WorksheetsCellular Injury and Adaptation Quiz
Total questions: 62
Worksheet time: 31mins
According to the sources, what is the primary mechanism by which cellular injury occurs in hypoxia?
Accumulation of extracellular fluid
Failure of ATP-dependent pumps
Increased production of glycogen
Decreased activity of reactive oxygen species
A nurse is caring for a neonate shortly after birth. The nurse understands that the closure of the foramen ovale is primarily due to:
Contraction of Wharton's Jelly
Increased pulmonary vascular resistance
Low pressure within the left atrium
Pressure changes in the atria
Which type of cellular adaptation is characterized by a decrease in cell size due to decreased functional demand?
Hyperplasia
Metaplasia
Atrophy
Hypertrophy
According to the sources, which type of cellular change is described as disorderly appearance and growth of cells with abnormal variations in size, shape, and arrangement, and is NOT a true adaptive process?
Metaplasia
Dysplasia
Atrophy
Hypertrophy
Which of the following is listed as the number one cause of cell death in the sources?
Ischemia
Reperfusion injury
Hypoxia
Chemical agents
A nurse is educating a student about irreversible cell injury. The nurse states that critically damaged plasma, mitochondrial, and lysosomal membranes lead to cell death. This damage can be caused by:
Glycogen depletion
Lactate production
Reactive Oxygen Species (ROS)
ATP accumulation
According to the sources, reperfusion injury can involve which of the following mechanisms?
Decreased ROS formation
Resolution of inflammation
Calcium overload damaging mitochondria
Decreased oxidative stress
Which statement accurately contrasts necrosis and apoptosis according to the sources?
Necrosis involves cell shrinkage, while apoptosis involves cell swelling.
Necrosis causes inflammation, while apoptosis typically does not.
Necrosis is programmed cell death, while apoptosis is random cell death.
Necrosis results in the formation of apoptotic bodies, while apoptosis results in cell bursting.
A patient is diagnosed with cystitis. Which clinical manifestation is associated with cystitis?
Fever
CVA Tenderness
Dysuria
Anorexia
Which of the following is listed as the most common cause of Urinary Tract Infections (UTIs)?
Staphylococcus saprophyticus
E. coli
Schistosomiasis
Pseudomonas aeruginosa
A nurse is assessing an older adult patient for a UTI. Which atypical presentation might be observed?
High fever and chills
CVA tenderness
New onset confusion
Vomiting and diarrhea
Pelvic Inflammatory Disease (PID) is most commonly caused by which pathogens?
E. coli and Staphylococcus saprophyticus
Streptococcus pneumoniae and Neisseria meningitidis
Gonorrhea and chlamydia
Enteroviruses and herpes simplex
According to the sources, a hallmark sign of infection seen in Pelvic Inflammatory Disease (PID) is:
Unilateral abdominal tenderness
Increased WBCs
Vaginal douching
Decreased C-reactive protein (CRP)
Which complication is listed as a potential outcome of Pelvic Inflammatory Disease (PID)?
Reduced risk of ectopic pregnancy
Infertility due to scar tissue
Decreased chronic pelvic pain
Easier descent of the egg
According to the sources, what is the primary mechanism by which the RAAS system increases blood pressure?
Decreasing blood volume and vascular resistance
Increasing heart rate and stroke volume
Increasing blood volume and vascular resistance
Decreasing systemic vascular resistance (SVR)
Hypertension is often referred to as the "silent killer" because:
It only affects a small percentage of the population.
Symptoms are often not noticeable until damage is done.
It is easily cured with lifestyle modifications.
It is always related to a specific cause.
What percentage of hypertension cases are classified as Primary HTN, having no clearly identifiable etiology?
10%
30%
60%
90%
Which of the following is listed as a modifiable risk factor for hypertension?
Increased age
Assigned male at birth
Family history
Unhealthy diet
According to the sources, a diagnosis of hypertension requires elevated blood pressure readings on how many separate occasions?
One
Two
Three
Four
Preeclampsia is diagnosed after 20 weeks gestation with new onset hypertension AND which additional factor(s)?
Bradycardia and hypotension
Proteinuria factors
Increased heart rate
Elevated blood sugar
Which condition in pregnancy is characterized by Hemolysis, Elevated Liver enzymes, and Low Platelets?
Gestational HTN
Chronic HTN
Eclampsia
HELLP
According to the sources, what is considered the #1 treatment for severe preeclampsia?
Antihypertensives
Seizure prophylaxis
Delivery of the placenta
Aspirin
According to the sources, what percentage of pulmonary emboli originate from Deep Vein Thrombosis (DVT) in the lower extremities?
30%
60%
90%
10%
Virchow's triad, which increases the risk for thrombus formation leading to a Pulmonary Embolism, includes:
Hypotension, hypercoagulable conditions, and vessel wall injury
Vessel wall injury, hypercoagulable conditions, and circulatory stasis
Circulatory stasis, vasodilation, and vessel wall injury
Hypercoagulable conditions, increased blood flow, and vessel wall injury
According to the sources, which symptom is an assessment finding associated with Pulmonary Embolism?
Decreased respiratory rate
Chest pain
Increased SpO2
Feeling of euphoria
Which diagnostic test is considered the diagnostic test for Pulmonary Embolism according to the sources?
Chest x-ray
Arterial Blood Gas (ABG)
Elevated D-dimer
CT angiogram
Asthma is classified as which type of lung disease?
Restrictive
Obstructive
Infectious
Vascular
The three mechanisms involved in asthma are hyperresponsiveness, bronchoconstriction, and reversible airflow obstruction. These occur in the:
Alveoli
Pleural space
Bronchial mucosa
Pulmonary capillaries
According to the sources, which cells degranulate in the early response of asthma pathophysiology, releasing inflammatory mediators like histamine?
Eosinophils
Mast cells
Leukocytes
Macrophages
The late response in asthma pathophysiology, occurring hours after initial allergen exposure, involves the recruitment of leukocytes and the synthesis of which mediator that causes prolonged smooth muscle contraction?
Histamine
Prostaglandin
Leukotriene
Serotonin
Which finding is the most common clinical manifestation of asthma listed?
Inspiratory wheezing
Non-productive cough
Bradycardia
Hypotension
In the Asthma Action Plan, a peak flow meter reading that is 80% or more of the personal best indicates the patient is in which zone?
Red Zone
Yellow Zone
Green Zone
Orange Zone
Bronchiolitis primarily affects which age group?
Neonates (birth-1 month)
Infants 3-6 months old
Toddlers (1-3 years old)
School-aged children (6-12 years old)
According to the sources, bronchiolitis is usually secondary to which cause?
Autoimmune disorders
Congenital heart defects
Infectious agents like RSV
Environmental pollutants
The pathophysiology of bronchiolitis involves inflammation and swelling deep in the lungs, leading to mucus buildup and resulting in:
Increased gas exchange and improved oxygenation
Decreased airway resistance and increased airflow
Atelectasis and air-trapping/hyperinflation
Bronchodilation and decreased mucus production
According to the sources, why does a small amount of inflammation cause drastic changes in infants with bronchiolitis?
Infants have more developed immune systems.
Infants have short and smaller airways.
Infants are obligate mouth breathers.
Infants have larger lung capacity.
What is the recommended method for treating mucus buildup in infants with bronchiolitis according to the sources?
Albuterol nebulizers
Oral antibiotics
Nasal or oral suctioning
Intubation
A seizure that affects both sides of the brain at the same time is classified as:
Focal seizure
Partial seizure
Generalized seizure
Simple partial seizure
According to the sources, what is the definition of status epilepticus?
A seizure lasting less than 5 minutes
A subjective sense of impending seizure
A seizure that lasts longer than 5 minutes or more than 1 seizure within a 5-minute period without return to normal LOC
The period immediately following a seizure
Which type of generalized seizure is characterized by a sudden, brief loss of consciousness, often presenting as staring or daydreaming?
Tonic-clonic
Absence
Myoclonic
Atonic
Which type of focal seizure involves no change in the patient's level of consciousness?
Complex
Simple
Secondarily generalized
Atonic
According to the sources, febrile seizures are primarily seen between what ages?
Birth - 6 months
6 months - 5 years old
5 years old - adolescence
Adolescence - adulthood
Intracranial pressure (ICP) is exerted by the contents of the cranium, which includes:
Brain matter, CSF, and blood
Bone, meninges, and blood
CSF, bone, and brain matter
Brain matter, blood, and bone
According to the sources, what is the earliest sign of increased intracranial pressure (ICP)?
Vomiting
Headache
Seizures
Change in the patient's level of consciousness (LOC)
Cushing's Triad, a late sign of increased ICP, includes:
Increased SBP/widened pulse pressure + increased pulse + altered respirations
Decreased SBP/narrowed pulse pressure + decreased pulse + altered respirations
Increased SBP/widened pulse pressure + decreased pulse + altered respirations
Decreased SBP/narrowed pulse pressure + increased pulse + altered respirations
According to the sources, which finding is specific to increased ICP in infants?
Increased SBP
Decreased pulse
High-pitched cry
Altered respirations
Meningitis is defined as inflammation or infection of the:
Brain tissue
Spinal cord
Meninges and subarachnoid spaces
Ventricles of the brain
According to the sources, which pathogen is the most common cause of bacterial meningitis in adults?
Neisseria meningitidis
E. coli
Group B- beta hemolytic streptococci
Streptococcus pneumoniae
A nurse is assessing a patient with suspected meningitis. Which sign indicates meningeal irritation?
Petechial rash
Decreased LOC
Fever
Nuchal rigidity
A lumbar puncture is performed on a patient with suspected meningitis. Which finding in the CSF analysis would support a diagnosis of bacterial meningitis?
Low WBCs, high glucose, low protein
High WBCs/neutrophils, low glucose, high protein
Normal WBCs, normal glucose, normal protein
Low WBCs/lymphocytes, high glucose, low protein
What percentage of the body weight in adults is comprised of fluid?
40%
50%
60%
70%
According to the sources, when fluid moves from the intravascular space to a 'third' space where it cannot be used for metabolic processes or perfusion, this is called:
Intracellular accumulation
Cellular swelling
Third spacing
Hypervolemia
Edema is the excessive accumulation of fluid within which space?
Intracellular space
Intravascular space
Peritoneal cavity
Interstitial space
Which of the following can cause a decrease in capillary oncotic pressure, leading to edema?
CHF
Renal failure
Malnutrition
Inflammation
Which vital sign change is associated with hypovolemia?
Increased BP
Decreased HR
Increased HR
Bounding pulses
According to the sources, a pediatric sign of hypovolemia is:
Increased weight
Bulging fontanelles
Sunken fontanelles
Warm extremities
Which clinical manifestation is characteristic of hypervolemia?
Decreased BP
Dry mucous membranes
JVD
Poor capillary refill
Sodium (Na+) is the major cation in which body fluid compartment?
Intracellular fluid (ICF)
Extracellular fluid (ECF)
Both ICF and ECF equally
Plasma only
A patient with hyponatremia might exhibit which physical assessment finding?
Thirst
Muscle irritability
Confusion
Elevated BP
According to the sources, which condition can cause potassium (K+) to shift into the cell, leading to hypokalemia?
Acidosis
Insufficient insulin
Crushing injuries
Insulin administration
Potassium (K+) is the major cation in which body fluid compartment?
Extracellular fluid (ECF)
Intracellular fluid (ICF)
Both ECF and ICF equally
Interstitial fluid only
According to the sources, which electrolyte imbalance is often seen co-occurring with acidosis?
Hyponatremia
Hypernatremia
Hypokalemia
Hyperkalemia
