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WorksheetsAntibiotics/Antimicrobials
Total questions: 22
Worksheet time: 33mins
Which type of antibiotics are most likely to cause side-effects?
Narrow spectrum antibiotics
Broad spectrum antibiotics
Antibiotics made from plants
Antibiotics made from animals
What is antibiotic resistance?
The ability of antibiotics to fight viral infections
The ability of bacteria to multiply rapidly
The ability of previously sensitive species of bacteria to resist the effects of antibiotics
The ability of antibiotics to cure all types of infections
In general, what is the common mechanism of action of antifungals?
stop cell wall synthesis
stop protein synthesis
stop nucleic acid synthesis
they target sterols in the plasma membrane
What drug is the most versatile and effective antifungal and is often used to treat systemic fungal infections?
Amphotericin B
Vancomycin
miconazole
tetracycline
Why is it necessary to practice HAART when treating HIV?
the antiviral drugs are broad spectrum
there are few points in the replication cycle where we can target HIV
HIV replicates very rapidly
to decrease the development of drug resistant virus
Selective toxicity means that
the drug kills only a small subset of microbes
the drug kills bacteria but not helminths
the drug kills microbes but is not harmful to the host
the drug can be used at a wide range of concentrations
It is most difficult to find a drug with selective toxicity when
the microbe is prokaryotic
the microbe is a bacteria
the microbe has been newly discovered
the microbe has many cellular similarities to human cells
The first discovered antibiotic was
tetracycline
novobiocin
penicillin
azithromycin
Over half of the antibiotics are made by
bacteria
fungi
helminths
protozoa
Which of the following are mechanisms of action of antimicrobial drugs (choose all that apply)
damaging the plasma membrane
inhibit nucleic acid synthesis
altering cell surface receptors on the bacteria
inhibit metabolic pathways
Beta-lactamases are enzymes that (choose all that apply)
make penicillin
cleave the ring structure of penicillins
are made by humans
are made by some bacteria
Ampicillin and amoxicillin
are used to treat fungal infections
are effective only against Gram positive bacteria
are effective against Gram positive and Gram negative bacteria
target nucleic acid synthesis of bacteria
Carbapenems
are used to treat fungal infections
are effective against most organisms isolated from hospital patients
are effective antivirals
are used to treat ear infections
This term describes when the effect of two drugs together is greater than the effect of either alone
synergism
selective toxicity
broad spectrum
commensalism
Which is NOT one of the antibiotics typically contained in over the counter antibiotic cream?
bacitracin
erythromycin
neomycin
polymyxin B
Which of the following are mechanisms that bacteria use for antibiotic resistance? (select all that apply)
pump the drug out of the cell
destroy/cleave the drug
block/decrease entry of the drug into the cell
use an alternative metabolic/enzymatic pathway than is targeted by the drug
trap the drug in vescicles within the bacterial cell
Which of the following are true of vancomycin? (choose all that apply)
it is used to treat MRSA
use is often restricted to most life-threatening conditions
used to treat ear and upper respiratory infections
used to treat yeast infections
The original drug that was used to treat malaria is
miconazole
amphotericin B
quinine
rimantadine
Erythromycin and Azithromycin are used to treat
fungal infections
influenza
ear and respiratory infections and others commonly caused by Staph and Strep
malaria
Tetracycline (choose all that apply)
is a broad spectrum antibiotic
is useful for intracellular infections such as Rocky Mt. Spotted Fever
can be used to treat Lyme disease
is commonly added to animal feed
Interferons are used as treatment for what types of infections?
viral
fungal
bacterial
protozoal
Which of the following might be used to treat fungal infections? (choose all that apply)
miconazole
fluconazole
ketoconazole
primaquine
amphotericin B
