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AP bio DNA structure and Replication

Total questions: 38

Worksheet time: 57mins

Name
Class
Date
1.
What are the 4 nitrogen bases?
a)
adenine, thymine, cytoplasm, and guanine
b)
adenine, thymine cytosine, and guanine
c)
adenine, thymine, cytosine, and gylcerol
d)
adenine, thymine, cytosine, and glucose
2.
Which 2 molecules forms the sides (backbone) of the DNA ladder?
a)
deoxyribose and adenine
b)
deoxyribose and a hydrogen bond
c)
sugar and the nucleus
d)
deoxyribose (sugar) and phosphate
3.
Which of the following best describes a DNA molecule?
a)
double helix
b)
contains ribose
c)
made of amino acids
d)
contains Uracil
4.
Which of the following units are repeatedly joined together to form a strand of DNA? (This is the MONOMER of DNA.) 
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides
5.

Adenine base pairs with ______________ on the opposite DNA strand

a)

Guanine

b)

Thymine

c)

Cytosine

d)

Adenine

6.
Guanine bonds with ______________.
a)
Adenine
b)
Guanine
c)
Cytosine
d)
Thymine
7.
When DNA has finished Replication, which of the following has been created?
a)
Four new double stranded DNA molecules.
b)
Two old Stranded DNA Molecules
c)
Two Double Stranded DNA Molecules, each with one old strand and one new strand.
d)
No new DNA is generated.
8.
In a molecule of double-stranded DNA, the amount of Adenine present is always equal to the amount of
a)
cytosine
b)
guanine
c)
thymine
d)
uracil
9.
The term used to describe DNA Replication is:
a)
Semi-Conservative
b)
Conservative
c)
AntiParallel
d)
Dispersive
10.

Who determined DNA to be a transforming agent that caused bacteria to “transform” from one type to another?

a)

Crick

b)

Sanger

c)

Fred Griffith

d)

Mullins

11.
If Chargaff found that a sample of DNA has 20% ADENINE, how much GUANINE would he have determined to be there?
a)
30%
b)
20%
c)
80%
d)
60%
12.
The result of Hershey and Chase's T2 experiments showed that the _____ of the virus enters the host where viral replication takes place.
a)
DNA
b)
Protein
c)
Both DNA & Protein
13.
How did Rosalind Franklin's photo 51 affect the work of Watson and Crick?
a)
It was used to determine the physical structure of DNA
b)
It was used to identify the four bases that make up DNA
c)
It was used to determine the theory of independent assortment
d)
It was used to show DNA was the molecule of inheritance
14.

Which strain of bacteria was harmless in Griffith's experiments?

a)

S-strain

b)

R-strain

c)

T-strain

d)

B-strain

15.

When the mixture of heat-killed S-strain and R-strain bacteria was injected into the mice, what happened?

a)

The mice died

b)

The mice remained healthy

c)

The mice changed colors

d)

The mice got mean

16.
Identify the correct Purine nitrogen bases.
a)
Thymine and Cytosine
b)
Adenine and Guanine
c)
Adenine and Thymine
d)
Guanine and Cytosine 
17.
Identify the correct Pyrimidine nitrogen bases.
a)
Adenine and Guanine
b)
Thymine and Guanine
c)
Thymine and Cytosine
d)
Adenine and Cytosine 
18.
The bond that holds the nitrogenous bases together are WEAK bonds called:
a)
Hydrogen Bonds
b)
Nitrogen Bonds
c)
Carbon Bonds
d)
Phosphodiester Bonds
19.
Which statement about DNA structure is correct?
a)
The two strands are identical and run in the same direction. 
b)
The two sides are identical and run in opposite direction. 
c)
The two sides are complementary and run in the same direction.
d)
The two sides are complementary and run in opposite direction.  
20.
A nucleotide is made of 
a)
A nitrogen,a ribose sugar, and protein. 
b)
A phosphate, a deoxyribose sugar, and a carbon base.
c)
Adenine, guanine, cytosine, and  thymine.
d)
A phosphate, deoxyribose sugar, and a nitrogen base.
21.
There are _________ bonds between Adenine and Thymine and ________ bonds between Guanine and Cytosine . 
a)
Two;Three
b)
Two;Four
c)
Three;Two
d)
Four;Two 
22.

This is what part of the nucleotide?

a)

phosphate group

b)

nitrogen base

c)

sugar

d)

fatty acid

23.

This is what part of the nucleotide?

a)

phosphate group

b)

nitrogen base

c)

sugar

d)

fatty acid

24.

This is what part of the nucleotide?

a)

phosphate group

b)

nitrogen base

c)

sugar

d)

fatty acid

25.

The picture below shows an enzyme unwinding and unzipping DNA.

​

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

26.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

27.

Where does the DNA molecule unzip at during DNA replication?

a)

Between the sugar and phosphate

b)

Between the sugar and nitrogen bases

c)

Between the nitrogen bases

28.
Which enzyme is responsible for adding nucleotides?
a)
Topoisomerase
b)
DNA Polymerase
c)
Ligase
d)
Primase
29.

Which enzyme is responsible for adding the free nucleotides to the replicating DNA? ​

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

30.

Which is the second step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

31.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

32.

You are given the DNA strand 5'ATGCTCAGCTGA3'. What is the corresponding DNA strand?

a)

5'UACGAGUCGACU3'

b)

5'TACGAGTCGACT3'

c)

3'UACGAGUCGACU5'

d)

3'TACGAGTCGACT5'

33.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

34.

Which letter in the picture below depicts the lagging strand in DNA replication?

a)

Letter A since it is copied from 5' to 3'

b)

Letter A since it is copied from 3' to 5'

c)

Letter B since it is copied from 3' to 5

d)

Letter B since it is copied from 5' to 3'

35.

DNA replication puts down nucleotides ______' to _____' and is said to be ______________________

a)

5, 3, antiparallel

b)

3, 5, antiparallel

c)

5, 3, parallel

d)

3, 5, parallel

36.

DNA replication takes place in eukaryotic cells during which phase?

a)

G1

b)

S

c)

M

d)

G0

37.

Which enzyme joins the Okazaki fragments in the lagging strand?

a)

Helicase

b)

DNA Polymerase

c)

Ligase

d)

Primase

38.

In the Meselson-Stahl experiment, E.coli was transfered from 15N medium to 14N medium. Centrifugation of DNA after 20 minutes in 14N produced ____ and disproved the ____ model.

a)

1 intermediate band, conservative

b)

1 intermediate band, dispersive

c)

1 heavy band and 1 light band, semi-conservative

d)

1 light and 1 intermediate band, dispersive

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