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DNA, RNA, Mutations, Transcription, Translation, Lac Operon

Total questions: 71

Worksheet time: 42mins

Name
Class
Date
1.

All cells carry the entire genome of an organism apart from:

a)

hair follicles and gametes.

b)

skin cells and gametes.

c)

gametes and red blood cells.

d)

gametes.

2.

Gene expression is the ability for a gene to be:

a)

in the genome.

b)

transcribed.

c)

non-coding.

d)

a dominant allele.

3.

Which RNA type is the result of transcription?

a)

tRNA

b)

Non-coding RNA

c)

rRNA

d)

mRNA

4.

Which of the following is correct?

a)

Nucleotide triplets code a single amino acid.

b)

Each amino acid codes a nucleotide.

c)

Each nucleotide codes an amino acid.

d)

Amino acid triplets code a single nucleotide.

5.

RNA substitutes uracil for which nucleotide?

a)

Adenine

b)

Cytosine

c)

Guanine

d)

Thymine

6.

Translation is a process where:

a)

a polypeptide sequence is produced from a sequence of rRNA codons.

b)

a polypeptide sequence is produced from a sequence of tRNA codons.

c)

a polypeptide sequence is produced from a sequence of mRNA codons.

d)

a DNA nucleotide sequence is used to produce mRNA codon sequence.

7.

Gene regulation occurs:

a)

only in some cells.

b)

when the variability within the genetic code is insufficiently adaptive for the individual to survive in its environment.

c)

constantly, in all known life forms.

d)

during embryonic development.

8.
_______ is to transcription as ________ is to translation.
a)
mRNA / Amino Acid Chain
b)
Amino Acid Chain / mRNA
c)
Ribosome / Nucleus
d)
mRNA / tRNA
9.
Which of these processes begin with an mRNA molecule?
a)
DNA Replication
b)
Transcription
c)
Translation
d)
None of them
10.

Translation in eukaryotes occurs:

a)

outside of the nucleus.

b)

inside of the nucleus.

11.
What structure of this molecule binds with the mRNA molecule?
a)
Amino Acid
b)
tRNA
c)
Anticodon
d)
Codon
12.

True or False: All of your body cells contain the same genes.

a)

True

b)

False

13.

What is an operon?

a)

a part of a ribsome

b)

a part of a Rna

c)

a unit made up of linked genes that code for proteins needed to do a specific task

d)

needed for dna replication

14.
An operon consists of all the the following EXCEPT
a)
operator
b)
promoter
c)
regulatory gene
d)
genes of the operon
15.

Operons are found in which of the following organisms?

a)

Bacteria(prokaryotes)

b)

plants and animals(eukaryotes)

c)

only animals

d)

virsuses

16.
The "on/off" switch for an operon is called the
a)
promoter
b)
repressor
c)
operator
d)
gene
17.

What does a promoter do?

a)

binds RNA polymerase for transcription

b)

binds DNA polymerase for replication

c)

binds the operator

d)

binds the repressor

18.
A protein that binds to the operator and blocks the RNA polymerase
a)
regulator
b)
repressor
c)
activator
d)
corepressor
19.

The lac operon genes only become expressed if:

a)

lactose binds to repressor

b)

glucose binds to repressor

c)

repressor binds to operator

d)

lactose binds to operator

20.
What is the role of operons in prokaryote gene expression?
a)
It makes the genes prokaryotes be turned on
b)
It accounts for the regulation of gene activity in response to the needs of the cells
c)
To make DNA for the gene
d)
To make the gene turn of and off
21.
Most gene regulation happens at which step along the way?
a)
translation
b)
transcription
c)
signal transduction
d)
DNA replication
22.

What is the name of the stretch of DNA where RNA polymerase binds?

a)

operator

b)

promoter

c)

enhancer

d)

regulatory gene

23.

What does the lactose do to the Operon?

a)

Blocks transcription of the lactase gene by cutting up the DNA

b)

Binds to the repressor preventing it from attaching to the operator

c)

The lactose binds promoter to prevent transcription

d)

Allows for the transcription rate of lactase to slow down

24.

In the lac operon the inducer is

a)

lactose

b)

glucose

c)

galactose

d)

all of the above

25.

What is 1 in the diagram?

a)

RNA polymerase

b)

Inducer

c)

Repressor

d)

Operator

26.

What is 2 in the diagram?

a)

RNA polymerase

b)

Inducer

c)

Repressor

d)

Operator

27.

What type of operon is the trp (tryptophan) operon?

a)

inducible

b)

repressible

c)

positive control

d)

promotor

28.

Which of the following are part of a bacterial lac operon? (Select all that apply)

a)

Promotor

b)

Genes for lac enzymes

c)

Regulatory genes

d)

Enhancers

29.

Match the following genetic regions to their roles:

a)

Makes a repressor protein

1.

Regulatory gene

b)

Place where transcription begins

2.

Promotor

c)

The on/off switch where the repressor protein binds

3.

Operator

d)

Codes for the main protein / enzymes

4.

Genes of Operon

30.

The operon model was discovered in E. Coli and is almost exclusively found in ​ (a)   .

Choose from the below words
prokaryotes
eukaryotes
31.

What type of molecule helps turn on specific genes?

a)

Inducers

b)

Repressors

c)

Methalation

d)

Morphogenesis

32.
Chunks of three bases on the mRNA that code for a specific amino acids are called...
a)
Codons
b)
Snodocs
c)
Docons
d)
Nocods
33.
In eukaryotes, where does transcription occur?
a)
Nucleus
b)
Cytoplasm
c)
Outside of the cell
d)
Eukaryotes don't do transcription
34.
Other than mRNA, what is this image showing?
a)
tRNA
b)
rRNA
c)
DNA
d)
RNA polymerase
35.
What is one easy way to tell RNA from DNA?
a)
RNA has uracil, DNA doesn't
b)
DNA doesn't have thymine, RNA does
c)
RNA is double stranded, DNA isn't
d)
RNA is made of up amino acids, DNA isn't
36.
In translation..
a)
A polypeptide is created
b)
mRNA is created
c)
The nucleus implodes
d)
RNA polymerase does all the work
37.
What is the anticodon if the codon is "AAA"?
a)
UUU
b)
TTT
c)
AAA
d)
GGG
38.
When a mutation only changes one base (adding, deleting, or substracting), we call that a...
a)
point mutation
b)
delta mutation
c)
transcription
d)
translation
39.
What is the name for those letters in DNA and RNA (A, T, C, and G)?
a)
Amino acids
b)
Monosaccharides
c)
Nitrogenous bases 
d)
Phosphate groups
40.
How many bases are in two codons?
a)
6
b)
12
c)
3
d)
1
41.
True/False: Bacteria do not use DNA to store their genetic information.
a)
True
b)
False
42.
What is the term for making an RNA copy of DNA?
a)
Transcription
b)
Translation
c)
Folding
d)
Coding
43.
Translation happens at the - 
a)
Nucleus
b)
Ribosome
c)
Chloroplast
d)
Mitochondria
44.
Does the order of amino acids in a protein matter?
a)
YES!
b)
NO!
45.
Which enzyme is responsible for making RNA?
a)
RNA makemorease
b)
RNA enzymase
c)
RNA polymerase
d)
RNA proliferase
46.
If the percentage of DNA is made of 30% Thymine, what is the correct percentage of Guanine?
a)
30
b)
15
c)
20
d)
60
47.
True or false:  RNA is double-stranded.
a)
True
b)
False
c)
It depends on the type
48.
Where does the RNA polymerase bind to and start on the DNA?
a)
Promoter
b)
Operator
c)
Lactose
d)
At the tripe uracil anticodon
49.

In each of your human body cells, there are ​ (a)   chromosomes, existing in ​ (b)   pairs.

Choose from the below words
46
23
64
32
50.

Each gene along a strand of DNA has the information to tell the cell to produce a specific ​ (a)   . A gene is made up of a particular ​ (b)   of DNA bases. This sequence acts as a ​ (c)   for a protein.

Choose from the below words
protein
sequence
code
51.

​ (a)   is a specific combination of alleles for a given gene. ​ (b)   is the physical manifestation of the organism's genotype.

Choose from the below words
Genotype
Phenotype
52.

​ (a)   is the type of RNA that is a newly formed strand of complementary bases with the completion of transcription and exits the nucleus.

Choose from the below words
mRNA
tRNA
rRNA
53.

Which enzyme is responsible for bonding new nucleotides together in a chain to make a new RNA molecule?


(a)  
Choose from the below words
RNA polymerase
DNA polymerase
54.

What is the basic shape of DNA?

a)

Single stranded

b)

Double helix

c)

triple stranded

55.

_____________: A change in the DNA sequence of a chromosome

a)

Translation

b)

Replication

c)

Transcription

d)

Mutation

56.

_____________: A single stranded nucleic acid that can be used to make proteins; composed of the nucleotides adenine, guanine, cytosine, and uracil

a)

RNA

b)

Chromosome

c)

DNA

d)

Chromatin

57.

_____________: Relaxed form of DNA that is present in the nucleus during interphase of eukaryotic cells

a)

RNA

b)

Chromosome

c)

DNA

d)

Chromatin

58.

_____________: A segment of DNA that encodes a protein or functional RNA

a)

DNA

b)

RNA

c)

Gene

d)

Chromosome

59.

What type of mutation involves adding or deleting bases from the DNA, which results in new codons (a shift in the reading of the codons)?

a)

point mutation

b)

frameshift mutation

c)

silent mutation

d)

chromosomal mutation

60.

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC GTA CTT GAA T

What type of mutation has occurred?

a)

Chromosomal mutation

b)

Point mutation

c)

Frameshift mutation due to adding extra base

d)

Frameshift mutation due to deletion of base

61.

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC GAC TTG AAT

What type of mutation has occurred?

a)

Chromosomal mutation

b)

Point mutation

c)

Frameshift mutation

d)

No mutation occurred

62.

What type of chromosomal mutation occurred?

a)

chromosomal insertion/duplication

b)

chromosomal deletion

c)

chromosomal inversion

d)

chromosomal translocation

63.

What type of chromosomal mutation occurred?

a)

chromosomal insertion/duplication

b)

chromosomal deletion

c)

chromosomal inversion

d)

chromosomal translocation

64.

What type of chromosomal mutation occurred?

a)

chromosomal insertion/duplication

b)

chromosomal deletion

c)

chromosomal inversion

d)

chromosomal translocation

65.

What type of chromosomal mutation occurred?

a)

chromosomal insertion/duplication

b)

chromosomal deletion

c)

chromosomal inversion

d)

chromosomal translocation

66.

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC ACT TGA AT

What type of mutation has occurred?

a)

Chromosomal mutation

b)

Point mutation

c)

Frameshift mutation due to addition of base

d)

Frameshift mutation due to deletion of base

67.

What are considered "negative" mutations?

a)

mutations in the DNA sequence that changes the resulting protein and harms the organism

b)

mutations in the DNA sequence that changes the resulting protein and benefits the organism

c)

mutations in the DNA sequence that produces the same protein

d)

all mutations are considered bad and harm the organisms

68.
The study of the genome is known as
a)
Biology
b)
Genomics
c)
Genes
d)
Heredity
69.
What is DNA sequencing?
a)
The total of genes carried by an individual or cell
b)
Coding genes in order to identify single nucleotide polymorphisms
c)
Deciphering the functions of various parts of the human genome
d)
The process of identifying the order of the bases in DNA
70.
The genomes of two unrelated humans are ___% the same.
a)
90.0
b)
0.1%
c)
78%
d)
99.9%
71.
How many base pairs (bp) are in the human genome?
a)
1 billion bp
b)
4 billion bp
c)
3 billion bp
d)
3.5 billion bp