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WorksheetsDr. Mo Exam 1: Part 1
Total questions: 67
Worksheet time: 38mins
Mr. Zur is taking Spectracef for the treatment of his acute bacterial exacerbation of chronic bronchitis; Which of the following is he ingesting?
Cefmenoxime
Cefpodoxime
Cefditoren
Cefdinir
Cefsulodin
Hyperkalemia may result from the concurrent ingestion of Penicillin VK and all of the following EXCEPT:
Tekturna
Inspra
Invokana
Zestril
Oretic
Which of the following bacteria is BEST classified as a gram-negative, aerobic, non-enteric bacillus?
Neisseria meningitidis
Morganella morganii
Klebsiella pneumoniae
Burkholderia cepacia
Bacteroides fragilis
Which of the following statements is INCORRECT? Concurrent administration of:
Nafcillin and Coumadin may result in a decrease in International Normalized Ratio
Ticarcillin and Lasix may result in additive hypokalemia
Penicillin G and Benemid may result in a decrease in the renal tubular secretion of Penicillin G
Ampicillin and Beyaz may result in contraceptive failure
Penicillin G and an Aminoglycoside, in vivo, may result in the inactivation of the Aminoglycoside
Which of the following is a Major Penicillin Determinant that is employed in the skin test to determine allergy to Penicillin?
Carboxypenicillin
Benzylpenicilloyl-N-propylamine
Benzylpenicilloate
Penicilloyl polylyine
Procaine Penicillin G
An individual who is severely allergic to Tazobactam only should not be given which of the following? SATA
Timentin
Augmentin
Unasyn
Zosyn
Zerbaxa
Which of the following is LEAST LIKELY to result from therapy with Ceftriaxone?
Biliary stasis
Elevation of conjugated bilirubin plasma levels
Kernicterus
Pseudolithiasis
Biliary sludging
Which of the following is MOST LIKELY to be observed during therapy with Rocephin (Ceftriaxone)? SATA
Kernicterus
Biliary Stasis
Biliary Slogging
Elevation of unconjugated bilirubin in the plasma
Pseudolithiasis
Which of the following is the appropriate dosage of Fetroja (Cefiderocol)?
200 mg PO Q8 hrs
500 mg IV infusion Q3 hrs
1 g IV infusion Q 12 hrs
2 g IV infusion over 30 min Q6 hrs
2 g IV infusion over 3 hrs Q8 hrs
Which of the following will grow on a MacConkey agar? (Gram-Negative Organism)
Staphylococcus saprophytic
Streptobacillus Moniliformis
Clostridium difficile
Bacillus anthracis
Peptostreptococcus anaerobium
Which of the following is BEST classified as a 4th-generation Cephalosporin? SATA
Ceftaroline
Cefpirome
Cefozopram
Cefixime
Cefmenoxime
A biological specimen from an infectious disease patient revealed the presence of bacteria like a molar tooth. Which of the following was responsible for the patient's infection?
Burkholderia pseudomallei
Yersinia pestis
Actinomyces Israelii
Staphylococcus aureus
Streptococcus pneumoniae
Which of the following statements about Televancin is FALSE?
It produces a concentration-dependent bactericidal effect
It is effective in the treatment of Vancomycin-resistant Enterococcus-induced endocarditis
It is administered intravenously on a QD basis
It can produce hemorrhagic episodes
It can cause the redman syndrome
Which of the following is LEAST LIEKLY to be observed as an adverse effect of Daptomycin?
Bleeding
Eosinophillic Pneumonia
Myopathy
Hyperkalemia
Hypophosphatemia
Which of the following is LEAST LIKELY to produce the Disulfiram-like effect when administered concomitantly with Alcohol?
Cephalexin
Cefotetan
Cefoperazone
Cefmetazole
Moxalactam
Which of the following is LEAST LIKELY to be nephrotoxic?
Cefazolin (Ancef)
Cefoxitin (Mefoxin)
Cefepime (Maxipime)
Cephalexin (Keflex)
Ceftriaxone (Rocephin)
Which of the following statements about Teflaro is INCORRECT?
It has a half-life of 2.6 hours
It is administered intravenously
About 88% of the administered dose is excreted through the urine
It is rapidly converted to its active moiety by cytochrome P4503A4
It is about 20% plasma protein-bound
Which of the following statements about Teflaro is CORRECT? SATA
About 80% of the administered dose will be excreted through the urine
The drug is about 20% Plasma Protein Bound
It is rapidly converted to its active motility by Phosphatases
It can be given intravenously
It has a half-life of about 2.6 hours
Which of the following inhibits the cross-linking of peptidoglycan after binding to Penicillin-binding protein 2a?
Aztreonam
Imipenem
Ceftobiprole
Bacitracin
Cefixime
Which of the following statements about Azactam is FALSE?
Its half-life is shorter in elderly patients
It binds to PBP-3
It is administered IV and IM
It is excreted through the feces and the urine
It can be given by inhalation
Which of the following statements about Aztreonam (Azactam) is TRUE? SATA
It binds to PBP-3
It can be administered IM and IV
It undergoes excretion through the renal system and through the feces
It's half-life is longer in elderly patients
It can be administered by inhalation
Claforan is LEAST LIKELY to be effective in the treatment of an infection caused by which of the following?
Bacteroides fragilis
Pasteurella maltocida
Shigella Flexneri
Borrelia burgoferi
Haemophilus influenzae
Which of the following is NOT a parameter or factor that is common to Penicillins?
Binding to PBP-1 and PBP-3
Cross-allergenicty
Time-dependent bactericidal effect
6-beta-Aminopenicillinaic acid nucleus
Inhibition of bacterial cell wall synthesis at the third stage
Which of the following is the usual dosage of Pivmecillinam when it is employed in the treatment of uncomplicated UTI?
200 mg PO QID
200 mg IV stat, then 400 mg IV TID
400 mg IV stat, then 200 mg PO Q8 hrs
80 mg PO stat, then 400 mg IV Q8 hrs
400 mg PO Q8 hrs
Which of the following statements about Pivya is FALSE?
It is highly effective against ESBL-producing bacteria
It is highly plasma protein-bound
It has a half-life of 1-1.5 hours
It is a pivalloyloxymethyl ester of Amdinocillin
It is excreted through the urine and bile
Which of the following statements about Teichoplanin is FALSE?
It is shorter-acting than Vancomycin
It has a higher plasma protein-binding capability than Vancomycin
Like Vancomycin, it undergoes urinary excretion
Like Vancomycin, it is effective against Clostridium difficile
Unlike Vancomycin. it does not produce the redman syndrome
Which of the following is LEAST LIKELY to be observed as an adverse effect of Seromycin (Cycloserine)?
Peripheral neuropathy
Fever
Hypermagnesemia
Elevation of blood pressure
Fatigue
Which of the following is a manifestation of Cycloserine-induced neurotoxicity? SATA
Restlessness
Anxiety
Seizures
Irritability
Twitches
Which of the following statements about the mechanism(s) of action of Teixobactin is TRUE? SATA
It binds Lipid II
It binds Lipid III
It prevents the binding of NAG to NAM
It prevents the transportation of Peptidoglycans to the outer surface of the bacterial cell membrane
It inhibits the dephospho rylation of Bactoprenol
Which of the following is LIKELY to produce a toxic type of food poisoning? SATA
Staphylococcus aureus
Salmonella enteritidis
Clostridium botulinum
Campylobacter jejuni
Shigella sonnei
Thioglycolate broth plus Neutral Red is used to identify which of the following bacteria?
Urea-splitting
Indole-positive
Coagulase-positive
Lactose fermenters
Catalase-negative
Which of the following is NOT matched with its correct causative agent?
Scarlet Fever ---> Streptococcus pyogenes
Toxic Shock Syndrome --> Staphylococcus aureus
Lockjaw --> Actinomyces Israelii
Acute Necrotizing Fasciitis --> Group A beta-hemolytic Streptococcus
Plague --> Yersinia pestis
Which of the following is LEAST LIKELY to be a clinical indication of Recarbrio (Imipenem/Cilastatin/Relebactam)?
Complicated Intra-abdominal infection
Complicated UTI
Healthcare-associated bacterial pneumonia
Ventillator-associated bacterial pneumonia
Chronic otitis media
Which of the following is effective against Carbapenem-resistant Enterococcus (CRE)? SATA
Polymyxin B
Teixobactin
Tigecycline
Temocillin
Tebipenem
Which of the following is LEAST LIKELY to be observed as an adverse effect of Cefiderocol?
Atrial fibrillation
Status epilepticus
Hypermagnesemia
Asterixis
Hypersensitivity reaction
Which of the following would be an adverse effect of Fetroja (Cefiderocol)?
Hypersensitivity
Asterixis
Status Epilepticus
Atrial Fibrillation
Hypomagnesemia
Which of the following is a mechanism of action of Fosfomycin? SATA
Inhibition of the translation of RANTES
Inhibition of Interleukins-1 beta, 2 and 8
Increasing the phagocytic activity of neutrophils
Inhibition of pyruval transferase
Prevention of the incidence of Cystic Fibrosis
Which of the following is the usual dosage of Monaural in the management of complicated UTI?
3 gm of granules mixed with 3-4 oz of cold water and taken orally once
500 mg PO BID
1 gm PO BID
4 g IV Q6Hr
8 g IM Q12Hr
Cefazolin is employed prophylactically for which of the following procedures? SATA
Coronary artery bypass grafting
Hysterectomy
Joint Replacement
Dental Surgery
Colorectal Surgery
Which of the following is a common characteristic or property of Vancomycin-related glycopeptides? SATA
Concentration-dependent bactericidal effect
Hemorrhage (Bleeding) Episodes
Long duration of action
IV administration
Effectiveness against VRE
A medical team should exercise caution when administering ____ concurrently with alcohol. SATA
Keflex (Cephalexin)
Cefotan (Cefotetan)
Moxam
Cefobid (Cefoperazone Sodium)
Cefmetazole (Zefazone)
Considering its spectrum of antibacterial activity, Cefotaxin should NOT be used to treat an infection caused by which ion the following?
Borrelia Burgdoferi
Haemophilus Inflenzae (H. Flu)
Shigella F
Bacterodes Fragilis
Asterella Mon
Which of the following is a causative agent of Acute Necrotizing Fasciitis?
Alpha Streptococcus
Group D Beta-hemolytic Streptococcus
Group A Beta-hemolytic Streptococcus
Staphylococcus Dermatitis
Which of the following is LEAST LIKELY to be an adverse effect of Primaxin (Imipenem/Cilastatin)?
Seizures
Headache
Insomnia
Somnolence
Constipation
A Pharmacist should question a prescription that calls for the per os administration of which of the following?
Cefditoren (Spectracef) --> 3rd Gen
Cephalexin (Keflex) --> 1st Gen
Cefuroxime Axetil --> 2nd Gen
Cefoperazone (Cefobid) --> 3rd Gen
Cefpodoxime (Vantin) --> 3rd Gen
Which of the following is LEAST LIKELY to grow on a MacConkey agar?
Bacillus anthraces
Serratia marcescens
Escherichia Coli
Streptobacillus Moniliformis
Providencia Stuartii
Which of the following is involved in the pharmacological action of Primaxin? (SATA) Inhibition of:
Transpeptidase
Carbapenemase
Penicillinase
Dehydropeptidase
Peptidoglycan crosslinking
Which of the following is LEAST LIKELY to be an adverse effect of Daptomycin (Cubicin)?
Coagulation
Nausea and Vomiting
Hypokalemia
Hyperkalemia
Eosiniophilic Pneumonia
Which of the following is an Isoxazollyl Penicillin that can be administered parenterally?
Oxacillin (Bactocill)
Nafcillin (Unipen)
Dicloxacillin (Dynapen)
Methicillin (Staphcillin)
Cloxacillin (Tegopen)
All of the following are common to the glycopeptide antibacterials that are Vancomycin (Vancocin) derivatives EXCEPT:
IV administration
Concentration-dependent bacterial activity
Long-acting
Effectiveness against VRE
Production of the red man syndrome
Select the INCORRECT statement:
Teicoplanin has a higher plasma protein-binding capability than Vancomycin
Vancomycin is administered IV and PO while Teicoplanin is administered IV, IM, and PO
Vancomycin has a longer half-life than Teicoplanin
Vancomycin is more likely than Teicoplanin to cause the red man syndrome
Both Vancomycin and Teicoplanin undergo glomerular filtration
Which of the following is LEAST LIKELY to produce hemorrhagic episodes as an adverse effect?
Ceftriaxone (Rocephin)
Cefazolin (Ancef)
Moxalactam (Latamoxef)
Cefotetan (Cofotan)
Cefoperazone
Considering the antibacterial spectrum of its contents, which of the following is LEAST LIKELY to be an indication of Recarbrio?
Complicated UTI
Complicated Intra-Abdominal Infections
Healthcare-associated bacterial pneumonia
Ventilator-associated bacterial pneumonia
Anthrax
Mr. Qua's endocarditis was caused by a HACEK organism; Which of the following is LEAST LIKELY to be implicated in Mr. Qua's Endocarditis?
Haemophilus aphrophilus
Acinetobacter baumannii
Cardiobacterium hominis
Eiknella corrodens
Kingella Kingae
Which of the following has been implicated in human-bite wounds? SATA
Streptococcus anginosus
Streptococcus pyogenes
Eiknella corrodens
Corynebacterium diphtheriae
Bacteroides fragilis
Which of the following may result from therapy with Ceftriaxone (Rocephin) SATA
Nausea, Vomiting, Diarrhea, and Flatulence
Cholestasis
Kernicterus
Casts in the urine
Pseudolithiasis
Which of the following is LEAST LIKELY to produce a Disulfiram-like action?
Cefamandole (Mandol)
Cephalexin (Keflex)
Cefmetazole (Zefazone)
Cefoperazone
Cefotetan (Cefotan)
Which of the following statements about Fosfomycin is FALSE?
It is used to treat cystitis caused by Vancomycin-resistant Enterococcus faecalis
It is an inhibitor of the 2nd stage of bacterial cell wall synthesis
It is used to treat uncomplicated UTI caused by Escherichia coli
It is effective against Carbapenem-resistant Enterococcus faecalis
It can inhibit RSV-induced inflammation in the lungs
Which of the following inhibits bacterial cell wall synthesis by binding to Lipid II and Lipid III?
Bacitracin
Carbenicillin
Bactoprenol
Teixobactin
Oritavancin
Which of the following is LEAST LIKELY to be an adverse effect of Fetroja?
Hyperkalemia
Atrial Fibrillation
Seizures
Elevation of AST and ALT
Nausea and Vomiting
Which of the following produces its antibacterial effect by first using its siderophore properties to traverse the outer cell membrane of the susceptible bacterium?
Cefdinir
Cefpirome
Cefsulodin
Cefozopram
Cefiderocol
Which of the following is BEST classified as a 5th generation Cephalosporin?
Cefpirome
Ceftobiprole
Cefmenoxime
Cefpodoxime
Ceftibuten
Which of the following is an inhibitor of Pyruval Transferase?
Seromycin (Cycloserine)
Fosfomycin (Monural)
Daptomycin (Cubicin)
Cephamycins
Vancomycin (Vancocin)
Which of the following is an indication of Ampicillin? SATA
Typhus
Nocardiosis
Shingellosis
Gonorrhea
Proteus mirabilis-induced UTI
Amoxicillin is less effective than Ampicillin in the treatment of infections caused by all of the following species EXCEPT:
Actinomyces
Listeria
Shigella
Campylobacter
Escherichia
Additive hyperkalemia may result from the concurrent administration of Penicillin VK and all of the following EXCEPT:
Ramipril (Altace)
Yaz (Ethinyl Estradiol/Drospirenone)
Lasix (Furosemide)
Invokana (Canagliflozin)
Dyrenium (Triamterene)
Which of the following is a Major Penicillin Determinant that is employed in the determination of Penicillin allergy?
Benzylpenicillin
Carboxypenicillin
Penicilloyl-polylysine
Benzylpenicilloy-propylamine
Benzylpenicillolate
