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Protein Synthesis and Mutations

Total questions: 42

Worksheet time: 4hrs 30mins

Name
Class
Date
1.

Which of the following are differences in the structure between RNA and DNA

a)

DNA uses deoxyribose sugar, RNA uses sugar ribose

b)

DNA pairs Adenine with Uracil, RNA pairs Adenine with Thymine

c)

DNA is a double helix, RNA is a single helix

d)

DNA pairs Adenine with Thymine, RNA pairs Adenine with Uracil

2.

These building blocks consist of a sugar, phosphate, and nitrogen base.

a)

Ribose

b)

Nucleotide

c)

Gene

d)

Protein

3.

Which of the following is the complementary mRNA sequence to this DNA strand: AACTGAA

a)

UUGACUU

b)

TTGACTT

c)

AACTGAA

d)

AACUGAA

4.
In RNA, Uracil pairs with ______. 
a)
cytosine
b)
adenine
c)
guanine
d)
thymine
5.
Does the order of amino acids in a protein matter?
a)
YES!
b)
NO!
6.
How many amino acids are coded for by this sequence of nucleotides:
ATG GGA ACT CCA
a)
4
b)
2
c)
6
d)
12
7.
Which is the mRNA molecule that would be transcribed from this DNA template:
TGGCAAGTACGT
a)
ACCGTTCATGCA
b)
UGGCAAGUACGU
c)
UCCGUUCUUGCU
d)
ACCGUUCAUGCA
8.

What is the result of translation?

a)

The synthesis of RNA from protein

b)

The synthesis of protein from RNA

c)

The synthesis of protein from DNA

d)

The synthesis of RNA from DNA

9.

What is the result of transcription?

a)

The synthesis of RNA from protein

b)

The synthesis of protein from RNA

c)

The synthesis of protein from DNA

d)

The synthesis of RNA from DNA

10.

Can more than one codon code for the same type of amino acid?

a)

yes

b)

no

11.

When reading the codon chart, which molecule do you reference?

a)

DNA

b)

mRNA

c)

tRNA

d)

rRNA

12.

All of the following are TRUE about ribonucleic acid EXCEPT

a)

It contains the sugar deoxyribose

b)

It contains the bases adenine, uracil. guanine and cytosine.

c)

It is typically single stranded.

d)

It has three main distinct types.

13.

Location for the process of transcription.

a)

nucleus

b)

nucleolus

c)

ribosome

d)

mitochondria

14.

The process of transcription starts at

a)

AUG, the start codon.

b)

UAA, the start codon.

c)

GUA, the start codon.

d)

TAG, the start codon.

15.

UAA, UAG, and UGA are all

a)

stop codons.

b)

start codons.

c)

intron sequences.

d)

exon sequences.

16.

Based on this diagram, what kind of mutation is the sickle cell mutation?

a)

Point, missense

b)

Point, nonsense

c)

Point, silent

d)

Frameshift

17.

What kind of mutation is shown in this diagram?

a)

Point, missense

b)

Point, nonsense

c)

Point, silent

d)

Frameshift

18.

What kind of mutation is shown in this diagram?

a)

Point, missense

b)

Point, nonsense

c)

Point, silent

d)

Frameshift

19.

What kind of mutation is shown in this diagram?

a)

Point, missense

b)

Point, nonsense

c)

Point, silent

d)

Frameshift

20.

What kind of mutation is shown in this diagram?

a)

Point, missense

b)

Point, nonsense

c)

Point, silent

d)

Frameshift

21.

Mutations in which there is a deletion or insertion of one or more bases in the DNA are

a)

chromosomal mutation.

b)

point mutation.

c)

spontaneous mutation.

d)

frameshift mutations.

22.

Monosomies and trisomies are examples of

a)

chromosomal mutations.

b)

point mutation.

c)

spontaneous mutations.

d)

frameshift mutation.

23.

Non-disjuction events are one cause of

a)

chromosomal mutations.

b)

point mutation.

c)

spontaneous mutations.

d)

frameshift mutation.

24.

A frameshift mutation where a nucleotide base

is removed from the DNA sequence.

a)

Deletion Mutation

b)

Substitution Mutation

c)

Translocation

d)

Silent Mutation

25.

A frameshift mutation where a nucleotide base is added

to the DNA sequence

a)

Insertion Mutation

b)

Deletion Mutation

c)

Substitution Mutation

d)

Chromosomal Mutation

26.

A point mutation where one nucleotide base replaces an original nucleotide base

a)

Inversion Mutation

b)

Chromosomal Mutation

c)

Translocation

d)

Substitution Mutation

27.

One nucleotide base is changed so only one amino acid

is affected

a)

Substitution Mutation

b)

Point Mutation

c)

Translocation

d)

Inverse Mutation

28.

A change in a gene, group of genes or chromosome that results in a change in the proteins

a)

Replication

b)

Mutations

c)

Translation

d)

Transcription

29.

Genetic mutations can be...

a)

beneficial, harmful, or neutral

b)

beneficial only

c)

harmful only

d)

neutral only

30.
Identify the DELETION mutation form the following: 
ATG CCA AAT
a)
ATG TCA AAT
b)
ATG CCT AAA T
c)
ATC CA  AT
d)
ATG CCA AAT
31.
ATTTGAGCC- Original
ATTGAGCC - Mutated
The example above is an example of a 
a)
Insertion- Frameshift
b)
Deletion- Substitution
c)
Deletion -Frameshift
d)
All of the above
32.
original chromosome
ABC-DEF
mutated chromosome
AC-DEF
This is a _____________ mutation.
a)
frameshift
b)
point
c)
deletion
33.
What amino acid is represented by the codon CAG?
a)
Aspartic Acid
b)
Histidine
c)
Glutamine
d)
Methionine
34.

What is the amino acid for the mRNA codon UUC?

a)

Phe

b)

Met

c)

Gly

d)

Stop

35.

What is the amino acid for the mRNA codon AUG?

(a)  

36.

What is the amino acid for the mRNA codon UAC?

a)

Tyrosine

b)

Histidine

c)

Serine

d)

Valine

37.

What is the amino acid for the mRNA codon UGA?

(a)  

38.

Codons consist of how many bases or "nucleotides"?  

a)

1

b)

2

c)

3

d)

4

39.

the repeating units that form a DNA and an RNA molecule are?

a)

fatty acids

b)

nucleotides

c)

amino acids

d)

chromosomes

40.

DNA replication results in two DNA molecules,

a)

each w/ 2 new strands

b)

`1 w/ two new strands and the other with 2 originial

c)

each with 1 new strand and one original

d)

each with two original strands

41.

DNA or RNA?

single stranded

a)

DNA

b)

RNA

42.

DNA or RNA?

stays in nucleus

a)

DNA

b)

RNA