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kassim Hafiz Hope Quiz on Transamination, Deamination, and Urea Cycle

Total questions: 21

Worksheet time: 54mins

Name
Class
Date
1.

Which enzyme catalyzes transamination reactions?

a)

Aspartate transaminase (AST)

b)

Glutamate dehydrogenase

c)

Carbamoyl phosphate synthetase

d)

Urease

2.

What coenzyme is required for transamination reactions?

a)

FAD

b)

NAD+

c)

Pyridoxal phosphate (PLP)

d)

Coenzyme Q

3.

In which organ do most transamination reactions occur?

a)

Brain

b)

Liver

c)

Heart

d)

Lungs

4.

In which part of the cell do transamination reactions occur?

a)

Nucleus

b)

Cytosol

c)

Mitochondria

d)

Ribosome

5.

Which amino acid does not undergo transamination?

a)

Lysine

b)

Alanine

c)

Glutamate

d)

Aspartate

6.

What is the most commonly transaminated amino acid?

a)

Glutamate

b)

Glycine

c)

Valine

d)

Leucine

7.

What are the two types of deamination?

a)

Oxidative and Non-oxidative

b)

Hydrolytic and Transaminative

c)

Reductive and Oxidative

d)

None of the above

8.

Which enzyme is involved in oxidative deamination?

a)

Glutamate dehydrogenase

b)

Aspartate transaminase

c)

Urease

d)

Pyruvate kinase

9.

Which enzyme is involved in non-oxidative deamination?

a)

Serine dehydratase

b)

Glutamate dehydrogenase

c)

Carbamoyl phosphate synthetase

d)

Urease

10.

Which amino acid does not undergo deamination?

a)

Serine

b)

Proline

c)

Alanine

d)

Glutamate

11.

Which enzyme catalyzes the first reaction of the urea cycle?

a)

Aspartate transaminase

b)

Carbamoyl phosphate synthetase I (CPS-I)

c)

Argininosuccinate synthetase

d)

Ornithine transcarbamoylase

12.

What is the end product of the urea cycle?

a)

Ammonia

b)

Urea

c)

Glutamate

d)

Aspartate

13.

How many steps are involved in the urea cycle?

a)

3

b)

4

c)

5

d)

6

14.

Where do the first two steps (step 1 ,2) of the urea cycle occur?

a)

Cytosol

b)

Mitochondria

c)

Endoplasmic reticulum

d)

Golgi apparatus

15.

Where do the remaining steps (3,4,5) of the urea cycle occur?

a)

Cytosol

b)

Mitochondria

c)

Endoplasmic reticulum

d)

Nucleus

16.

What is hyperammonemia?

a)

Excess urea in the blood

b)

Excess ammonia in the blood

c)

Excess glucose in the blood

d)

None of the above

17.

What is the transportable form of ammonia?

a)

Fructose

b)

Glutamine

c)

Glucose

d)

Non of the above

18.

Why is ammonia not transported in free form in the blood?

a)

It is highly soluble in blood.

b)

It is toxic to the body.

c)

It is poorly reactive in blood.

d)

It is too large to travel freely.

19.

What is the significance of carbamoyl phosphate in the urea cycle?

a)

It is an end product of the urea cycle.

b)

It initiates the cycle by combining with ornithine.

c)

It transports ammonia in the blood.

d)

It converts ammonia to glutamine.

20.

Which enzyme move ornithine from cytosol into mitochondria ?

a)

Ornithine translocase

b)

Argininosuccinate lyase

c)

Citrulline translocase

d)

Urease

21.

Who are the donors of the nitrogen atom represented in red and green in urea structure shown above?

a)

Ammonia and amino acid(aspartate)

b)

Lysine and benzene

c)

Glucose and fructose

d)

All of the above

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