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Bio Review

Total questions: 120

Worksheet time: 6hrs 0mins

Name
Class
Date
1.

During cell respiration, animals take in oxygen and food from the environment and fuel a series of chemical reactions that ultimately produce water and carbon dioxide. Which of the core concepts of biology is exemplified by cell respiration?

a)

Structure and function

b)

Evolution

c)

Pathways and transformations of energy and matter

d)

Systems

e)

Information flow, exchange, and storage

2.

The wing of a flamingo is used for flying, and the flipper of a blue whale is used for swimming. Evidence from the fossil record indicates that both structures were modified from a front limb that was used for walking in a pre-existing ancestor. This is an example of which core concept(s) in biology?

a)

Living systems depend on information transactions

b)

Structure determines function

c)

Evolution explains the unity and diversity of life

d)

Life is subject to chemical and physical laws (systems)

3.

Which level of organization is present in all life forms?

a)

organ

b)

tissue

c)

organelle

d)

cell

4.

The name of the element with 2 electrons, 6 protons, and 7 neutrons is:

a)

carbon

b)

magnesium

c)

nitrogen

d)

fluorine

e)

helium

5.

Which type of bond is shared between an atom of C and and atom of H?

a)

metallic

b)

hydrogen

c)

ionic

d)

nonpolar

e)

polar

6.

What type of interaction is likely to occur between two water molecules or two strands of DNA?

a)

both hydrogen and covalent

b)

covalent

c)

hydrogen

d)

ionic

e)

both hydrogen and ionic

7.

Which of the following statements abput hydrogen bonding is correct?

a)

they have little importance in biology

b)

they involve hydrogen interacting with N, F, or O

c)

they have very strong true bonds that involve two or more metals

d)

they are the bonds that keep O and H together within a single molecule of water

8.

Which of the following sets are LEAST likely to be attracted to each other?

a)

water and an ionic compound (e.g. table salt)

b)

a positive ion and a negative ion

c)

two polar molecules

d)

two nonpolar molecules

9.

What is NOT a characteristic of water that makes it a good candidate for the basis of life on earth?

a)

a molecule of water is completely uncharged and nonreactive

b)

many different compounds will dissolve in water

c)

at typical atmospheric pressure, water can exist as a solid, with a liquid, or a gas

d)

water has high specific heat (i.e. it takes a lot of energy to heat up water)

10.

Two molecules with identical molecular formulas but different structures are called:

a)

monomers

b)

polymers

c)

isomers

d)

dimers

11.

Amphipathic molecules:

a)

do not tend to interact with other molecules

b)

have hydrophilic but not hydrophobic properties

c)

have both hydrophilic and hydrophobic properties

d)

have neither hydrophilic nor hydrophobic properties

e)

have hydrophobic but not hydrophilic properties

12.

What feature of carbon is important for its ability to produce a wide variety of organic molecules?

a)

carbon bonds are not breakable in the range of temperatures associated with life

b)

carbon can form both polar and nonpolar covalent bonds with various elements

c)

carbon can form up to two total bonds

d)

carbon bonds are the strongest bonds on earth

e)

carbon can form hydrogen bonds with water

13.

A monomer contains the following components: a phosphate group, a 5-carbon sugar, and a nitrogen-containing base. Joining together multiple of these monomers into a poly results in which of the following?

a)

a uracil

b)

a lipid

c)

a protein

d)

a carbohydrate

e)

a nucleic acid

14.

A disaccharide, such as maltose, consists of two molecules of glucose linked by what type of bond?

a)

phosphodiester

b)

peptide

c)

glycosidic

d)

hydrogen

15.

The polymer pictured below is made up of multiple fatty acids. It falls into which of the following categories?

a)

carbohydrate

b)

nucleic acid

c)

lipid

d)

protein

16.

Which of the following types of cells lack(s) a nucleus?

a)

fungi

b)

plant

c)

bacteria

d)

animal

17.

Which is the most likely pathway taken by a newly synthesized protein that will be secreted by a cell?

a)

nucleus -> ER -> golgi

b)

ER -> golgi -> vesicles that fuse with plasma membrane

c)

ER -> lysosomes -> vesicles that fuse with plasma membrane

d)

free ribosome -> nucleus -> golgi

18.

Which of the following correctly lists the order of the proposed phases of the origins of life on earth?

a)

cellular functions arise in RNA world, origin of organic molecules, enclose polymers, origin of polymers

b)

origin of organic molecules, origin of polymers, enclose polymers, cellular functions arise in the RNA world

c)

cellular functions arise in the RNA world, origin of organic molecules, origin of polymers, enclose polymers

d)

enclose polymers, origin of polymers, origin of organic molecules, cellular functions arise in the DNA world

e)

origin of organic molecules, enclose polymers, origin of polymers, cellular functions arise in the RNA world

19.

Three ways that plant cells are different than animal cells are the presence of __________, __________, and __________.

a)

chloroplasts, vacuoles, cell walls

b)

plasma membrane, chloroplasts, nucleus

c)

mitochondria, cell walls, plasma membrane

d)

rough ER, cell wall, nucleus

20.

Which of the follwoing are found in bacterial cells? Check all that apply.

a)

plasma membrane

b)

mitochondria

c)

chloroplasts

d)

ribosomes

e)

DNA

21.

Which of the following components could NOT be found in an animal cell?

a)

lysosome

b)

cytopskeleton

c)

cell wall

d)

mitochondria

22.

Which of the following factors would increase membrane fluidity?

a)

a smaller portion of phosphorylated nucleotides

b)

a smaller portion of peripheral proteins

c)

a greater portion of unsaturated phospholipids

d)

a greater portion of transmembrane proteins

23.

What property allows O2 and CO2 to cross a lipid bilayer without the help of membrane proteins?

a)

they are both small, nonpolar molecules

b)

they are both uncharged molecules

c)

they are both large, complex molecules

d)

they are both polar molecules

24.

Water held behind a dam would best reflect:

a)

kinetic energy

b)

mechanical energy

c)

heat energy

d)

potential energy

e)

chemical energy

25.

In the reaction A- + B -> A + B-,

a)

molecule A is reduced and molecule B is oxidized

b)

molecule A and B are both reduced

c)

molecule A is oxidized and molecule B is uncharged

d)

molecules A and B are both oxidized

e)

molecule A is oxidized and molecule B is reduced

26.

In photosynthesis, carbon dioxide gas is reduced and combined to form glucose. This is an example of:

a)

cannabolism

b)

embolism

c)

anabolism

d)

catabolism

27.

You measure the amount of enzyme activity in the presence of compound X and notice that enzyme activity decreases. You note that as you add more substrate the amount of enzyme activity increases. This indicates that the compound X is a(n)

a)

enzyme

b)

activator

c)

competitive inhibitor

d)

non-competitive inhibitor

28.

Why is ATP an important molecule in metabolism?

a)

its terminal phosphate has higher energy than the other two

b)

all reactants in cells are catalyzed by ATP

c)

it provides energy coupling between exergonic and endergonic reactions

d)

its hydrolysis creates oxidative phosphorylation

29.

The following question is based on the reaction shown above A + B --> C + D with and without an enzyme.

Which of the following represents the activation energy required for the reactants to reach the transition state and convert the reactants to products in the presence of the enzyme?

a)

e

b)

b

c)

d

d)

a

e)

c

30.

What are the net products of glycolysis?

a)

2 ATP, 1 glucose, 2 pyruvate

b)

4 ATP, 6 phosphate groups, 6 carbons

c)

4 ATP, 2 NADH, 2 pyruvate

d)

2 ATP, 2 NADH, 2 pyruvate

31.

Which of the following statements is TRUE of both aerobic and anaerobic respiration?

a)

both use glycolysis to oxidize glucose to pyruvate and both produce NADH as high-energy intermediates.

b)

both produce ethanol

c)

both require oxygen to oxidize glucose to pyruvate

d)

both require a functional mitochondrion

32.

Respiration is measured in a human. How do the concentration of O2 AND CO2 in inhaled air compare with exhaled air?

a)

inhaled air has less O2 AND CO2 than exhaled air

b)

inhaled air has more O2 and CO2 than exhaled air

c)

inhaled air has less O2 and CO2 than exhaled air

d)

inhaled air has more O2 and less CO2 than exhaled air

33.

In chemiosmosis in the chloroplast, protons flow from the thylakoid space into the stroma to provide the enrgy to make ATP via the ATP synthase. In what direction do protons flow during chemiosmosis in the mitochondria to make ATP?

a)

from the matrix to the stroma

b)

from the intermembrane space to the cytosol

c)

from the intermembrane space to the matrix

d)

from the matrix to the cytosol

34.

In the equation, C6H12O6 + 6O2 --> 6CO2 + 6H2O, on which side of the reaction would you find ATP and heat?

a)

ATP AND heat would be products because this is an exergonic reaction

b)

ATP and heat could appear on either side because this reaction is in equilibrium

c)

ATP and heat would be reactants because this is an exergonic reaction

d)

ATP and heat would be reactants because this is an endergonic reaction

e)

ATP and heat would be products because this is an endergonic reaction

35.

The equation C6H12O6 + 6O2 --> 6CO2 + 6H2O is a summary equation for which of the following process?

a)

photosynthesis

b)

cellulose biosynthesis

c)

cellular respiration

d)

lipid biosynthesis

36.

A comparison of mitochondria and chloroplasts shows that:

a)

they have very different electron transport protein complexes

b)

both use oxygen as a final electron transporter

c)

both generate ATP via an H+ gradient

d)

only mitochondria contain ATP synthase

37.

In the reaction, 6CO2 + 6H2O --> C6H12O6 + 6O2, which side should energy be placed on?

a)

the left side; this is an exergonic reaction

b)

the left side; this is an endergonic reaction

c)

the right side; this is an exergonic reaction

d)

the right side; this is an endergonic reaction

38.

How is the water necessary for photosynthesis used?

a)

to combine with ADP forming ATP

b)

as an electron donor

c)

as a substrate for ATP synthase

d)

as an electron acceptor

39.

Which of the following molecules are products of the light reactants of photosynthesis and are used in the catabolic reactions of the Calvin Cycle?

a)

H+ and electrons

b)

CO2 and H2O

c)

O2 and H2O

d)

ATP, NADPH

40.

Placing celery sticks in fresh water will make them more turgid and harder. This is because

a)

the celery cells are isotonic to fresh water

b)

the celery sticks are hypotonic to fresh water

c)

water moves from the celery cells into fresh water

d)

the celery cells are hypertonic to fresh water

41.

What is meant by the description "antiparallel" regarding the strands that make up DNA?

a)

one strand contains only purines and the other contains only pyrimidines

b)

the 5' to 3' direction of one strand runs counter/opposite to the 5' to 3' direction of the other strand

c)

the twisting nature of DNA creates nonparallel strands

d)

base pairings create unequal spacing between the two DNA strands

42.

Which of the following experimental approaches proved DNA is the genetic material?

a)

purify different types of macromolecules (DNA, RNA protein) from lethal bacteria (a strain that kills mice) and test which macromolecules is capable of transforming non-lethal bacteria into lethal bacteria

b)

determine the structure of different macromolecules using x-ray diffraction

c)

heat kill lethal bacteria (a strain that kills mice) and incubate the dead bacteria with live bacteria of a non-lethal strain

d)

use radiolabeled nucleotides to show that they are semi-conservatively incorporated into DNA

43.

Rosalind Franklin's important contribution to solving the structure of DNA was:

a)

discovering that the number of adenines matches the number of thymines in all genomes

b)

obtaining x-ray diffraction data that revealed the double helix structure

c)

piecing together "ball and stick" models of nucleotides to form a double helix

d)

transformation of R-type bacteria with DNA S-type bacteria

44.

What happens to RNA primers during DNA replication?

a)

a RNA transisomerase converts the RNA into DNA

b)

RNA can't base pair with DNA, so the RNA primer doesn't stay associated with the template DNA

c)

a DNA polymerase removes the RNA primer and replaces it with DNA

d)

the nucleotide excision repair pathway removes the RNA primer

45.

Which of the following statements about Origins of Replication is FALSE?

a)

in eukaryotes, multiple origins of replication form along a chromosme

b)

origins of replication are bidirectional

c)

in eukaryotes, a single origin of replication forms at one telomere and spreads toward the opposite telomere so that only one origin of replication is required to replicate a chromosome

d)

each replication fork contains a leading strand and a lagging strand

46.

Which of the following best describes the function of telomerase at the telomere?

a)

it makes special primers that do not need to be removed from the lagging strand

b)

it adds repeats of a specific DNA sequence to the 3' end of the template strand of DNA

c)

it allows DNA polymerase to add a polyA tail (many A nucleotides) to the end of chromosomes without any template sequence

d)

it adds a random sequence of nucleotides to the 3' end the newly synthesized "daughter" strands of DNA

47.

The protein that separates DNA strand at the replication fork is

a)

DNA ligase

b)

DNA helicase

c)

DNA primase

d)

DNA polymerase

48.

A gene whose promoter is located within "tightly condensed chromatin" (also known as heterochromatin) is likely to:

a)

not be copied during RNA replication

b)

not be transcribed

c)

be found within the telomere region at the end of chromosomes

d)

be transcribed

49.

An octamer of histone proteins with 147 base pairs of DNA wrapped around it forms:

a)

an enhancer domain

b)

a telomere

c)

a nucleosome

d)

looped regions of chromosomes

50.

Which of the following is necessary to compact the "beads-on-a-string" form of DNA into the "30-nm fiber" form"?

a)

chromatin remodeling enzymes

b)

chromosome looping

c)

telomerase

d)

histone H1 binding "linker" regions of DNA

51.

How many nucleotides are in a codon?

a)

three

b)

two

c)

one

d)

four

52.

What mRNA sequence will be transcribed from this DNA template sequence: 3' - TTCGGACTA - 5'

a)

5' - UAGUCCGAA - 3'

b)

3' - UUCGGACUA - 5'

c)

5' - AAGCCUGAU - 3'

d)

3' - AUCAGGCUU - 5'

53.

Transcription begins at a site in the DNA called the

a)

transcription unit

b)

core promoter

c)

response element

d)

enhancer

54.

What process enables a single gene to encode two or more polypeptides that are different in their amino acid sequence?

a)

spliceosome jumping

b)

capping

c)

alternative splicing

d)

reverse transcription

55.

mRNA processing in eukaryotes (including 5' cap addition and splicing), occurs;

a)

only after Dicer converts the RNA from double stranded to single stranded

b)

in the cytoplasm

c)

in the nucleus

d)

only after ribosomes bind the mRNA

56.

The genetic code is considered "degenerate" or "redundant" because:

a)

every amino acid is encoded by only one codon

b)

amino acids are encoded by more than one codon

c)

codons contain uracil (U) instead of thymine (T)

d)

there is more than one amino acid - there are 20

57.

In which of the ribosomal sites, the A site, P site, and/or E site, could a tRNA with an attached polypeptide (protein with multiple amino acids) be found at the beginning of the Elongation stage?

a)

E site

b)

A site

c)

P site

d)

A and E sites

58.

What occupies the ribosome "A" site when the codon in the "A" site is UAA?

a)

tRNAs that are not charged with an amino acid

b)

any tRNA charged with Met

c)

nothing - the A site is not filled when that codon is present

d)

release factor protein

59.

At the beginning of each round of Translation Elongation, what best describes tRNA in the A site?

a)

the tRNA recognizes a stop codon

b)

the tRNA does not have an amino acid attached

c)

the tRNA has the growing polypeptide attached

d)

the tRNA has a single amino acid attached

60.

Which of the following is NOT a property of the genetic code?

a)

it specifies the amino acids within a polypeptide

b)

it is composed of codons, which are specific sequences of three bases

c)

it has a start codon, which specifies the starting point of the polypeptide synthesis

d)

it determines the rate of transcription

61.

Which sequence of events CORRECTLY describes the initiation and elongation steps of translation in bacteria?

(1) initiator tRNA binds start codon on mRNA

(2) small ribosomal subunit binds to mRNA

(3) large ribosomal subunit binds

(4) tRNA entry and peptidyl transfer reaction

(5) translocation of ribosome and release of tRNA

a)

2, 3, 1, 5, 4

b)

1, 2, 3, 5, 4

c)

1, 3, 2, 4, 5

d)

2, 1, 3, 4, 5

62.

The Exit Site of "E" in a ribosome is where:

a)

the tRNA that adds the next amino acid enters the ribosome

b)

the 5' end of the mRNA has already been translated exits the ribosome

c)

the finished polypeptide exits the ribosome

d)

the tRNA that was previously in the P site and no longer has any amino acid attached exits the ribosome

63.

Cell type-specific regulation of gene transcription typically requires:

a)

mutations that cause different DNA sequences in each cell type

b)

loss of a DNA repair pathway in one of the cell types

c)

cell-type specific exons within the gene

d)

combinations of DNA sequence elements (enhancers and silencers) in the promoter/regulatory region

64.

The collagen gene is transcribed in fibroblast cells but is never transcribed in neurons. This differential transcription could be regulated by:

a)

a transcription factor (activator) that is only expressed in fibroblasts and binds to an enhancer DNA sequence (regulatory element) in the collagen promoter

b)

the absence of a core promoter in the collagen gene of neurons

c)

an enhancer DNA sequence (regulatory element) that is only present in the collagen promoter of fibroblasts

d)

a silencer DNA sequence (regulatory element) that is only present in the collagen promoter of neurons

65.

At the lac operon, when lactose and glucose are present at low level:

a)

cAMP levels are high and CAP is able to activate very high rates of transcription

b)

the rate of transcription is low but the lactose permease gene is not included in the polycistronic mRNA

c)

the rate of transcription is very low because the lac repressor binds to its target sequence (the operator)

d)

RNA polymerase is able to bind to the operator so the rate of transcription is very high

66.

Which statement best describes why multicellular eukaryotes typically use more complex combinations of regulatory elements to control gene transcription compared to bacteria?

a)

the complexity ensures that all mRNAs are translated - in bacteria only a portion of mRNAs are translated

b)

the complexity allows precise control over the timing of transcription and the type of cell where transcription occurs

c)

the complexity allows each cell type to have different DNA sequences

d)

the complexity is caused by DNA mutations that don't occur in bacteria

67.

Which of the following statements about chromatin is TRUE?

a)

nucleosome are not considered part of chromatin

b)

chromatin modifications only occur during DNA replication

c)

chromatin is only found in the protein coding portions of genes

d)

histones are a major component of chromatin

68.

If lacl were mutated so that the Lac Repressor ALWAYS binds to the operator DNA sequence (regardless of small effector molecule levels), this would cause:

a)

the Lac operon would we transcribed at very high rates when lactose levels are low and glucose levels are high

b)

the lac operon would be transcribed at very low rates when lactose levels are low, but would be transcribed at very high rates when lactose levels are high

c)

the Lac operon would be transcribed at very high rates when lactose and glucose levels are low

d)

the Lac operon would always be transcribed at very low rates, the levels of lactose and glucose would not matter

69.

Fibroblast cells (a eukaryotic cell type) contain 1,000 different proteins. You predict that "Gene X" is important for fibroblast development and delete the gene (the entire gene is removed from the genome). You discover that fibroblasts lacking Gene X now contain only 997 proteins. The three missing proteins contain an identical domain but other amino acid sequences are unique to each protein. This result could be explained by:

a)

a missense mutation in Gene X

b)

alternative splicing of Gene X pre-mRNA

c)

Gene X being located in a nucleosome free region

d)

Three different ribosome binding sites in the Gene X mRNA

70.

To produce multiple proteins from a polycistronic mRNA, each translated region must have:

a)

a ribosome binding site, a start codon, a stop codon

b)

a start codon, a stop codon

c)

a splice site before the next protein coding region

d)

a start codon, a stop codon, a termination sequence

71.

Differential gene expression between two cell types could occur because:

a)

all of these are correct

b)

a transcription activator in one cell type but not the other

c)

a histone modifying enzyme is present in one cell type but not the other

d)

alternative splicing skips an exon in one cell type but not the other

72.

Which of the follwoing is an example of a somatic mutation? select all that apply.

a)

a mutation in an adult neuron

b)

a mutation in an egg cell

c)

a mutation in a sperm cell

d)

a mutation in an embryonic muscle cell

73.

A deletion occurs during DNA replication, causing the underlined guanine (also shown in red) to be removed from the coding strand of a gene. What effect is this most likely to have on the final protein?

5' ATG CGG GTA GTT AGC CGA TAG 3'

a)

the deletion will cause a single amino acid chnage

b)

the deletion will cause a silent mutation - the protein won't change in any way

c)

the deletion will cause a frameshift and introduce a premature stop codon - the resulting protein will be shorter than normal

d)

the deletion will cause a frameshift that removes a stop codon - the resulting protein will be longer than normal

74.

In which of the following locations is a mutation least likely to affect gene function?

a)

core promoter

b)

an intergenic region between genes

c)

protein coding region

d)

regulatory site such as an enhancer

75.

A mutation in a gene in the fruit fly Drosophila was found to affect eye color. The relevant protein is normal in its molecular weight and amino acid sequence (in other words, nothing changes about the protein), but much less of the protein is made in mutant flies. A reasonable explanation for the change in levels of protein is that the mutation:

a)

introduces a premature stop codon

b)

is in a splice site and causes alternative splicing of the pre-mRNA

c)

causes a frameshift

d)

is in the core promoter of the gene

76.

Which of the following is an example of a spontaneous DNA mutation ( a mutation that is caused by normal metabolic byproducts produced in a cell)?

a)

reverse transcriptase enzymes convert thymine (T) to uracil (U)

b)

nitrous oxide converts cytosine (C) to uracil (U)

c)

ultraviolet (UV) light from the sun causes thymine dimers

77.

True of False: DNA mutations only occur during replication, when the DNA polymerase adds an incorrect nucleotide

a)

true

b)

false

78.

Which of the following statements correctly describes the error rate of DNA replication?

a)

errors are common - the rate is around 1 out of every 1 thousand nucleotides

b)

the error is very low but not zero - the rate is around 1 out of every 1 billion nucleotides

c)

the error rate is zero, it is impossible for DNA polymerase to add an incorrect nucleotide

79.

What would happen if actively dividing cells were treated with a chemical that inhibits telomerase activity during each round of cell division?

a)

okazaki fragments could not be properly joined together

b)

the ends of chromosomes would become shorter (DNA sequence would be lost) after each round of DNA replication

c)

origins of replication could not form in the middle of the chromosome

d)

large portions of the middle of chromosomes would be single-stranded

80.

What was the surprising finding from Griffith's work with mice and pneumonia-causing bacteria in 1928?

a)

heat killed pathogenic cells (S cells) caused pneumonia and killed mice

b)

a heritable substance from heat killed pathogenic bacteria (S cells) transformed nonpathogenic bacteria (R cells) making them lethal (the transformed bacteria killed mice)

c)

nonpathogenic cells (R cells) plus pathogenic S-cell mRNA caused pneumonia and killed mice

d)

nonpathogenic cells (R cells) plus pathogenic S-cell proteins caused pneumonia and killed mice

81.

Which of the following statements about sister chromatids is TRUE?

a)

all answers are correct

b)

sister chromatids are produced during metaphase

c)

sister chromatids are held together bby complementary base pairing of DNA

d)

sister chromatids are exact copies of each other and are formed before the M phase begins

e)

sister chromatids contain the same genes, but they may have different alleles because they come frim different biological parents

82.

The presence of cell walls in plants is associated with _______ in telophase.

a)

cell plate formation

b)

cleavage furrows

c)

differentiation

d)

spindle fiber formation

83.

Place the following events of mitosis in the correct order.

I. The cleavage furrow forms

II. Sister chromatids align on the metaphase plate

III. The mitotic spindle forms and spindle microtubules attach to sister chromatids

IV. Sister chromatids seperate

V. Chromosomes begin to condense

a)

I, V, II, III, IV

b)

V, III, II, IV, I

c)

V, II, III, IV, I

d)

V, IV, III, II, I

e)

III, V, IV, II, I

84.

Compared to the mother cell, daughter cells at the end of mitosis have ________ number of chromosomes.

a)

the same

b)

twice the

c)

half of the

d)

two more than the original

85.

What is a likely advantage of sexual reproduction over asexual reproduction?

a)

there is a lower chance of using up the resources in a given environment

b)

sexual reproduction is more cost-effective

c)

sexual reproduction results in variation in the offspring

d)

sexual reproduction involves fewer stages

86.

Bivalents, also known as tetrads align in the middle of the cell during

a)

anaphase of Meiosis II

b)

anaphase of Mitosis

c)

metaphase of Meiosis II

d)

metaphase of Meiosis I

e)

anaphase of Meiosis I

87.

Which of the following processes do not lead to variation in offspring with the same parents?

a)

random or independent assortment of chromosomes

b)

random joining of sperm and egg

c)

chromosomal duplication

d)

crossing over

88.

A human zygote has a(n) _______ number of chromosomes.

a)

tetraploid

b)

polypoid

c)

haploid

d)

diploid

89.

Which of the following events does not occur during some stage of interphase?

a)

cell growth and elongation

b)

DNA duplication

c)

separation of sister chromatids

d)

passing through the G1 checkpoint

90.

Which of the following is NOT a checkpoint that controls the progression of the cell cycle?

a)

the metaphase checkpoint determines if all chromosomes are attached to the spindle apparatus

b)

the G2 checkpoint checks for DNA damage and determines if all of the DNA is replicated

c)

the G1 checkpoint checks for proper cell size and nutrients for the S phase

d)

cytokinesis involves the formation of cleavage furrow to separate the cells

91.

Which of the following statements about the cell cycle is correct?

a)

In actively dividing cells, the S and G2 phases are collectively known as interphase.

b)

The phases of the cell cycle are G1, S, and M phases.

c)

During G2 phase, the cell grows and copies its chromosomes in preparation for cell division.

d)

When S phase is finished, chromosome duplication is complete.

92.

What does the term monohybrid cross mean?

a)

a monohybrid cross involves organisms that are heterozygous for one character

b)

a monohybrid cross produces a single offspring

c)

a monohybrid is performed for one generation

d)

a monohybrid cross involves a single parent

93.

Th expression of genes is called the _______.

a)

phenotype

b)

genotype

c)

karyotype

d)

pedigree

94.

How many alleles do diploid organisms package into their gametes for each of their genes?

a)

1

b)

4

c)

2

d)

3

95.

Which is the best definition of different alleles?

a)

different DNA sequences found at the same locus on sister chromatids

b)

different DNA sequences found at the same locus on homologous chromosomes

c)

different phenotypes for a particular character

d)

different particles found in gametes

96.

When a homozygous dominant individual is crossed with a homozygous recessive individual in the parental (P) generation, what is the phenotypic ratio of the F2 offspring (ratio is written as dominant phenotype:recessive phenotype)?

a)

1:2

b)

3:1

c)

1:3

d)

1:2:1

e)

2:1

97.

Should a genetic abnormality arise, ______ prevent a cell from progressing uncontrollably through the cell cycle.

a)

spindle proteins

b)

checkpoint proteins

c)

allelease enzymes

d)

DNA synthases

98.

The accumulation of mutations and epigenetic changes in a lineage of cells that leads to uncontrolled cell growth is called ________.

a)

cancer

b)

dosage compensation

c)

a Barr body

d)

a tumor suppressor

99.

CRISPR/Cas-based genome editing involves what normal process in a cell?

a)

the pathways that add telomere sequences at the end of chromosomes

b)

the 3'-5' exonuclease activity of DNA polymerase

c)

the pathways that repair double-stranded DNA breaks

d)

the reverse transcriptase pathway that converts RNA into DNA

100.

"Next Generation" DNA sequencing technology is different from previous/ "older" DNA sequencing techniques in what way?

a)

it is only able to "read" eukaryotic DNA sequences

b)

it requires cloning DNA sequences into a bacterial vector

c)

it doesn't use any nucleotides to generate a complementary DNA sequence

d)

it can "read" more than 100 million DNA sequences all at the same time

101.

Why are fluorescently-labeled ddNTPs used for sequencing?

a)

the fluorescent signal is used to identify the last nucleotide added to the different sized DNA-fragments

b)

the fluorescent signal is used to identify vectors that contain the cloned DNA

c)

the fluorescent signal is used to distinguish template RNA from newly made DNA

d)

the fluorescent signal is used to confirm that DNA synthesis is occuring

102.

The dideoxy chain termination sequencing method uses what enzyme?

a)

DNA polymerase

b)

Topoisomerase

c)

Reverse Transcriptase

d)

RNA polymerase

103.

An XY individual is colorblind. Which of the following must be true? Recall that the allele for colorblindness is represented as XC

a)

this person's father, an XY individual, was colorblind

b)

this person's mother, an XX individual, had at least one XC allele

c)

100% of this person's offspring will be colorblind

d)

this person's mother, an XX individual, was colorblind

104.

In mammals, dosage compensation happens via

a)

X chromsome inactivation

b)

Y chromosome inactivation

c)

X/Y chromosome triploidy

d)

X chromosome apoptosis

e)

Y chromosome duplication

105.

If AaBb is crossed with aabb, what proportion of the offspring would be expected to be aabb?

a)

4 in 16

b)

8 in 16

c)

2 in 16

d)

1 in 16

106.

Genetically identical plants are grown in the same soil with the same amount of light, but put into rooms that are set 75, 80, 85, or 90 degrees. The plants grown at 85 degrees are always significantly taller than those grown at any of the other temperatures. This is an example of

a)

some plants having stronger height genes than others

b)

the different plants having different genes for height

c)

plant height not being an inherited trait

d)

the environment affecting the expression of the gene(s) that control the height of the plants

e)

errors in height measurement

107.

The discovery that there are homologous Hox genes in nearly all animals suggests that

a)

Hox genes are not important if they are in all animals

b)

animal development is a simple process that can use any duplicated gene to pattern an embryo

c)

DNA replication is defective in animals and makes many mistakes

d)

the last common ancestor of all animals used Hox genes to pattern its body

108.

Which of the following is NOT a beneficial characteristic of developmental model of organisms?

a)

sequenced genome

b)

produce many offspring

c)

transparent embryos

d)

long life span

109.

A true-breeding pea plant with smooth pods is crossed to a true-breeding pea plant with constricted pods. The offspring of this cross all have smooth pods. This indicated that (select all that apply)

a)

constricted and smooth are not alleles

b)

constricted and smooth are variants of the same gene

c)

smooth is dominant and constricted is recessive

d)

constricted is dominant and smooth is recessive

110.

Two black female mice (Z and W) are crossed with the same brown male. In a number of litters female Z produced 9 black mice and 7 brown mice and female W produced 14 black mice. What are the possible genotypes of the parents?

a)

Female Z = Bb; Female W = bb; Male = bb

b)

Female Z = Bb; Female W = BB; Male = bb

c)

Female Z = BB; Female W =Bb; Male = BB

d)

Female Z = Bb; Female W = BB; Male = Bb

111.

Which of the following describe a body axis displayed by Arabidopsis thaliana, a popular plant model system?

a)

dorsal-ventral

b)

left-reight

c)

anterior-posterior

d)

root-shoot

112.

Pattern formation in animal and plant embryos is controlled by

a)

the activation of a series of homologous enzymes

b)

a hierarchy of cell-type specific transcription factors

c)

gametogenesis which produces the oocyte and the sperm

d)

stem cells which are induced by signaling factors

113.

X chromosome inactivation occurs

a)

very early in development, but after multiple rounds of cell division

b)

in adult offspring of heterozygotes only

c)

only in XY individuals

d)

immediately after fertilization at the one cell stage

114.

Mutations in which of the following genes lead to transformations in the identity of entire body parts?

a)

egg-polarity genes

b)

homeotic genes

c)

general transcription factor genes

d)

segmentation genes

115.

A stem cell that can give rise to any type of cell of an embryo and produce extraembryonic tissue such as the amnion is called

a)

multipotent

b)

unipotent

c)

totipotent

d)

pluripotent

116.

If W = purple flower and w = white, and D = tall plants and d = short plants, a wwDd plant would be

a)

purple and short

b)

white and short

c)

white and tall

d)

purple and tall

117.

Every gamete from a diploid parent with a homozygous dominant genotype for a certain gene has

a)

one dominant allele for this gene

b)

both alleles for this gene

c)

either one dominant or one recessive allele for this gene

d)

one recessive allele for this gene

118.

A plant with white flowers is crossed to a plant with dark purple flowers, and the F1 generation is 100% plants with light purple flowers. What is the expected phenotypic ratio for the F2 generation (two F1 plants crossed to each other)?

a)

50% dark purple: 50% white

b)

75% dark purple: 25% white

c)

100% dark purple

d)

25% white: 50% light purple: 25% dark purple

119.

An XX individual who has blood type A has a XX offspring who is blood type O and a XY offspring who is type B. Which of the following is a possible blood type phenotype for the other parent?

a)

A blood type

b)

B blood type

c)

O blood type

d)

AB blood type

120.

What would happen if only dideoxyribonucleotides were used in sequencing (instead of a mixture of deoxyribonucleotides (regular dNTPs) and dideoxyribonucleotides (ddNTPs)?

a)

no nucleotides would be added to the primer

b)

the DNA wouldn't have a negative charge and couldn't be separated by electrophoresis

c)

DNA synthesis would never stop and the DNA produce would be too long for sequencing

d)

DNA synthesis would always stop after adding the first nucleotide to the primer