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Unit: 7 DNA, RNA, and Mutations Test Review

Total questions: 70

Worksheet time: 42mins

Name
Class
Date
1.

DNA is an acronym for _____

a)

Diphosphorus Nucleic Acid

b)

Ribose Nucleic Acid

c)

Deoxyribonucleic Acid

d)

Deoxyribonucleic Acetate

2.

A nucleotide is composed of

a)

A phosphate, sugar and nitrogenous base

b)

A protein, protein and Guanine

c)

A phosphate, Adenine, and nitrogenous base

d)

A protein, Adenine and nitrogenous base

3.

Which of the following is a base pair?

a)

Adenine - Cytosine

b)

Cytosine - Thymine

c)

Deoxyribose - Cytosine

d)

Cytosine - Guanine

4.

The weak bonds between base pairs is a ___

a)

Covalent Bond

b)

Polar Bond

c)

Non Polar Bond

d)

Hydrogen

5.
Which of the following best describes a DNA molecule?
a)
double helix
b)
contains ribose
c)
made of amino acids
d)
contains Uracil
6.
Adenine bonds with ______________.
a)
Guanine
b)
Thymine
c)
Cytosine
d)
Adenine
7.
What are the 4 nitrogen bases?
a)
adenine, thymine, cytoplasm, and guanine
b)
adenine, thymine cytosine, and guanine
c)
adenine, thymine, cytosine, and gylcerol
d)
adenine, thymine, cytosine, and glucose
8.
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
9.
Which macromolecule is shown?
a)
lipid
b)
protein
c)
nucleic acid
d)
carbohydrate
10.
Nitrogenous bases are joined by which type of bond?
a)
polar bonds
b)
ionic bonds
c)
covalent bonds
d)
hydrogen bonds
11.

The enzyme that unwinds and unzips the DNA to prepare for replication is:

a)
helicase
b)
replicase
c)
polymerase
d)
synthase
12.
Which enzyme is responsible for adding nucleotides ("The Builder")?
a)
Topoisomerase
b)
DNA Polymerase
c)
Ligase
d)
Primase
13.

The two strands of DNA are

a)

Parallel: run in the same direction

b)

Antiparallel: run in opposite directions

14.

You are given the DNA strand 5'ATGCTCAGCTGA3'. What is the corresponding DNA strand?

a)

5'UACGAGUCGACU3'

b)

5'TACGAGTCGACT3'

c)

3'UACGAGUCGACU5'

d)

3'TACGAGTCGACT5'

15.

Which is the role of DNA polymerase?

a)

Unwinds the original DNA strand

b)

Lays down RNA primer for new nucleotide bases.

c)

Builds new strands by bringing in new nucleotide bases.

d)

Remove Okazaki fragments for new nucleotides.

16.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

17.

Which letter in the picture below depicts the lagging strand in DNA replication?

a)

Letter A since it is copied from 5' to 3'

b)

Letter A since it is copied from 3' to 5'

c)

Letter B since it is copied from 3' to 5

d)

Letter B since it is copied from 5' to 3'

18.

DNA replication puts down nucleotides ______' to _____' and is said to be ______________________

a)

5, 3, antiparallel

b)

3, 5, antiparallel

c)

5, 3, parallel

d)

3, 5, parallel

19.

During transcription, this type of ribonucleic acid is responsible for copying the DNA and brining it out of the nucleus.

a)

tRNA

b)

mRNA

c)

rRNA

d)

dRNA

20.

Which of the following is the complementary mRNA sequence to this DNA strand: AACTGAA

a)

UUGACUU

b)

TTGACTT

c)

AACTGAA

d)

AACUGAA

21.
What is the term for a three-nucleotide sequence that codes for an amino acid?
a)
base
b)
codon
c)
amine
d)
serine
22.
The process to go from DNA to mRNA is _______
a)
translation
b)
transcription
c)
replication
23.
The process to go from mRNA to a protein is called ____
a)
transcription
b)
rRNA
c)
replication
d)
translation
24.

Which organelle contains rRNA and reads the mRNA to synthesize a protein?

a)

Ribosome

b)

Nucleus

c)

Cytoplasm

d)

Nucleotide

25.

What brings the amino acids to the ribosome to assemble a protein?

a)
mRNA
b)
tRNA
c)
rRNA
d)

DNA

26.

How many nucleotides code for 1 amino acid?

a)

1

b)

2

c)

3

d)

4

27.

What is the location in the cell for translation?

a)

Cytoplasm

b)

Nucleus

c)

Lysosome

d)

Golgi apparatus

28.

What is the amino acid sequence for the following mRNA strand:

AUG-GAC-UAG

(a)  

29.

What is the amino acid sequence for the following mRNA strand:

AGG-UUC-CUG

Write your answer like this: ___-___-___

(a)  

30.

What is the amino acid sequence for the following mRNA strand:

CCA-GAG-UAG

Write your answer like this: ___-___-___

(a)  

31.

Match the following

a)

mRNA

1.

carrying instructions from DNA

b)

tRNA

2.

carries an amino acid

c)

rRNA

3.

the ribsome where proteins are made

32.
Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA
a)
no mutation
b)
substitution
c)
insertion
d)
deletion
33.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.
a)
Substitution
b)
Deletion
c)
Insertion
d)
Inversion
34.
If you are missing or have an extra base  at the end of your mutated DNA . What type of mutation occurred?
a)
Substitution
b)
Frameshift
c)
Duplication 
d)
Insertion
35.
Original: ATC CAT
Mutation: ATC GCAT
What mutation occurred?
a)
deletion
b)
insertion
c)
silent
d)
transverse
36.
A frameshift mutation can occur with either _________ or __________ mutations.
a)
Addition, division
b)
Deletion, substitution
c)
Addition, substitution
d)
Addition, deletion
37.
What type of chromosomal mutation is this?
a)
Inversion
b)
Translocation
c)
Deletion
d)
Duplication
38.
Identify the SUBSTITUTION mutation from the following DNA sequence: 
ATG CCA AAT
a)
ATG TCA AAT
b)
ATG CCT AAA T
c)
ATC CA  AT
d)
ATG CCA AAT
39.

What describes a change in the DNA sequence?

a)

Transcription

b)

Translation

c)

DNA replication

d)

Mutation

e)

Apoptosis

40.

What type of mutation involves substituting a DNA base with a different base?

a)

point mutation

b)

frameshift mutation

c)

silent mutation

d)

chromosomal mutation

41.

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC GAC TTG AAT

What type of mutation has occurred?

a)

Chromosomal mutation

b)

Point mutation

c)

Frameshift mutation

d)

No mutation occurred

42.

What are considered "negative" mutations?

a)

mutations in the DNA sequence that changes the resulting protein and harms the organism

b)

mutations in the DNA sequence that changes the resulting protein and benefits the organism

c)

mutations in the DNA sequence that produces the same protein

d)

all mutations are considered bad and harm the organisms

43.

What are considered "positive" mutations?

a)

mutations in the DNA sequence that changes the resulting protein and harms the organism

b)

mutations in the DNA sequence that changes the resulting protein and benefits the organism

c)

mutations in the DNA sequence that produces the same protein

d)

all mutations are considered bad and harm the organisms

44.

Causes children to age rapidly, hair loss, and wrinkles

a)

Sickle cell anemia

b)

Alzheimer's disease

c)

Progeria

d)

Cystic fibrosis

45.

Changes in the brain that leads to memory loss, brain shrinkage, delusions, and the loss of ability to perform daily tasks.

a)

Alzheimer's disease

b)

Down syndrome

c)

Sickle cell anemia

d)

Muscular dystrophy

46.

Have a full or partial extra copy of chromosome 21, also known as trisomy 21.

a)

Sickle cell anemia

b)

Progeria

c)

Cystic fibrosis

d)

Down syndrome

47.

Inherited red blood cell disorder, hemoglobin in the blood is abnormal leading to a sickle shape.

a)

Down syndrome

b)

Sickle cell anemia

c)

Progeria

d)

Cystic fibrosis

48.

Progressive genetic disorder that affects the lungs and digestive tract with thick, sticky mucus.

a)

Cystic fibrosis

b)

Sickle cell anemia

c)

Muscular dystrophy

d)

Progeria

49.

Progressive muscle weakness, primarily in males, frequent falls and trouble walking.

a)

Sickle cell anemia

b)

Muscular dystrophy

c)

Progeria

d)

Alzheimer's disease

50.

What is A?

a)

Helicase

b)

Leading strand

c)

Lagging strand

d)

Primase

51.

What is B?

a)

Lagging strand

b)

Leading strand

c)

Helicase

d)

DNA Polymerase

52.

What is C?

a)

DNA polymerase

b)

Primase

c)

RNA primer

d)

Helicase

53.

What is D?

a)

RNA primer

b)

Primase

c)

Helicase

d)

DNA polymerase

54.

What is E?

a)

Helicase

b)

DNA polymerase

c)

RNA primer

d)

Lagging strand

55.

What is F?

a)

Primase

b)

Leading strand

c)

Lagging strand

d)

Helicase

56.

What is 1?

a)

Amino acid

b)

Codon

c)

Ribosome

57.

What is 2?

a)

Amino acid

b)

Codon

c)

Ribosome

58.

What is 3?

a)

Amino acid

b)

Codon

c)

Ribosome

59.

What does a karyotype diagram show?

a)

Diploid number of chromosomes

b)

Haploid number of chromosomes

60.

Who is credited with first discovering DNA?

a)

Franklin

b)

Chargaff

c)

Meischer

d)

Levene

e)

Watson and Crick

61.

A piece of a chromosome is lost

a)

deletion

b)

duplication

c)

inversion

d)

translocation

62.

A piece of a chromosome is copied and remains within the chromosome

a)

deletion

b)

duplication

c)

inversion

d)

translocation

63.

A piece of the chromosome detches, turns 180 degrees, and reattaches

a)

deletion

b)

duplication

c)

inversion

d)

translocation

64.

A piece of one chromosome detaches and reattaches to a different chromosome

a)

deletion

b)

duplication

c)

inversion

d)

translocation

65.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

66.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

67.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

68.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

69.

What is a clone?

a)
A clone is a hybrid organism created from two different species.
b)
A clone is a genetically identical copy of an organism or cell.
c)
A clone is a type of virus that infects cells.
d)
A clone is a process of natural selection in evolution.
70.

What is an operon?

a)
An operon is a functional unit of DNA containing a cluster of genes controlled by a single promoter.
b)
A single gene that codes for a protein.
c)
A type of RNA molecule involved in translation.
d)
A regulatory protein that binds to DNA.