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BSC203_Review_Week1-2

Total questions: 30

Worksheet time: 23mins

Name
Class
Date
1.

This product is classified as a herbal supplement. This health product lack of which following scientific data?

a)

Data from in vitro study.

b)

Data from in vivo study.

c)

Data from a randomized placebo-controlled clinical trial.

d)

Data from a randomized blinded clinical trial.

2.

Pharmacokinetic data of a drug (adsorption, distribution, metabolism, excretion) is studied in which of the following phases of a clinical trial?

a)

Phase 1

b)

Phase 2

c)

Phase 3

d)

Phase 4

3.

Scientific data from which following phase of a clinical trial are the most important to determine the efficacy and safety of a drug to launch that drug to the marketing for human use?

a)

Phase 1

b)

Phase 2

c)

Phase 3

d)

Phase 4

4.

The study design is often employed in the phase 3 of a clinical trial of new investigational drugs?

a)

Randomized double-blinded placebo-controlled clinical trial

b)

Randomized double-blinded standard treatment-controlled clinical trial

c)

Randomized single-blinded placebo-controlled clinical trial

d)

Randomized single-blinded standard treatment-controlled clinical trial

5.

What is the drug's generic name of this pharmaceutical product?

a)

Ventolin

b)

GlaxoSmithKline

c)

Salbutamol

d)

VentolinTM Injection

6.

Which of the following would be the most important for a nurse to do to ensure the safe use of a prescription drugs in the clinical setting? Select all that apply.

a)

Adhere "5-rights" principle when administering drugs.

b)

Monitoring patients for drug's effects and toxicities after administering drugs.

c)

Prescribing drugs following the evidence-based medicine practice.

d)

Educating patients/caregivers about drugs.

7.

The "5-rights" principle of a safe drug administration DOES NOT include which of following element?

a)

Name of the patient

b)

Name of the drug

c)

Dosage of the drug

d)

Route of the drug.

e)

Price of the drug.

8.

Which of following routes of drug administration will give a complete bioavailability?

a)

Oral administration

b)

Intravenous administration

c)

Subcutaneous administration

d)

Inhale administration

9.

Which of the following information is NOT TRUE about over-the-counter drugs?

a)

Referred to non-prescription drugs.

b)

Not require a completion of phase 3 clinical trial to be used in humans.

c)

Not require a licensed healthcare provider's signature.

d)

They are drugs with a broad therapeutic index.

10.

Which of following pharmacokinetic parameters determines the dosage interval of a drug?

a)

Bioavailability

b)

Distribution volume

c)

Half-life

d)

First-pass effect

11.

Which of the following pharmacokinetic phase of a drug is altered significantly in patients with a change in serum albumin levels?

a)

Adsorption

b)

Distribution

c)

Metabolism

d)

Excretion

12.

A cancer patient asks the nurse's advice on using a traditional herbal medicine for her cancer treatment as she heard from a crowd that it worked well in several people. The nurse checked the herbal product and found following information written in the label "efficacy and safety of this herbal medicine were already proven in a clinical study using survey questionnaire on 5000 people". Which of following statements is CORRECT about the efficacy and safety information of this herbal medicine?

a)

There is no scientific data proving efficacy and safety of this herbal medicine because this is not a randomized, controlled clinical trial.

b)

The scientific data on efficacy and safety of this herbal medicine is strong because this clinical study was performed in 5000 people.

c)

The scientific data on efficacy and safety of this herbal medicine is strong because this clinical trial was performed in 5000 people and it worked well in several people already.

d)

There is not sufficient scientific data proving efficacy and safety of this herbal medicine because it requires more data from other clinical studies with the same survey questionnaire.

13.

A nurse is preparing to administer a prescribed medication to a patient. The nurse needs to recognize which of following as possible factor that could alter/modify the drug response? Select all that apply.

a)

Age

b)

Sex

c)

Polypharmacy

d)

Weight

e)

Disease status

14.

A nurse finds an interesting scientific article/paper about patient safety regarding the post-marketing surveillance phase of a cancer drug that has been using in her hospital. Which of following of the paper contents would the nurse expects to find?

a)

Healthcare providers report adverse effects of the drug.

b)

Healthy volunteers are involved in the test.

c)

The drug is given to hundred to thousand patients with cancer.

d)

In vitro tests are performed using human cancer cells.

15.

The nurse observes that after administration of a drug the patient has developed itching and a skin rash. The nurse interprets these findings as which of the following, EXCEPT?

a)

Drug adverse reaction

b)

Drug allergic reaction

c)

Drug adverse event

d)

Drug interaction reaction

16.

A patient is receiving Digoxin as treatment of heart failure. This is one of high-alert medications. Which of the following would be the most important for the nurse to bear in mind when administering this medication to the patient?

a)

The minimum effective concentration and minimum toxic concentration of digoxin are very close.

b)

Digoxin is very easy to be confused with other drugs due to look-alike, sound-alike (LASA) effects.

c)

Drug adverse effects of digoxin are unavoidable because this a high-alert medication.

d)

The ratio of minimum toxic concentration and minimum effective concentration of digoxin are very large.

17.

A nurse is monitoring a patient after intravenously administering a penicillin - an antibacterial drug. Which of the following signs/symptoms would alert the nurse to suspect that the patient is developing anaphylactic shock (most severe drug allergy reaction)? Select all that apply.

a)

Bradycardia (decreased heart rate)

b)

Hypertension (increased blood pressure)

c)

Dyspnea (shortness of breath)

d)

Urticaria (itchy, raised red areas on the skin)

e)

Angioedema (swelling in the tissue under the skin)

18.

From 1999 to 2003, Vioxx (rofecoxib) was considered as "blockbuster = making billions of dollars" drug of the MERCK company which claimed that this drug was effective for pain and safer for the stomach than other traditional NSAIDs. However, it was globally withdrawn in 2004 because long-term data revealed a significantly increased risk of myocardial infarction and stroke. This example of VIOXX case underscores the critical importance of?

a)

Phase 1 for establishing the toxicity and determining maximum tolerated dose in humans.

b)

Phase 2 for establishing efficacy in a small patient population.

c)

Phase 3 for confirming efficacy and safety under controlled conditions.

d)

Phase 4 for identifying rare or long-term adverse effects in the general population.

19.

A nurse has administered drugs to a patient as per the physician's orders. Which of the most following important activities should the nurse perform after administering the prescribed drugs to the patient?

a)

Record symptoms of the condition

b)

Communicate with patient/caregiver to ensure the "5-rights" principle of a safe medication administration

c)

Obtain history of drug allergy

d)

Check for drug adverse reactions

e)

Double-check with another nurse to ensure the "5-rights" principle of a safe medication administration

20.

The nurse administers a drug that is supplied as an enteric-coated tablet. The patient asks the nurse about this form of tablet as it is more expensive than the one that she had used before. Which following response by the nurse would be most accurate?

a)

“The medication dissolves directly from the stomach into your body.”

b)

“The drug breaks up into pieces as it moves through the stomach.”

c)

“The medication bypasses the gastrointestinal (GI) tract and goes quickly into the bloodstream.”

d)

“The drug dissolves into fragments after it reaches your small intestine.”

21.

A nurse is reading a journal article about seasonal allergies and comes across the name of the drug loratadine. The nurse identifies this drug name as which of the following?

a)

Chemical name

b)

Generic name

c)

Brand name

d)

Company name

22.

After teaching a group of nursing students about pharmacokinetics, the instructor determines that the teaching was successful when the students identify which of the following as the site for the metabolism of most drugs

a)

Liver

b)

Lung

c)

Kidney

d)

Intestine

23.

After teaching a group of nursing students about pharmacokinetics, the instructor determines that the teaching was successful when the students identify which of the following as the most important site for the excretion of most drugs?

a)

Liver

b)

Lung

c)

Kidney

d)

Intestine

24.

Which of the following reflects a nurse's responsibility when a drug is prescribed for a patient? Select all that apply

a)

Administering the drug to the patient

b)

Monitoring for therapeutic response

c)

Checking for drug–drug interactions

d)

Reporting drug adverse reactions

e)

Teaching the patient information needed to administer drugs safely at home

25.

A group of nursing students are reviewing the concept known as the "5+-rights" of drug administration. The group demonstrates understanding of this concept when they identify which of the following as being included? Select all that apply.

a)

Right patient

b)

Right drug

c)

Right route

d)

Right dose

e)

Right prescriber

26.

Prior to administering a prescribed drug, the nurse correctly identifies the client by which method? Select all that apply.

a)

Checking a patient's name on his/her wristband

b)

Checking a patient's name chart

c)

Asking the patient to identify himself/herself and give his/her birth date

d)

Asking a patient if he/she is the correct patient

e)

Using a current picture of the patient if available

27.

When completing the check to ensure that the right drug is being administered to the patient, which of the following should the nurse compare, EXCEPT?

a)

Medication/Container label

b)

Nursing notes

c)

Medication record in the physician's order

d)

Medication administration record (MAR)

28.

A nurse is preparing a presentation for a group of nurses about actions that nurses can do to help prevent medication errors. Which of the following would the nurse include? Select all that apply

a)

Rechecking all dosage calculations

b)

Administering the drug before answering any of the patient's questions

c)

Avoiding distractions and concentrating on only one task at a time

d)

Practicing the "5+-rights of drug administration

29.

A patient has an physician's order to receive 10 units of rapid-acting insulin at bedtime via subcutaneous injection. The nurse would expect to do which of the following actions before and after administering this medication?

a)

Check patient's blood glucose levels

b)

Documenting administration of the drug

c)

Informing the patient about the type of drug

d)

Updating the physician regarding the patient's condition

30.

A nurse is preparing to administer an intravenous injection to a patient for the first time. Which of the following would be most important for the nurse to do?

a)

Obtain the patient's allergy history

b)

Obtain information about the drug

c)

Inquire if the patient has any objections to syringes

d)

Discuss the dosage with other nurses