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Patho Exam 1 Quiz

Total questions: 78

Worksheet time: 40mins

Name
Class
Date
1.

When a patient asks the nurse what hypersensitivity is, how should the nurse respond? Hypersensitivity is best defined as:

a)

a. a reduced immune response found in most pathologic states.

b)

b. a normal immune response to an infectious agent.

c)

c. an excessive or inappropriate response of the immune system to a sensitizing antigen.

d)

d. antigenic desensitization

2.

A 75-year-old male presents with chest pain on exertion. The chest pain is most likely due to hypoxic injury caused (secondary to) by:

a)

a. Ischemia

b)

b. Chemical injury

c)

c. Diabetes

d)

d. Alcohol toxicity

3.

Sodium and water accumulation in an injured cell are a direct result of: (select all that apply)

a)

a. Failure of Na/K active transport pump

b)

b. Inflammatory response

c)

c. Insufficient nutrients

d)

d. Hypoxic injury

4.

A syndrome refers to signs and symptoms that emerge from a diseased state (T or F)

a)

True

b)

False

5.

The brain is the most common site for what type of necrosis?

a)

1. Caseous

b)

2. Liquefactive

c)

3. Fat

d)

4. Coagulative

6.

When a patient presents at the emergency department for an allergic reaction, the nurse recognizes the most severe consequence of a type I hypersensitivity reaction is:

a)

a. urticaria.

b)

b. hives.

c)

Anaphylaxis

d)

antibody-dependent cell-mediated cytotoxicity

7.

A 30-year-old female complains of fatigue, arthritis, rash, and changes in urine color. Laboratory testing reveals anemia, lymphopenia, and kidney inflammation. Assuming a diagnosis of SLE, which of the following is also likely to be present?

a)

Anti-LE antibodies

b)

Autoantibodies

c)

Anti Herpes antibodies

d)

Anti-CMV antibodies

8.

A 22-year-old was recently diagnosed with acquired immunodeficiency syndrome (AIDS). Which decreased lab findings would be expected to accompany this virus?

a)

CD4+ T-helper

b)

CD8 T-helper

c)

CDC cells

d)

CDC10 cells

9.

Which statement describes an individual who is sensitized and is predisposed to a type I hypersensitivity reaction?

a)

mast cells are degranulated

b)

urticaria has developed on the skin

c)

antigens have bound to IgE receptors on mast cells

d)

Attachment of large amounts of IgE to mast cell membranes has occurred

10.

True or false: Serotonin is the major vasoactive amine released by mast cells. It causes dilation of the capillaries which increases vascular permeability.

a)

True

b)

False

11.

What does healing by secondary intention mean? Select all that apply (SATA).

a)

Requires more time to treat

b)

Healing occurs from the bottom up

c)

Dermal edges are close together

d)

Results in a complete return to function

12.

What causes the redness, heat, swelling, and pain in inflammation? Select all that apply (SATA).

a)

Increased blood flow allows more immune cells to be carried to the injured tissue

b)

Increased Capillary permeability

c)

Bacteria is bursting in the blood causing macrophages to eat the cell

d)

Plasma proteins are not being synthesized in the kidneys

e)

Bradykinins

13.

Asthma is considered an acute airway inflammatory disease resulting in dysfunction of the airways and tissue remodeling. True or False?

a)

True

b)

False

14.

A disease has spread across the United States border. This is considered a...

a)

Epidemic

b)

Endemic

c)

Pandemic

d)

Disease

15.

Parathyroid hormone decreases the calcium levels in your blood. True or False?

a)

True

b)

False

16.

Less Calcium blocks more sodium channels. How does this affect the body? Select all that apply (SATA).

a)

Chvostek and trousseau sign

b)

Increases neuromuscular activity

c)

Convulsions

d)

Dehydration

e)

Hypoactive reflexes

17.

Manifestations of hyponatremia include... SATA

a)

Decreased extracellular fluid osmotic pressure

b)

Causes are diuretics

c)

Confusion

d)

Renal dysfunction

18.

Hyperkalemia stresses the cardiovascular system leading to lethal arrhythmias and other pathologies T or F

a)

True

b)

False

19.

What are the characteristics of a Type III hypersensitivity response?

a)

Immediate reactions, Ag- AB complex deposited in tissues

b)

IgE mediated- allergic reactions

c)

T cell-mediated reaction- delayed reaction

d)

None of the above

20.

The two main factors that cause autoimmune diseases are age and level of development T or F

a)

F

b)

T

21.

Characteristics of Rheumatoid Arthritis are: SATA

a)

Inflammatory destruction of the synovial membrane

b)

It's a autoimmune disease

c)

Acute disease

d)

Causes inflammation of the joint

22.

Manifestations of somatic death include: (select all that apply)

a)

rigor mortis

b)

an increase in body temperature

c)

putrefaction and pallor mortis

d)

pupil dilation and bloating

e)

slippage or loosening of skin from underlying tissue

23.

Dry gangrene is more likely to occur with disruption of:

a)

oxygen delivery

b)

arterial obstruction

c)

venous obstruction

d)

infection of injured tissue

24.

A 65-year-old female is diagnosed with metastatic breast cancer. She has developed muscle wasting. Which of the following substances would be produced in large quantities to eliminate the tumor cells and cause muscle wasting?

a)

Cytokines

b)

Interleukins

c)

Tumor Necrosis Factor

d)

Macrophages

25.

The nurse is assessing a patient with a diagnosis of inflammation. The nurse would expect to find which of the following signs and symptoms consistent with acute inflammation. (select all that apply)

a)

Rubor

b)

Loss of function

c)

Heat

d)

Pain

e)

Edema

26.

A 12-year-old male is fighting with another child when he receives a puncture wound from a pencil. The school nurse cleans and bandages the wound. After about 1 week, the wound would be in which phase of healing?

a)

Debridement

b)

Primary intention

c)

Resolution

d)

Maturation

27.

A 25-year-old female experiences a headache and takes aspirin for relief. A nurse recalls aspirin relieves the headache by:

a)

Decreasing leukotriene production

b)

Increasing histamine release

c)

Decreasing prostaglandin production

d)

Increasing platelet-activating factor

28.

A 54-year-old male with a long history of smoking complains of excessive tiredness, shortness of breath, and overall ill feelings. Lab results reveal decreased pH, increased CO2, and normal bicarbonate ion. These findings help to confirm the diagnosis of:

a)

Respiratory acidosis

b)

Metabolic acidosis

c)

Respiratory alkalosis

d)

Metabolic alkalosis

29.

A 60-year-old male with a 30-year history of smoking is diagnosed with a hormone-secreting lung tumor. Further testing indicates that the tumor secretes ADH. Which of the following assessment findings should the nurse expect? (Select all that apply.)

a)

Weakness

b)

Confusion

c)

Nausea

d)

Muscle twitching

e)

Increased ICP

30.

Which of the following patients is the most at risk for developing hypernatremia? A patient with:

a)

Dehydration

b)

Vomiting

c)

Diuretic use

d)

Hypoaldosteronism

31.

A nurse is reviewing lab reports. The nurse recalls blood plasma is located in which of the following fluid compartments?

a)

ICF

b)

ECF

c)

Interstitial fluid

d)

Intravascular fluid

32.

ADH is made in the hypothalamus and is released by the anterior pituitary gland when blood osmolarity goes up.

a)

True

b)

False

33.

Edema is caused by an increase in forces favoring fluid filtration from the capillaries.

a)

True

b)

False

34.

What type of exudate is a blister?

a)

Fibrinous

b)

Serous

c)

Purulent

d)

Ulceration

35.

If someone is experiencing hypotonic hyponatremia what would be the best way to replace fluids?

a)

Give them a gallon of water to replace excessive dehydration

b)

Give them a gatorade to replace the electrolytes

c)

Give them a hypotonic solution

d)

Have them rest and eat plenty of protein

36.

The primary actions of the complement cascade include all EXCEPT..

a)

Increased vascular permeability

b)

Vasodilation

c)

Vasoconstriction

d)

Chemotaxis

37.

What is a manifestation of a patient having a systemic response to an infection?

a)

Redness

b)

Warm arm

c)

Pain

d)

Fever

38.

A patient was admitted to the hospital after contracting HPV. Upon biopsy of the cervical tissue the doctor notices misshapen cells on the culture. What type of cellular adaptation is this?

a)

Hypertrophy

b)

Atrophy

c)

Metaplasia

d)

Dysplasia

39.

Joe comes into the ED after having an allergic reaction to peanuts. What type of hypersensitivity reaction is this?

a)

Type I

b)

Type II

c)

Type III

d)

Type IV

40.

This type of immunoglobulin is found in saliva, tears, colostrum and mucus. It prevents antigens from entering the body.

a)

IgM

b)

IgA

c)

IgD

d)

IgE

41.

T cells are responsible for cell-mediated immunity (T or F)

a)

True

b)

False

42.

Joe had a heart attack two years ago and he experienced additional damage to his heart once blood flow had been restored. What is this phenomenon called?

a)

Ischemia

b)

Myocardial Infarction

c)

Reperfusion Injury

d)

Hypertension

43.

What is the name of the process the mast cell initiates for the inflammatory response to happen?

a)

Leukocytosis

b)

Chemotaxis

c)

Degranulation

d)

Apoptosis

44.

What type of cell is the first responder to an injury and you would see primarily during acute inflammation?

a)

Eosinophils

b)

Neutrophils

c)

Leukotrienes

d)

Histamine

45.

The slower response results in vessel remodeling and includes profound changes in the cellular architecture. (T or F)

a)

True

b)

False

46.

Factor XII (Hageman’s factor) promotes formation of what?

a)

antigens/antibodies

b)

classic complements

c)

bradykinin

d)

extrinsic pathway

47.

__________ cells tolerate hypoxia for only a few minutes

a)

Skin

b)

Renal

c)

Neuron and glial

d)

Hepatic

48.

Hydrostatic pressure can be described as...

a)

Water moving across the capillary membrane by filtration

b)

Proteins such as albumin

c)

Pulling factors

d)

Assisting electrons to flow down a gradient

49.

Secretion of ADH is stimulated by:

a)

Increased plasma osmolarity

b)

Increased serum potassium

c)

Decreased renal blood flow

d)

Intracellular dehydration

50.

Which statement indicates a correct understanding of antibodies? The most abundant class of antibodies in the serum is:

a)

IgG

b)

IgM

c)

IgA

d)

IgE

51.

Blood vessel walls divide intracellular fluid from blood plasma (True or False)

a)

True

b)

False

52.

Which of the following electrolytes are found in high concentrations in the extracellular fluid? (Select all that apply)

a)
  1. Sodium (Na⁺)

b)
  1. Magnesium (Mg²⁺)

c)
  1. Potassium (K⁺)

d)
  1. Calcium (Ca²⁺)

e)
  1. Chloride (Cl⁻)

53.

B cells are responsible for cell-mediated immunity that is mediated by circulating antibodies (True or False)

a)

True

b)

False

54.

Which of the following statements best describes the actions of vasoactive amines during the early stages of inflammation?

a)

Histamine and serotonin are released later in the inflammatory response and primarily decrease blood flow

b)

Histamine, released from mast cells, increases capillary permeability by causing endothelial cell retraction and can also cause vasodilation

c)

Serotonin and histamine both inhibit vascular permeability to limit swelling

d)

Platelets, released from mast cells, cause temporary vasoconstriction and venule dilation

55.

Primary cell types that produce mediators during acute inflammation are all except...

a)

Macrophages

b)

Dendritic cells

c)

Natural killer cells

d)

Mast cells

56.

The principal systemic effects of inflammation are fever and increases in levels of circulating... (SATA)

a)

leukocytes

b)

mast cells

c)

plasma proteins

d)

serotonin

e)

Bradykinin

57.

Alloimmunity is the immune system’s reaction against antigens on the tissues of other members of the same species (T and F)

a)

True

b)

False

58.

Cytotoxic B cells mistakenly attack the body’s own cells.

a)

True

b)

False

59.

Cellular tolerance to hypoxia may involve all except

a)

reduction in the metabolic rate

b)

increased extraction of oxygen from the blood and surrounding tissues

c)

adaptations of enzymes to allow metabolism at low partial pressures of oxygen

d)

autodigestion of intracellular structures

60.

The most common types of blunt-force injuries include (SATA)

a)

motor vehicle accidents

b)

assaults

c)

falls

d)

sports injuries

e)

strangulation

61.

What hormone provides a means of controlling water output independently of sodium?

a)

Aldosterone

b)

Parathyroid hormone

c)

Antidiuretic hormone

d)

Calcitonin

62.

Changes in urine volume are usually linked to adjustments in potassium reabsorption (Tor F)

a)

True

b)

False

63.

When planning care for a cardiac patient, the nurse knows that in response to an increased workload, cardiac myocardial cells will _______.

a)

Hypertrophy

b)

Atrophy

c)

Undergo apoptosis

d)

Remain unchanged

64.

What Pathophysiological concept should the health professional consider when developing a plan of care for a patient with myocardial ischemia?

a)

There is a lack of oxygen reaching the myocardium, but the supply of glucose is adequate.

b)

There is a lack of glucose reaching the myocardium, but the supply of oxygen is adequate.

c)

There is a decrease in the amount of oxygen and glucose reaching the myocardium

d)

There us a complete lack of both oxygen and glucose reaching the myocardium

65.

Potassium imbalances are the most dangerous of all electrolyte imbalances. (T or F)

a)

True

b)

False

66.

The increased intracellular concentration of _______ may inappropriately activate a number of enzymes with potentially damaging effects.

a)

Calcium

b)

Sodium

c)

Potassium

d)

Magnesium

67.

Which of the following statements accurately describes Type I hypersensitivity reactions? (Select all that apply)

a)

They are mediated by IgE antibodies that trigger mast cell degranulation

b)

They typically occur hours to days after antigen exposure

c)

Common allergens include pollens, molds, foods, and animal dander

d)

Tissues rich in mast cells, such as the skin, GI tract, and respiratory tract, are often affected

e)

The route of allergen entry can influence whether the reaction is local or systemic

68.

Signs and symptoms of Hypercalcemia (SATA)

a)

Nerves fire more easily

b)

Lethargy

c)

Tetanus

d)

Stupor

e)

Muscle weakness

69.

The important chemical buffer systems include all the following except…

a)

The protein system

b)

The carbonic acid-bicarbonate system

c)

The phosphate system

d)

The calcium system

70.

When an patient asks the nurse about the purpose of the inflammatory process, how should the nurse respond?

a)

To provide specific responses toward antigens

b)

To lyse cell membranes of microorganisms

c)

To prevent infection of the injured tissue

d)

To create immunity against subsequent tissue injury

71.

(T or F) Type II hypersensitivity reactions are mediated by IgG or IgM antibodies that bind to antigens on cell surfaces, leading to tissue-specific cytotoxic effects.

a)

true

b)

false

72.

A patient experiences a rapid rise in extracellular potassium levels due to a crush injury. Which of the following statements correctly describes the effects on nerve and muscle cells?

a)

The sudden increase in potassium hyperpolarizes the cells, making them less excitable.

b)

Rapid extracellular potassium rise initially depolarizes cells, increasing excitability, but then slows repolarization and reduces excitability.

c)

Slow potassium infusion produces immediate cardiac arrest.

d)

Hyperkalemia has no effect on the resting membrane potential of cells.

73.

All are signs and symptoms of Lupus except…

a)

Butterfly rash

b)

Pericarditis

c)

Nonerosive arthritis

d)

Photosensitivity

74.

If the immune system cannot perform functions properly, a variety of illnesses may result—including hypersensitivity reactions and autoimmune disorders (T or F)

a)

True

b)

False

75.

John, a 60-year-old man with severe chronic obstructive pulmonary disease (COPD), presented to the emergency department with worsening shortness of breath. Arterial blood gas analysis revealed significant hypoxemia, highlighting the chronic hypoxic state experienced by his cells due to impaired gas exchange in the lungs, resulting in hypoxic cell injury and contributing to the progression of his COPD. Which of the following would be seen in hypoxic cell injury? Select all that apply:

a)

Decreased ATP production

b)

Decreased membrane permeability

c)

Mitochondrial dysfunction and increased reactive oxygen species (ROS)

d)

Decreased intracellular sodium

e)

Increased intracellular sodium

76.

What is the main difference between B cells and T cells?

a)

B cells produce antibodies, while T cells kill infected cells directly.

b)

B cells are part of the innate immune system, while T cells are part of the adaptive immune system.

c)

B cells are found only in the spleen, while T cells are found throughout the body.

d)

B cells can live for many years, while T cells live for a few days.

77.

The cells/signaling molecules involved in the initiation of the inflammatory response are ___, while cells/signaling molecules that initiate dilation of blood vessels are ___.

a)

phagocytes and lysozymes

b)

macrophages/chemokines; mast cells/histamines

c)

dendritic cells/interferons; mast cells/lysozymes

d)

mast cells/ histamines; phagocytes

78.

Which cellular response mechanism results in an increase in the number of cells?

a)

Atrophy

b)

Hypertrophy

c)

Hyperplasia

d)

Metaplasia