WorksheetsNephrology exam 1 : Rapid Review Dr. Jones
Total questions: 55
Worksheet time: 3hrs 45mins
The main function of the kidneys is the regulation of the intracellular fluid.
True
False
Blood pressure is regulated through the actions of the kidneys.
True
False
Dilation of the afferent arteriole would increase glomerular pressure.
True
False
A decrease in blood pressure will cause an increase in GFR through sympathetic stimulation
False
True
The proximal convoluted tubule reabsorbs approximately 65% of water and ions salt entering it.
True
False
Since water follows the reabsorption of Na+ in the proximal tubule, the filtrate is isosmotic with the blood.
True
False
As the tubular filtrate moves through the descending limb of the loop of Henle, the osmolality of the filtrate increases
True
False
The collecting duct is naturally impermeable to salt but permeable to water.
True
False
The maximal response to antidiuretic hormone occurs in the cortical nephrons
True
False
Inulin clearance gives a measurement of the glomerular filtration rate.
True
False
The renal plasma clearance of a substance that is filtered and reabsorbed must be less than the GFR.
True
False
Only about 20% of renal blood is filtered in one pass through the
True
False
Increased aldosterone secretion stimulates renal potassium retention
True
False
In response to low blood plasma Na+, reduced ADH will decrease water volume in the blood to match lower Na+ concentration while increased aldosterone will increase Na+ reabsorption to match the higher water volume of blood.
True
False
What structures carry urine from the kidneys to the urinary bladder?
ureters
urethras
calyces
pyramids
The __________ is a capillary network that produces a blood filtrate that enters the urinary tubules.
vasa recta
peritubular capillary
glomerulus
interlobar capillary
The _______________ nephrons play an important role in producing concentrated urine.
juxtamedullary
cortical
pelvic
calical
The efferent arteriole delivers blood to the _______________ (choose all that apply)
peritubular capillaries
vasa recta
glomerulus
juxtaglomerular apparatus
The renal pelvis receives urine from the
minor calyces
ureters
renal pyramids
major calyces
The __________ is the functional unit of the kidney.
calyx
nephron
neuron
medulla
The average glomerular filtration rate is equal to
180 L/day
5.5 l/min
180ml/day
100 mmHg/hour
Increased sympathetic neuron activity will cause
vasoconstriction of afferent arterioles
increased GFR
increased urine production
decreased blood volume
The ability of the kidneys to maintain a relatively constant GFR despite fluctuating blood pressures is called
renal plasma threshold
renal transport maximum
renal plasma clearance
renal autoregulation
Systemic hypotension would induce __________ of afferent arterioles.
constriction
dilation
no change
The sensor in tubule glomerular feedback is a group of cells called the
macula densa
gomerulus
vasa recta
macula lutea
Glomerular filtration would be decreased by (choose all that apply)
increased plasma protein concentration. (this does not change very often, but it does increase near the end of the glomerulus)
increased glomerular filtrate protein concentration.
decreased glomerular hydrostatic pressure.
increased mean arterial pressure.
Through renal autoregulation, an increase in blood pressure will cause the afferent arteriole to ____ and therefore the GFR will ____. A. dilate, not change.
dilate, not change
dilate, decrease
constrict, decrease
constrict, no change
The return of molecules from the tubules to the blood is called
reabsorption
secretion
filtration
autoregulation
The majority of reabsorption occurs in the
collecting duct
distal convoluted tubule
loop of henle
proximal convoluted tubule
Na+ reabsorption is a(n) __________ process, while Cl- reabsorption is a(n) __________ process
active, active
active, passive
passive, passive
passive, active
The ____ limb of the loop of Henle is impermeable to salt
ascending
descending
both limbs
neither limb
Which of the following is the correct order of the nephron tubule structures?
distal convoluted tubule, loop of Henle, proximal convoluted tubule, Bowman's capsule
proximal convoluted tubule, Bowman's capsule, distal convoluted tubule, loop of Henle
Bowman's capsule, proximal convoluted tubule, loop of Henle, distal convoluted tubule
loop of Henle, Bowman's capsule, proximal convoluted tubule, distal convoluted tubule
Which of the following is NOT a potential filtration barrier in the glomerular capsule?
glomerular basement membrane
capillary fenestrae
parietal layer of the capsule
slit diaphragm
The primary filter to exclude proteins from the filtrate is the
glomerular basement membrane
capillary fenestrae
parietal layer of the capsule
slit diaphragm
What is the order that filtrate must pass through to the glomerular capsule?
podocytes of glomerular epithelium, glomerular basement membrane, capillary fenestrae
capillary fenestrae, glomerular basement membrane, podocytes of visceral glomerular epithelium
glomerular basement membrane, capillary fenestrae, podocytes of visceral glomerular epithelium
capillary fenestrae, podocytes of visceral glomerular epithelium, glomerular basement membrane
The tubular filtrate osmolarity __________ as it flows through the ascending limb of the loop of Henle.
increases
decreases
remains unchanged
The concentration of renal filtrate is highest in the
proximal convoluted tubule
base of the loop of Henle
distal convoluted tubule
cortical portion of the collecting duct
Countercurrent multiplication occurs by the actions of the
vasa recta
peritubular capillaries
loop of Henle
_________ is a non salt molecule that contributes to the hypertonicity of the interstitial fluid of the renal tubules.
Urea
Protein
Creatinine
Xenobiotic molecule
Antidiuretic hormone:
stimulates water reabsorption by the kidney.
induces fusion of aquaporin containing vesicles with the plasma membrane.
is secreted in response to dehydration.
The movement of molecules and ions from the peritubular capillaries into interstitial fluid and then into the nephron tubule is called
secretion
reabsorption
excretion
filtration
If the rate of urine formation is 2 ml/min, the urine inulin concentration is 25 mg/ml, and the plasma inulin concentration 0.5 mg/ml, then the GFR is
0.04 ml/min
100 ml/min
6.25 ml/min
Decreased glomerular filtration rate would
increase plasma protein clearance rate
increase plasma urea clearance rate
decrease plasma creatinine clearance rate
decrease plasma glucose clearance rate
The renal plasma clearance of a substance that is filtered but not reabsorbed or secreted is ___ the GFR.
greater than
less than
equal to
The _________________ is the saturation point of renal carrier molecules.
transport maximum
GFR
renal plasma clearance
renal plasma treshold
Excessive aldosterone secretion would induce
decrease plasma potassium
decrease plasma sodium
decrease plasma chloride
no change un plasma ion balance
Diuretics
decrease urine production
induce hypertension
often act on the proximal convoluted tubule
often act on the distal convoluted tubule
The main region of aldosterone action is the
distal convoluted tubule
proximal convoluted tubule
medullary collecting duct
cortical collecting duct
Granular cells of the juxtaglomerular apparatus respond to decreased blood volume and increased sympathetic nerve activity by secreting
renin
inulin
angiotensinogen
natriuretic hormone
Angiotensin-converting enzyme is mostly present in the capillaries of the
liver
kidneys
lungs
adrenal medulla
The presence of renin secreting tumors may cause
hypertension
increase aldosterone secretion
increased renal sodium reabsorption
Hemorrhage would induce
increased renin secretion
increased atrial natriuretic peptide secretion
decreased ADH secretion
Aldosterone secretion from the adrenal cortex is stimulated by a(n) ____ in blood Na+ or a(n) ___ in blood K+.
increase, decrease
increase, increase
decrease, increase
decrease, decrease
Spironolactone
inhibits the actions of aldosterone
blocks bicarbonate reabsorption
stimulates hypertension
activates NA+/K+ pumps
Loop diuretics such as Lasix
inhibit the action of ADH
add extra solutes to the filtrate
inhibit active transport of salt out of the ascending loop of Henle limb
inhibit salt transport in the first section of the distal tubule.
