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Penile Carcinoma Quiz

Total questions: 30

Worksheet time: 15mins

Name
Class
Date
1.

The most common histologic type of penile cancer is:

a)

Adenocarcinoma

b)

Basal cell carcinoma

c)

Melanoma

d)

Squamous cell carcinoma

2.

Carcinoma of the penis is most frequently located on the:

a)

Shaft

b)

Glans

c)

Corona

d)

Penile urethra

3.

Which HPV type is most strongly associated with penile carcinoma?

a)

HPV 6

b)

HPV 11

c)

HPV 16

d)

HPV 31

4.

The premalignant lesion most likely to progress to invasive squamous cell carcinoma of the penis is:

a)

Bowenoid papulosis

b)

Condyloma acuminatum

c)

Erythroplasia of Queyrat

d)

Zoon balanitis

5.

Verrucous carcinoma of the penis is:

a)

Highly metastatic

b)

Low-grade with rare metastasis

c)

Always associated with HPV 16

d)

Treated only with chemotherapy

6.

Which of the following is the most important prognostic factor in carcinoma of the penis?

a)

Tumor size

b)

Patient age

c)

Histologic subtype

d)

Nodal status

7.

Which of the following is the most appropriate treatment for carcinoma in situ of the glans penis?

a)

Partial penectomy

b)

Topical 5-fluorouracil

c)

Inguinal lymphadenectomy

d)

Brachytherapy

8.

The initial lymphatic drainage from the penis is to the:

a)

External iliac nodes

b)

Internal iliac nodes

c)

Superficial inguinal nodes

d)

Para-aortic nodes

9.

The recommended surgical margin for partial penectomy in penile carcinoma is:

a)

0.5 cm

b)

1 cm

c)

2 cm

d)

3 cm

10.

The most common site of distant metastasis from penile carcinoma is:

a)

Lung

b)

Liver

c)

Bone

d)

Brain

11.

In penile carcinoma, basaloid histologic subtype is:

a)

Low-grade with excellent prognosis

b)

Associated with HPV and poor prognosis

c)

HPV-negative with good prognosis

d)

Unrelated to prognosis

12.

Bowen's disease is:

a)

CIS of the penile shaft skin

b)

CIS of the glans penis

c)

Invasive SCC of the penis

d)

Verrucous carcinoma

13.

Which of the following penile carcinoma variants is least likely to metastasize?

a)

Sarcomatoid

b)

Basaloid

c)

Warty-basaloid

d)

Verrucous

14.

Inguinal lymphadenectomy is indicated in:

a)

All patients with penile carcinoma

b)

Patients with palpable inguinal nodes after antibiotic trial

c)

Patients with Tis tumors

d)

HPV-positive tumors only

15.

The standard management for T2 penile carcinoma of the glans is:

a)

Topical therapy

b)

Laser excision

c)

Partial penectomy

d)

Total penectomy

16.

Which imaging modality is most useful for local staging of penile carcinoma?

a)

CT pelvis

b)

MRI penis

c)

Ultrasound

d)

PET-CT

17.

The main advantage of sentinel lymph node biopsy in penile carcinoma is:

a)

Avoids need for penectomy

b)

Accurate nodal staging with less morbidity

c)

Improves tumor differentiation

d)

Prevents local recurrence

18.

The histologic feature associated with the poorest prognosis in penile carcinoma is:

a)

Keratin pearls

b)

Papillary pattern

c)

Sarcomatoid differentiation

d)

Verrucous pattern

19.

The most common presentation of penile carcinoma is:

a)

Painless ulcer or mass on the glans

b)

Painful swelling of the shaft

c)

Dysuria

d)

Hematuria

20.

Which factor is most closely linked to reduced incidence of penile carcinoma?

a)

Condom use

b)

Adult circumcision

c)

Neonatal circumcision

d)

HPV vaccination in adulthood

21.

In carcinoma of the penis, the glans is involved in approximately:

a)

10% of cases

b)

30% of cases

c)

50% of cases

d)

80% of cases

22.

The risk of inguinal node metastasis in T1G1 penile carcinoma is approximately:

a)

<5%

b)

10-15%

c)

30-40%

d)

60%

23.

Which topical agent is approved for the treatment of penile carcinoma in situ?

a)

Imiquimod

b)

Cisplatin cream

c)

Tamoxifen

d)

5% salicylic acid

24.

Which of the following is NOT a premalignant lesion of the penis?

a)

Bowen disease

b)

Erythroplasia of Queyrat

c)

Bowenoid papulosis

d)

Lichen planus

25.

The TNM T3 stage of penile carcinoma refers to:

a)

Invasion of corpus spongiosum

b)

Invasion of corpus cavernosum

c)

Invasion of urethral mucosa only

d)

Invasion of tunica vaginalis

26.

Which of the following is the first site of metastatic spread from penile carcinoma?

a)

Pelvic lymph nodes

b)

Superficial inguinal lymph nodes

c)

Deep inguinal lymph nodes

d)

External iliac nodes

27.

Which of the following is true regarding verrucous carcinoma of the penis?

a)

Highly metastatic

b)

Poor prognosis

c)

Often misdiagnosed as condyloma

d)

Associated with high mortality

28.

The most common cause of death in penile carcinoma is:

a)

Local tumor progression

b)

Sepsis from urinary infection

c)

Metastatic disease to lung/liver

d)

Renal failure

29.

Which histologic type is most commonly associated with HPV infection?

a)

Basaloid

b)

Verrucous

c)

Sarcomatoid

d)

Papillary

30.

Which of the following is a common complication after inguinal lymphadenectomy?

a)

Erectile dysfunction

b)

Lymphedema of the lower limb

c)

Urinary incontinence

d)

Hydrocele