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Exam 2.4.2 ResMeth and BasNut

Total questions: 150

Worksheet time: 1hrs 15mins

Name
Class
Date
1.

Which monosaccharide is commonly referred to as blood sugar and serves as a major energy source for cells?

a)

Galactose, less sweet milk sugar component

b)

Fructose, sweetest natural sugar in fruits

c)

Glucose, primary cellular energy source

d)

Sucrose, common table sugar from beets

2.

Which pairing correctly identifies the components of a disaccharide?

a)

Lactose: glucose plus galactose

b)

Lactose: fructose plus glucose

c)

Sucrose: glucose plus galactose

d)

Maltose: fructose plus fructose

3.

Which statement best distinguishes simple from complex carbohydrates?

a)

Simple: indigestible; Complex: fully digestible

b)

Simple: slow energy release; Complex: rapid release

c)

Simple: single or double units; Complex: many units

d)

Simple: only plant sources; Complex: only animal

4.

Which description accurately characterizes soluble fiber?

a)

Main storage of glucose in plant tubers and grains

b)

Stored as glycogen in liver and muscle tissues

c)

Forms gels, slows absorption, lowers cholesterol

d)

Does not dissolve, speeds transit, prevents constipation

5.

Which function of carbohydrates is directly linked to providing 4 kcal per gram to fuel brain and red blood cells?

a)

Primary energy source

b)

Glycogen storage

c)

Gastrointestinal health

d)

Fat metabolism support

6.

Insufficient carbohydrate intake increases ketone formation. Which function addresses this outcome?

a)

Fat metabolism: ensures complete oxidation of fat

b)

Protein sparing: reduces nitrogen losses

c)

Soluble fiber: lowers postprandial glucose

d)

Glycogen storage: maintains hepatic reserves

7.

Which statement about glycogen is accurate for human physiology?

a)

Glycogen is the structural fiber in plant cell walls

b)

Glycogen stores glucose in liver and muscles

c)

Glycogen dissolves to form viscous intestinal gels

d)

Glycogen equals sucrose from sugarcane sources

8.

Which enzyme initiates starch digestion in the mouth by producing maltose?

a)

Pancreatic amylase in saliva

b)

Salivary amylase in saliva

c)

Brush-border lactase enzyme

d)

Gastric pepsin in acid

9.

In the stomach, what happens to salivary amylase during carbohydrate digestion?

a)

It converts glucose to glycogen

b)

It is inactivated by acid

c)

It is activated by low pH

d)

It binds fiber fragments

10.

Which intestinal enzymes split disaccharides into monosaccharides for absorption?

a)

Maltase, sucrase, lactase

b)

Aldolase, hexokinase, PFK

c)

Glucagon, insulin, amylin

d)

Trypsin, pepsin, lipase

11.

How are glucose and galactose transported from the intestinal lumen into enterocytes?

a)

Endocytosis of sugars

b)

Facilitated diffusion entry

c)

Active transport uptake

d)

Passive diffusion only

12.

After absorption, where are fructose and galactose converted to glucose?

a)

Skeletal muscle cells

b)

Pancreatic acinar tissue

c)

Hepatic liver via portal

d)

Renal cortex nephrons

13.

Which statement best describes glycogen storage in the body?

a)

Liver stores two-thirds bulk

b)

Muscles store two-thirds bulk

c)

Brain stores half of it

d)

Adipose stores most glycogen

14.

Inside cells, glucose breakdown primarily yields which energy molecule?

a)

Creatine for muscle fibers

b)

NADPH for digestion

c)

GTP for protein folds

d)

ATP for cellular work

15.

What is gluconeogenesis and when does it increase?

a)

Making fat from excess sugar

b)

Making ketones during fasting

c)

Making glucose from protein

d)

Making glycogen from starch

16.

Why is heavy reliance on gluconeogenesis considered undesirable?

a)

It blocks intestinal absorption

b)

It uses essential body protein

c)

It depletes body water quickly

d)

It suppresses pancreatic amylase

17.

What daily carbohydrate intake helps prevent ketosis and spare protein?

a)

10–20 grams intake

b)

25–40 grams intake

c)

120–180 grams intake

d)

50–100 grams intake

18.

When energy needs are met and glycogen stores are full, excess glucose is converted into what?

a)

Fatty acids in adipose

b)

Amino acids in plasma

c)

Lactate in muscles

d)

Ketone bodies in liver

19.

Which bond links amino acids together in a polypeptide chain?

a)

Ionic bond between charged residues

b)

Disulfide bond between cysteine thiols

c)

Peptide bond between carboxyl and amino groups

d)

Hydrogen bond between side chains

20.

Which statement best describes primary protein structure?

a)

Association of multiple polypeptide subunits

b)

Linear sequence of amino acids in a chain

c)

Stabilization by disulfide crosslinks

d)

Spatial arrangement of helices and sheets

21.

What defines a nonessential amino acid in human nutrition?

a)

Must be supplied by the diet

b)

Can be synthesized by the body

c)

Stored in adipose tissue

d)

Required only during illness

22.

Which is classified as an essential amino acid?

a)

Leucine (Leu)

b)

Alanine (Ala)

c)

Aspartic acid (Asp)

d)

Glycine (Gly)

23.

Which amino acid is conditionally essential during illness or metabolic stress?

a)

Glutamate (Glu)

b)

Arginine (Arg)

c)

Phenylalanine (Phe)

d)

Proline (Pro)

24.

Which process occurs in the stomach during protein digestion?

a)

Absorption of intact polypeptides

b)

Denaturation by HCl and hydrolysis by pepsin

c)

Formation of disulfide bridges

d)

Mechanical crushing without chemical change

25.

Which enzyme class in the small intestine breaks peptides into tri-, dipeptides, and amino acids?

a)

Lipoprotein lipases

b)

Salivary amylases

c)

Pancreatic and intestinal peptidases

d)

Pepsin in gastric lumen

26.

At the quaternary level, proteins are characterized by which feature?

a)

Assembly of multiple polypeptide subunits

b)

Three-dimensional folding of a single chain

c)

Covalent modification of side chains

d)

Local backbone hydrogen bonding patterns

27.

Which abbreviation correctly matches its amino acid?

a)

Lys (M) for Lysine

b)

Ile (L) for Isoleucine

c)

His (H) for Histidine

d)

Leu (I) for Leucine

28.

Which amino acid is nonessential in human metabolism?

a)

Valine (Val)

b)

Tryptophan (Trp)

c)

Threonine (Thr)

d)

Serine (Ser)

29.

Which statement about peptide bonds is accurate?

a)

Rotate freely around the C–N bond

b)

Formed by condensation releasing water

c)

Break by hydrogenation adding oxygen

d)

Create side-chain branching points

30.

Which is an essential branched-chain amino acid?

a)

Glutamine

b)

Leucine

c)

Alanine

d)

Aspartate

31.

Which amino acid commonly forms disulfide bonds stabilizing tertiary structure?

a)

Cysteine

b)

Glycine

c)

Proline

d)

Asparagine

32.

Where does initial mechanical processing of protein occur without significant chemical digestion?

a)

Mouth

b)

Stomach

c)

Small intestine

d)

Large intestine

33.

Which pair lists two essential amino acids correctly?

a)

Alanine and Glycine

b)

Methionine and Phenylalanine

c)

Aspartate and Glutamate

d)

Proline and Serine

34.

Which best describes secondary protein structure elements?

a)

Linear order of residues determined by mRNA

b)

Subunit interactions forming multimeric complexes

c)

Covalent crosslinks created during folding

d)

Alpha helices and beta sheets stabilized by hydrogen bonds

35.

During gastric digestion, pepsin primarily performs which action on proteins?

a)

Cleaves peptide bonds generating smaller peptides

b)

Transaminates amino acids for gluconeogenesis

c)

Phosphorylates serine residues

d)

Reduces disulfide bridges to thiols

36.

Which amino acid classification is correct for Glycine (Gly)?

a)

Essential indispensable nutrient

b)

Non-nutritive peptide derivative

c)

Nonessential synthesized endogenously

d)

Conditionally essential in all adults

37.

Which outcome is expected from pancreatic trypsin and chymotrypsin activity?

a)

Neutralization of gastric acid

b)

Formation of intact polypeptide chains

c)

Hydrolysis of peptides into smaller fragments

d)

Complete absorption of whole proteins

38.

Which enzyme initiates protein digestion in the stomach by cleaving peptide bonds?

a)

Carboxypeptidase from pancreas

b)

Trypsin from pancreatic juice

c)

Pepsin activated by gastric acid

d)

Chymotrypsin in small intestine

39.

Which statement best describes the role of pancreatic proteases during intestinal protein digestion?

a)

They transport amino acids into portal vein

b)

They convert amino acids into urea

c)

They complete hydrolysis into amino acids

d)

They denature proteins by low pH

40.

Which function of proteins directly involves catalyzing chemical reactions in the body?

a)

Hormones signaling target cells

b)

Antibodies defending against pathogens

c)

Structural materials for connective tissue

d)

Enzymes facilitating metabolism

41.

A person recovering from illness with adequate protein intake is most likely in which nitrogen status?

a)

Negative nitrogen balance

b)

Positive nitrogen balance

c)

Neutral nitrogen equilibrium

d)

Erratic nitrogen turnover

42.

Which scenario most likely produces negative nitrogen balance?

a)

Growth with high protein meals

b)

Pregnancy with sufficient calories

c)

Starvation with severe stress

d)

Recovery with supplemental amino acids

43.

What is removed during deamination when amino acids are not used for protein synthesis?

a)

Hydrogen atoms forming water

b)

Side chains forming ketones

c)

Amino group producing ammonia

d)

Carboxyl group forming CO2

44.

In the liver, ammonia generated from deamination is converted into which compound for safe excretion?

a)

Ketone bodies via beta-oxidation

b)

Glucose by glycogenesis

c)

Urea through the urea cycle

d)

Lactate via Cori pathway

45.

The carbon skeleton (keto acid) from deaminated amino acids can be channeled primarily into which pathway to produce ATP?

a)

Beta-oxidation in adipocytes

b)

Electron transport to yield NADPH

c)

Citric acid cycle after transamination

d)

Glycolysis without oxygen supply

46.

During transcription in protein synthesis, which event occurs?

a)

DNA codes are copied into mRNA

b)

Ribosomes assemble polypeptide chains

c)

Amino acids are activated by tRNA

d)

Peptide bonds are cleaved by pepsin

47.

Which statement best distinguishes translation from transcription in protein synthesis?

a)

Translation assembles amino acids into proteins

b)

Translation copies DNA into mRNA

c)

Translation edits nucleotides in the nucleus

d)

Translation degrades mRNA after synthesis

48.

Which process increases urea production and renal workload when protein intake is excessive?

a)

Hydrogenation of carbon skeletons

b)

Transamination of essential amino acids

c)

Condensation of peptide bonds

d)

Deamination of surplus amino acids

49.

When carbohydrate intake is insufficient, certain amino acids are converted to glucose to maintain blood levels. What is this process called?

a)

Glycogenolysis in adipose

b)

Gluconeogenesis in the liver

c)

Glycolysis in mitochondria

d)

Glycogenesis in skeletal muscle

50.

Which statement best describes triglyceride formation during a condensation reaction?

a)

Glycerol and phosphates form esters without water loss

b)

Three glycerol units bind one fatty acid releasing water

c)

Glycerol binds three fatty acids releasing three waters

d)

Glycerol binds two fatty acids releasing one water

51.

Which feature distinguishes phospholipids from triglycerides in structure and function?

a)

Phospholipids are fully hydrophobic molecules

b)

A glycerol backbone is absent in phospholipids

c)

One fatty acid replaced by a phosphate group

d)

Two phosphate groups replace two fatty acids

52.

Which role is correctly matched to sterols in the body?

a)

Precursor for bile acids and steroid hormones

b)

Primary energy storage in adipocytes

c)

Carrier of lipids in the lymphatic system

d)

Main emulsifier for intestinal fat digestion

53.

Which property defines saturated fatty acids at the molecular level?

a)

Contain one or more double bonds

b)

Contain no double bonds between carbons

c)

Contain a triple bond in the chain

d)

Contain conjugated double bonds only

54.

At room temperature, which characteristic commonly applies to saturated fats?

a)

Liquid and decrease triglycerides

b)

Solid and increase HDL cholesterol

c)

Solid and increase LDL cholesterol

d)

Liquid and lower LDL cholesterol

55.

Which statement correctly contrasts MUFA and PUFA?

a)

MUFA have one double bond; PUFA have two or more

b)

MUFA are trans; PUFA are always cis

c)

MUFA have no double bonds; PUFA have one

d)

MUFA have two double bonds; PUFA have none

56.

Which pair lists the essential fatty acids the body cannot synthesize?

a)

Linoleic and alpha‑linolenic acids

b)

Elaidic and conjugated linoleic acids

c)

Oleic acid and stearic acid

d)

Palmitic and arachidic acids

57.

Which statement about trans fatty acids formed by hydrogenation is accurate?

a)

Decrease both LDL and HDL cholesterol

b)

Increase LDL and lower HDL cholesterol

c)

Lower LDL and raise HDL cholesterol

d)

Do not affect cardiovascular risk

58.

Which event occurs during absorption of dietary lipids into the body?

a)

Chylomicrons enter directly into portal blood

b)

Cholesterol converts to glucose in enterocytes

c)

Triglycerides stay unmodified in cells

d)

Micelles deliver lipids to enterocytes

59.

After intestinal absorption of long-chain fatty acids, what particle transports them initially through the lymphatic system before reaching the bloodstream?

a)

Very-low-density lipoproteins

b)

Chylomicrons formed in enterocytes

c)

Albumin-bound free fatty acids

d)

High-density lipoproteins

60.

Which enzyme mobilizes stored triglycerides in adipose tissue during energy demand by hydrolyzing them into fatty acids and glycerol?

a)

Lipoprotein lipase on capillaries

b)

Hormone-sensitive lipase in adipocytes

c)

Pancreatic lipase in duodenum

d)

Acetyl-CoA carboxylase in liver

61.

During fasting, which statement best describes how the body uses fat for energy?

a)

Glycerol converts fully to ketone bodies

b)

Triglycerides are first converted to glycogen then oxidized

c)

Fatty acids undergo beta-oxidation to generate ATP

d)

Fatty acids can directly fuel red blood cells

62.

Prolonged glucose deprivation leads the liver to produce ketone bodies. What is the primary rationale for this adaptation?

a)

To replace glycogen as the only fuel for muscles

b)

To increase bile salt synthesis for fat absorption

c)

To prevent glycerol from entering gluconeogenesis

d)

To supply an alternative energy substrate for the brain

63.

Which component of triglycerides can contribute to blood glucose maintenance during fasting via gluconeogenesis?

a)

Ketone bodies circulating during starvation

b)

Acetyl-CoA units entering the TCA cycle

c)

The glycerol backbone released from lipolysis

d)

The fatty acid chains after beta-oxidation

64.

Which deficiency is classically associated with niacin and presents with dermatitis, diarrhea, dementia, and death?

a)

Pellagra with the four D’s

b)

Pernicious anemia with pallor

c)

Beriberi with neuropathy and edema

d)

Scurvy with bleeding gums

65.

A diet very low in niacin and tryptophan, such as heavy reliance on untreated corn, most likely leads to which condition?

a)

Pernicious anemia due to B12 lack

b)

Scurvy due to vitamin C lack

c)

Rickets due to vitamin D lack

d)

Pellagra due to niacin deficiency

66.

High supplemental niacin can cause which adverse effect at doses above typical intakes?

a)

Bone pain and fractures

b)

Hair loss and brittle nails

c)

Night blindness and dry eyes

d)

Niacin flush and liver damage

67.

Which process is most directly supported by vitamin B6 coenzymes in human metabolism?

a)

DNA strand separation

b)

Transamination and decarboxylation

c)

Phototransduction in retina

d)

Beta-oxidation of fatty acids

68.

Deficiency of vitamin B6 is most commonly linked to which neurologic or hematologic issue?

a)

Microcytic anemia with dermatitis

b)

Macrocytic anemia with glossitis

c)

Aplastic anemia with pancytopenia

d)

Hemolytic anemia with jaundice

69.

Which is a key function of pantothenic acid (vitamin B5) in energy metabolism?

a)

Chelates iron in the intestine

b)

Acts as an antioxidant scavenger

c)

Transfers methyl groups to DNA

d)

Forms acetyl-CoA for the Krebs cycle

70.

Biotin deficiency is rare but classically occurs with chronic consumption of raw egg whites due to which mechanism?

a)

Avidin binding biotin and preventing absorption

b)

Casein blocking intestinal transporters

c)

Oxalates forming insoluble biotin salts

d)

Lectins damaging villi and reducing uptake

71.

Which symptoms are most consistent with biotin deficiency?

a)

Bleeding gums, poor wound healing

b)

Night blindness, keratinization problems

c)

Edema, paresthesia, cardiac failure

d)

Dermatitis, hair loss, neurologic issues

72.

Which B-vitamin works together with B12 in red blood cell formation and homocysteine metabolism?

a)

Pantothenate forming CoA

b)

Biotin assisting carboxylation

c)

Folate supporting DNA synthesis

d)

Niacin aiding NAD synthesis

73.

A pregnant individual deficient in folate faces increased risk for which fetal outcome?

a)

Neural tube defects like spina bifida

b)

Cleft palate and micrognathia

c)

Craniosynostosis and torticollis

d)

Tetralogy of Fallot heart disease

74.

Which hematologic change typifies folate deficiency?

a)

Megaloblastic anemia with large RBCs

b)

Microcytic anemia with low MCV

c)

Hemolytic anemia with high bilirubin

d)

Polycythemia with high hematocrit

75.

Vitamin B12 absorption requires which gastric component to be present?

a)

Intrinsic factor secreted by stomach

b)

Pancreatic proteases for cleavage

c)

Bile salts from the gallbladder

d)

Gastric acid for ionization

76.

Which neurological consequence can result from prolonged vitamin B12 deficiency?

a)

Restless leg syndrome

b)

Irreversible nerve degeneration

c)

Transient visual aura

d)

Intermittent muscle cramps

77.

What is a primary biochemical role of vitamin C relevant to connective tissue?

a)

Urea cycle regulation and ammonia detox

b)

Beta-carotene conversion to retinol

c)

Collagen formation and wound healing

d)

Ceramide synthesis for skin barrier

78.

Which clinical picture best matches scurvy?

a)

Tetany with carpopedal spasm

b)

Photosensitivity and scaly dermatitis

c)

Bone softening and bowed legs

d)

Bleeding gums and pinpoint hemorrhages

79.

Which statement best describes a benefit of vitamin C beyond its role in collagen?

a)

Blocks intrinsic factor binding

b)

Increases bile acid synthesis

c)

Activates vitamin D receptors

d)

Aids non-heme iron absorption

80.

Heavy vitamin C supplementation can lead to which adverse outcomes?

a)

Bronchospasm and wheezing

b)

Hepatic steatosis and pruritus

c)

Hyperkalemia and arrhythmias

d)

Diarrhea and false test results

81.

Which pairing correctly matches vitamin with common food sources noted for that nutrient?

a)

Vitamin C—citrus and bell peppers

b)

Vitamin B12—leafy greens mainly

c)

Biotin—raw egg whites primarily

d)

Niacin—only legumes and nuts

82.

Which form of vitamin A is directly involved in gene expression regulation?

a)

Retinol stores in hepatic stellate cells

b)

Retinoic acid regulates gene expression

c)

Retinal forms rhodopsin in retina

d)

Beta-carotene converts to retinol

83.

Vitamin A deficiency early sign most closely linked to visual function is:

a)

Night blindness from rhodopsin deficit

b)

Photophobia due to corneal edema

c)

Peripheral vision loss from glaucoma

d)

Color blindness from cone damage

84.

Which statement best describes vitamin D activation?

a)

Forms active hormone during sunlight storage

b)

Becomes active when bound to albumin

c)

Activated in gut by pancreatic enzymes

d)

Converted to calcitriol by liver then kidneys

85.

Primary physiological role of vitamin D is to:

a)

Regulate calcium and phosphorus absorption

b)

Increase rhodopsin regeneration rate

c)

Serve as cofactor for prothrombin

d)

Stabilize polyunsaturated fatty acids

86.

A child presenting with bowed legs most likely has deficiency of:

a)

Vitamin K causing hemorrhage

b)

Vitamin D causing rickets

c)

Vitamin A causing xerophthalmia

d)

Vitamin E causing anemia

87.

Which is a classic antioxidant role of vitamin E?

a)

Protect cell membranes from oxidation

b)

Enhance rhodopsin light sensitivity

c)

Stimulate calcitriol receptor binding

d)

Increase prothrombin synthesis rate

88.

Excess vitamin D intake is most associated with:

a)

Hemorrhaging due to impaired clotting

b)

Hypercalcemia and soft tissue calcification

c)

Neuromuscular weakness in infants

d)

Liver fibrosis and birth defects

89.

Which best matches vitamin K’s primary function?

a)

Vision via rhodopsin regeneration

b)

Blood clotting via prothrombin synthesis

c)

Calcium absorption in intestinal mucosa

d)

Antioxidant protection of membranes

90.

Newborns are at risk of vitamin K deficiency mainly because:

a)

High oxidative stress depletes tocopherols

b)

Low liver stores of retinoids

c)

Low sunlight reduces cholecalciferol

d)

Low gut bacteria reduces synthesis

91.

Which source pair correctly matches the vitamin predominantly obtained?

a)

Leafy greens provide vitamin K

b)

Wheat germ provides vitamin D

c)

Sunlight provides vitamin E mostly

d)

Fatty fish provide vitamin A only

92.

Recommended dietary allowance noted for α-tocopherol (vitamin E) is closest to:

a)

900 μg RAE per day for men

b)

120 μg per day for men

c)

600 IU per day for adults

d)

15 mg per day for adults

93.

Which deficiency sign is linked with vitamin E?

a)

Night blindness due to rhodopsin loss

b)

Rickets with bone deformities

c)

Hemolytic anemia due to RBC destruction

d)

Prolonged clotting time with bleeding

94.

Which toxicity concern is correctly paired with the vitamin?

a)

Vitamin E invariably causes hemorrhage

b)

Vitamin K commonly causes severe toxicity

c)

Vitamin A may cause birth defects

d)

Vitamin D never leads to kidney stones

95.

Which statement about vitamin D forms is accurate?

a)

D2 synthesized in human skin

b)

D2 is active without conversion

c)

D3 from sunlight and animal foods

d)

D3 exclusive to plant sources

96.

Which nutrient interaction is noted for vitamin E at high intakes?

a)

Competes with calcium absorption

b)

Inhibits calcitriol synthesis pathway

c)

Enhances retinal pigment formation

d)

May interfere with vitamin K clotting

97.

Which role of calcium most directly explains its effect on bone density?

a)

Forming hydroxyapatite structural matrix

b)

Modulating blood clotting cascade

c)

Regulating hormone secretion signals

d)

Facilitating nerve impulse transmission

98.

A patient with low-ionized calcium presents with tetany. Which mechanism best accounts for this symptom?

a)

Reduced ATP in skeletal muscle fibers

b)

Increased sodium retention in kidneys

c)

Instability in neuromuscular excitability thresholds

d)

Excess chloride causing gastric hyperacidity

99.

Which dietary pattern most appropriately supports the adult RDA for calcium?

a)

Milk, yogurt, leafy greens, fortified tofu

b)

Meat, poultry, eggs, cola beverages

c)

Seafood, chocolate, whole grains

d)

Table salt, soy sauce, cured meats

100.

Phosphorus contributes to energy metabolism primarily by its presence in which compound?

a)

Choline phospholipid methyl donor

b)

ATP phosphate groups for energy transfer

c)

Hydrochloric acid gastric secretion

d)

Myoglobin oxygen storage protein

101.

Excess phosphorus intake is most likely to lead to which outcome?

a)

Hypokalemia with irregular heartbeat

b)

Hypernatremia with muscle cramps

c)

Alkalosis from chloride deficiency

d)

Calcification of soft tissues due to imbalance

102.

Magnesium’s role that most closely links it to ATP metabolism is:

a)

Cofactor in 300+ enzymatic reactions

b)

Primary extracellular cation function

c)

Formation of disulfide bonds in proteins

d)

Component of hemoglobin oxygen transport

103.

Which scenario most plausibly causes magnesium deficiency?

a)

High table salt intake increasing sodium

b)

Chronic alcoholism or diuretic use

c)

Excess bananas raising potassium

d)

Low chloride reducing acid-base balance

104.

A man taking high-dose magnesium supplements develops diarrhea and alkalosis. Which intake level context aligns with this risk?

a)

Above UL of 2,300 mg chloride per day

b)

Exceeding AI of 4,700 mg potassium per day

c)

Below AI of 2,300 mg sodium per day

d)

Near RDA of 400 mg magnesium per day

105.

Sodium’s primary physiological identity is:

a)

Major intracellular anion in cytosol

b)

Major extracellular anion in blood

c)

Major extracellular cation in plasma

d)

Major intracellular cation in cells

106.

Which outcome is most characteristic of sodium toxicity from high salt intake?

a)

Protein structure instability from sulfur

b)

Cardiac arrest due to hyperkalemia

c)

Metabolic acidosis with chloride excess

d)

Edema and increased cardiovascular risk

107.

A patient with hypokalemia is most likely to present with:

a)

Nausea and confusion from hypernatremia

b)

Muscle weakness and irregular heartbeat

c)

Diarrhea and metabolic alkalosis

d)

Tetany and calcified soft tissues

108.

Which condition most directly results from inadequate iodine intake during development?

a)

Keshan disease with cardiomyopathy

b)

Fluorosis with mottled teeth and bone pain

c)

Wilson’s disease with copper accumulation

d)

Goiter with impaired thyroid hormone production

109.

Zinc serves which primary biochemical role relevant to genetic material?

a)

Cofactor for DNA and RNA synthesis

b)

Carrier for thyroid hormone transport

c)

Structural component of fluorapatite

d)

Direct antioxidant substituting vitamin E

110.

Fluoride helps prevent dental caries primarily by which mechanism?

a)

Blocking copper absorption in intestines

b)

Enhancing insulin receptor signaling

c)

Increasing salivary iodine concentration

d)

Forming fluorapatite that strengthens enamel

111.

Which pair correctly matches a trace mineral with a notable deficiency outcome?

a)

Zinc—loss of taste and delayed maturity

b)

Fluoride—Wilson’s disease with copper storage

c)

Iodine—gout-like symptoms and joint pain

d)

Chromium—Keshan cardiomyopathy in children

112.

A patient with brittle hair and nails, garlic breath odor, and fatigue is most likely experiencing toxicity from which mineral?

a)

Manganese from leafy vegetables

b)

Copper from shellfish overuse

c)

Fluoride from fluoridated water

d)

Selenium from excessive intake

113.

Which scenario best illustrates strategic use of diet to reduce iron-deficiency anemia risk in a vegetarian?

a)

Combine legumes with vitamin C–rich foods

b)

Rely on tea to aid iron absorption

c)

Avoid fortified cereals in daily meals

d)

Choose only whole grains without fruits

114.

Chromium’s key physiological contribution is most closely related to which process?

a)

Activating thyroid hormones from iodide

b)

Enhancing insulin action and glucose use

c)

Forming collagen in connective tissues

d)

Preventing oxidative damage with vitamin E

115.

Which clinical sign best differentiates fluorosis from simple dental decay?

a)

Enamel fully intact with mild sensitivity

b)

Painful cavities without enamel changes

c)

Smooth enamel with white spots only

d)

Mottled enamel with skeletal effects

116.

Which toxicity profile most aligns with excessive copper accumulation?

a)

Neurological disorder from inhaled dust exposure

b)

Gout-like symptoms involving uric acid

c)

Garlic breath odor and brittle nails

d)

Liver damage with vomiting and Wilson’s disease

117.

Which combination of sources best supports adequate iodine intake for most adults?

a)

Leafy vegetables with tea beverages

b)

Iodized salt with seafood and seaweed

c)

Organ meats with seeds and shellfish

d)

Whole grains with nuts and broccoli

118.

Which principle of diet planning is met when a diet supplies all essential nutrients, fiber, and energy needed to maintain health?

a)

Adequacy of essential needs

b)

Moderation of high-fat foods

c)

Variety of dietary choices

d)

Balance across food groups

119.

A diet that balances calcium from dairy with iron from meat primarily exemplifies which principle?

a)

Nutrient balance proportions

b)

Energy control balance

c)

Variety across meals

d)

Moderation in sweets

120.

Which statement best defines energy density?

a)

Calories per gram

b)

Minerals per cup

c)

Vitamins per serving

d)

Fiber per portion

121.

Choosing fruits over pastries to reduce calories while getting vitamins and fiber is an example of which concept?

a)

Food group rotation

b)

Nutrient density focus

c)

Energy density choice

d)

Portion size control

122.

Moderation in diet primarily means what?

a)

Maximizing protein at meals

b)

Eating sweets every day

c)

Occasional treats within health

d)

Avoiding all fats completely

123.

Rotating between chicken, fish, and tofu to diversify nutrient profiles reflects which principle?

a)

Adequacy of intake

b)

Variety across foods

c)

Moderation in sugar

d)

Energy control targets

124.

Which food group is the major source of carbohydrates, fiber, and B vitamins with a typical recommendation of 6–11 servings per day?

a)

Fruit group

b)

Fats, oils, sweets

c)

Grains group

d)

Milk and dairy

125.

The Milk and Dairy Group primarily provides which nutrients?

a)

Vitamin C and folate

b)

Fiber and B vitamins

c)

Iron and zinc

d)

Calcium and protein

126.

On a Nutrition Facts label, Percent Daily Value (%DV) is typically based on what reference intake?

a)

1,200 kcal diet

b)

1,800 kcal diet

c)

2,000 kcal diet

d)

2,500 kcal diet

127.

If a snack shows 10% DV for calcium, what does one serving provide?

a)

Ten percent of daily calcium

b)

Ten milligrams of calcium

c)

Ten percent of total calories

d)

Ten grams of calcium

128.

Which anthropometric measure primarily estimates muscle mass and fat stores in malnourished adults and children?

a)

Head circumference tracking

b)

Mid-upper arm circumference

c)

Waist circumference measurement

d)

Triceps skinfold thickness

129.

A patient has BMI 27.2 kg/m². Which classification fits this BMI?

a)

Underweight classification

b)

Normal weight status

c)

Obese category

d)

Overweight classification

130.

Unintentional weight loss greater than 5% in one month most likely indicates which situation?

a)

Stable nutritional status

b)

Improved metabolic efficiency

c)

Possible malnutrition or disease

d)

Normal adaptation to exercise

131.

Which data type involves analyzing blood, urine, or tissue to detect nutrient abnormalities?

a)

Dietary recall logs

b)

Biochemical data analysis

c)

Physical examination notes

d)

Clinical symptom records

132.

Which statement best describes the purpose of a 24-hour dietary recall?

a)

Assess nerve conduction velocity

b)

Record foods eaten in the past day

c)

Measure subscapular fat thickness

d)

Calculate bone mineral density

133.

Which waist circumference threshold signals increased metabolic risk?

a)

>110 cm for men, >90 cm for women

b)

>88 cm for men, >102 cm for women

c)

>102 cm for men, >88 cm for women

d)

>95 cm for men, >85 cm for women

134.

Low serum potassium is most likely associated with which clinical manifestation?

a)

Greater fluid retention

b)

Enhanced nerve conduction

c)

Muscle weakness or arrhythmia

d)

Improved cardiac contractility

135.

During physical examination, which finding may suggest chronic energy deficiency?

a)

Rapid hair growth and weight gain

b)

Weakness, dry skin, weight loss

c)

High bone density on imaging

d)

Glowing skin with edema

136.

Which fat distribution pattern is linked with higher cardiometabolic risk?

a)

Android with abdominal fat

b)

Gynoid with hip–thigh fat

c)

Peripheral limb fat only

d)

Uniform subcutaneous fat

137.

Which BMI range is considered normal and carries minimal health risk?

a)

18.5 to 24.9 kg/m²

b)

Greater than or equal to 30 kg/m²

c)

Less than 18.5 kg/m²

d)

25 to 29.9 kg/m²

138.

Which BMI value most commonly marks the threshold for obesity classification in adults?

a)

BMI of 27 kg/m²

b)

BMI of 25 kg/m²

c)

BMI of 30 kg/m²

d)

BMI of 35 kg/m²

139.

Which factor is a behavioral cause that contributes to obesity risk?

a)

Frequent cold exposure

b)

High altitude residence

c)

Daily water fasting

d)

Sedentary lifestyle habits

140.

What is the most appropriate initial strategy to create a moderate energy deficit for weight loss?

a)

Eliminate entire macronutrient groups

b)

Provide fewer calories than expended

c)

Double protein intake immediately

d)

Skip meals on alternating days

141.

A client has weak immunity and delayed wound healing due to low body weight. Which management step is most suitable?

a)

Begin high-intensity interval training

b)

Adopt intermittent fasting schedule

c)

Restrict dietary fat to minimum

d)

Increase nutrient-dense calorie intake

142.

Which health risk is most strongly associated with excess adiposity?

a)

Kidney stone formation

b)

Benign skin nevi growth

c)

Seasonal allergic rhinitis

d)

Type 2 diabetes mellitus

143.

For long-term weight management, which approach best supports maintenance after reaching a healthy weight?

a)

Balanced eating with self-monitoring

b)

Eliminate social support networks

c)

Cycle crash diets every quarter

d)

Stop all physical activity

144.

Using the BMI-based DBW formula DBW (kg) = height (m)² × 22, what is the desirable body weight for an adult 1.70 m tall?

a)

56.1 kilograms

b)

75.4 kilograms

c)

63.6 kilograms

d)

70.0 kilograms

145.

Which formula expresses Body Mass Index (BMI) in metric units?

a)

BMI equals height divided by weight squared

b)

BMI equals weight divided by height squared

c)

BMI equals weight plus height squared

d)

BMI equals weight times height squared

146.

For a non-Asian population, which BMI range is classified as Overweight (at risk)?

a)

Less than 18.5 kg/m²

b)

30.0 to 34.9 kg/m²

c)

25.0 to 29.9 kg/m²

d)

18.5 to 24.9 kg/m²

147.

Using BMI to estimate Desirable Body Weight (DBW), what factor multiplies height squared in meters?

a)

Multiply by 22 to get DBW

b)

Multiply by 30 to get DBW

c)

Multiply by 25 to get DBW

d)

Multiply by 18.5 to get DBW

148.

A person weighs 58 kg and is 1.58 m tall. What is the approximate BMI?

a)

19.80 kg/m²

b)

25.50 kg/m²

c)

23.23 kg/m²

d)

21.00 kg/m²

149.

Which classification corresponds to BMI 35.0–39.9 kg/m²?

a)

Class III Obesity

b)

Normal Weight

c)

Class I Obesity

d)

Class II Obesity

150.

A height of 1.549 m is used to compute DBW via BMI. Which result is closest when multiplying height squared by 22?

a)

About 39.1 kg

b)

About 60.2 kg

c)

About 45.0 kg

d)

About 52.8 kg