WorksheetsChapter 61 Pharm Final Review
Total questions: 73
Worksheet time: 37mins
What is acne?
A chronic disease characterized by erythema and telangiectasis
A disorder of the hair follicles and sebaceous glands that become clogged
A common type of ringworm infection
Widespread sloughing of the skin with severe mucositis
Which condition is also known as athlete’s foot?
Rosacea
Urticaria
Tinea pedis
Psoriasis
What is the primary purpose of corticosteroid drug therapy?
To treat bacterial infections
To reduce inflammation in dermatologic conditions
To increase skin pigmentation
To promote hair growth
Which of the following is characterized by redness of the skin?
Pruritus
Erythema
Dermatitis
Acne vulgaris
What is urticaria commonly known as?
Eczema
Hives
Athlete’s foot
Rosacea
What is the recommended starting approach for potency and duration when using topical corticosteroids?
Start with highest potency and longest duration
Start with lowest potency and shortest duration
Start with medium potency and moderate duration
Start with highest potency and shortest duration
Which of the following is a pharmacologic action of topical corticosteroids?
Increase inflammation
Suppress release of kinins, histamine, prostaglandins
Decrease skin absorption
Enhance immune response
What is a common adverse effect of high potency topical corticosteroids?
Increased risk of infections
Risk of Cushing syndrome and HPA axis suppression
Enhanced skin healing
Increased energy levels
Which organisms are commonly associated with antibacterial drug therapy?
Escherichia coli
Streptococci and Staphylococci
Mycobacterium tuberculosis
Candida albicans
What type of infection is characterized by erythema, tenderness, and edema, and can spread to subcutaneous tissue?
Folliculitis
Impetigo
Cellulitis
Furuncles
Which drug is indicated for gram-negative soft tissue infections?
Cephalosporins
Tetracyclines
Fluoroquinolones
Neomycin
What skin disorder is common in puberty due to hormonal changes?
Rosacea
Impetigo
Acne
Cellulitis
Which topical antibacterial is used to prevent postoperative surgical infection?
Neomycin
Bacitracin
Mupirocin
Polymyxin
What is the function of silver sulfadiazine in burn care?
It acts as a moisturizer
It releases silver for broad-spectrum antimicrobial action
It is used for pain relief
It promotes rapid healing
What is a common treatment for severe skin reactions like Toxic Epidermal Necrolysis (TEN)?
Antiviral medication
Culture-directed antibacterial therapy
Antifungal treatment
Steroid injections
Which of the following is a common drug trigger for Stevens-Johnson Syndrome (SJS)?
Ibuprofen
Allopurinol
Paracetamol
Aspirin
What is the purpose of administering mupirocin intranasally before surgery?
To reduce inflammation
To prevent MRSA infection
To enhance wound healing
To decrease pain
Which of the following is NOT a guideline for general skin health?
Eat a balanced diet
Avoid excess sun exposure
Use occlusive dressings regularly
Maintain good personal hygiene
When does the risk of systemic absorption of topical corticosteroids increase?
When the medication is mild
When the medication is potent
When applied to dry skin
When used infrequently
Which of the following is a tip for preventing skin disorders?
Use harsh cleaners and latex gloves
Bathe in warm water with a mild cleanser
Rub skin dry after washing
Avoid using any lotion or oil
What should be done to avoid scratching lesions?
Use harsh soaps
Keep fingernails long
Wear cotton gloves at night
Rub lesions frequently
What is the correct procedure for applying medication to the skin?
Apply a thick layer of medication
Rub in a small amount well
Wash hands only after application
Apply only to visible lesions
What is a specific instruction for using Azelaic Acid (Azelex)?
Use occlusive dressings
Use for a short period
Do not use occlusive dressings/wraps
Apply only to visible lesions
What is the recommended frequency for using benzoyl peroxide cleansing solutions initially?
1–2 times daily
3–4 times daily
Once a week
Every other day
Which of the following is a common cause of fungal infections of the skin and mucus membranes?
Bacterial infection
Candida albicans
Viral infection
Parasitic infection
What should be done if stinging or burning occurs when using benzoyl peroxide?
Increase the dosage
Apply more frequently
Wash off with mild soap/water and skip until next day
Continue use without changes
What is the treatment for antifungal infections?
Antibiotics
Antiviral agents
Topical or systemic antifungal agents
Antiparasitic agents
What is the primary use of Nystatin in medical treatment?
To treat bacterial infections
To bind to sterols in fungal cell membranes
To enhance viral replication
To inhibit DNA synthesis
Which of the following drugs is used to treat dermatophyte infections?
Acyclovir
Nystatin
Butenafine
Trypsin
What is the role of acyclovir triphosphate in antiviral therapy?
It enhances viral replication
It inhibits DNA synthesis and viral replication
It binds to fungal cell membranes
It promotes ergosterol synthesis
Which enzyme is NOT mentioned as used for wound debridement?
Trypsin
Collagenase
Papain
Amylase
What type of infections does herpes simplex type 1 usually involve?
Genitalia
Face or neck
Feet
Hands
What is the role of collagen in the products mentioned in the document?
It decreases epithelial tissue.
It stimulates angiogenesis and increases epithelial tissue.
It inhibits angiogenesis.
It reduces inflammation.
Which of the following is a topical immunosuppressant drug for severe atopic dermatitis?
Alefacept
Tacrolimus
Etanercept
Infliximab
What is a potential risk associated with systemic immunosuppressant drugs like etanercept?
Skin cancer
Increased infection risk
Hair loss
Weight gain
Which antihistamine is considered more sedating?
Cetirizine
Loratadine
Diphenhydramine
Fexofenadine
What is the purpose of using nitroglycerin for hemorrhoids?
To reduce bleeding
To prevent constipation
To treat thrombosed external hemorrhoids
To increase blood pressure
Which ingredient is used to relieve dry skin and pruritus?
Salicylic acid
Lanolin
Alpha hydroxy acids
Sunscreens
What is the primary function of alpha hydroxy acids in skincare?
Remove warts
Treat wrinkles and sun-damaged skin
Protect from UVA and UVB
Relieve dry skin
What is a common characteristic of acne vulgaris?
It only affects the scalp
It involves blockage and inflammation of hair follicles
It is caused by viral infections
It is unrelated to puberty
Which of the following is NOT a pathologic event in acne-infected hair follicles?
Androgen-mediated stimulation of sebaceous gland activity
Abnormal keratinization causing follicular plugging
Proliferation of P. acnes bacteria
Decreased sebum production
What role do P. acnes bacteria play in acne lesions?
They reduce inflammation
They produce lipase enzymes that break down free fatty acids
They decrease sebum production
They prevent follicular plugging
Which of the following diets is suggested to reduce inflammatory lesions in teenagers?
High glycemic load diets
Low glycemic load diets
Diets high in chocolate
Diets rich in zinc
What is the primary goal of acne treatment according to the document?
Increase P. acnes
Reduce inflammation by eliminating P. acnes
Promote skin dryness
Enhance skin pigmentation
Which topical antimicrobial is noted for its antibacterial activity against P. acnes and is as effective as benzoyl peroxide?
Clindamycin
Erythromycin
Azelaic acid
Tretinoin
What is a common adverse effect of benzoyl peroxide mentioned in the document?
Skin hydration
Irritant dermatitis
Increased pigmentation
Hair growth
Which oral antibiotic is noted for reducing P. acnes-induced inflammatory cytokines?
Clindamycin
Erythromycin
Tetracycline
Azelaic acid
Which of the following antibiotics is known to inhibit bacterial folic acid synthesis?
Tetracycline
Trimethoprim–sulfamethoxazole
Erythromycin
Minocycline
What is the minimum recommended duration for the use of oral antibiotics?
2 to 4 weeks
4 to 6 weeks
6 to 8 weeks
8 to 10 weeks
Which topical retinoid is often used with other products for treating acne?
Adapalene
Tazarotene
Isotretinoin
Acitretin
According to the QSEN study, what percentage of improvement in quality of life was observed in patients receiving isotretinoin treatment by month two?
25%
50%
75%
100%
What is aloe commonly used for in herbal preparations?
To treat bacterial infections
To reduce acne
To decrease pain, itching, and inflammation
To improve digestion
What is the primary benefit of using oats topically?
To reduce itching from histamine production
To treat minor skin irritation and pruritus
To inhibit arachidonic acid metabolism
To increase blood flow to the area
Which of the following is a characteristic of isotretinoin?
It increases sebum production
It inhibits comedone formation
It accelerates cell proliferation
It decreases differentiation in neuroblastoma
What is a known effect of retinoids on skin cells?
They decrease differentiation
They inhibit proliferation
They promote proliferation and differentiation
They increase sebum production
What is the role of isotretinoin in treating acne?
It increases sebum viscosity
It suppresses sebum production
It promotes P. acnes growth
It enhances comedone formation
What is the primary use of Isotretinoin?
Treating mild acne
Treating severe recalcitrant nodular acne
Treating eczema
Treating psoriasis
Why is Isotretinoin contraindicated in pregnancy?
It causes nausea
It causes severe congenital malformations
It causes dry skin
It causes headaches
Which of the following is a BLACK BOX WARNING associated with Isotretinoin?
Dry skin
Severe congenital malformations and spontaneous abortions
Nausea and vomiting
Hyperlipidemia
What should be monitored due to the risk of hepatotoxicity when using Isotretinoin?
Blood pressure
Liver enzymes
Heart rate
Blood sugar levels
Which of the following is a contraindication for Isotretinoin?
Hypersensitivity to isotretinoin
History of migraines
High blood pressure
Seasonal allergies
What should be done before starting isotretinoin treatment?
Perform a skin allergy test
Conduct baseline CBC, fasting lipid profile, and liver function tests
Start a vitamin A supplement
Increase sun exposure
How should isotretinoin capsules be taken to avoid esophageal irritation?
With a small sip of water
On an empty stomach
Swallowed whole with a full glass of liquid
Chewed before swallowing
What is the ideal reduction in total cyst count when assessing the therapeutic effects of isotretinoin?
30%
50%
70%
90%
Which of the following is a sign of hypervitaminosis A to watch for during isotretinoin treatment?
Increased appetite
Blurred vision
Weight gain
Improved skin texture
What should patients avoid during isotretinoin therapy to prevent skin dryness and irritation?
Using regular soap
Using sunscreen
Using abrasive or medicated soaps
Drinking plenty of water
Which of the following substances increases the risk of pseudotumor cerebri?
Alcohol
Tetracycline
Phenytoin
Vitamin A
What is the only topical retinoid available without a prescription?
Tazarotene
Isotretinoin
Adapalene
Benzoyl peroxide
What is required before starting isotretinoin therapy according to the iPLEDGE program?
One negative pregnancy test
Two negative pregnancy tests
A prescription from any doctor
A signed consent form
How often must patients see their healthcare provider while on isotretinoin according to the iPLEDGE program?
Weekly
Bi-weekly
Monthly
Every two months
What is the maximum supply of isotretinoin that can be prescribed at each monthly visit?
15-day supply
30-day supply
45-day supply
60-day supply
What must physicians certify to meet provider requirements for acne treatment?
Expertise in dermatology
Expertise in acne diagnosis and treatment
Expertise in cosmetic surgery
Expertise in general medicine
What must all patients be counseled on, regardless of pregnancy potential?
iPLEDGE and the risks of congenital anomalies
General health and wellness
Diet and exercise
Stress management techniques
