Worksheetsseminar quiz
Total questions: 7
Worksheet time: 13mins
Which of the following databases helps explore drug - target interactions?
string database
cytoscape
KEGG pathway
Shiny GO
"NETWORK PHARMACOLOGY CAN HELP IN DRUG REPURPOSING."
(FACT / FICTION ?! )
FACT
( TRUE )
FICTION
( FALSE )
" You discover a plant compound that affects 3 different proteins, What would you do? "
(multiple correct answers ! )
Discard it !
( too many proteins )
Explore furthur possible
interactions
Test only the strongest interaction
study it further
(posible multi - target therapy )
you're developing a drug for diabetes. whats your approach?
Target just one receptor
look at all protein - protein interactions
focus on symptoms
All of the above
Experimental validation comes before computational analysis in network pharmacology.
( true / false )
A research team is studying a bioactive compound from Curcuma longa ( turmeric ) for potential use in treating Alzheimer's disease. Using the TCMSP and STITCH databases, they identify 12 protein targets linked to neuroinflammation and oxidative stress.
A protein- protein interaction networkis constructed in Cytoscape, revealing that TNF, IL-6 , AKT1 are key hub proteins. The researchers then perform pathway enrichment analysis, which highlights the PI3K - Akt and NF-kB pathways. Laboratory validation confirms the compound's ability to reduce inflammatory markers in cell models.
Which of the following databases were used in this study to identify targets ?
PubMed & STRING
TCMSP & STITCH
KEGG & CHEMBL
None of the above
which proteins acted as hubs in the network?
The pathways researchers obtained after pathway enrichment analysis, are (a)
In one word, how do you feel about today's session ?
