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Gastrointestinal Drugs

Total questions: 120

Worksheet time: 1hrs 7mins

Name
Class
Date
1.
Region where chyme enters the small intestine is known as ______________.
a)
colon
b)
ileum
c)
jejunum
d)
duodenum
2.
This enzyme digests fats (lipids)
a)
Protease
b)
Carbohydrase
c)
Lipase
d)
Bile
3.
Bile is made by which digestive organ?
a)
Gallbladder
b)
Stomach
c)
Rectum
d)
Liver
4.
Nutrients from digested food are absorbed in which digestive organ?
a)
Small Intestine
b)
Stomach
c)
Large Intestine
d)
Gallbladder
5.
Number 5 is pointing to the...
a)
Liver
b)
Gallbladder
c)
Pancreas
d)
Stomach
6.
Which organ pushes food down to the stomach?
a)
Mouth
b)
Esophagus
c)
Rectum
d)
Large intestine
7.
As waste moves through the digestive system, the ______ absorbs water before storing waste in the rectum.
a)
Small intestine
b)
Stomach
c)
Esophagus
d)
Large intestine
8.
Bile is stored in which secondary digestive organ?
a)
Stomach
b)
Liver
c)
Gallbladder
d)
Pancreas
9.
What does mucus do?
a)
Digests food in the mouth.
b)
Digests food in the stomach
c)
Protects the stomach from digesting iteself
d)
Absorbs nutrients from food so the body has energy.
10.
What digestive enzyme that is found in the stomach and begins the digestion of proteins?
a)
Amylase
b)
Pepsin
c)
Lipase
d)
Rennin
11.
What separates the esophagus from the stomach?
a)
villi
b)
pyloric sphincter
c)
rugae
d)
cardiac sphincter
12.
Where are the α and β cells in the pancreas located?
a)
Islets of Langerhans
b)
Acini
c)
Ducts
d)
Hepatic cords
13.
The green part is the 
a)
rugae
b)
pyloric sphincter
c)
cardioesophageal sphincter
d)
stomach
14.

what will happen when glucose concentration in your blood getting high?

a)

Beta cell secrete glucagon and make you high

b)

Beta cell secrete insulin and promotes movement of glucose into certain cells

c)

alpha cell secrete glucagon and help your blood circulation

d)

alpha cell secrete insulin and give you energy

15.

Parts of the small intestine after the duodenum is known as

a)

Jejunum

b)

Lipase duodenum

c)

Amylase duodenum

d)

Lipase ileum

16.

Numerous fingerlike projections in the folds of the wall of the ileum is classified as

a)

Bolus

b)

Chyme

c)

Bile

d)

Villi

17.

Which part of the small intestine joins the large intestine?

a)

Ileum

b)

Duodenum

c)

Jejunum

18.

Rhythmic muscular contractions that move food along the GI tract

a)

heterotrophs

b)

peristalsis

c)

nutrients

d)

alimentary canal

19.

Muscular organ that churns and mashes food into chyme

a)

Saliva

b)

Tonuge

c)

Esophagus

d)

Stomach

20.

Which enzymes does the pancreas pump out? (3 answers)

a)

Amylase

b)

Protease

c)

Lipase

d)

Bile

21.

reduce bronchospasm

a)

antibiotics

b)

anticholinergics

c)

anticonvulsants

d)

antiemetics

22.

Which of the following is not a common cause of peptic ulcer disease (PUD)?

a)

. Chronic alcohol ingestion

b)

Nonsteroidal antiinflammatory drugs (NSAIDs)

c)

Stress-related mucosal damage

d)

Helicobacter pylori infection

23.

Which of the following is a complication of PUD?

a)

. GI bleeding

b)

Perforation

c)

Obstruction

d)

All of the above

24.

Which of the following is an independent risk factor for the development of NSAID-induced peptic ulcers?

a)

Concomitant use of corticosteroids

b)

Alcohol consumption

c)

Concomitant use of selective serotonin receptor inhibitors (SSRIs

d)

Smoking

25.

Gastric acid secretion is under the control of the following agents EXCEPT:

a)

) Histamine

b)

Acetylcholine

c)

Gastrin

d)

Serotonin

26.

Indicate the drug belonging to M1-cholinoblockers:

a)

Cimetidine

b)

Ranitidine

c)

Pirenzepin

d)

Omeprazole

27.

Indicate the laxative drug belonging to osmotic laxatives:

a)

Docusate sodium

b)

Bisacodyl

c)

Phenolphthalein

d)

Sodium phosphate

28.

Which of the following purgatives undergoes enterohepatic circulation to produce prolonged action:

a)

Docusates

b)

Castor oil

c)

Mag. sulfate

d)

Phenolphthalein

29.

The following laxative lowers blood ammonia level in hepatic encephalopathy:

a)

Bisacodyl

b)

Liquid paraffin

c)

Magnesium sulfate

d)

Lactulose

30.

The most suitable laxative for a patient of irritable bowel disease with spastic constipation is:

a)

Liquid paraffin

b)

Bisacodyl

c)

Senna

d)

Dietary fibre

31.

Stimulant purgatives are contraindicated in the following:

a)

Bed ridden patients

b)

Before abdominal radiography

c)

Atonic constipation

d)

Spastic constipation

32.

Dextromethorphan is an:

a)

Analgesic

b)

Antitussive

c)

Expectorant

d)

Antihistaminic

33.

Sodium cromoglycate has a role in the treatment of the following conditions except

a)

Chronic bronchial asthma

b)

Chronic urticaria

c)

Chronic allergic rhinitis

d)

Chronic allergic conjunctivitis

34.

Gastric acid secretion is under the control of the following agents EXCEPT:

a)

Histamine

b)

Acetylcholine

c)

Serotonin

d)

Gastrin

35.

Tick the drug forming a physical barrier to HCL and Pepsin:

a)

Ranitidine

b)

Sucralfate

c)

Omeprazole

d)

Pirenzepine

36.

Select the drug which inhibits peristalsis

a)

Castor oil

b)

Bisacodyl

c)

Loperamide

d)

Sorbitol

37.

Indicate the side effect of Theophylline:

a)

Bradycardia

b)

Increased myocardial demands for oxygen

c)

Depression of respiratory centre

d)

Elevation of the arterial blood pressure

38.

Codeine is used clinically as:

a)

Analgesic

b)

Antitussive

c)

Antidiarrhoeal

d)

All of the above

39.

Select the fastest acting inhaled bronchodilator:

a)

Ipratropium bromide

b)

Formoterol

c)

Salbutamol

d)

Salmeterol

40.

The most dependable emetic used to expel ingested

poisons is:

a)

Intramuscular emetine

b)

Oral syrup ipecacuanha

c)

Intramuscular apomorphine

d)

Oral bromocriptine

41.

In case of hill journey, antimotion sickness drugs are

best administered at:

a)

Twelve hours before commencing journey

b)

One hour before commencing journey

c)

Immediately after commencing journey

d)

At the first feeling of motion sickness

42.

Which of the following classifications of medications can be used as a calcium supplement?

a)

Antidiarrhea

b)

Antacid

c)

Antinausea

d)

PPI's

43.

Which of the following is NOT an antidiarrheal?

a)

Pectin

b)

Diphenoxylate

c)

Pepcid

d)

Immodium

44.

What is used to prevent travelers diarrhea?

a)

Pepcid

b)

Amoxicillin

c)

—Bismuth subsalicylate

d)

Tums

45.

Which of the following is a cytoprotective agent?

a)

Advil

b)

Cytotec

c)

Pepcid

d)

Tums

46.

Which of the following is NOT an antiemetic

a)

Antihistamine

b)

Cannabinoid

c)

5-HT3 Receptor Antagonists

d)

Tums

47.

Can PPI's be used in infants?

a)

Yes

b)

No

c)

Only certain PPI's

48.

What does triple therapy treat?

a)

PUD

b)

GERD

c)

IBS

d)

Diverticulitis

49.

Pernicious anemia is when your blood is lacking?

a)

Iron

b)

Vitamin B12

c)

Folate

d)

Vitamin d

50.

In a patient with a history of gastric bypass. Vitamin b12 should be given by what route?

a)

IV

b)

PO

c)

SL

d)

Any way

51.

What is the main function of the digestive system?

a)

Provides fuel that keeps cells functioning

b)

Makes the person feel full from eating

c)

To break down food into smaller pieces

d)

To consume food

52.

Whats the function of the tongue?

a)

To lick the food

b)

Roll food into bolus

c)

To lubricate the food and mouth

d)

To impress people with your weird tongue

53.
Bile is made by which digestive organ?
a)
Gallbladder
b)
Stomach
c)
Rectum
d)
Liver
54.

After Bile is produced in the liver,where is it stored?

a)

Stomach

b)

Liver

c)

Gallbladder

d)

Pancreas

55.
Nutrients from digested food are absorbed in which digestive organ?
a)
Small Intestine
b)
Stomach
c)
Large Intestine
d)
Gallbladder
56.

Number 4 is pointing to the....

a)

Anus

b)

Rectum

c)

Large Intestine

d)

Small intestine

57.
Number 5 is pointing to the...
a)
Liver
b)
Gallbladder
c)
Pancreas
d)
Stomach
58.
Number 3 is pointing to the...
a)
Small intestine
b)
Rectum
c)
Large intestine
d)
Stomach
59.
Number 2 is pointing to the...
a)
Esophagus
b)
Stomach
c)
Small intestine
d)
Anus
60.

A digestive enzyme that is found in the stomach and mostly digests proteins

a)

Peptides

b)

Amylase

c)

Pepsin

d)

Bile

61.

Which is NOT a function of the Digestive System

a)

To pass out waste products out of the body

b)

Digest food for energy and growth

c)

Break down nutrients from food

d)

Pump blood around the body

62.

What is the path of the digestive system??

a)

Mouth,Pharynx,Esophagus,Stomach,Small Intestine,Large Intestines,Rectum,Anus

b)

Mouth,Esophagus,Stomach,Small Intestine,Large intestine,Rectum,Anus

c)

Anus,Esophagus,Stomach,Small Intestine,Large Intestine,Rectum,Anus

d)

Mouth,Esophagus,Stomach,Small Intestines,Large Intestines,Rectum,Anus

63.

I am the longest organ in your body,I absorb most water and nutrients.What am I?

a)

Small Intestine

b)

Small Intestines

c)

Esophagus

d)

Large Intestine

64.

What is the order of the small intestine?

a)

Ileum,Jejunum,Duodenum

b)

Duodenum,Jejunum,Ileum

c)

Jejunum,Ileum,Duodenum

d)

Duodenum,Ileum,Jejunum

65.

The chewing and grinding of food into smaller pieces is an example of...

a)

Mechanical process

b)

Chemical Digestion

c)

Physical Digestion

d)

Ingestion

66.

What are the stimuli for GIT hormones secretion (select more than one answer)

a)

Distension

b)

Chyme Osmolarity

c)

Chyme acidity

d)

Chyme concentration

67.

What are types of receptors available in GIT

a)

Mechanoreceptor

b)

Osmoreceptor

c)

Chemoreceptor

d)

All of the above

68.

What are the effectors after getting stimulates by hormones?

a)

Muscle in the GIt walls

b)

secretion of the exocrine glands

c)

Both of the above

d)

None of the above

69.

What is/are the phase of GI control?

a)

Cephalic

b)

Gastric

c)

Intestinal

d)

All of the above

70.

Which statements are correct?

a)

Submucosal plexus stimulates circular and longitudinal muscle

b)

Myenteric plexus stimulates circular and longitudinal muscle

c)

Submucosal plexus stimulates villi movement

d)

Myenteric plexus stimulates villi movement

71.

Gastrin family of hormones are (select more than one question)

a)

Gastrin

b)

CCK

c)

Secretin

d)

glucagon

72.

Gastrin is secreted at

a)

Buccal cavity

b)

Esophagus

c)

Intestine

d)

Stomach

73.

Gastrin stimulates the secretion of

a)

Acid

b)

carboxypeptidase

c)

trypsin

d)

chymotrypsin

74.

Enzyme responsible for formation of acid by combining water and carbon di oxide

a)

Amylase

b)

galactosidase

c)

carbonic anhydrase

d)

peptidyl transferase

75.

Which one inhibit the acid secretion

a)

Gastrin

b)

Histamine

c)

Acetylcholine

d)

Somatostatin

76.

How big is big gastrin (hint: Big-big, big, gastrin, gastrin-IV)

a)

95

b)

34

c)

17

d)

14

77.

which one is conserved amino acid in gastrin and CCK?

a)

Pentagastrin

b)

Octagastrin

c)

Heptagastrin

d)

trigastrin

78.

What are the stimulus for gastrin secretion?

a)

peptide and amino acid

b)

distension

c)

both of the above

d)

none of the above

79.

what are the overall functions of gastrin? (select more than one option)

a)

Stimulate Gastric Acid and pepsin secretion

b)

Growth of gastric mucosa and intestinal mucosa

c)

Stimulate Gastric Motility

d)

Contraction of muscle at gastro esophageal junction cardiac sphincter prevents reflux

80.

which statement is/are correct?

a)

Acetylcholine act by cAMP pathway

b)

Gastrin act by cAMP pathway

c)

Hitamine act by PIP2 pathway

d)

Histamine act by cAMP pathway

81.

Which of the following organs performs mechanical digestion?

a)

Small intestine

b)

Large intestine

c)

Stomach

d)

Esophagus

e)

Liver

82.

What is the soft palate made of?

a)

Bone

b)

Muscle

c)

Glands

d)

Fatty tissue

83.

Where does the digestion of carbohydrates begin?

a)

Mouth

b)

Stomach

c)

Small intestine

d)

Pancreas

84.

Structure that prevents food from going into the respiratory tract when we swallow

a)

Soft palate

b)

Epiglottis

c)

Glottis

d)

Oropharynx

85.

Rhythmic contraction of smooth muscle that moves food forwards in the gastrointestinal tract

a)

Peristalsis

b)

Chyme

c)

Pylorus

d)

Amylase

86.

What substance activates pepsinogen?

a)

Mucus

b)

Bile

c)

Hydrochloric acid

d)

Bicarbonate

87.

Where in the gastrointestinal tract does the secretions from the accessory glands enter?

a)

Duodenum

b)

Jejunum

c)

Ileum

d)

Colon

e)

Pancreas

88.

What is the function of bile?

a)

Emulsifying lipids

b)

Emulsifying amino acids

c)

Protection against infection

d)

Increases surface area to increase absorption of nutrients

89.

What is the treatment for the main cause of gastritis?

a)

Surgery to cut the nerves of the stomach

b)

Antibiotics

c)

Immunosuppressant drugs

d)

Milk

90.

What is the endocrine secretion of the pancreas?

a)

Insulin

b)

Bicarbonate

c)

Trypsin

d)

Amylase

91.

The use of proton pump inhibitors and H2 blockers in older adults has been associated with decreased absorption of vitamin B12.

a)

True

b)

False

92.

H2 receptor antagonists is the most suitable agent to treat GERD in cardiac arrhythmic patients.

a)

True

b)

False

93.

Ranitidine has the most significant effect in slowing down the metabolism of other drugs involved in CYP450 metabolism pathway.

a)

True

b)

False

94.

The use of cimetidine is often associated with enlargement or swelling of breast tissue in males.

a)

True

b)

False

95.

The choice of antacid depends on adverse effect and absorption factors.

a)

True

b)

False

96.

Magnesium hydroxide and aluminium hydroxide antacids have a tendency to cause metabolic alkalosis.

a)

True

b)

False

97.

Aluminium hydroxide antacid causes diarrhea whereas magnesium hydroxide antacid increases the risks of constipation.

a)

True

b)

False

98.

Calcium carbonate should be taken with meals, since acidity improves absorption.

a)

True

b)

False

99.

Aluminium hydroxide has a slower effect in neutralizing HCl in the stomach compared to other antacids.

a)

True

b)

False

100.

Antacids can be administered with other drugs concurrently.

a)

True

b)

False

101.

Ranitidine inhibits binding of histamine released by parietal cells to H2 receptor on enterochromaffin-like cells in the gastric mucosa lining.

a)

True

b)

False

102.

PPIs are generally having excellent safety and efficacy profiles for treating acid-peptic disorders in children.

a)

True

b)

False

103.

Similarly to the antacids, the PPIs tablets are chewed and swallowed before meals to ensure the therapeutic effectiveness of the drug.

a)

True

b)

False

104.

Omeprazole can be administered on empty stomach or 30 minutes before meals for better acid suppression effect in the stomach.

a)

True

b)

False

105.

Not all proton pumps are inhibited upon initiation of PPIs. It requires 3-4 days of daily medication for full acid-inhibiting action. After stopping the drug, it takes 3-4 days for full acid secretion to return.

a)

True

b)

False

106.

Combination of aluminium hydroxide and sucralfate will increase the risk of aluminium toxicity.

a)

True

b)

False

107.

The only histamine-2 antagonist approved for use in younger children (1-16 years old) is

a)

cimetidine.

b)

ranitidine.

c)

famotidine.

d)

nizatidine.

108.

Which drugs below may be the best choice for treating GERD in older patients due to its better therapeutic efficacy and fewer side effects?

a)

Cimetidine

b)

Omeprazole

c)

Sodium bicarbonate

d)

Sucralfate

109.

Which H2 receptor antagonist is excreted in the urine with minimal first-pass metabolism in the liver?

a)

Cimetidine

b)

Ranitidine

c)

Famotidine

d)

Nizatidine

110.

Which of the following antacids does not interfere absorption of other drugs in the gut lumen?

a)

Sodium bicarbonate

b)

Calcium carbonate

c)

Aluminium hydroxide

d)

Magnesium hydroxide

111.

Prolonged used of aluminium hydroxide results in _________ depletion.

a)

chloride

b)

phosphate

c)

calcium

d)

sulphate

112.

Besides aluminium hydroxide, which of the following antacids can cause constipation?

a)

Magnesium hydroxide

b)

Calcium carbonate

c)

Sodium carbonate

d)

Magnesium chloride

113.

Excessive consumption of antacid X results in cardiac disturbances and nerve damage, leading to fatality. X is

a)

Sodium bicarbonate

b)

Calcium carbonate

c)

Aluminium hydroxide

d)

Magnesium hydroxide

114.

Omeprazole lowers gastric acid concentration by

a)

inhibiting the muscarinic receptor on ECL cells.

b)

neutralizing the HCL.

c)

blocking the H2 receptor on parietal cells.

d)

inhibiting H+,K+-ATPase enzyme system on parietal cells.

115.

Which of the following proton pump inhibitors has a rapid onset of action and faster elimination?

a)

Esomeprazole

b)

Omeprazole

c)

Lansoprazole

d)

Pantoprazole

116.

PPIs are superior than H2 receptor antagonists in inhibiting gastric HCL secretion due to these factors EXCEPT

a)

PPIs able to maintain intragastric pH >4 for between 15 - 21 hours daily (vs 8 hours for H2 receptor antagonists).

b)

able to control postprandial and nocturnal intragastric pH.

c)

long-term usage of PPIs doesn’t require dose escalation.

d)

cheaper and easily accessible.

117.

Which of the following drugs is effective in combating Helicobacter pylori infection upon combination with antibiotics?

a)

Proton pump inhibitors

b)

H2 receptor antagonists

c)

Antacids

d)

Mucoprotectant

118.

Which of the following drugs is not involved in the treatment of GERD?

a)

Magnesium trisilicate

b)

Pantoprazole

c)

Ranitidine

d)

Misoprostol

119.

Triple regimen for eradicating H. pylori infection include these antibiotics EXCEPT

a)

Clarithromycin

b)

Amoxycillin

c)

Tetracycline

d)

Metronidazole

120.

Drug X acts by forming an ulcer-adherent complex at the ulcer site, protecting the ulcer from acid, bile salts and pepsin, and at the same time promoting healing of the ulcer. Drug X refers to

a)

misoprostol.

b)

sucralfate.

c)

alumnium hydroxide.

d)

cimetidine.

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