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ib biology 7.2 + 7.3

Total questions: 60

Worksheet time: 36mins

Name
Class
Date
1.

How can environmental factors affect the expression of genes?

a)

By promoting the replication of nucleosomes

b)

By inactivating epinephrine

c)

By making specific changes to the base sequence of genes

d)

By causing the pattern of DNA methylation to be changed

e)

By changing the patterns of methylation and acetylation on the histone proteins

2.

State a chemical modification of a nucleosome that could impact gene expression.

(a)  

3.

Some regions of DNA do not code for the production of proteins. What are these regions of DNA used as?

a)

They have no known function and are recycled to provide nucleotides

b)

Gene regulation and coding for production of enzymes used in translation

c)

Telomeres and coding for production of tRNA

d)

Introns and coding for production of structural proteins

4.

In which process(es) do nucleosomes play a role in eukaryotes?

I. tRNA activation

II. Transcription regulation

III. DNA supercoiling

a)

I only

b)

II only

c)

II and III only

d)

I, II and III only

5.

How many different forms of RNA are involved with protein synthesis in cells?

(a)  

6.

Which of these modifications is likely to result in euchromatin, DNA that is loosely bound to the nucleosome?

a)

Methylation

b)

Acetylation

c)

Denaturation

d)

Phosphorylation

7.

What word describes the study of changes in phenotype as a result of variations in gene expression levels

(a)  

8.

A gene has highly methylated DNA. How is this likely to affect gene expression?

a)

Prevents transcription factors from binding so increases gene expression

b)

Prevents transcription factors from binding so decreases gene expression

c)

Facilitates binding of transcription factors so increases gene expression

d)

Facilitates binding of transcription factors so decreases gene expression

9.

What is the 'Central Dogma' of biology?

a)

DNA ---> RNA ---> Protein

b)

RNA ---> DNA ---> Protein

c)

Protein ---> RNA ---> DNA

d)

DNA ---> Protein ---> RNA

10.

What are the two overarching processes within the 'Central Dogma'

a)

Replication and translation

b)

Transcription and replication

c)

Transcription and translation

d)

Protein synthesis and DNA replication

11.

What is the function of RNA polymerase?

a)

Adds DNA nucleotides to the 3' end of a growing strand

b)

Adds RNA nucleotides to the 3' end of a growing strand

c)

Adds DNA nucleotides to the 5' end of a growing strand

d)

Adds RNA nucleotides to the 5' end of a growing strand

12.

Which answer shows the sections of a gene in the correct order?

a)

Promoter, coding sequence, terminator

b)

Coding sequence, promoter, terminator

c)

Terminator, coding sequence, promoter

d)

Promoter, terminator, coding sequence

13.

When does transcription stop?

a)

When RNA polymerase detaches from the DNA

b)

When the terminator sequence is reached

c)

When the end of the coding sequence is reached

d)

When there are no more nucleotides left

14.

What binds to the promoter to initiate transcription?

a)

Transcription factor protein

b)

RNA polymerase enzyme

c)

Complementary RNA nucleotides

d)

DNA helicase

15.

Which of the following is not a feature of post-transcription?

a)

Removal of exons by splicing

b)

Addition of a 5' methyl cap

c)

Addition of a 3' poly-A tail

16.

Which of the following statements is incorrect?

a)

The mRNA strand is complementary to the antisense DNA strand

b)

The mRNA strand is identical to the antisense DNA strand, except for uracil

c)

The mRNA strand is identical to the sense DNA strand, except for uracil

17.

Which of the following is not a possible result of alternative splicing for a gene consisting of 4 exons?

a)

2-3-4

b)

1-2-4

c)

1-3

d)

1-3-2

18.

If the antisense strand of a gene has the sequence AAT-GCC, what will be the transcribed mRNA sequence?

a)

AAU-GCC

b)

TTA-GCC

c)

AAT-GCC

d)

UUA-GCC

19.

What is a promoter region?

a)

A non-coding section of a gene that immediately precedes the coding sequence

b)

A non-coding section of a gene that immediately follows the coding sequence

c)

A coding section of a gene that immediately precedes the terminator

d)

A coding section of a gene that immediately follows the terminator

20.

The sense and antisense strands of DNA are the same for every gene on a chromosome.

a)

True

b)

False

21.

Which type of RNA is a copy of a gene used to encode a polypeptide?

a)

mRNA

b)

tRNA

c)

rRNA

22.

The synthesis of mRNA copied from the DNA base sequence is known as

a)

transcription

b)

translation

c)

replication

23.

The enzyme that binds to a site on the DNA, separates the strands, and covalently bonds ribonucleside triphosphates opposite their complementary partner is

a)

RNA Polymerase

b)

DNA Polymerase

c)

DNA Helicase

d)

RNA Primase

24.

The nucleotides are aligned with their complementary partners on which strand of DNA?

a)

DNA antisense strand

b)

DNA sense strand

25.

Which region of DNA is edited out of mRNA and recycled into nucleotides?

a)

introns

b)

exons

26.

The sequence of DNA that serves as the attachment point for RNA polymerase is called what?

a)

promoter

b)

enhancer

c)

silencer

27.

What is the name of the key chemical group that can be added to DNA to inhibit transcription?

a)

methyl group

b)

acetyl group

c)

study group

d)

phosphate group

28.

State the direction of transcription

a)

5' --> 3'

b)

3' --> 5'

29.
Which of the following would be a nucleotide found in DNA
a)
Ribose + phosphate + uracil
b)
Deoxyribose + phosphate + uracil  
c)
Deoxyribose + phosphate + adenine
d)
Ribose + phosphate + adenine
30.
An RNA molecule is
a)
double helix
b)
always double stranded
c)
usually double stranded
d)
single stranded
31.
What is the correct sequence?
a)
RNA --> DNA --> Protein
b)
Protein --> RNA --> DNA
c)
DNA --> RNA --> Protein
d)
DNA --> Protein --> RNA
32.
Where does transcription take place?
a)
nucleus
b)
cytoplasm
c)
ribosome
33.
Which RNA bases would pair with TACGAA in transcription? 
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
34.
What is the difference between DNA and RNA in terms of bases?
a)
RNA contains uracil in place of thymine
b)
RNA contains uracil in place of adenine
c)
RNA contains uracil in place of guanine
d)
RNA contains uracil in place of  cytosine
35.
What are the three components of a nucleotide?
a)
sugar, hydrogen, nitrogen base
b)
sugar, oxygen, nitrogen base
c)
sugar, phosphate, nitrogen base
d)
sugar, phosphate, protein
36.

Which type of RNA is a copy of a gene used to encode a polypeptide?

a)

mRNA

b)

tRNA

c)

rRNA

37.

The synthesis of mRNA copied from the DNA base sequence is known as

a)

transcription

b)

translation

c)

replication

38.

The enzyme that binds to a site on the DNA, separates the strands, and covalently bonds ribonucleside triphosphates opposite their complementary partner is

a)

RNA Polymerase

b)

DNA Polymerase

c)

DNA Helicase

d)

RNA Primase

39.

The nucleotides are aligned with their complementary partners on which strand of DNA?

a)

DNA antisense strand

b)

DNA sense strand

40.

Which region of DNA is edited out of mRNA and recycled into nucleotides?

a)

introns

b)

exons

41.

The sequence of DNA that serves as the attachment point for RNA polymerase is called what?

a)

promoter

b)

enhancer

c)

silencer

42.

What is the name of the key chemical group that can be added to DNA to inhibit transcription?

a)

methyl group

b)

acetyl group

c)

study group

d)

phosphate group

43.

State the direction of transcription

a)

5' --> 3'

b)

3' --> 5'

44.
Which of the following would be a nucleotide found in DNA
a)
Ribose + phosphate + uracil
b)
Deoxyribose + phosphate + uracil  
c)
Deoxyribose + phosphate + adenine
d)
Ribose + phosphate + adenine
45.
An RNA molecule is
a)
double helix
b)
always double stranded
c)
usually double stranded
d)
single stranded
46.
What is the correct sequence?
a)
RNA --> DNA --> Protein
b)
Protein --> RNA --> DNA
c)
DNA --> RNA --> Protein
d)
DNA --> Protein --> RNA
47.
Where does transcription take place?
a)
nucleus
b)
cytoplasm
c)
ribosome
48.
Which RNA bases would pair with TACGAA in transcription? 
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
49.
What is the difference between DNA and RNA in terms of bases?
a)
RNA contains uracil in place of thymine
b)
RNA contains uracil in place of adenine
c)
RNA contains uracil in place of guanine
d)
RNA contains uracil in place of  cytosine
50.
What are the three components of a nucleotide?
a)
sugar, hydrogen, nitrogen base
b)
sugar, oxygen, nitrogen base
c)
sugar, phosphate, nitrogen base
d)
sugar, phosphate, protein
51.

What is the following molecule?

a)

triglyceride

b)

phospholipid

c)

steroid

d)

protein

52.

What is the following molecule?

a)

protein

b)

triglyceride

c)

lipid

d)

steroid

53.

What is the following molecule?

a)

triglyceride

b)

steroid

c)

phospholipid

d)

nucleic acid

54.

What is the following molecule?

a)

alpha glcuose

b)

beta glucose

c)

nucleic acid

d)

disaccharide

55.

What is the following molecule?

a)

alpha glcuose

b)

beta glucose

c)

amino acid

d)

disaccharide

56.

What is the following molecule?

a)

alpha glcuose

b)

beta glucose

c)

amino acid

d)

disaccharide

57.

What is the following molecule?

a)

alpha glcuose

b)

beta glucose

c)

amino acid

d)

disaccharide

58.

What is the following molecule?

a)

alpha glcuose

b)

saturated fat

c)

unsaturated fat

d)

protein

59.

What is the following molecule?

a)

alpha glcuose

b)

saturated fat

c)

unsaturated fat

d)

protein

60.

What kind of bond is shown in the following diagram?

a)

glycosidic bond

b)

peptide bond

c)

covalent bond

d)

ionic bond

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