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PCOG - ALL FINALS HANDOUT (PART 1)

Total questions: 85

Worksheet time: 43mins

Name
Class
Date
1.

Which of the following is/are true about purine alkaloids?

I. 6-membered pyrimidine ring fused to the 5-membered imidazole ring

II. Derived from xanthine

III. Derived from tryptophan

IV. Also called xanthine alkaloids

a)

I, II and IV only

b)

I and II only

c)

II and IV only

2.

Quaternary Structure is an arrangement of the subunits of a protein that has more than one polypeptide chain.

a)

True

b)

False

3.

In the blood plasma, FIBRINOLYSIN and streptokinase convert plasminogen to plasmin.

a)

True

b)

False

4.

Nutmeg

a)

Hallucinogen

b)

Rodenticide

c)

Insecticide

d)

Allergen

e)

Teratogen

5.

Red squill

a)

Hallucinogen

b)

Rodenticide

c)

Insecticide

d)

Allergen

e)

Teratogen

6.

Pyrethrum

a)

Hallucinogen

b)

Rodenticide

c)

Insecticide

d)

Allergen

e)

Teratogen

7.

Pollen

a)

Hallucinogen

b)

Rodenticide

c)

Insecticide

d)

Allergen

e)

Teratogen

8.

Lupin

a)

Hallucinogen

b)

Rodenticide

c)

Insecticide

d)

Allergen

e)

Teratogen

9.

Arecoline from "nga-nga" is a derivative of nicotinic acid.

a)

True

b)

False

10.

Papaveraceae is a family rich in alkaloids.

a)

True

b)

False

11.

The hypotensive and anxiolytic drug, Reserpine, is from SNAKEROOT or Rauwolfia serpentina.

a)

True

b)

False

12.

Which of the following is/are true about Ephedra?

I. Ephedra sinica

II. Also called ma huang

III. An alkaloidal amine

IV. Contains ephedrine which is found in in Lianhua Qingwen

a)

I and II only

b)

None of these

c)

All of these

d)

II and IV only

13.

Lobeline and coniine are derivatives of pyrrolidine.

a)

True

b)

False

14.

Hypericin, an anti – depressant substance, is obtained from ____:

a)

St. John’s wort

b)

Neem tree

c)

Karela

15.

An alkaloid used as anti–asthma and is also called jimson weed:

I. Jamestown weed

II. Stramonium

III. Coca

a)

I and II only

b)

I and III only

c)

I, II and III only

16.

Synonym of marijuana:

a)

Atropa

b)

Indian hemp

c)

Indian tobacco

d)

Pituri

17.

The following tropane alkaloids belong to the Solanaceae family, EXCEPT:

a)

Scopolamine

b)

Cocaine

c)

Henbane

d)

Atropine

18.

Hypersecretion of ADH leads to SIADH (Symptom of Inappropiate Anti- Diuretic Hormone).

a)

True

b)

False

19.

It is formed by methylation of morphine:

a)

Heroin

b)

Codeine

c)

Morphine

d)

Hydrocodone

20.

The following are synonyms of vitamin B9, EXCEPT:

a)

Folic acid

b)

Cyanocobalamin

c)

Vitamin M

d)

Folacin

21.

All of the following alkaloids are anticholinergic agents, EXCEPT:

a)

Scopolwamine

b)

Atropine

c)

Pilocarpine

d)

Hyoscyamine

22.

When Socrates was sentenced to death, he chose to die by drinking a mixture containing arecoline and lobeline from poison hemlock.

a)

True

b)

False

23.

All are tropane alkaloids, EXCEPT:

a)

Quinidine

b)

Atropine

c)

Cocaine

d)

Hyoscyamine

24.

A hormone secreted from the thyroid gland which is one of the responsible for the regulation of Calcium:

a)

Calcitonin

b)

T3

c)

T4

d)

Thyroxine

25.

Composed of a benzene ring fused to a pyrrole ring:

a)

Imidazole

b)

Indole

c)

Purine

d)

Isoquinoline

26.

YOHIMBINE from the bark of Pausinystalia yohimbe is used for impotence.

a)

True

b)

False

27.

It is known as mandragora:

a)

European mandrake

b)

Areca catechu

c)

American mandrake

28.

Theophylline is 1, 3-dimethylxanthine while Theobromine is 3, 3- dimethylxanthine.

a)

True

b)

False

29.

Accepted use of ergotamine tartrate:

a)

Migraine

b)

Hallucinogenic

c)

Tocolytic agent

d)

Oxytocic agent

30.

Measle vaccine:

a)

Rubella vaccine

b)

Varicella vaccine

c)

Rubeola vaccine

d)

Variola vaccine

31.

STATEMENT 1: Cocaine is a tropane alkaloid.

STATEMENT 2: Cacaine is a miotic drug.

a)

Statement I only is true.

b)

Statement II only is true.

32.

↓ insulin

a)

Diabetes mellitus,

b)

Gigantism,

c)

Cretinism,

d)

Grave’s disease,

e)

Diabetes insipidus

33.

↑ growth hormone

a)

Diabetes mellitus,

b)

Gigantism,

c)

Cretinism,

d)

Grave’s disease,

e)

Diabetes insipidus

34.

↓ thyroid hormone

a)

Diabetes mellitus,

b)

Gigantism,

c)

Cretinism,

d)

Grave’s disease,

e)

Diabetes insipidus

35.

↑ thyroid hormone

a)

Diabetes mellitus,

b)

Gigantism,

c)

Cretinism,

d)

Grave’s disease,

e)

Diabetes insipidus

36.

↓ ADH

a)

Diabetes mellitus,

b)

Gigantism,

c)

Cretinism,

d)

Grave’s disease,

e)

Diabetes insipidus

37.

A hormone produced by alpha cells at the islet of Langerhans of pancreas:

a)

Insulin

b)

Glucagon

c)

Somatostatin

d)

Pancreatic polypeptide

38.

A combination of morphine /methadone + cocaine + alcohol:

a)

Brompton’s cocktail

b)

Dover’s powder

c)

Camphorated opium tincture

39.

Beta Pleated Sheet is a Secondary Protein Structure.

a)

True

b)

False

40.

The amino acid precursor of quinine in cinchona is:

a)

Tryptophan

b)

Valine

c)

Tyrosine

41.

The following hormones are secreted from adrenal medulla, EXCEPT:

a)

Glucocorticoids

b)

Dopamine

c)

NE

d)

Epinephrine

42.

A vitamin that is also used in the treatment of Alzeimer’s disease:

a)

Calciferol

b)

Tocopherol

c)

Phytonadione

43.

The poisonous Veratrum viride is an alkaloidal amine.

a)

True

b)

False

44.

Ergots are indole alkaloids from the fungus, Claviceps purpurea (Fam. Clavicipitaceae).

a)

True

b)

False

45.

Active component of Indian Tobacco:

a)

Lobeline

b)

Nicotine

c)

Atropine

46.

This is the new name of the family palmae.

a)

Arecaceae

b)

Fabaceae

c)

Apiaceae

47.

The following are examples of steroidal alkaloids, EXCEPT:

a)

Green hellebore

b)

Black hellebore

c)

White hellebore

d)

American hellebore

48.

The following are hallucinogens, EXCEPT:

a)

Morning glory

b)

Ryanodine

c)

Mescaline

d)

Psilocybine

49.

The "base" form of cocaine is neutralized by an acid to make the hydrochloride salt.

a)

True

b)

False

50.

IMIDAZOLE should not to be confused with pyrazole which has two adjacent nitrogen atoms.

a)

True

b)

False

51.

Pilocarpine is available in an ocular therapeutic system that provides continuous release over one week following placement in the conjunctival cul-de-sac.

a)

True

b)

False

52.

The four bisindole compounds present in nux vomica are vinblastine, vinleurosine, vinrosidine, and vincristine.

a)

False

b)

True

53.

Nicotinic acid contains a pyrimidine structure.

a)

True

b)

False

54.

Streptomyces griseus

a)

Streptomycin

b)

Oxytetracycline

c)

Penicillin,

d)

Bleomycin,

e)

Erythromycin

55.

Psilocybin is an alkaloidal amine.

a)

True

b)

False

56.

Hyoscine is the levo-isomer to atropine.

a)

True

b)

False

57.

Hygrine is hygroscopic.

a)

True

b)

False

58.

Chemically known as 3,4,5-trimethoxycinnamic acid:

a)

Theobromine

b)

Reserpine

c)

Rescinnamine

59.

TRUE about Mandragora, EXCEPT:

I. Also known as European mandrake

II. Also known as American mandrake

III. Botanical source: Mandragora officinarum (Solanaceae)

IV. Botanical source: Podophyllum peltatum (Berberidaceae)

a)

I and III only

b)

II and III only

c)

II and IV only

60.

The steroid nucleus is a fused ring system consisting of 4 cyclohexane rings and one cyclopentane ring.

a)

True

b)

False

61.

The anti-gout, Colchicine, is found in Colchicum autumnale and is a steroidal alkaloid.

a)

True

b)

False

62.

The following is/are true about alkaloids, EXCEPT:

a)

None of these

b)

They are heterocyclic nitrogenous compounds.

c)

They are Alkali-like.

d)

They are found in dicots and Monocots.

e)

They are basic in nature.

63.

PEYOTE is also called MESCAL BUTTONS.

a)

True

b)

False

64.

Which of the following hormone/s is/are stored in the posterior pituitary gland?

a)

Vasopressin

b)

ADH

c)

Oxytocin

d)

All of these

65.

KHAT OR ABYSSINIAN TEA is a purine alkaloid that contains (-)- cathinone.

a)

True

b)

False

66.

Cheilosis

a)

Vitamin C,

b)

Vitamin B9,

c)

Vitamin B2,

d)

Vitamin B1,

67.

Spina bifida

a)

Vitamin C,

b)

Vitamin B9,

c)

Vitamin B2,

d)

Vitamin B1,

68.

Carpal tunnel syndrome

a)

Vitamin C,

b)

Vitamin B9,

c)

Vitamin B2,

d)

Vitamin B1,

69.

Beriberi

a)

Vitamin C,

b)

Vitamin B9,

c)

Vitamin B2,

d)

Vitamin B1,

70.

Scurvy

a)

Vitamin C,

b)

Vitamin B9,

c)

Vitamin B2,

d)

Vitamin B1,

71.

Hemorrhagic diseases

a)

Vitamin K,

b)

Vitamin B2,

c)

Vitamin B5,

d)

Vitamin A,

72.

Glossitis

a)

Vitamin K,

b)

Vitamin B2,

c)

Vitamin B5,

d)

Vitamin A,

73.

Burning foot syndrome

a)

Vitamin K,

b)

Vitamin B2,

c)

Vitamin B5,

d)

Vitamin A,

74.

Xeropthalmia

a)

Vitamin K,

b)

Vitamin B2,

c)

Vitamin B5,

d)

Vitamin A,

75.

Achlorhydria

a)

Vitamin B12,

b)

Vitamin D,

c)

Vitamin E,

d)

Vitamin A,

76.

Rickets

a)

Vitamin B12,

b)

Vitamin D,

c)

Vitamin E,

d)

Vitamin A,

77.

Blood cells lysis and nerve damage

a)

Vitamin B12,

b)

Vitamin D,

c)

Vitamin E,

d)

Vitamin A,

78.

Bitot’s spot

a)

Vitamin B12,

b)

Vitamin D,

c)

Vitamin E,

d)

Vitamin A,

79.

Tetany

a)

Vitamin D,

b)

Vitamin B1,

c)

Vitamin B12,

d)

Vitamin B6,

80.

Wernicke-Korsakoff Syndrome

a)

Vitamin D,

b)

Vitamin B1,

c)

Vitamin B12,

d)

Vitamin B6,

81.

Pernicious anemia

a)

Vitamin D,

b)

Vitamin B1,

c)

Vitamin B12,

d)

Vitamin B6,

82.

Supplementation during isoniazid therapy to prevent peripheral neuropathy

a)

Vitamin D,

b)

Vitamin B1,

c)

Vitamin B12,

d)

Vitamin B6,

83.

Pellagra

a)

Vitamin B3,

b)

Vitamin A,

c)

Vitamin D

84.

Keratomalacia

a)

Vitamin B3,

b)

Vitamin A,

c)

Vitamin D

85.

Osteomalacia

a)

Vitamin B3,

b)

Vitamin A,

c)

Vitamin D

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