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Adaptive Immunity

Total questions: 54

Worksheet time: 1hrs 21mins

Name
Class
Date
1.

An immunity that is the type of host defense that is always present in healthy individuals. It is always ready and prepared to prevent infection

a)

Innate immunity

b)

Adaptive immunity

c)

Humoral Immunity

d)

Cell-mediated immunity

2.

An immunity that is a type of host defense that always requires activation and stimulation in order to respond most effectively

a)

Innate immunity

b)

Adaptive immunity

c)

Native immunity

d)

Humoral Immunity

3.

Which of the following is NOT part of innate immunity?

a)

Inflammation

b)

Complement proteins

c)

Phagocytosis

d)

Antibodies

4.

Which of the following are appropriate descriptions of the adaptive immune system?

a)

Nonspecific

b)

Fastest type of immune responses

c)

Long term memory

d)

Specific

e)

No memory

5.

Which is true regarding the lymphatic system? (select all that apply)

a)

T cells are only located in the thymus

b)

there are lymph nodes located throughout the body

c)

B cells are only located in the bone marrow

d)

there are lymphoid tissues in our gut and mucosal areas

6.

Which organ is where lymphocytes mature into T cells?

a)

Bone marrow

b)

Thymus

c)

Spleen

d)

Lymph nodes

7.

The site where all immune cells originate from is

a)

Bone Borrow

b)

Thymus

c)

Spleen

d)

Liver

8.

The site(s) where B cells and T cells encounter many microbes and immune responses may take place

a)

thymus

b)

blood

c)

secondary lymphoid organs

d)

bone marrow

9.

The location in the body where lymphocytes mature into B cells is the

a)

thymus

b)

blood

c)

lymph nodes

d)

bone marrow

10.

The site in the body where B cells and T cells are activated is the

a)

bone marrow

b)

thymus

c)

lymph nodes

d)

tissues

11.

Any substance that causes your immune system to produce antibodies is a(n)

a)

interferon

b)

Toxin

c)

immunoglobulin

d)

Antigen

12.

Which of the following are true regarding antigens?

a)

they are often parts of microbes

b)

they can be proteins

c)

they can be found in the environment (like pollen)

d)

they are found on our human cells

13.

Antibodies are also called

a)

antigens

b)

immunoglobulins

c)

serum

d)

complement

14.

What is the primary responsibility of B cells?

a)

Produce immunoglobulin

b)

Lysis of virus infected cells

c)

Phagocytosis of pathogens

d)

Differentiate into different types of immune cells

15.

Which antibody is primarily involved in allergic reactions?

a)

IgA

b)

IgD

c)

IgE

d)

IgM

16.

The first class of antibody that is produced the first time the body encounters a pathogen (primary immune response) is

a)

IgG

b)

IgM

c)

IgA

d)

IgE

17.

The class of antibody that is most important for the memory immune response (secondary immune response) is

a)

IgM

b)

IgA

c)

IgE

d)

IgG

18.

The class of antibody that is most prevalent in the mucous membranes is

a)

IgA

b)

IgG

c)

IgM

d)

IgE

19.

The most prevelant class of antibody found in our serum is

a)

IgA

b)

IgM

c)

IgE

d)

IgG

20.

The class of antibody that is passed from a pregnant mom to the fetus is

a)

IgG

b)

IgM

c)

IgE

d)

IgA

21.

Each antibody recognizes and binds

a)

a specific B cell

b)

a specific T cell

c)

a specific antigen

d)

a specific lymph node

22.

The region of an antibody molecule that is specific for binding to an antigen is the

a)

Fab region

b)

Fc region

c)

spike

d)

complement

23.

Which of the following statement is TRUE?

a)

Acquired immunity is not specific

b)

Innate immune response is enhanced after repeated exposure

c)

Adaptive immunity response is immediate

d)

Adaptive immunity produces memory cells

24.

B cells make and secrete antibodies

a)

as soon as the B cell matures in the bone marrow

b)

only when a person becomes an adult

c)

after the B cell has become activated

d)

directly after it is made in the bone marrow

25.

In order for a B cell to become activated it has to (select all that apply)

a)

release IgM

b)

bind to it's specific antigen

c)

receive help (cytokines) from a T cell

d)

bind to a CD4+ T cell via an MHC-antigen complex

e)

bind to an antigen presenting cell

26.

Vaccination is an example of

a)

Naturally acquired active immunity

b)

Artificially acquired active immunity

c)

Naturally acquired passive immunity

d)

Artificially acquired passive immunity

27.

Newborns get some antibodies from mothers breastmilk. This is an example of

a)

Naturally acquired active immunity

b)

Artificially acquired active immunity

c)

Naturally acquired passive immunity

d)

Artificially acquired passive immunity

28.

This refers to the type of immunity developed when a person is exposed to a pathogen:

a)

naturally acquired active immunity

b)

naturally acquired passive immunity

c)

artificially acquired active immunity

d)

artificially acquired passive immunity

29.

What is herd immunity?

a)

The number of disease-fighting white blood cells in a person

b)

Large number of individuals in a community becomes immune to a disease

c)

Immunity in a herd of cows

d)

The number of people that opt out of getting vaccinations

30.

The cells which provide signals to B cells for complete activation

a)

macrophages

b)

CD8+ T cells

c)

CD4+ T cells

d)

stem cells

31.

Also known as an immunoglobulin (Ig), this is a large, Y-shaped protein produced by plasma cells that are used by the immune system to identify and neutralize pathogens such as bacteria and viruses.

a)

B cells

b)

T cells

c)

Antibody

d)

Antigen

32.

An example of Innate Immunity:

a)

Skin

b)

B cells

c)

T cells

d)

Lymphocytes

33.

Which part of our immune system are we not born with?

a)

innate

b)

adaptive

c)

barrier

34.
A type of T cell that destroys infected cells is a:
a)

cytotoxic T cell

b)

helper T cell

c)

memory T cell

d)

suppressor T cell

35.

Identify the given structure

a)

antigen

b)

antibody

c)

hormone

d)

MHC

36.

What do memory B cells do?

a)

Kills the virus

b)

Eats the virus

c)

Patrol the area and make the immune system work faster next time.

d)

Makes antibodies

37.

Plasma cells

a)

enhance the secondary immune response

b)

produce CD4+ T cells

c)

produce antibodies

d)

activate B cells

38.

Neutralization is when

a)

antibodies bind to an antigen and activate complement

b)

antibodies bind to an antigen and enhance phagocytosis

c)

antibodies bind to an antigen and stop the antigen from binding to host cells

d)

antibodies bind to antigens and cause them to clump together

39.

Opsonization is when

a)

antibodies bind to an antigen and activate complement

b)

antibodies bind to an antigen and enhance phagocytosis

c)

antibodies bind to an antigen and stop the antigen from binding to host cells

d)

antibodies bind to antigens and cause them to clump together

40.

Agglutination is when

a)

antibodies bind to an antigen and activate complement

b)

antibodies bind to an antigen and enhance phagocytosis

c)

antibodies bind to an antigen and stop the antigen from binding to host cells

d)

antibodies bind to antigens and cause them to clump together

41.

This refers to the type of immunity developed when a person was exposed to a disease and is immediately given preformed antibodies in a clinical setting

a)

naturally acquired active immunity

b)

naturally acquired passive immunity

c)

artificially acquired active immunity

d)

artificially acquired passive immunity

42.

The secondary immune response refers to

a)

the immunity from the adaptive immune system

b)

the second time the immune system encounters an antigen

c)

the second line of immune defense- the innate immune system

d)

the second time a person gets sick from a disease

43.

In the secondary immune response (select all that apply)

a)

antibodies are produced more quickly after exposure than they were produced during initial exposure

b)

the innate immune system is not important

c)

the amount of antibodies produced is greater than the initial exposure

d)

T cells are not needed

44.

What must happen to activate a T cell?

a)

The T cell receptor binds to it's antigen bound to an MHC molecule

b)

An antigen presenting cell releases cytokines

c)

The T cell binds to a CD4+ T cell

d)

The T cell immunoglobulin binds to it's specific antigen

45.

Activated CD 8+ T cells function to

a)

release antibodies

b)

activate B cells and other immune cells

c)

act as antigen presenting cells

d)

recognize and kill target cells

46.

Activated CD 4+ T cells function to

a)

release antibodies

b)

activate B cells and other immune cells

c)

act as antigen presenting cells

d)

recognize and kill target cells

47.

Cytokines are important in immune responses because they (select all that apply)

a)

bind to antigens

b)

activate immune cells

c)

recruit immune cells to the area

d)

enhance the overall immune resposne

e)

cause antibodies to divide

48.

With which type of vaccines is there NO risk of becoming infected or ill with the disease? (select all that apply)

a)

attenuated vaccine

b)

killed/inactivated vaccine

c)

Nucleic acid vaccine

d)

Subunit vaccine

49.

Which type of immune hypersensitivity reaction is mediated by T cells?

a)

Type l (immediate hypersensitivity)

b)

Type ll (Cytotoxic)

c)

Type lll (Immune complex)

d)

Type lV (Cell Mediated)

50.

Which type of immune hypersensitivity reactions are mediated by antibodies (select all that apply)?

a)

Type l (immediate hypersensitivity)

b)

Type ll (Cytotoxic)

c)

Type lll (Immune complex)

d)

Type lV (Cell Mediated)

51.

A person with Type A blood (select all that apply)

a)

has A antigens on their red blood cells

b)

has B antigens on their red blood cells

c)

produces antibodies to B antigens

d)

cannot receive Type B blood

52.

A person with Type O blood (select all that apply)

a)

has A antigens on their red blood cells

b)

has B antigens on their red blood cells

c)

produces antibodies to B antigens

d)

produces antibodies to A antigens

e)

has neither A antigens or B antigens on their red blood cells

53.

A person who is Rh+ (select all that apply)

a)

expresses the Rh antigen on their cells

b)

makes antibodies to Rh factor

c)

has type O blood

d)

could have an Rh+ child

54.

Hemolytic disease of the newborn can occur when

a)

An Rh+ mom is pregnant with an Rh- fetus

b)

An Rh- mom is pregnant with an Rh+ fetus

c)

An Rh- mom is pregnant with an Rh- fetus

d)

An Rh+ mom is pregnant with an Rh+ fetus