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Unit 4 Study Guide

Total questions: 74

Worksheet time: 37mins

Name
Class
Date
1.

Which action is priority in the first 24 hours after esophageal cancer surgery?

a)

Maintain Fowler’s or semi-Fowler’s positioning

b)

Clamp the chest tube to limit drainage

c)

Encourage oral fluids to promote hydration

d)

Reinsert the nasogastric tube if dislodged

2.

After esophagectomy, the nasogastric drainage is expected to appear how during the first 5–7 days?

a)

Bloody then greenish-yellow later

b)

Clear and odorless throughout

c)

Milky and frothy immediately

d)

Brown and thick from day one

3.

Which finding should be reported immediately in a post-esophagectomy patient with a chest tube?

a)

Minimal fluctuation with quiet respirations

b)

No bubbling in the water seal chamber

c)

Serous drainage totaling 50 mL in 12 hours

d)

Drainage greater than 400–600 mL in 8 hours

4.

For head and neck cancer post-op care with a tracheostomy, which intervention is essential?

a)

Removal of the trach within 24 hours

b)

Covering skin flaps with bulky dressings

c)

Routine manipulation of the nasogastric tube

d)

Frequent trach suctioning and airway management

5.

A patient with a new neck skin flap after surgery requires which nursing approach?

a)

Ambulation only after 72 hours post-op

b)

Hourly checks and avoiding pressure on tissue

c)

Continuous heat packs over the flap site

d)

Firm dressing to reduce edema formation

6.

Which measure helps prevent respiratory complications after stomach cancer surgery?

a)

Splint the incision with coughing and deep breathing

b)

Avoid incentive spirometry during early recovery

c)

Restrict ambulation until pain fully resolves

d)

Limit repositioning to once every 12 hours

7.

Following gastrectomy, what nasogastric tube observation requires provider notification?

a)

Drainage exceeding 75 mL and persistent blood

b)

Thin yellow-green fluid after 48 hours

c)

Small air bubbles with minimal output

d)

Decreased edema and reduced aspirate

8.

Which set of signs is most concerning for an anastomotic leak after stomach surgery?

a)

Transient anxiety relieved by reassurance

b)

Clear serous drainage and stable vital signs

c)

Mild nausea, passing flatus, and hunger return

d)

Tachycardia, dyspnea, fever, and abdominal pain

9.

In pancreatic cancer post-op care, which ongoing need is commonly required?

a)

Strict bedrest without ambulation

b)

Continuous IV insulin infusion

c)

Routine NPO for seven full days

d)

Pancreatic enzyme replacement for digestion

10.

Which urine output threshold after pancreatic surgery should be reported promptly?

a)

About 90 mL per hour

b)

Exactly 50 mL per hour

c)

Greater than 60 mL per hour

d)

Less than 30 mL per hour

11.

For colon cancer surgery with a new colostomy, which early finding is normal?

a)

Stoma pink to red with mild swelling

b)

Stoma pale and dusky with no bleeding

c)

Stoma black with firm crusting tissue

d)

Stoma white to gray without moisture

12.

Which instruction is appropriate for a patient with a new colostomy regarding gas and drainage?

a)

Ignore drainage amount because it is unpredictable

b)

Clamp the pouch to retain gas and reduce odor

c)

Report any gas immediately as a surgical emergency

d)

Expect excess gas for about two weeks temporarily

13.

Which exposure is a major risk factor for head and neck cancers?

a)

Long-term probiotic use

b)

Persistent HPV infection

c)

High-fiber diet intake

d)

Chronic calcium deficiency

14.

Which behavior most increases risk for lung cancer?

a)

Cigarette smoking

b)

Daily multivitamins

c)

High water intake

d)

Regular stretching

15.

Which environmental agent is linked with lung cancer risk?

a)

Radon and asbestos

b)

Silica and sodium

c)

Ozone and helium

d)

Neon and argon

16.

Which is a modifiable risk factor for stomach cancer?

a)

Dietary smoked foods

b)

Advanced patient age

c)

Male biological sex

d)

Blood type O status

17.

Which combination is a recognized risk factor set for pancreatic cancer?

a)

Iron deficiency and anemia

b)

Low-fat diet and exercise

c)

Smoking and chronic pancreatitis

d)

Viral hepatitis A infection

18.

Which virus pair is most associated with liver cancer in the United States?

a)

EBV and VZV

b)

HIV and CMV

c)

HPV and HSV

d)

HBV and HCV

19.

Which patient history most increases colorectal cancer risk?

a)

Tonsillectomy in adolescence

b)

Seasonal allergies history

c)

Appendectomy in childhood

d)

First-degree relative with CRC

20.

Which dietary pattern raises colorectal cancer risk?

a)

Mediterranean low red meat intake

b)

Strict low-sodium DASH pattern

c)

Daily legumes and leafy greens

d)

More than seven red meat servings weekly

21.

A patient starting chemotherapy develops hyperuricemia. Which nursing action is appropriate?

a)

Monitor uric acid levels

b)

Restrict all dietary protein

c)

Apply cold packs to joints

d)

Schedule daily chest X‑rays

22.

During anthracycline therapy, which monitoring best detects cardiotoxicity?

a)

ECG and ejection fraction

b)

Peak expiratory flow

c)

Glucose tolerance test

d)

Serum amylase level

23.

A patient post-radiation presents months later with dyspnea and chest discomfort. Which complication is most likely?

a)

Pericarditis or myocarditis

b)

Clostridioides difficile colitis

c)

Acute pulmonary embolism

d)

Autoimmune thyroiditis

24.

A nurse notes declining ejection fraction during chemotherapy. What is the best immediate action?

a)

Notify provider to adjust drug therapy

b)

Increase patient fluid boluses now

c)

Start empiric broad antibiotics

d)

Switch to high-intensity exercise

25.

Which intervention best supports anorexia during chemotherapy?

a)

Encourage prolonged fasting to stimulate appetite

b)

Restrict intake to two large balanced meals daily

c)

Prioritize low-protein low-calorie bland snacks

d)

Offer small frequent high-protein high-calorie meals

26.

A patient on chemotherapy reports four loose stools daily. What initial diet teaching is most appropriate?

a)

Choose low fiber low residue foods and hydrate

b)

Increase insoluble fiber and raw vegetables intake

c)

Adopt ketogenic high fat very low carb meals

d)

Use dairy-rich smoothies with extra lactose

27.

For stomatitis prevention in chemotherapy, which routine is recommended?

a)

Daily alcohol-based mouthwash gargles

b)

Frequent saline or salt-soda mouth rinses

c)

Sucking lemon candies to stimulate saliva

d)

Toothbrushing once daily with hard bristles

28.

Which statement shows correct teaching for nausea and vomiting after highly emetogenic therapy?

a)

Take prescribed antiemetics on schedule for 2–3 days

b)

Stop fluids for 24 hours to rest the stomach

c)

Avoid antiemetics unless vomiting starts repeatedly

d)

Use PRN antiemetics only at bedtime for sleep

29.

Which lab should be monitored for suspected hepatotoxicity during chemotherapy?

a)

Serum amylase and lipase levels

b)

Urinalysis for protein and glucose

c)

Liver function tests including transaminases

d)

Arterial blood gas with lactate

30.

Which instruction supports constipation prevention in a chemotherapy patient?

a)

Reduce fluids to minimize abdominal cramping

b)

Use stool softeners as needed and increase fiber

c)

Take daily stimulant laxatives regardless

d)

Avoid fiber and limit walking to prevent strain

31.

Key nursing priority in leukopenia management is to:

a)

Delay reporting of low-grade fevers

b)

Encourage gardening and soil exposure

c)

Teach to avoid crowds and sick contacts

d)

Discontinue all growth factors promptly

32.

A patient with thrombocytopenia needs which precaution?

a)

Administer aspirin for mild headaches

b)

Use firm flossing to clean the gums

c)

Encourage intramuscular injections routinely

d)

Observe for bleeding and monitor platelets

33.

Which measure is appropriate for hemorrhagic cystitis risk?

a)

Restrict hydration to avoid bladder distension

b)

Avoid reporting hematuria unless painful

c)

Delay voiding to concentrate cytoprotectants

d)

Increase fluid intake for 24–72 hours post-treatment

34.

To reduce nephrotoxicity during chemotherapy, which action is indicated?

a)

Focus only on electrolytes while continuing NSAIDs

b)

Alkalinize serum pH using oral vinegar intake

c)

Monitor BUN and creatinine and avoid nephrotoxic drugs

d)

Hold allopurinol to prevent uric acid reduction

35.

Which counseling is essential before starting therapy with gonadotoxic risk?

a)

Reassure that fertility will return within months

b)

Discuss fertility risks and options for gamete banking

c)

Delay conversations until after first treatment

d)

Recommend herbal agents to preserve fertility

36.

Best advice to manage alopecia distress during chemotherapy is to:

a)

Explore wigs scarves and hairpieces before hair loss

b)

Shave scalp immediately without discussion

c)

Schedule tight braids to retain hair follicles

d)

Increase daily hot blow-drying for scalp health

37.

Which set describes common chemotherapy-induced skin changes?

a)

Acneiform eruptions acral erythema hyperpigmentation photosensitivity

b)

Hives scabies psoriasis dermatophyte infection

c)

Vitiligo petechiae livedo reticularis frostbite

d)

Necrosis varicose ulcers keloid hypertrophy

38.

For radiation skin reaction with dry to moist desquamation, which step is appropriate?

a)

Cover tightly with plastic wrap all day

b)

Apply strong perfume lotions for fragrance

c)

Scrub vigorously with loofah and hot water

d)

Gently cleanse with mild soap soft cloth pat dry

39.

Which topical product may reduce pruritus in irradiated skin if approved?

a)

Over-the-counter hydrocortisone cream

b)

High-potency fluorinated steroids daily

c)

Antibiotic ointment for routine use

d)

Alcohol rubs to dry the area

40.

What environmental advice protects irradiated skin during healing?

a)

Use tanning beds briefly to thicken skin

b)

Soak daily in hot chlorinated pools

c)

Avoid sun exposure and excessive heat sources

d)

Apply heating pads to improve circulation

41.

Which cognitive support strategy is recommended during chemotherapy-related brain fog?

a)

Use a detailed daily planner and rest adequately

b)

Rely on memory rather than writing plans

c)

Multitask constantly to train working memory

d)

Avoid all exercise to reduce fatigue burden

42.

A patient develops distal paresthesias and weakness from chemotherapy. Initial management may include:

a)

Begin anticoagulation to improve nerve perfusion

b)

Start daily corticosteroids for lifelong therapy

c)

Increase dose to speed tumor response quickly

d)

Temporarily reduce or interrupt dose and consider gabapentin

43.

Which finding during bone marrow suppression typically occurs 7–10 days after starting therapy?

a)

Immediate thrombocytosis within two days

b)

Stable platelets with isolated lymphocytosis

c)

Nadir of WBC platelets and RBC counts

d)

Peak hemoglobin with neutrophil recovery

44.

Which instruction for oral mucositis pain control is appropriate?

a)

Limit rinses to once daily with strong alcohol

b)

Use topical anesthetics and choose moist soft foods

c)

Prefer spicy acidic foods to stimulate saliva

d)

Talk extensively during meals to distract pain

45.

Which TNM designation indicates no evidence of a primary tumor?

a)

T1 indicates no primary tumor evidence

b)

Tx indicates no primary tumor evidence

c)

T0 indicates no primary tumor evidence

d)

Tis indicates no primary tumor evidence

46.

A patient’s regional lymph nodes cannot be clinically assessed. Which N category applies?

a)

N0 indicates no nodal disease detected

b)

N4 indicates extensive nodal involvement

c)

N1 indicates mild nodal involvement present

d)

Nx indicates lymph nodes not assessable

47.

Which statement best describes M1 in the TNM system?

a)

M1 means metastases cannot be determined

b)

M1 means distant metastases are present

c)

M1 means local lymph nodes are positive

d)

M1 means no distant metastases found

48.

Chemotherapy most commonly causes the first nadir in which cell line, and when does it occur?

a)

Platelets with nadir at 24–48 hours

b)

Neutrophils with nadir at 7–10 days

c)

Lymphocytes with nadir at 3–4 months

d)

Erythrocytes with nadir at 2 weeks

49.

At what absolute neutrophil count (ANC) is chemotherapy typically held due to infection risk?

a)

ANC below 1,500 cells per mm3

b)

ANC below 50 cells per mm3

c)

ANC below 500 cells per mm3

d)

ANC below 5,000 cells per mm3

50.

When is platelet transfusion generally considered during chemotherapy-induced thrombocytopenia?

a)

When platelets are under 20,000 per µL

b)

When platelets are under 50,000 per µL

c)

When platelets are under 150,000 per µL

d)

When platelets are under 5,000 per µL

51.

Why does red blood cell recovery after chemotherapy take longer than other lines?

a)

RBCs lack any marrow precursors

b)

RBC lifespan is about 120 days

c)

RBCs are destroyed by neutrophil toxins

d)

RBCs are sequestered in lymph nodes

52.

Which normal hemoglobin range is correct for adult males?

a)

36–46% in males

b)

12–16 g/dL in males

c)

13.5–17.5 g/dL in males

d)

11–13 g/dL in males

53.

Which step best describes the purpose of high-dose chemotherapy in the stem cell transplant process?

a)

Stimulate graft T cells to attack host organs quickly

b)

Eradicate diseased marrow components before infusion

c)

Prime umbilical cord blood to increase platelet counts

d)

Reduce pain perception before anesthesia is administered

54.

A patient develops a pruritic rash and liver dysfunction after allogeneic transplant. Which mechanism most likely explains this complication?

a)

Neutrophils attack infused stem cells directly

b)

Macrophages destroy prophylactic antibiotics

c)

Donor T cells recognize host tissues as foreign

d)

Host T cells reject donor red blood cells

55.

Which source can be used for hematopoietic stem cells besides bone marrow?

a)

Synovial fluid aspirate from large joints

b)

Umbilical cord blood or peripheral blood

c)

Cerebrospinal fluid from lumbar puncture

d)

Peritoneal fluid from paracentesis

56.

During cancer pain assessment, which principle should guide the nurse's decision-making?

a)

Patient self-report is the primary pain source

b)

Opioid need is proven by imaging studies

c)

Objective vital signs outweigh patient self-report

d)

Family report replaces patient verbal ratings

57.

Which regimen best reflects appropriate pharmacologic cancer pain management?

a)

Short trial of antibiotics for neuropathic pain

b)

Around-the-clock dosing with rescue doses

c)

As-needed dosing only without baseline analgesia

d)

Exclusive use of nonpharmacologic measures

58.

A clinician worries about addiction and therefore withholds opioids from a patient with severe cancer pain. What is the most appropriate critique of this decision?

a)

Reasonable because addiction risk is always high

b)

Not valid because under-medication is harmful

c)

Not valid only when using spinal anesthesia

d)

Reasonable if nonsteroidal drugs are available

59.

Which post-transplant complication is most commonly prevented with prophylactic antibiotics?

a)

Bacterial, viral, and fungal infections

b)

Chemotherapy-induced cardiomyopathy

c)

Autoimmune hemolysis after transfusion reactions

d)

Immediate graft failure due to anemia

60.

Which finding most strongly suggests Superior Vena Cava syndrome in a patient with lung cancer?

a)

Painless jaundice with dark urine

b)

Unilateral leg swelling after long airplane travel

c)

Facial and periorbital edema with venous distention

d)

Diffuse abdominal tenderness without guarding

61.

A patient starts chemotherapy and 24 hours later develops weakness, diarrhea, and seizures. Which laboratory pattern best supports Tumor Lysis syndrome?

a)

Hypouricemia, hyperphosphatemia, hyperkalemia, hypercalcemia

b)

Hypouricemia, hypophosphatemia, hypokalemia, hypercalcemia

c)

Hyperuricemia, hypophosphatemia, hypokalemia, hypercalcemia

d)

Hyperuricemia, hyperphosphatemia, hyperkalemia, hypocalcemia

62.

Which immediate management is most appropriate for a suspected Superior Vena Cava syndrome caused by a mediastinal tumor?

a)

Urgent radiation to the obstruction site or chemotherapy

b)

Elective surgical resection after outpatient evaluation

c)

Empiric broad-spectrum antibiotics for seven days

d)

High-dose corticosteroids for long-term monotherapy

63.

Paraneoplastic syndrome from small-cell lung cancer most likely presents with which endocrine or electrolyte abnormality?

a)

Addison disease with chronic hypotension

b)

Graves disease with ophthalmopathy

c)

Primary hyperparathyroidism with low phosphate levels

d)

Syndrome of inappropriate antidiuretic hormone secretion

64.

Which nursing action best reduces infection risk during chemotherapy-induced bone marrow suppression?

a)

Encourage daily jogging in public parks

b)

Teach to avoid large crowds and active infections

c)

Recommend probiotic supplements every morning

d)

Advise high-protein diet without restrictions

65.

A patient on induction chemotherapy has rising potassium and phosphate with decreasing calcium. What complication should you prioritize and what supportive measure helps prevent renal injury?

a)

Tumor Lysis syndrome; aggressive hydration to maintain output

b)

Septic shock; early diuresis with loop diuretics

c)

Adrenal crisis; fluid restriction to prevent edema

d)

SIADH; hypertonic saline for sodium correction

66.

Which factor increases the risk for Superior Vena Cava syndrome aside from tumor burden?

a)

Daily use of low-dose aspirin for prevention

b)

Presence of a central venous catheter in the SVC

c)

High-altitude travel within the last month

d)

Prior appendectomy in early adulthood

67.

Why should electrolytes be closely monitored 6–48 hours after starting cytotoxic therapy in high-tumor-burden cancers?

a)

Drug-induced pancreatitis peaks during the first 48 hours

b)

Delayed neutropenia masks early bacteremia during this period

c)

Rapid cell lysis can cause life-threatening electrolyte derangements

d)

Radiation recall dermatitis is most common at this interval

68.

Which statement best describes video-assisted thoracoscopic surgery (VATS)?

a)

Minimally invasive thoracic procedure using a video scope

b)

Noninvasive imaging test without any incisions

c)

Abdominal laparoscopic operation for gastric cancers

d)

Open thoracic surgery with large rib spreaders used

69.

Primary purpose of a double lumen tracheal tube during thoracic surgery is to

a)

Deliver inhaled chemotherapeutics to both lung fields

b)

Measure airway pressures more accurately during anesthesia

c)

Enable one-lung ventilation and isolate the operative lung

d)

Provide routine postoperative oxygen therapy to both lungs

70.

Targeted cancer therapy most directly aims to

a)

Interact with specific receptors and signaling pathways

b)

Enhance nonspecific immune activation against infections

c)

Increase general cytotoxicity across all dividing cells

d)

Replace damaged tumor DNA with healthy donor sequences

71.

Herceptin (trastuzumab) exerts its antitumor effect primarily by

a)

Inhibiting androgen synthesis in adrenal cortical cells

b)

Stabilizing microtubules to arrest metaphase progression

c)

Alkylating DNA bases to prevent strand separation

d)

Blocking HER2 receptor signaling with a monoclonal antibody

72.

Cisplatin’s principal mechanism of action involves

a)

Neutralizing circulating VEGF to prevent angiogenesis

b)

Forming DNA adducts that miscode and block replication

c)

Inducing apoptosis by blocking estrogen receptors

d)

Inhibiting tyrosine kinase activity at HER2 receptors

73.

Which scenario best justifies selecting a double lumen tracheal tube?

a)

Diagnostic bronchoscopy performed under local anesthesia

b)

Percutaneous nephrolithotomy with limited respiratory impact

c)

Elective hernia repair requiring short general anesthesia only

d)

Thoracoscopic lobectomy requiring isolation of the nonoperative lung

74.

A patient’s tumor is hormone-sensitive and causes inflammatory symptoms. Which combined approach is most appropriate?

a)

Avoid targeted agents because hormones drive all cancers

b)

Switch to nonsteroidal antiandrogens without any adjuncts

c)

Start cisplatin alone to avoid endocrine adverse reactions

d)

Use hormone therapy plus glucocorticoids to reduce side effects