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Final Exam Review- MDL 328A

Total questions: 35

Worksheet time: 18mins

Name
Class
Date
1.

What is the principle of the reagent strip test for urine protein?

a)

Copper reduction

b)

An enzymatic reaction

c)

The toluidine reaction

d)

Protein error of indicators

2.

The intensity of colour produced in the Biuret reaction depends most on which of the following?

a)

Molecular weight of the protein

b)

Which protein are present

c)

The number of peptide bonds

d)

The A/G ratio

3.

What is the result to the rate of an enzymatic reaction with increase in temperature from 25oC to 35oC?

a)

Half

b)

Double

c)

Remains the same

d)

Decreases

4.

In monoclonal gammopathy, a large increase in which protein fraction is excepted on serum protein electrophoresis?

a)

Albumin

b)

Alpha 1

c)

Alpha 2

d)

Gamma

5.

To what major class of enzyme does amylase belong?

a)

Hydrolase

b)

Oxidoreductase

c)

Transferase

d)

Isomerase

6.

Which lipoprotein carries most of the endogenous triglycerides?

a)

LDL

b)

VLDL

c)

HDL

d)

Chylomicrons

7.

LD catalyzes the conversion of lactic acid to which substance?

a)

Pyruvate

b)

Citric acid

c)

Oxaloacetic acid

d)

Malic acid

8.

Which isoenzyme of CK has the slowest electrophoretic mobility at pH 8.6?

a)

MM

b)

MB

c)

BB

d)

Macro CK

9.

How many subunits are LD isoenzymes composed of?

a)

1

b)

2

c)

3

d)

4

10.

Which of the following apolipoproteins is essential for chylomicron formation?

a)

B-100

b)

B-48

c)

CII

d)

AI

11.

Which protein listed migrates in the beta region at pH 8.6?

a)

Haptoglobin

b)

Anti-trypsin

c)

IgG

d)

Transferrin

12.

The enzyme that is increased significantly during pernicious anemia is:

a)

LD

b)

CK

c)

AST

d)

ALP

13.

Which 2 molecules combine to form ketone bodies?

a)

Acetyl CoA and a ketoacid

b)

Acetyl CoA and a fatty acid

c)

Acetyl CoA and glycerol

d)

2 Acetyl CoA

14.

Which urine protein result would correlate best with a patient with nephrotic syndrome?

a)
Low levels of protein in urine
b)
Normal levels of protein in urine
c)
High levels of glucose in urine
d)
High levels of protein, particularly albumin, in urine.
15.

The lipoprotein that contains the greatest amount of protein is called:

a)
High-density lipoprotein (HDL)
b)
Intermediate-density lipoprotein (IDL)
c)
Low-density lipoprotein (LDL)
d)
Very low-density lipoprotein (VLDL)
16.

The protein component of a lipoprotein is referred to as:

a)

Terpene

b)

Apolipoprotein

c)

Prostaglandin

d)

Phospholipid

17.

Which protein is found in serum, CSF, interstitial fluid, and amniotic fluid?

a)

Transferrin

b)

Marcoglobulin

c)

Albumin

d)

Beta-globulin

18.

Which enzyme can be estimated in both serum and urine?

a)

ALP

b)

LD

c)

CK

d)

AMY

19.

A type of cancer diagnosed in part by ID of a paraprotein in blood or urine is:

a)

Multiple myeloma

b)

Bence-Jones proteins

c)

Hypogammaglobulinemia

d)

Wilson disease

20.

Which term describes a condition that shows a split in the albumin band on protein electrophoresis?

a)

Analbuminemia

b)

Anodic albuminemia

c)

Prealbuminemia

d)

Bisalbuminemia

21.

At pH 8.6, what causes the cathodal movement of gamma-globulins?

a)

Endosmosis

b)

Wick flow

c)

A net positive charge

d)

Cathodal sample application

22.

Which is the most sensitive marker for alcoholic liver disease?

a)

GLD

b)

ALT

c)

AST

d)

GGT

23.

Which protein is most responsible for maintaining osmotic pressure?

a)
Keratin
b)
Collagen
c)
Albumin
d)
Hemoglobin
24.

Which protein has the highest dye-binding capacity?

a)

Albumin

b)

Alpha globulin

c)

Beta globulin

d)

Gamma globulin

25.

What is the reference range for serum albumin?

a)

3.5-5.5 g/L

b)

35-55 g/L

c)

38-50 mmol/L

d)

35-55 mg/L

26.

The routine Biuret method is NOT used for urine or CSF protein determinations due to which of the following reasons?

a)

Absorbance shifts

b)

Interferences present in sample

c)

Precipitation of protein

d)

Poor sensitivity

27.

Exudate fluid would most likely be formed as a result of which of the following?

a)

Infection

b)

Blocked lymphatic drainage

c)

Disturbance of cardiac function

d)

Increased hydrostatic pressure

28.

Under specified conditions of pH and temperature control, which of the following statements describes the Katal unit?

a)

The time require to utilize one mole of substrate

b)

Utilization of 1 mole of substrate per second

c)

Milligrams of product formed per hour

d)

Utilization of 1 micromole of substrate per minute

29.

When analytical procedures use enzymes as reagents, which statement is correct?

a)

The timing of the final reading is usually not critical

b)

Excess substrate is required to ensure zero order kinetics

c)

Readings must be taken at frequent intervals

d)

Readings must be taken during maximum and constant rate period

30.

What best describes triglycerides?

a)

Anhydrides of glycerol and fatty acids

b)

Chain of amino acids

c)

Utilized for steroid production

d)

Hydrophilic

31.

Which enzyme is most specific for diagnosing acute pancreatitis?

a)

AMY

b)

AST

c)

LD

d)

CK

32.

Which protein fraction is most likely to increase in nephrotic syndrome?

a)

Gamma globulin

b)

Beta globulin

c)

Alpha 2 globulin

d)

Albumin

33.

Which enzyme is commonly used as a marker for myocardial infarction?

a)

LDH

b)

ALP

c)

CK-MB

d)

AMY

34.

Which lipoprotein is primarily responsible for transporting cholesterol from tissues to the liver?

a)

VLDL

b)

HDL

c)

LDL

d)

Chylomicrons

35.

Which lipoprotein is primarily responsible for transporting dietary triglycerides?

a)

Chylomicrons

b)

VLDL

c)

LDL

d)

HDL