Font size
WorksheetsRAD 231 - Week 3 Exam
Total questions: 73
Worksheet time: 37mins
A ____________ radiation response occurs within days after exposure.
stochastic
probabilistic
deterministic
nonthreshold
A _____________ response to radiation occurs months or years after radiation exposure.
deterministic
threshold
characteristic
stochastic
At the molecular level, the human body is made up of approximately 80% ___________.
protein
carbohydrates
DNA
water
About 15% of the human body at the molecular level is compose of ________________.
water
protein
carbohydrates
nucleic acids
True or false: When the LET is high, ionizations are high.
True
False
What is the RBE of diagnostic x-rays?
0.5
1
2
20
What is the effect on relative biologic effectiveness (RBE) as linear energy transfer (LET) increases?
As LET increases, RBE increases
As LET increases, RBE decreases
As LET increases, RBE stabilizes
LET has no effect on RBE
An x-ray interaction between cellular components is random. Consequently, when an interaction occurs with a target molecule it occurs ____________.
selectively
randomly
only with the cytoplasm
in vitro
How much time must elapse between radiation dosages to allow for the cell regeneration time?
8 hours
12 hours
24 hours
72 hours
What type of effect occurs when one section of a macromolecule attaches to a nearby macromolecule or another part of the same molecule?
point lesion
cross linking
main chain scission
main chain scission, only one side rail severed
Which of the following is not an effect of irradiation of DNA?
main chain scission, one side rail severed
main chain scission, both side rails severed
main chain scission with rails inversion
main chain scission, cross linking
Which of the following can result from irradiation of DNA? (Choose 3)
Cell death
skin reddening
malignant disease
genetic effects
If the initial ionizing even occurs on a distant, noncritical molecule which then transfers the energy of ionization to the target molecule, a(n) _____________ effect has occurred.
direct
indirect
obtuse
transfer
Review the Law of Bergonie and Tribondeau!!!!!!!!!!! Know the components!
Okay
I
Will
Brad
___________ forms a single helix, ___________ forms a double helix.
DNA; RNA
Protein; RNA
RNA; DNA
DNA; DNA
Two types of cells that are very sensitive to higher radiation doses are:
lymphocytes
neurons
muscle cells
spermatogonia
____________ effects of radiation on human beings include cancer, leukemia, genetic effects, and malignant diseases.
deterministic
stochastic
threshold
tissue effects
___________ effects on human beings include skin reddening, sterility, hair loss.
stochastic
probabilistic
deterministic
nonthreshold
At approximately 80% of the human body, this is the most abundant macromolecule in the human body.
hydrogen peroxide
water
DNA
Protein
_____________responses to radiation suggest that any dose can cause a response, regardless of the size.
Threshold
Nonthreshold
LET
OER
Nonlinear threshold dose responses describe stochastic effects.
True
False
When a radiation dose is delivered continuously at a lower dose rate, the dosage is said to be:
fractionated
protracted
regimented
equalized
When an atom loses an electron, potentially resulting in the breaking of a chemical bond, this constitutes ______________.
inactivation
ionization
direct effects
polymerization
LET is another method of expressing radiation:
quantity
quality
dose
response
Protein synthesis is an example of:
catabolism
metabolism
anabolism
cellular respiration
Dose modulation should be used frequently in CT imaging because:
it will increase patient dose
it will decrease patient dose
it will improve image quality
it will improve diagnosis
Dose responses without a threshold are called:
deterministic effects
stochastic effects
tissue effects
cause and effect responses
Macromolecules include which of the following?
lipid
amino acid
salt
free radical
Where is RNA principally located where in the cell?
mitochondria
nucleus
cytoplasm
lysosomes
DNA and RNA are classified as:
proteins
lipids
nucleic acids
amino acids
True or false: Bone marrow is radioresistant.
True
False
True or false: Bone marrow is more radiosensitive than thyroid tissue.
True
False
True or false: Brain tissue is more radioresistant than bone marrow.
True
False
Protraction is related predominantly to:
dose accumulation
dose rate
dose
dose response
When are humans most sensitive to radition?
humans are not sensitive to radiation
during older age
during adolescence
in vitro
If an irradiated cell dies before the next mitosis, this is called:
clonal death
interphase death
metaphase death
M death
After a low radiation dose, most cellular radiation damage that results in a late total-body effect occurs because of _______________.
cross linking
main chain scission
point lesions
in vitro effect
When a hit occurs through _______________, the size of the target appears considerably larger because of the mobility of free radicals.
direct effect
indirect effect
main chain scission
mean dose
Which of the following is true regarding the target theory?
hits can only occur by direct effect
radiation will always hit the target molecule
radiation interacts randomly
radiation and target molecules can be located at any time
True or false: The multitarget, single-hit model presumes a threshold.
True
False
True or false: The multitarget model of cell lethality states that cells have more than one critical target, each of which has to be inactivated for cell death.
True
False
A dose equal to D37, if randomly distributed, would cause what percentage of cells to die?
0%
37%
63%
100%
True or false: Diagnostic x-rays cause the production of free radical ions that are associated with biologic injury.
True
False
True or false: Undifferentiated cells in vivo are sensitive to radiation exposure.
True
False
True or false: Stem cells are radioresistant.
True
False
Radiation responses in the body begin with:
latent effects
point lesions
ionizations
cancer
The response of tissue to radiation exposure is primarily related to:
dose
LET
OER
RBE
A small D0 indicates:
radiation resistance
radiation sensitivity
no correlation to radiation dosage
the amount needed to produce any effect
Effects of radiation where the probability of occurrence, not severity of occurrence, is proportional to the dose are called:
stochastic effects
deterministic effects
genetic effects
somatic effects
Effects of radiation that become more severe as dose increases are called:
dose-response curves
deterministic effects
genetic effects
somatic effects
Which of the following means there is a safe level of radiation for certain effects and those effects are not directly proportional to the dose received when the safe level is exceeded?
nonlinear-nonthreshold effect
linear-nonthreshold effect
linear-threshold effect
nonlinear-threshold effect
Which of the following means there is a safe level of radiation for certain effects and those effects are directly proportional to the dose received when the safe level is exceeded?
Nonlinear-nonthreshold effect
Linear-nonthreshold effect
Linear-threshold effect
Nonlinear-threshold effect
Which of the following means there is no safe level of radiation and the response to the radiation is directly proportional to the dose received?
Nonlinear-nonthreshold effect
Linear-nonthreshold effect
Linear-threshold effect
Nonlinear-threshold effect
Which of the following means there is no safe level of radiation and the response to the radiation is not directly proportional to the dose received?
Nonlinear-nonthreshold effect
Linear-nonthreshold effect
Linear-threshold effect
Nonlinear-threshold effect
Which of the following is the basis for all radiation protection standards?
Nonlinear-nonthreshold effect
Linear-nonthreshold effect
Linear-threshold effect
Nonlinear-threshold effect
The phases of the cellular life cycle, in order, are:
Prophase, metaphase, anaphase, telophase
Interphase, prophase, metaphase, anaphase, telophase
G1, S, G2, telophase
Interphase (G1, S, G2), prophase, metaphase, anaphase, telophase
The process of cell division for germ cells is called:
mitosis
spermatogenesis
organogenesis
meiosis
Which of the following occurs when radiation transfers its energy to DNA?
indirect effect
target theory
direct effect
mutations
Which of the following states that each cell has a master molecule that directs all cellular activities and that, if inactivated, results in cellular death?
indirect effect
target theory
direct effect
mutations
What occurs when radiation transfers its energy to the cellular cytoplasm?
indirect effect
target theory
direct effect
doubling dose
Which of the following induces radiolysis?
indirect effect
target theory
direct effect
doubling dose
Cell radiosensitivity is described by the:
inverse square law
Law of Bergonie and Tribondeau
Reciprocity law
Ohm's law
Cells are more radiosensitive when:
fully oxygenated
deoxygenated
slowly dividing
near the skin
Which of the following poisons the cell with H2O2?
indirect effect
target theory
direct effect
doubling dose
Which of the following is responsible for producing free radicals?
indirect effect
target theory
direct effect
doubling dose
What is the name for changes in genetic code passed on to the next generation?
indirect effect
target theory
direct effect
mutations
Cells that are least sensitive to radiation exposure include:
ova and sperm
epithelial cells
nerve and muscle cells
blood cells
The most radiosensitive cells in the body are:
lymphocytes
epithelial cells
nerve cells
muscle cells
Which of the following ionizing radiations is described as having an RBE of 1.0?
10 MeV protons
5 MeV alpha particles
Diagnostic x-rays
Fast neutrons
How do fractionation and protraction affect radiation dose effects?
1. They reduce the effect of radiation exposure
2. They permit cellular repair
3. They allow tissue recovery
1 only
1 and 2 only
2 and 3 only
1, 2, and 3
All the following function to reduce patient dose except:
beam restriction
high kVp, low mAs factors
a high-speed grid
a high-speed imaging system
Which of the following radiation situations is potentially the most harmful?
A large dose to a specific area all at once.
A small dose to the whole body over a period of time.
A large dose to the whole body all at one time.
A small dose to a specific area over a period of time.
Which interaction between ionizing radiation and the target molecule involves formation of a free radical?
direct effect
indirect effect
target effect
random effect
