WorksheetsJones Derm Exam 3
Total questions: 125
Worksheet time: 1hrs 10mins
Which of the following are functions of the skeletal system?
Protection
Movement
Production of body heat
acid base balance
Blood cell production
What bones form sutures?
Sutural bones
Long bones
Flat bones
What type of bones are used for movement?
flat bones
Long bones
Sutural bones
Which of the following are mature cells, found in the bone matrix (GAP junctions to receive signals)
Osteoblasts
Osteocytes
Osteoclasts
Osteoprogenitor cells
Which of the following are stem cells, which produce osteoblasts and are found in the inner region of bone
Osteocytes
Osteoblasts
Osteoclasts
Osteoprogenitor cells
Which of the following are responsible for resorption/degrading of bone matrix (most active-low Ca2+)
Osteoclasts
Osteoblasts
Osteoprogenitor cells
Osteocytes
Which of the following are immature cells, synthesize new bone (most active-high Ca2+)
Osteocytes
Osteoprogenitor cells
Osteoclasts
Osteoblasts
Which of the following is true regarding compact bone vs spongy bone?
Spongy bone has osteons and are not vascularized, compact bone has no osteons
Spongy bone and compact bone are both composed of osteons, while spongy bone is not vascularized
Spongy bone is not composed of osteons and is not vascularized, compact bone is composed of osteons
spongy bone is not composed of osteons and is vascularized, compact bone is composed of osteons
Which of the following is an incomplete inner layer covering trabecular bone?
Periosteum
Endosteum
Which of the following isolates bone from surrounding tissues, route for blood and nerve entry, connections.
(2 layers)
Endosteum
Periosteum
Located in spongy bone, produces blood cells
Red bone marrow
Yellow bone marrow
Located in bone shaft, adipose tissue for energy source
Red bone marrow
Yellow bone marrow
Which bone growth is categorized as outward bone growth (mediated by osteoclasts and osteoblasts)
Elongation
Appositional
Which of the following is categorized as chondrocytes laying down cartilage which get replaced by osteoid matrix via osteoclasts, and new cartilage gets laid down again?
Elongation
Appositional growth
Which of the following hormones Stimulates bone growth/collagen synthesis?
Cortisol
Estrogen
Growth hormone
Testosterone
Which of the following hormone(s) stimulate osteoblasts and promote ossification, while depleting cartilage and close epiphysial plate?
Estrogen
Growth hormone
Testosterone
Cortisol
Which of the following vitamins Stimulates osteoblast differentiation and are needed for collagen synthesis?
Vitamin A
Vitamin B
Vitamin C
Vitamin K
Which of the following vitamins are Required for osteocalcin (protein secreted by osteoblast)?
Vitamin A
Vitamin B
Vitamin C
Vitamin K
Which of the following can be excreted in feces, absorbed or reabsorbed into soft tissues, absorbed or filtered through the kidneys, and be used to form bones?
Calcium
Phosphate
A decrease in ECF calcium or phosphate will trigger the release of ______?
Estrogen
Cortisol
Parathyroid hormone
Growth hormone
Which of the following will cause the PTH to be inhibited?
Low calcium in ECF
Adequate calcium in ECF
Increase in PTH causes
Decrease in ECF calcium
Increase in ECF calcium
Increase in ECF phosphate
Decrease in ECF phosphate
Increase in calcium causes
Increased calcitriol
increased calcitonin
Decreased calcitonin
PTH stimulates _______ production in the kidney via increasing the synthesis of 1-α hydroxylase.
Calcitriol
Calcitonin
Cortisol
Growth hormone
Which of the following are functions of calcium?
Regulates neural excitability
Role in blood coagulation
Muscle contraction
Fount in ATP
Acid base balance
Decreased calcium in the kidneys will retain ______ calcium ions in our blood and excrete _____ in our urine
More, more
More, less
Less, more
Less, less
PTH and vitamin D receptors of the bone are located on
Osteoclasts
Osteocytes
bone Matrix
Osteoblasts
When PTH and Vitamin D bind to the receptors, they signal the release of
Osteoblasts
RANKL
M-CSF
osteoclasts
proteoclasts bind to to RANKL and M-CSF which will stimulate the differentiation of preosteoclast into an active osteoclast freeing up calcium and vitamin D to enter the blood stream
True
False
High levels of calcium and phosphate activate osteoblasts to build bone.
True
False
Vitamin D deficiency can result in
Osteomyelitis
Osteomalacia
rickets
Osteoporosis
Which of the following is secreted by C-cells of the thyroid gland?
PTH
Calcitriol
Calcitonin
Cortisol
Your patient is experiencing muscle weakness and tetany. After running some labs, you realize that the patients PTH is too low. You believe this is a genetic disease. What is the disease and what would you recommend for treatment?
Hypercalemia, calcium and vitamin D supplementation
Hypocalcemia, calcium and vitamin D restricted diet
Hypercalcemia, calcium and vitamin D restricted diet
Hypocalcemia, calcium and vitamin D supplementation
Your patient is experiencing depression and osteopenia. They also note that they were in the hospital a week ago for kidney stones. You suspect this is a congenital disease. What would the diagnosis be and how would you treat it?
Hypocalcemia, calcium and vitamin D supplementation
Hypercalcemia, calcium and vitamin D supplementation
Hypercalcemia, calcium and vitamin D restricted diet
Osteoporosis, increase calcium, vitamin D, and vitamin K intake, and exercise
Your (60yo) patient tells you that they have shrunk! The physician ordered tests and determined that they have decreased bone density, resulting in a greater risk for fractures. It is determined that the patient has osteoporosis, which of the following would be adequate treatments?
Increase calcium, Vitamin D and Vitamin K intake, and exercise
Estrogen therapy
Calcium and vitamin D restricted diet
Estrogen antagonists
Biophosphonates
Joints serve as the interconnection between 2 bones which allows for range of motion and structure.
True
False
synarthrosis joints are
Slightly moveable
Immovable
Freely moveable
Amphiarthrosis joints are
Immovable
Freely moveable
Slightly moveable
Diarthrosis joints are
Immovable
Slightly moveable
Freely moveable
Which of the following is an immovable joint made when the gap between 2 bones ossifies which forms a single bone.
Bony Joints (synostosis)
Fibrous joints (synarthrodial)
Cartilaginous joints (amphiarthrodial)
Synovial joints (Diarthrodial)
Which of the following has no movement joints with 2 bones liked with cartilage?
Bony Joints (synostosis)
Cartilaginous joints (synarthrodial)
Cartilaginous joints (amphiarthrodial)
Fibrous joints (amphiarthrodial)
Which of the following are freely moving joints at the ends of long bones, and allow for a wide range of movements?
Fibrous joints (amphiarthrodial)
Cartilaginous joints (amphiarthrodial)
Bony Joints (synostosis)
Synovial joints (Diarthrodial)
Which of the following attach the teeth to the jaw via a fibrous collagen ligament?
Sutures
Syndesmoses
Gomphoses
Which of the following are long collagen fibers connecting 2 bones, permits some movement?
Sutures
Syndesmoses
Gomphoses
Which of the following line each bone coming into the joint?
Synovial membrane
Joint capsule
Articular cartilage
Joint cavity
Which of the following consists of an inner synovial membrane and an outer fibrous capsule?
Joint cavity
Joint capsule
Articular cartilage
Bursae
The articular cartilage is made up of (a) cartilage.
Which of the following is the name for the space created between bones and the synovial membrane?
Meniscus
Joint cavity
Joint capsule
Synovial fluid
Synovial fluid is the Interstitial fluid with proteoglycans secreted by cells in the synovial membrane. The synovial fluid helps with:
Lubrication
Shock absorption
Structural support
Nutrient and waste movement
When a joint moves, the _____ move in and cushions the bone.
Ligaments
Tendons
Meniscus
Fat pad
tendons bind muscle to the bone. Which of the following are also functions of the tendons?
Helps hold bone in place
Absorbs force
Reduce friction
Limits the range of motion of a joint
Which of the following attach bone to bone?
Ligaments
Tendons
Bursae
Meniscus
What type of movements are linear movements where 2 opposing surfaces slide past each other?
Angular
Gliding
Flexion
Hyperextension
Which type of movement allows for angle changes, rotation, and circumduction?
Flexion
gliding
Extention
Angular
If a joint can move two ways (I.e. forward and backward, and side to side) it is called:
Multiaxial
Biaxial
Monoaxial
What joint movement is she exhibiting?
Extension
Flexion
Abduction
Rotation
Which joint movement is this?
Flexion
Adduction
Abduction
Extension
Which of the following joint movements does this picture depict?
Abduction
Extension
Adduction
Circumduction
Which of the following joint movements is this?
Circumduction
Abduction
rotation
Adduction
you are looking left when something falls from the bookshelf on your right. As a result you turn your head to the right. This is an example of:
Circumduction
Adduction
Rotation
Abduction
Your elbow, jaw and knee are examples of what kind of joint?
hinge
Ball-and-socket
Condylar
Ellipsoid
Saddle
Your shoulder and hip are an example of what kind of joint?
Hinge
Ball-and-socket
Condylar
Pivot
Your patient comes in with inflammation of the bursae. Which of the following could have caused their bursitis?
Friction due to repetitive movement
Pressure
Chemical irritation
Too much exercise
Infection in the joint
Your patient was diagnosed with bursitis, which of the following would be considered a treatment?
Surgical removal of bursae
Injections
Antihistamine
Anti inflammatory
Antibiotic
Your patient complains of pain in their face, clicking sounds when moving their jaw, and radiating headaches. In addition, they are experiencing limited movement, making it hard to eat certain foods. This patient has TMJ. What are appropriate treatments?
Anti inflammatory drug
Physical Therapy
Psych therapy
Soft foods
Splints
Arthritis ALWAYS involves damage to the articular cartilage.
True
False
What type of arthritis causes aging joints, damage to cartilage, (age over 60) leading to exposed bones, causing bone spurs, restricted movement and pain?
Rheumatic Arthritis
Osteoarthritis
Gouty arthritis
What type of arthritis results from the immune system attacking joint tissue?
Osteoarthritis
Rheumatic arthritis
Gouty arthritis
What type of arthritis occurs due to accumulation of uric acid crystals in the joints?
Osteoarthritis
Rheumatic arthritis
Gouty arthritis
Which of the following are treatments for arthritis?
Physical Therapy
Antibiotics
anti inflammatories
Surgery
Which of the following events will occur when calcium levels are high in the blood?
Calcium sensing receptors are activated
Parathyroid hormone secretion increases
Neural hyperexcitability
Muscle weakness
Active vitamin D levels increase
Which of the following is a cell stimulated by PTH?
Osteoclast
Osteocyte
Osteoblast
Which of the following is a mature bone cell embedded in the bone matrix?
Osteoclast?
Osteoblast
Osteocyte
With a decrease in plasma calcium, the calcium receptor on the parathyroid gland in binds calcium which releases PTH and decreases active vitamin D.
True
False
Place them in the correct order.
1. C-cells of the thyroid gland secrete calcitonin
2. osteoclast activity is inhibited
3. Bone deposition increases
4. plasma calcium increases
1, 4, 2, 3
4, 1, 2, 3
3, 1, 2, 4
4, 2, 1, 3
The cartilage joint between the diaphysis and the epiphysis is
Moveable
Immovable
The hip joint is
Moveable
Immovable
Which of the following is a hinge joint with olecranon?
Jaw
Shoulder
Knee
Elbow
Which of the following contains the posterior and anterior cruciate ligaments?
Hip
Knee
Shoulder
Jaw
Trabeculae are structural characteristics of compact bone.
True
False
A femur includes both compact and spongy bone tissues.
True
False
Most bones develop from hyaline cartilage.
True
False
The growth zone of the long bones of adolescents is the articular cartilage.
True
False
Osteoclasts develop from osteoblasts.
True
False
Osteocytes develop from osteoblasts.
True
False
The protein of the bone matrix is called hydroxyapatite.
True
False
Blood vessels travel through the central canals of compact bone.
True
False
Vitamin D promotes bone deposition, not resorption.
True
False
Parathyroid hormone promotes bone resorption and raises blood calcium concentration.
True
False
Synovial joints are also known as synarthroses.
True
False
The femur is held tightly in the acetabulum mainly by the round ligament.
True
False
Unlike most ligaments, the periodontal ligaments do not attach one bone to another.
True
False
synovial fluid is secreted by the synovial membrane of the joint capsule and fills the bursae.
True
False
1. Calcium is required for all of the following except __________.
Nerve conduction
Blood clotting
Muscle contraction
All of these require calcium
Which of the following mineral gives bone it's rigid structure?
Calcium
Phosphate
Collagen
Hydroxyapatite
Bones are made up of which of the following three tissue types?
Spongy bone and trabecular bone
Spongy bone, fat, and bone marrow
Compact bone, spongy bone, and bone marrow
Compact bone, white marrow and red marrow
Bones are made up of which of the following three tissue types?
Spongy bone and trabecular bone
Spongy bone, fat, and bone marrow
Compact bone, spongy bone, and bone marrow
Compact bone, white marrow and red marrow
Which of the following is the term for the functional unit of compact bone?
Haversian canal
Trabeculae
Osteon
Lamellae
Which of the following cells is responsible for depositing hydroxyapatite into bone matrix?
Osteocytes
Myelocytes
Osteoclasts
Osteoblasts
Melanocytes
In regards to bone marrow, "red marrow" is primarily made up of ___________ cells, while "yellow marrow" is primarily made up of ___________ cells.
Active, dormant
Erythrocytic, leukocytic
Hematopoietic, fat
Proliferating, calcified
1. The length of long bones is increased via the hypertrophy and eventual apoptosis of chondrocytes which leave cavities that are then colonized by osteoprogenitor cells. This process is referred to as __________.
Osteoblast mineralization
Endochondrial mineralization
Apoptotic ossification
Endochondrial ossification
Muscle is attached to the periosteum of bone via which of the following?
Articular cartilage
Ligaments
Tendons
Sutures
Which of the following tissues is not part of a bone as an organ?
Dense connective
Cartilage
Muscle
Blood
The organic matter of living bone includes
Calcium phosphate
Collagen fibers and cells
Calcium carbonate
Magnesium and fluoride
The _______ is an example of a sesamoid bone.
Vertebra
Femur
Carpal
Patella
The epiphyseal plate represents the
Ends of the epiphyses
Shaft between the epiphyses
Growth zone of hyaline cartilage
Membrane around bone
The central canal of a bone osteon contains
Blood vessels and nerves
Osteocytes
Red bone marrow
Yellow bone marrow
Internal and external rotation of the humerus are made possible by which joint?
Pivot
Condylar
Ball-and-socket
Saddle
Hinge
Which of the following is the least movable?
A diarthrosis
A synostosis
A symphysis
A synovial joint
A condylar joint
Which of the following joints has anterior and posterior cruciate ligaments?
Shoulder
Elbow
Hip
Knee
Ankle
Which cells have a ruffled border and secrete hydrochloric acid?
C-cells
Osteocytes
Osteogenic cells
Osteoblasts
Osteoclasts
The marrow cavity of an adult bone may contain
Myeloid tissue (blood tissue)
Hyaline cartilage
Periosteum
Osteocytes
Articular cartilages
The spurt of growth in puberty results from cell proliferation and hypertrophy in the
Epiphysis
Epiphyseal line
Compact bone
Epiphyseal plate
Spongy bone
Osteoclasts are most closely related, by common descent, to
Osteoprogenitor cells
Osteogenic cells
Blood cells
Macrophage
Osteoblasts
Which of these is not an effect of PTH?
Rise in blood phosphate level
Reduction of calcium excretion
Increased intestinal calcium absorption
Increased number of osteoclasts
Increased calcitriol synthesis
One long bone meets another at its
Diaphysis
epiphyseal plate
Periosteum
Metaphysis
Epiphysis
Calcitriol is made from
Calcitonin
7-dehydrocholesterol
Hydroxyapatite
Estrogen
PTH
what is the function of calcitonin?
Increased calcium levels
Inhibition of osteoblast
Decreases calcium levels
Inhibits osteoclasts
Which of these could result from hyperparathyroidism?
increased bone deposition
Fractures
Convulsions
All of the above
The lubricant of diarthrosis is called (a)
A fluid filled sac that eases the movement of a tendon over a bone is called a/an
(a)
The joint between a tooth and mandible is called a/an
(a)
In a (a) suture, the articulate bones have interlocking wavy margins, somewhat like a dovetail joint in carpentry.
While kicking a football, what type of action does the knee joint exhibit?
(a)
The menisci of the knee are functionally similar to the (a) of the temporomandibular joint.
