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IMHM WEEK 2

Total questions: 97

Worksheet time: 1hrs 11mins

Name
Class
Date
1.

Immunohematology is also known as?

(a)  

2.

may cause death to a patient when incompatible blood.

(a)  

3.

Refers to the process of collecting, storing, and processing blood and the distribution of RBCs and blood components

(a)  

4.

Branch of medicine that is concerned with transfusion of blood and blood components.

(a)  

5.

It is the first time a blood transfusion was recorded in history

a)

1492

b)

1867

c)

1869

d)

1873

6.

An english surgeon who uses antiseptics to control infection during transfusions

a)

Joseph Lister

b)

Braxton hicks

c)

Von Decastello

d)

Sturli

7.

What was the most used antiseptic in 1867?

(a)  

8.

What did Braxton Hicks recommends for a non toxic anticoagulant in 1869?

(a)  

9.

Who discovered of the ABO blood group system

(a)  

10.

If an agglutinogen is present on red blood cell membrane, the corresponding agglutinin must be ___ in the plasma

a)

absent

b)

present

11.

If an agglutinogen is absent on the red blood cell membrane, then corresponding agglutinin must be ___in the plasma

a)

absent

b)

present

12.

Agglutinin

a)

plasma

b)

heparin

13.

agglutinogen

a)

plasma

b)

heparin

14.

In what year did Landsteiner won a nobel price?

(a)  

15.

Who discovered the 4th blood type?

a)

Von Decastello and Sturli

b)

Alexis carrel

c)

Moreschi

d)

Braxton hicks

16.

suggests that the safety of transfusion might be improved by crossmatching

a)

Ludvig Hektoen

b)

Von Decastello and Sturli

c)

Alexis carrel

d)

Moreschi

17.

A french surgeon that devises a way to prevent clotting by sewing the vein of the recipient directly to the artery of the donor. The vein to artery or direct method, known as anastomosis, is practiced by a number of physicians

a)

Alexis carrel

b)

Ludvig Hektoen

c)

Moreschi

d)

Von Decastello and Sturli

18.

The vein to artery method is known as?

(a)  

19.

When did Alexis Carrel won a nobel prize?

(a)  

20.

He describes the anti human globulin AHG reaction

a)

Moreschi

b)

Ludvig Hektoen

c)

Alexis carrel

d)

Von Decastello and Sturli

21.

What is the meaning of AHG

(a)  

22.

A direct way of visualizing Ag-Ab reaction that has taken place but is not directly visible

(a)  

23.

in vivo sensitization of red blood cell

a)

direct AHG

b)

indirect AHG

c)

Coomb's test

24.

in vitro sensitization of red blood cell

a)

direct AHG

b)

indirect AHG

c)

coomb's test

25.

Other term possible used if we are referring to blood banking procedures

(a)  

26.

a visiting physician at the Massachusetts General hospital, along with Paul Dudley White, develops the Lee-White clotting time. Lee’s studies lead to the terms “universal donor” and “universal recipient”

a)

roger lee

b)

Edward E. Lindemann

c)

Albert Hustin

d)

Francis Rous and turner

27.

A procedure done to determine the clotting time of a certain patient. Clotting time is valuable for clotting disorder and preoperative condition

(a)  

28.

intended for packed RBC

a)

Universal donor / recipient

b)

Universal donor

c)

Universal recipient

29.

blood type O Rh negative (-) packed RBC

a)

Universal donor / recipient

b)

Universal donor

c)

Universal recipient

30.

blood type AB Rh positive (+) packed RBC

a)

Universal donor / recipient

b)

Universal recipient

c)

Universal donor

31.

He was the first to succeed to perform blood transfusion

a)

Edward E. Lindemann

b)

Lewisohn

c)

Francis Rous

d)

turner

32.

He reported the use of sodium citrate as an anticoagulant solution for trasnfusion

a)

Albert Hustin

b)

Lewisohn

c)

Francis Rous

d)

Turner

33.

determines the minimum amount of citrate needed for anticoagulation and demonstrated its nontoxicity in small amount

a)

Lewisohn

b)

Edward E. Lindemann

c)

Francis Rous

d)

Turner

34.

It binds to calcium and it will cause the patient to lead to hypocalcemia (low calcium).

(a)  

35.

They introduced citrate-dextrose solution for the preservation of blood

a)

Francis Rous and turner

b)

Lewisohn

c)

Edward E. Lindemann

d)

Albert Hustin

36.

Who originated the word "blood bank"

(a)  

37.

Director of therapeutics at the Cook County Hospital in Chicago, established the first hospital blood bank in the US. In creating a hospital laboratory that can preserve and store donor blood

a)

Bernard fantus

b)

Dr. Drew

c)

Edwin Cohn

d)

Loutit and Mollison

38.

Who was appointed director of the first American red Cross Blood Bank at Presbyterian Hospital

(a)  

39.

Introductory year of Rh blood group

(a)  

40.

a professor at biological chemistry at Harvard medical School, develops old ethanol fractionation

a)

Edwin Cohn

b)

Dr. Drew

c)

Loutit and Mollison

41.

It is the process of breaking down plasma into components and products

(a)  

42.

A protein with powerful osmotic properties, plus gamma globulin and fibrinogen are isolated and become availabel for clinical use

(a)  

43.

They introduced the formula for the preservation of Acid citrate dextrose (ACD)

(a)  

44.

describe the use of antihuman globulin AHG (later known as the “coombs test”) to identify “incomplete” antibodies

(a)  

45.

Its principle is to identify the unkown or unidentified antibody or incomplete antibody thru sensitization of RBC

(a)  

46.

What year did the AABB was formed to promot common goals among blood banking practioners and the blood donating public

(a)  

47.

She reports th euse of glyverol cryoprotectant for freezing RBCs

(a)  

48.

it is a method for freezing RBC

(a)  

49.

They introduced the plastic bag for blood collection

a)

Carl Walter and W.P. Murphy, Jr

b)

AABB clearinghouse

c)

Audrey Smith

d)

Coombs, Mourant, and race

50.

This was established, providing a centralized system for exhancging blood among blood banks

(a)  

51.

Designed for colleciton, storage, and transfusion of whole blood

a)

single bag

b)

double bag

c)

triple bag

d)

quadruple bag

52.

Separation of whole blood into red cell and plasma

a)

single bag

b)

double bag

c)

triple bag

d)

quadruple bag

53.

Separation of red cells, platelet concentrate and plasma

a)

single bag

b)

Double bag

c)

triple bag

d)

quadruple bag

54.

Separation into red cells, platelets concentrate, plsma and cryoprecipitate

a)

single bag

b)

double bag

c)

triple bag

d)

quadruple bag

55.

introduced an improved preservative solution, citrate-phosphate-dextrose (CPD), which was less acidic and eventually replaced ACD as the standard preservative used for blood storage

a)

Gibson

b)

Max Perutz

c)

A. Solomon

d)

J.L. Fahey

56.

the molecular structure of hemoglobin, the molecule that transport oxygen and gives red blood cells their color

a)

Max Perutz

b)

Gibson

c)

A. Solomon

d)

J.L. Fahey

57.

What replaced the ACD as the standard preservative used for blood storage?

(a)  

58.

Report the first therapeutic plasmapheresis procedure

a)

A. Solomon and J.L. Fahey

b)

Gibson

c)

Max Perutz

59.

The first antihemophilic factor (AHF) concentrate to treat coagulation disorders in hemophilia patients is developed through fractionation

a)

1962

b)

1961

c)

1963

d)

1964

60.

report a method for producing cryoprecipitate AHF for treatment of hemophilia

a)

Judith G. pool and Angela E. Shannon

b)

A. Solomon and J.L. Fahey

61.

It is commercially introduced to prevent Rh disease in the newborns of Rh negative women

(a)  

62.

demonstrated the feasibility of storing platelets at room temperature, revolutionizing platelet transfusion therapy

a)

S. Murphy and F. Gardner

b)

Judith G. pool and Angela E. Shannon

c)

Max Perutz

63.

Hepatitis B surface antigen (HBsAg) testing of donated blood begins

a)

1968

b)

1971

c)

1969

d)

1970

64.

It was a new anticoagulant preservative that extends the shelf life of whole blood ans RBC to 35 days

(a)  

65.

What were the 2 tests that screen for indirect evidence of hepatitis that was developed and implemented?

(a)  

66.

Introduction of first specific test for hepatitis c, the major cause of non A, non B” hepatitis

a)

1990

b)

1991

c)

1992

d)

1993

67.

They are units of inheritance that encode for certain traits or visible characteristics

(a)  

68.

linear arrangement of genes

a)

genes

b)

chromsomes

c)

phenotype

d)

genotype

69.

How many are chromosome pairs?

(a)  

70.

How many are chromsomes?

(a)  

71.

it is the physical expression of inherited genes

a)

alleles

b)

genotype

c)

phenotype

d)

chromosomes

72.

the set of alleles for given trait carried by an organism

a)

genotype

b)

alleles

c)

locus

d)

autosomal

73.

They are defined as alternative forms of a gene. A portion within the chromosome that codes for the traits/ genes

a)

Genotype

b)

Alleles

c)

Autosomal

d)

Sex linked

74.

specific location of genes within the chromosome

(a)  

75.

inherited on one of the 22 pairs of autosomal chromosomes

a)

Alleles

b)

Locus

c)

Autosomal

d)

Sex linked

76.

genes inherited on the sex chromosomes (X chromosomes)

a)

Locus

b)

Autosomal

c)

Sex linked

d)

Alleles

77.

a gene that is when expressed whenever the allele is present

(a)  

78.

A gene that is not expressed even the allele is present. Silent gene / amorph gene can only be expressed if two identical genes are present. They are heterozygous

(a)  

79.

A pair of genes in which neither is dominant over the other. Two different genes that are inherited at the same loci on a pair of chromosomes

(a)  

80.

having two identical genes for a given trait

a)

heterozygous

b)

homozygous

81.

Having two unidentical genes for a given trait

a)

homozygous

b)

heterozygous

82.

Who is the father of genetics?

(a)  

83.

An Australian monk and mathematician who used sweet pea plants growing in a monastery garden to study physical traits in organisms and how they are inherited

(a)  

84.

What are the 2 laws that gregor mendel has studied

(a)  

85.

Crossbreed of homozygous red and homozygous white flower (Rr)

a)

First filial generation

b)

Second filial generation

c)

1st generation – “Parental”

86.

Crossbreed of first filial generation

a)

·       1st generation – “Parental”

b)

First filial generation

c)

Second filial generation

87.

States that “genes for different traits are inherited separately from each other”

a)

LAW OF INDEPENDENT ASSORTMENT

b)

LAW OF INDEPENDENT SEGREGATION

88.

In inheritance pattern the MALES are represented by?

a)

circle

b)

square

c)

vertical line

d)

small black circle

89.

In inheritance pattern the FEMALES are represented by?

a)

squares

b)

circles

c)

double line

d)

triangle

90.

In inheritance pattern the OFFSPRING is represented by?

(a)  

91.

in inheritance patterns: Between a male and female indicates a consanguineous mating

a)

vertical line

b)

double line

c)

Small black circle

d)

line crossed through them

92.

In inheritance pattern A stillbirth of abortion is indicated by a

a)

vertical line

b)

double line

c)

Small black circle

d)

circle

93.

in inheritance pattern the Deceased family members have

a)

circle

b)

square

c)

double line

d)

line acrossed through them

94.

it indicates the most interesting or important member of the pedigree

a)

circle

b)

line crossed through them

c)

arrow pointing to it

95.

It refers to traits that are not carried on the sex chromosome

(a)  

96.

It is carried by either parent or both parents but is not generally seen at the phenotypic level unless both parents carry the trait

(a)  

97.

It illustrates the probabilities of phenotypes from known or inferred genotypes

(a)