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WorksheetsNeuroscience PRITE Review
Total questions: 50
Worksheet time: 25mins
60 yo right‑handed man, getting lost and writing only on the right half of paper. Left‑sided hemi‑neglect—where is the lesion?
Left parietal lobe
Right frontal lobe
Right parietal lobe
Left occipital lobe
66 yo with long‑standing hypertension develops vertigo, diplopia, nausea, vomiting, hiccups, left‑sided facial numbness, nystagmus, hoarseness, limb ataxia, staggering gait, and a tendency to fall to the left—diagnosis?
Medial medullary stroke
Lateral medullary stroke
Cerebellar hemorrhage
Pontine infarction
26 yo with headaches and right‑hand clumsiness for weeks; exam shows dysdiadochokinesia, intention tremor, and mild dysmetria with an otherwise normal neurologic exam—where would MRI show damage?
Basal ganglia
Cerebellum
Primary motor cortex
Internal capsule
78 yo post‑ischemic‑stroke patient with mild hemiplegia is unaware of weakness, neglects one side when dressing/grooming, and misattributes limb movements—brain area affected?
Right parietal lobe
Left frontal lobe
Right temporal lobe
Left parietal lobe
Adult neurogenesis occurs predominantly in which brain area?
Caudate nucleus
Dentate gyrus of hippocampus
Prefrontal cortex
Amygdala
Left anterior cerebral‑artery infarct most likely produces what clinical picture?
Right facial droop with aphasia
Weakness of contralateral foot and leg sparing face and arm with abulia
Complete homonymous hemianopia
Ipsilateral Horner syndrome
Rapid change to profane, irresponsible behavior over six months suggests pathology in which lobe?
Temporal lobe
Parietal lobe
Frontal lobe
Occipital lobe
Rapid onset of right facial weakness, left‑sided limb weakness, and diplopia indicates what process?
Multiple sclerosis relapse
Brain‑stem infarction
Subdural hematoma
Myasthenic crisis
Orexin (hypocretin) is synthesized in which part of the brain?
Ventromedial hypothalamus
Lateral hypothalamic nuclei
Nucleus basalis of Meynert
Dorsal raphe nucleus
Which brain area is activated by subliminal presentation of emotional faces?
Primary visual cortex
Amygdala
Caudate head
Dorsolateral prefrontal cortex
Histamine is synthesized in which brain region?
Hypothalamus
Pons
Basal forebrain
Cerebellum
The dopaminergic pathway that includes the nucleus accumbens and mediates reinforcement/addiction is the ______ pathway.
Nigrostriatal
Mesolimbic
Tuberoinfundibular
Mesocortical
Leptin acts primarily at which brain region?
Cerebellar vermis
Hippocampus
Hypothalamus
Superior colliculus
Oxytocin suppresses activity in which brain structure?
Amygdala
Putamen
Thalamus
Superior temporal gyrus
Hypothalamic area most closely linked to maternal behavior?
Preoptic area
Supraoptic nucleus
Paraventricular nucleus
Suprachiasmatic nucleus
Cranial nerve responsible for gag reflex and palatal elevation?
Glossopharyngeal nerve (CN IX)
Vagus nerve (CN X)
Facial nerve (CN VII)
Hypoglossal nerve (CN XII)
In the first two years of life, which cortex develops before the other: motor or sensory?
Sensory cortex
Motor cortex
Insular cortex
Cingulate cortex
A key cortical component of the salience network is the ______.
Posterior cingulate cortex
Anterior cingulate cortex
Parahippocampal gyrus
Precuneus
Primary taste cortex in humans lies in which cortical area?
Postcentral gyrus
Anterior insula
Orbitofrontal cortex
Superior temporal gyrus
Initial learning of a skilled motor sequence requires the corticostriatal system and which other system?
Vestibulocerebellar
Corticocerebellar
Corticolimbic
Corticoamygdalar
Reduced hippocampal volume produces impairment of which memory domain?
Procedural memory
Declarative memory
Working memory
Priming
Histaminergic neurons that regulate sleep originate in which nuclei?
Suprachiasmatic nuclei
Tuberomammillary nuclei
Locus coeruleus
Raphe nuclei
Sudden dysarthria, gait ataxia, right‑body numbness, and neck pain after neck manipulation—most likely diagnosis?
Cerebellar hemorrhage
Vertebral artery dissection
Multiple sclerosis
Peripheral vestibulopathy
The stria terminalis connects the amygdala with which areas?
Dorsal raphe nucleus and pons
Septal area and hypothalamus
Ventral tegmental area and thalamus
Hippocampus and cerebellum
Wakefulness depends on what brain system?
Ascending reticular activating system
Periaqueductal gray
Lateral geniculate nucleus
Mammillary bodies
The neural tube forms from which embryonic germ layer?
Endoderm
Mesoderm
Ectoderm
Neural crest
High‑frequency rTMS for major depression targets which cortical region?
Ventromedial prefrontal cortex
Dorsolateral prefrontal cortex
Primary motor cortex
Inferior parietal lobule
Adult neurogenesis is restricted primarily to what region?
Olfactory bulb
Subventricular zone of lateral ventricle
Dentate gyrus of hippocampus
Caudate tail
Of the listed structures, which is part of the hippocampal formation?
Amygdala
Dentate gyrus
Caudate head
Thalamus
Bipolar disorder is associated with decreased connectivity between which regions?
Amygdala and prefrontal cortex
Thalamus and cerebellum
Basal ganglia and parietal cortex
Somatosensory cortex and insula
CNS fear responses are mediated chiefly by what structure?
Central nucleus of the amygdala
Bed nucleus of stria terminalis
Hippocampal CA3
Orbitofrontal cortex
Fear‑related projections to brain‑stem and hypothalamus arise from which amygdalar nuclei?
Basolateral nuclei of the amygdala
Corticomedial nuclei of the amygdala
Centromedial nuclei of the amygdala
Paralaminar nuclei of the amygdala
Remembering a phone number briefly before dialing relies on which brain area?
Posterior parietal cortex
Dorsolateral prefrontal cortex
Entorhinal cortex
Superior temporal gyrus
The circuit enabling resistance to hostile impulses centers on which frontal region?
Orbitofrontal cortex
Supplementary motor cortex
Dorsomedial prefrontal cortex
Inferior parietal lobule
The loop producing worry/obsessive symptoms includes DLPFC, striatum, and which other structure?
Cerebellar dentate nucleus
Thalamus
Amygdala
Hippocampus
Hyperactivity of orbitofrontal cortex, basal ganglia, and thalamus characterizes which disorder?
Panic disorder
Obsessive‑compulsive disorder
Schizophrenia
PTSD
Dopamine neurons mediating cognitive processing belong to which pathway?
Mesolimbic
Mesocortical
Nigrostriatal
Tuberoinfundibular
Stem cells in the adult hippocampus reside in which zone?
Subgranular zone
Hilus
Molecular layer
Alveus
Stroke causing predominant right‑leg weakness, passivity, and abulia likely involves which artery?
Right middle cerebral artery
Left anterior cerebral artery
Right posterior cerebral artery
Left vertebral artery
Hemisensory loss followed by pain/hyperpathia to midline suggests ischemia of which artery?
Middle cerebral artery
Posterior cerebral artery
Anterior choroidal artery
Anterior cerebral artery
Combined third‑nerve palsy and equal face/arm/leg weakness on the right indicates occlusion of a branch of which artery?
Anterior cerebral artery
Posterior cerebral artery
Superior cerebellar artery
Basilar artery
Bilateral leg weakness, abulia/mutism, and incontinence result from occlusion of which artery?
Middle cerebral artery
Basilar artery
Anterior cerebral artery
Anterior choroidal artery
Pure sensory lacunar stroke extending to midline (face, arm, trunk, leg) localizes to what site?
Posterior limb internal capsule
Lateral thalamus
Parietal cortex
Midbrain tegmentum
Right PCA occlusion causes what visual field defect?
Right homonymous hemianopsia
Left homonymous hemianopsia
Bitemporal hemianopsia
Superior quadrantanopia
Bilateral leg/foot anesthetic‑motor deficits with bladder dysfunction in a cocaine user indicate what spinal event?
Posterior spinal artery infarction
Anterior spinal artery infarction
Transverse myelitis
Central cord syndrome
Intact primary somatosensation but inability to recognize objects by touch (astereognosis) suggests lesion where?
Primary somatosensory cortex
Posterior parietal lobe
Dorsolateral prefrontal cortex
Inferior temporal gyrus
Apraxia (loss of learned motor acts) without weakness or ataxia localizes to which cortex?
Left parietal cortex
Right frontal cortex
Left occipital cortex
Cerebellar hemispheres
Romberg negative with eyes open but falls when eyes closed—abnormality in which cerebellar region?
Cerebellar hemispheres
Cerebellar vermis
Vestibular nuclei
Dentate nucleus
Right‑temporal hyperactivity on motor‑speech fMRI indicates damage where?
Calcarine fissure
Broca area
Right insula
Cerebellar vermis
Non‑fluent, effortful “telegraphic” speech (Broca aphasia) localizes to which lobe?
Posterior frontal lobe
Anterior temporal lobe
Inferior parietal lobe
Occipital lobe
