Active Artificial Immunity is induced by vaccine that contains which of the ff?

1-Toxoid, 2-dead typhoid bacteria, 3-IgG, 4-Live small pox virus

A newborn infant gets immune antibodies from his mother through the colostrum during breast feeding. What adaptive immunity is involved?

A thermolabile protein present in normal serum is known as:

Chemical reagent(s) that distinguishes IgG from IgM antibodies. This substance denatures IgM by breaking its disulfide bonds.

Kupffer cell is the macrophage that is found in the ______ tissue.

Natural Immunity is represented by which of the ff. defense systems? 1-Acidity of Gatro intestinal tract, 2- Interferons, 3-IgG, 4-Lymphokines

The first leukocyte to migrate to the area of damaged/infected tissues during inflammatory response.

The most potent phagocytic cell and most effective APC is

This interleukin inhibits cytokine synthesis.

Transfer of antibodies through the injection is classified as:

What cytokine stimulate trans-endothelial leukocyte movement from the blood to the tissue site of infection and regulate the migration of PMNs and mononuclear leukocytes within tissues?

What is the leukocyte that mediates cellular immunity of an individual?

What is the name of the process by which phagocytic cells are attracted to a substance such as a bacterial peptide?

Which of the ff interleukins will act as a growth factors to B- cells?

1-IL-1

2-IL-4

3-IL-5

4-IL-6

Which of the ff is routinely included in compatibility testing?

1-ABO/Rh testing of donor and recipient

2-antibody screening of donor

3-Minor crossmatch

4-Major crossmatch

Which of the ff. are true for ADAPTIVE IMMUNITY?

1-Specific in nature

2-Secondary response has the same magnitude as that of the primary response

3-It produces memory cells

4-It is the first line of defense.

Which of the following cytokines stimulates hematopoeitic cells and supports the growth of bone marrow stem cells?

where is histamine synthesized?

largest white blood cell found in the blood

potent enzyme that kills bacteria through respiratory burst

arginine rich protein that has anti-parasitic activity

located on the skin and the mucous membranes

what is the speed of response for neutrophils

what is the speed of response for macrophage

what type of phagocytosis is it if opsonins are not involved?

it is sensitive to acute stage inflammation but it is non-specific

can be found in tears, saliva, and other secretions

type of cytokines which transmits between similar type of cells

type of cytokines which transmits between different types of cells

produced by immunologically stimulated, primarily T lymphocytes

means of communication between leukocytes

produced mainly by macrophages or monocytes

lymphocyte activating factor

key cell involved in immune response

lymphoid organ where differentiation, development, and maturation occurs

Which among the CD markers are used to identify B-cells?

1 - CD 19

2 - CD 20

3 - CD 22

4 - CD 21

5 - CD 17

B-cell responsible for antibody production

exhibit identifying marker CD25

recognize antigen upon reexposure

first antibody to have a complete set of structure?

Which CD markers are specific for T-cells

1 - CD1

2- CD2

3- CD3

4- CD4

5- CD8

6-CD21

7-CD16

8-CD56

Which CD markers are specific for NK CELLS

1 - CD1

2- CD2

3- CD3

4- CD4

5- CD8

6-CD21

7-CD16

8-CD56

thymocytes that lacks both CD4 and CD8

thymocytes that has both CD4 and CD8

thymocytes that has either CD4 or CD8

most immunocompetent, is CD4 positive, collaborates with B-cells

CD8 positive and controls and inhibits antibody production

- has the ability to destroy virally infected cells or tumor cells

- not MHC class restricted

- aka "kiss of death"

stimulated by IL-2 to help lyse tumor cells

lyse target cells by using antibody-dependent cell mediated cytolysis (ADCC)

Statement 1: Nonspecific function of monocytes and macrophage is phagocytosis

Statement 2: Specific function of monocytes and macrophage is antigen presenting cell (APC)

what CD is the marker receptor on the surface of different cytotoxic cells?

It is the most common technique separating lymphocytes from the peripheral blood sample

this test is specific for b-cells and its method is immunoenzymatic method

an old method for the presumptive identification of T-cells and is specific for t-cells only

responsible for the molecular weight of the antigen

determines the specificity of the antigen

antigens that belong to the host

heteroantigens that exist in unrelated plants or animals but are identical or closely related in structure

antigens derived from other species that are introduced to human

antigens from other members of the same host's species

transplant derived from identical member of host's species

it is the best and strongest antigen

least immunogenic

chemical agents that when added to antigen can induce or enhance immune response

special class of immunogen that induces hypersensitivity reactions

strength of attraction between an epitope and an antigen combining site of an antibody

strength of attraction between complex antigens and antibodies

treatment with papain will produce which fragments

treatment with pepsin will produce which fragments

what chromosome does heavy chain synthesis occur?

which chromosome does light chain kappa synthesis occur?

which chromosome does light chain lambda synthesis occur?

What test is used to identify S. pneumoniae infection?

What test is used to identify Diphtheria

What test is used to identify Hydatid

gene tumor marker for CML

best tumor marker for prostate cancer

tumor marker for ovarian cancer

tumor marker for gastric cancer

tumor marker for hepatocellular cancer

Identify which type of hypersensitivity:

- 5 to 8 hours

- Ab directed against cell-surface antigens

Identify which type of hypersensitivity:

- 2 to 8 hours

- Ag-Ab complexes deposit at various sites

- soluble antigens involved

Identify which type of hypersensitivity:

- 2 to 30 mins

- IgE antibody is involved

most severe type of hypersensitivity

which among the IgG can cross the placenta?

Arrange from most to least potent

Identify which antibody is being described:

- cold antibody

- biggest antibody

- primary response antibody

Identify which antibody is being described:

- mucosal immunity

- seen in breastmilk

- monomer and dimer

Identify which antibody is being described:

- warm antibody

-predominant in humans

- best precipitating antibody

- smallest antibody

Identify which antibody is being described:

- least abundant

- heat labile

- binds strongly to mast cell and basophil

C3 convertase of classical pathway

C3 convertase of alternative pathway

C5 convertase of alternative pathway

activating substance is Mannose

phase where antibody is not yet detectable

antibody titer increases exponentially

anamestic or memory response

Statement 1: Primary response has a longer plateau phase

Statement 2: Secondary response has a shorter lag phase

which class of MHC is being described?

- present in all nucleated cells

- presented to CD8 positive cells or T suppressor type of cells

- includes HLA-A, HLA-B, HLA-C, B2-microglobulin, HLA-E

Statement 1: If lymphocytes stain blue or pink, it has HLA MHC I antigens

Statement 2: If lymphocytes don't stain blue or punk, it does not have HLA MHC I antigens

which class of MHC is being described?

- restricted to immunocompetent cells

- present in macrophages, b-cells, and dendritic cells

- includes HLA-DP, HLA-DQ, HLA-DR

HLA that causes ankylosing spondylitis

HLA that causes Rheumatoid Arthritis

HLA that causes SLE

HLA that causes Goodpasture's syndrome

which class of MHC is being described?

- minor MHC antigens

- involves complement components such as C2, C4, and Factor B/C3 proactivate