wayground logo

Free Printable Worksheets

Font size

S
M
L
XL
Worksheets

A&P II Midterm Review

Total questions: 67

Worksheet time: 35mins

Name
Class
Date
1.

State how many organ systems are in the human body.

a)

10 organ systems

b)

11 organ systems

c)

12 organ systems

d)

13 organ systems

2.

Define anatomy.

a)

Study of the functions of body parts

b)

Study of the structure and organization of body parts

c)

Study of disease processes

d)

Study of chemical reactions in cells

3.

Define physiology.

a)

Study of the structure of tissues

b)

Study of the functions of body parts and how they work

c)

Study of hereditary traits

d)

Study of external body landmarks

4.

Explain the difference between anatomy and physiology.

a)

Anatomy studies function; physiology studies structure

b)

Anatomy studies structure; physiology studies function

c)

Anatomy and physiology both study only cells

d)

Anatomy and physiology are different names for pathology

5.

Choose the correct order of levels of organization in the human body from smallest to largest.

a)

Atom → molecule → cell → tissue → organ → organ system → organism

b)

Molecule → atom → tissue → organ → cell → organ system → organism

c)

Cell → atom → molecule → tissue → organ → organism → organ system

d)

Atom → cell → molecule → tissue → organ system → organ → organism

6.

Match each organ system to a basic function.

a)

Integumentary

1.

Protects body, helps regulate temperature, prevents water loss

b)

Skeletal

2.

Provides support and protection; stores minerals

c)

Muscular

3.

Produces movement and heat

d)

Cardiovascular

4.

Transports gases, nutrients, wastes, and hormones

e)

Respiratory

5.

Exchanges gases to supply oxygen and remove carbon dioxide

7.

Define homeostasis.

a)

Maintenance of a stable internal environment despite external changes

b)

Process of breaking down food to release energy

c)

Ability of an organism to reproduce

d)

Increase in body mass over time

8.

Explain why homeostasis is necessary for survival.

a)

It allows cells to function optimally by keeping internal conditions within narrow limits

b)

It maximizes growth rate regardless of environmental conditions

c)

It ensures pathogens are eliminated without immune responses

d)

It prevents any change in body temperature under all circumstances

9.

Define negative feedback.

a)

A response that amplifies the original stimulus

b)

A response that opposes and reduces the original stimulus to restore normal conditions

c)

A response that is unrelated to the original stimulus

d)

A response that permanently shuts down the controlled variable

10.

Define positive feedback.

a)

A response that reduces the original stimulus to restore balance

b)

A response that increases and reinforces the original stimulus

c)

A response that has no effect on the original stimulus

d)

A response that always lowers body temperature

11.

Select the examples that typically operate by negative feedback.

a)

Thermoregulation of body temperature

b)

Blood sugar regulation by insulin and glucagon

c)

Hormone release during childbirth

d)

Platelet activation during blood clotting

12.

Choose the accurate statements about feedback mechanisms.

a)

Negative feedback restores the body to normal by counteracting change

b)

Positive feedback increases the original stimulus

c)

Negative feedback always leads to runaway processes

d)

Positive feedback is primarily used for long-term homeostasis

13.

Identify the correct description of the anatomical position.

a)

Body standing upright, facing forward, feet together, arms at sides, palms facing forward

b)

Body lying prone, head turned left, knees bent, palms facing thighs

c)

Body standing upright, arms crossed over chest, palms facing thighs

d)

Body sitting with legs extended, palms facing backward

14.

Explain why the anatomical position is important.

a)

It standardizes reference for directions and locations on the body

b)

It optimizes athletic performance

c)

It prevents injury during medical procedures

d)

It eliminates the need for directional terminology

15.

Match directional terms to their correct meaning.

a)

Anterior

1.

Toward the front of the body

b)

Posterior

2.

Toward the back of the body

c)

Superior

3.

Above; toward the head

d)

Inferior

4.

Below; away from the head

16.

Match directional terms to their correct meaning.

a)

Medial

1.

Toward the midline

b)

Lateral

2.

Away from the midline

c)

Proximal

3.

Closer to the point of attachment or origin

d)

Distal

4.

Farther from the point of attachment or origin

17.

Distinguish between simple and stratified epithelium.

a)

Simple epithelium has one cell layer; stratified epithelium has multiple layers

b)

Simple epithelium has multiple layers; stratified epithelium has one layer

c)

Both have the same number of cell layers

d)

Neither has organized layers

18.

Distinguish between stratified and pseudostratified epithelium.

a)

Stratified epithelium appears layered because nuclei are at different heights but all cells contact the basement membrane

b)

Pseudostratified epithelium has multiple true layers with only basal cells contacting the basement membrane

c)

Stratified epithelium has one cell layer; pseudostratified has two

d)

Pseudostratified epithelium appears layered but all cells contact the basement membrane

19.

Identify the epithelial tissue type characterized by thin, flat cells adapted for diffusion.

a)

Simple cuboidal epithelium

b)

Stratified squamous epithelium

c)

Simple squamous epithelium

d)

Transitional epithelium

20.

Identify the epithelial tissue type that is suited for secretion and absorption in glands and kidney tubules.

a)

Simple cuboidal epithelium

b)

Stratified columnar epithelium

c)

Pseudostratified columnar epithelium

d)

Simple squamous epithelium

21.

Identify the epithelial tissue type that protects against abrasion in the skin and oral cavity.

a)

Simple columnar epithelium

b)

Stratified squamous epithelium

c)

Simple cuboidal epithelium

d)

Transitional epithelium

22.

Identify the epithelial tissue type that lines much of the respiratory tract and moves mucus via cilia.

a)

Pseudostratified columnar epithelium

b)

Stratified columnar epithelium

c)

Simple squamous epithelium

d)

Transitional epithelium

23.

Identify the epithelial tissue type that stretches to accommodate fluctuations in bladder volume.

a)

Transitional epithelium

b)

Simple columnar epithelium

c)

Stratified cuboidal epithelium

d)

Simple squamous epithelium

24.

Match connective tissue types to characteristic features.

a)

Adipose

1.

Stores energy in fat cells; cushions organs

b)

Dense regular connective tissue

2.

Collagen fibers aligned for tensile strength in tendons/ligaments

c)

Hyaline cartilage

3.

Smooth matrix with chondrocytes; supports with flexibility

d)

Fibrocartilage

4.

Thick collagen bundles; resists compression in intervertebral discs

e)

Bone

5.

Rigid, calcified matrix with osteocytes; supports and protects

25.

Identify the connective tissue that is a fluid with cells suspended in plasma and functions in transport.

a)

Elastic cartilage

b)

Areolar (loose) connective tissue

c)

Blood

d)

Dense irregular connective tissue

26.

Muscle Tissue — You should be able to identify: Which muscle tissue is striated and under voluntary control?

a)

Cardiac muscle

b)

Smooth muscle

c)

Skeletal muscle

d)

Visceral muscle

27.

Muscle Tissue — You should be able to identify: Which muscle tissue has intercalated discs and is found only in the heart?

a)

Smooth muscle

b)

Skeletal muscle

c)

Cardiac muscle

d)

Multiunit smooth muscle

28.

Muscle Tissue — You should be able to identify: Which muscle tissue is non‑striated and controls movements such as peristalsis?

a)

Skeletal muscle

b)

Smooth muscle

c)

Cardiac muscle

d)

Fast‑twitch skeletal muscle

29.

Nervous Tissue — You should be able to identify: What cell type is the basic signaling unit of nervous tissue?

a)

Astrocyte

b)

Neuron

c)

Schwann cell

d)

Microglial cell

30.

Integumentary System — Skin Structure: What are the three main layers of the skin?

a)

Epidermis, dermis, hypodermis

b)

Stratum basale, stratum corneum, dermis

c)

Epidermis, papillary layer, reticular layer

d)

Dermis, endodermis, hypodermis

31.

Integumentary System — Skin Structure: Arrange the epidermal layers in correct order from bottom to top.

a)

Stratum corneum → stratum granulosum → stratum spinosum → stratum basale

b)

Stratum basale → stratum spinosum → stratum granulosum → stratum corneum

c)

Stratum spinosum → stratum basale → stratum granulosum → stratum corneum

d)

Stratum granulosum → stratum basale → stratum spinosum → stratum corneum

32.

Integumentary System — Skin Structure: Which epidermal layer(s) occur only in thick skin?

a)

Stratum basale

b)

Stratum lucidum

c)

Stratum granulosum

d)

Stratum spinosum

33.

Skin Cells & Pigmentation: Which substance primarily determines normal skin color?

a)

Keratin

b)

Melanin

c)

Collagen

d)

Hemoglobin only

34.

Skin Cells & Pigmentation: What is melanin and what is its role in the skin?

a)

A lipid that waterproofs the skin

b)

A pigment that protects against ultraviolet radiation

c)

A carbohydrate that stores energy

d)

A mineral that strengthens bones

35.

Skin Cells & Pigmentation: Which epidermal cells are part of the immune response?

a)

Keratinocytes

b)

Melanocytes

c)

Langerhans (dendritic) cells

d)

Merkel cells

36.

Skin Cells & Pigmentation: Which protein is found in skin, hair, and nails?

a)

Elastin

b)

Keratin

c)

Collagen type II

d)

Actin

37.

Burns: Which description best matches a first‑degree burn?

a)

Only epidermis damaged; redness and pain

b)

Epidermis and part of dermis damaged; blisters

c)

Full thickness burn through epidermis and dermis; often painless at site

d)

Damage extends into muscle and bone

38.

Burns: Which description best matches a second‑degree burn?

a)

Only epidermis damaged; redness and pain

b)

Epidermis and part of dermis damaged; blisters

c)

Full thickness burn through epidermis and dermis; charred, dry

d)

No tissue damage; temporary erythema

39.

Burns: Which description best matches a third‑degree burn?

a)

Only epidermis damaged; redness and pain

b)

Epidermis and part of dermis damaged; blisters

c)

Full thickness burn through epidermis and dermis; often requires grafting

d)

Sunburn that peels

40.

Burns: How does burn depth affect severity?

a)

Deeper burns damage fewer structures and are less severe

b)

Deeper burns increase fluid loss, infection risk, and functional loss

c)

Depth has no effect; only total body surface area matters

d)

Superficial burns are always more severe than deep burns

41.

Burns: Why are third‑degree burns often fatal without prompt treatment?

a)

They cause nerve hyperactivity leading to seizures

b)

They lead to massive fluid loss and infection risk

c)

They directly stop heart function

d)

They always cause airway obstruction

42.

Hair & Nails: Why do haircuts and nail trimming not cause pain?

a)

Hair and nails lack blood vessels and are composed of dead, keratinized cells

b)

Hair and nails are anesthetized by sebum

c)

Pain receptors adapt quickly in hair and nails

d)

Hair and nails are insulated by melanin

43.

Hair & Nails: Why do fingernails and toenails appear pink even though the nail plate is transparent?

a)

Reflection from the stratum corneum

b)

Pigment in the nail matrix

c)

Blood in the underlying vascular nail bed

d)

Light scattering by keratin fibers

44.

Skin Diagrams: When identifying structures on a skin diagram, which option correctly pairs a structure with its description?

a)

Sebaceous gland

1.

Secretes sebum into hair follicles

b)

Hair follicle

2.

Tubular invagination that produces hair

c)

Epidermis

3.

Keratinized stratified epithelial outer layer

d)

Sweat (eccrine) gland

4.

Coiled tubular gland for thermoregulatory sweat

45.

Nervous System — Neurons & Neuroglia: Which parts of a neuron primarily receive input and conduct impulses toward the cell body?

a)

Axon hillock

b)

Dendrites

c)

Axon terminals

d)

Nodes of Ranvier

46.

Nervous System — Neurons & Neuroglia: Which neuron type carries information from receptors to the CNS?

a)

Motor (efferent) neuron

b)

Interneuron

c)

Sensory (afferent) neuron

d)

Purkinje neuron

47.

Nervous System — Neurons & Neuroglia: What is a primary function of neuroglial cells?

a)

Generate action potentials

b)

Provide support, insulation, and metabolic aid to neurons

c)

Store neurotransmitters in muscle cells

d)

Convert glucose directly to action potentials

48.

Action Potentials: Which statement best defines an action potential?

a)

A local, graded change in membrane potential proportional to stimulus strength

b)

A brief, all‑or‑none reversal of membrane potential that propagates along an axon

c)

A chemical change limited to the synaptic cleft

d)

A permanent depolarization of the neuronal membrane

49.

Action Potentials: On a standard action potential graph, which phase immediately follows depolarization?

a)

Hyperpolarization

b)

Repolarization

c)

Resting potential

d)

Threshold

50.

Action Potentials: Which ions are primarily responsible for the rising (depolarization) phase of a neuronal action potential?

a)

K+ efflux

b)

Na+ influx

c)

Cl− influx

d)

Ca2+ influx

51.

Action Potentials: Which statement correctly describes the all‑or‑none principle?

a)

Action potentials vary in amplitude depending on stimulus strength

b)

If threshold is reached, an action potential of fixed amplitude occurs

c)

Larger stimuli create slower action potentials

d)

Subthreshold stimuli create small action potentials

52.

Action Potentials: What is the refractory period?

a)

The time when the neuron is more excitable than normal

b)

The interval during and after an action potential when another impulse is difficult or impossible

c)

The resting interval between synaptic transmissions

d)

The time required for neurotransmitter synthesis

53.

Central & Peripheral Nervous Systems: Which choice correctly distinguishes the CNS from the PNS?

a)

CNS includes brain and spinal cord; PNS includes cranial and spinal nerves

b)

CNS includes somatic and autonomic divisions; PNS includes brain only

c)

CNS includes sensory receptors; PNS includes interneurons only

d)

CNS includes sympathetic division; PNS includes parasympathetic division

54.

Central & Peripheral Nervous Systems: Which components belong to the PNS?

a)

Brain and spinal cord

b)

Cranial nerves and spinal nerves

c)

Cerebrum and cerebellum

d)

Thalamus and hypothalamus

55.

Central & Peripheral Nervous Systems: Which statement best describes the difference between the somatic and autonomic nervous systems?

a)

Somatic controls voluntary skeletal muscle; autonomic regulates involuntary smooth muscle, cardiac muscle, and glands

b)

Somatic controls involuntary organs; autonomic controls voluntary movement

c)

Somatic operates only during sleep; autonomic only during wakefulness

d)

Somatic senses pain; autonomic senses temperature

56.

Central & Peripheral Nervous Systems: Which response is characteristic of the sympathetic division compared to the parasympathetic division?

a)

Decreases heart rate and constricts pupils

b)

Increases heart rate and dilates pupils

c)

Stimulates digestive activity strongly

d)

Promotes lacrimation and salivation

57.

Brain Structure & Function: Which lobe of the brain is primarily associated with visual processing?

a)

Frontal lobe

b)

Parietal lobe

c)

Temporal lobe

d)

Occipital lobe

58.

Brain Structure & Function: Which set lists the four lobes of the cerebrum?

a)

Frontal, parietal, temporal, occipital

b)

Frontal, parietal, insular, limbic

c)

Cerebrum, cerebellum, brain stem, spinal cord

d)

Thalamus, hypothalamus, midbrain, pons

59.

Brain Structure & Function: Which statement correctly pairs a major structure with a primary function?

a)

Cerebrum

1.

Higher cognition and voluntary movement planning

b)

Cerebellum

2.

Coordination, balance, and motor learning

c)

Brain stem

3.

Autonomic functions and basic cranial nerve reflexes

d)

Spinal cord

4.

Conduction pathway for ascending and descending tracts

60.

Brain Structure & Function: What is a primary function of the cerebellum?

a)

Language comprehension

b)

Homeostatic regulation of thirst

c)

Coordination of movements and balance

d)

Long‑term memory consolidation

61.

Brain Structure & Function: Which brain region set is most involved in breathing, balance, sleep, and hormone regulation?

a)

Frontal lobe, hippocampus, amygdala, putamen

b)

Medulla and pons; cerebellum; hypothalamus

c)

Occipital cortex; caudate nucleus; pineal gland

d)

Thalamus; corpus callosum; basal ganglia

62.

Reflexes: Which statement best defines a reflex?

a)

A voluntary response requiring cortical planning

b)

An automatic, rapid response to a stimulus mediated by a neural pathway

c)

A conscious motor program executed by the cerebrum

d)

A behavior learned through repeated practice only

63.

Reflexes: Which list correctly identifies the five parts of a somatic reflex arc?

a)

Receptor, sensory neuron, integration center, motor neuron, effector

b)

Stimulus, brain, spinal cord, muscle, response

c)

Receptor, interneuron, cerebrum, motor neuron, effector

d)

Sensory neuron, thalamus, motor neuron, cerebellum, effector

64.

Reflexes: In a simple patellar reflex, which option correctly identifies the stimulus and the response?

a)

Stimulus: visual cue; Response: quadriceps contraction

b)

Stimulus: stretch of the patellar tendon; Response: knee extension

c)

Stimulus: heat on the skin; Response: withdrawal of the foot

d)

Stimulus: sound; Response: finger flexion

65.

Reflexes: Is the brain directly involved in generating a simple spinal reflex?

a)

Yes; the motor cortex initiates it

b)

No; integration occurs within the spinal cord

c)

Yes; the cerebellum triggers it

d)

Only during sleep

66.

Reflexes: If a patient shows loss of the Achilles tendon reflex, which part of the reflex arc is most likely damaged?

a)

Effector (gastrocnemius/soleus) muscle only

b)

Motor neuron supplying the calf muscles

c)

Visual cortex

d)

Parietal lobe

67.

Identify the basic parts of a homeostatic feedback mechanism.