69.

What is the function of DNA ligase?

a)

catalyze the formation of RNA primer

b)

catalyze the joining of all Okazaki fragments

c)

catalyze unwinding double helix of DNA

d)

catalyze addition of free DNA nucleotides

70.

What is the function of DNA polymerase I?

a)

add RNA nucleotides to the template

b)

replace DNA nucleotides with RNA nucleotides

c)

add DNA nucleotides to the template

d)

replace RNA nucleotides with DNA nucleotides

71.

Which of the following are produced when DNA molecules undergoes replication?

a)

single strand RNA

b)

one double stranded DNA

c)

two new DNA molecules

d)

excessive DNA

72.

Which of the following best show the flow of genetic information within a cell?

a)

RNA > DNA > protein > trait

b)

RNA > DNA > glycoprotein > trait

c)

DNA > protein > trait

d)

DNA > RNA > protein > trait

73.
In RNA, Uracil pairs with ______. 
a)
cytosine
b)
adenine
c)
guanine
d)
thymine
74.
The process to go from DNA to mRNA is _______
a)
translation
b)
transcription
c)
replication
75.
The process to go from mRNA to a protein is called ____
a)
transcription
b)
rRNA
c)
replication
d)
translation
76.
DNA holds the code for
a)
lipids
b)
carbohydrates
c)
protein
d)
sugar
77.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
78.
The main function of tRNA is to...
a)
carry a message that, when translated, forms proteins
b)
form a portion of ribosomes
c)
string together complementary RNA and DNA strands
d)
bring amino acids from the cytoplasm to the ribosomes
79.

What amino acid is represented by the codon AUG?

a)

Phenylalanine

b)

Tyrosine

c)

Methionine

d)

Stop codon

80.
What process is going on in this photo? 
a)
Transcription 
b)
Translation 
c)
Replication 
d)
All the above 
81.
Which component of DNA determines the traits of an organism? 
a)
Nitrogen Bases
b)
Sugar-Phosphate Backbone
c)
Hydrogen bonds
82.

What is the location in the cell for translation?

a)

nucleus

b)

mitochondria in cytoplasm

c)

ribosome in cytoplasm

d)

chloroplast in cytoplasm

83.
What is the three base sequence of mRNA that codes for a single amino acid?
a)
Anticodon
b)
Codon
c)
Protein
84.
What is the location in the cell for transcription?
a)
nucleus
b)
cytoplasm
c)
ribosome
d)
mitochondria
85.
Translation is the process where
a)
mRNA is created in the Nucleus
b)
mRNA is decoded to form a protein 
c)
glucose molecules are made
d)
is where lipids are synthesised
86.
Does the order of amino acids in a protein matter?
a)
YES!
b)
NO!
87.

What process is happening in the diagram?

a)

transcription

b)

translation

c)

dna replication

d)

mitosis

88.

Which is the following are stop codon?

(answer can be more than ONE)

a)

AUG

b)

UUA

c)

UGA

d)

UAG

89.

Which one of the following is translocate during translation?

a)

Ribosome

b)

mRNA

c)

Aminoacyl-tRNA

d)

polypeptide chain

90.

What is the protein involved during termination stage of translation?

a)

Restriction enzyme

b)

Release enzyme

c)

Release factor

d)

Repressor protein

91.

Which one is correct about statement of codons are degenerate?

a)

One amino acid encoded by more than one codon

b)

One codon encodes for more than one amino acid

c)

Many amino acids encoded by one codon

92.

tRNA that carry amino acid is called as

a)

aminoacyl tRNA synthetase

b)

aminoacyl tRNA

c)

aminoacid tRNA

d)

aminoacid tRNA complex

93.

Transcription begins at sequence called

a)

intron

b)

origin

c)

promoter

d)

start codon

94.

All of the following are components of the lac operon except

a)

regulatory gene

b)

Promoter

c)

operator

d)

structural gene

95.

What happen to lac operon if repressor protein is in inactive form

a)

lac operon activated

b)

lac operon inactivated

96.

In the lac operon the inducer is

a)

allolactose

b)

glucose

c)

galactose

d)

all of the above

97.
A protein that binds to the operator and blocks the RNA polymerase
a)
regulator
b)
repressor
c)
activator
d)
corepressor
98.

Determine the sequence of genes A, B, C, and D if the distance from A-C is 17 units, A-B is 25 units, A-D is 37 units, B-C is 8 units and B-D is 12 units. The order would be as follows:

a)

A, B, C, D

b)

A, C, B, D

c)

D, C, A, B

d)

C, A, B, D

99.

In a population of cows at genetic equilibrium, 750 cows have long horns (dominant trait), while remaining 250 cows have short horns (recessive trait). What is the dominant allele frequency?

a)

0.25

b)

0.5

c)

0.67

d)

0.75

100.

Widow’s peak hairline in human is determined by a dominant allele. 6400 individuals in a population of 10 000 were found to have widow’s peak hairline. Determine the proportion of the population that is homozygous for the trait. Assume population is at Hardy-Weinberg equilibrium.

a)

6%

b)

16%

c)

36%

d)

60%