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Antipsychotic Drugs Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Antipsychotic drugs are primarily used to treat

a)

Depression

b)

Schizophrenia

c)

Epilepsy

d)

Anxiety disorders

2.

Typical antipsychotics mainly block

a)

Dopamine D2 receptors

b)

Serotonin 5-HT2 receptors

c)

GABA receptors

d)

NMDA receptors

3.

Atypical antipsychotics differ from typical ones by predominant blockade of

a)

D2 receptors only

b)

5-HT2 receptors

c)

Muscarinic receptors

d)

Alpha receptors

4.

Chlorpromazine belongs to which class?

a)

Butyrophenone

b)

Thioxanthene

c)

Phenothiazine

d)

Atypical antipsychotic

5.

Mechanism of action of chlorpromazine is mainly by blocking

a)

Dopamine D2 receptors

b)

Serotonin receptors

c)

GABA receptors

d)

Opioid receptors

6.

Therapeutic use of chlorpromazine includes all EXCEPT

a)

Schizophrenia

b)

Mania

c)

Motion sickness

d)

Parkinson disease

7.

Chlorpromazine produces sedation mainly due to blockade of

a)

Alpha-1 receptors

b)

Muscarinic receptors

c)

Histamine H1 receptors

d)

Dopamine receptors

8.

Major extrapyramidal adverse effect of chlorpromazine is

a)

Tardive dyskinesia

b)

Respiratory depression

c)

Hepatotoxicity

d)

Nephrotoxicity

9.

Endocrine adverse effect of chlorpromazine includes

a)

Gynecomastia

b)

Hyperthyroidism

c)

Adrenal insufficiency

d)

Diabetes insipidus

10.

Autonomic adverse effect of chlorpromazine includes

a)

Hypertension

b)

Bradycardia

c)

Postural hypotension

d)

Constipation relieved

11.

Chlorpromazine can cause photosensitivity due to its effect on

a)

Skin melanin

b)

DNA repair

c)

UV absorption

d)

Immune response

12.

Neuroleptic malignant syndrome is characterized by all EXCEPT

a)

Hyperthermia

b)

Muscle rigidity

c)

Autonomic instability

d)

Eosinophilia

13.

Drug of choice for treating neuroleptic malignant syndrome is

a)

Diazepam

b)

Dantrolene

c)

Haloperidol

d)

Phenytoin

14.

High potency typical antipsychotic is

a)

Chlorpromazine

b)

Thioridazine

c)

Haloperidol

d)

Clozapine

15.

Low potency antipsychotics are associated with more

a)

EPS

b)

Autonomic side effects

c)

Parkinsonism

d)

Tardive dyskinesia

16.

Lignocaine is classified as

a)

General anesthetic

b)

Local anesthetic (amide type)

c)

Local anesthetic (ester type)

d)

Sedative hypnotic

17.

Mechanism of action of lignocaine is by blocking

a)

Calcium channels

b)

Potassium channels

c)

Sodium channels

d)

Chloride channels

18.

Lignocaine is commonly used for all EXCEPT

a)

Local anesthesia

b)

Ventricular arrhythmias

c)

Spinal anesthesia

d)

Status epilepticus

19.

Systemic adverse effect of lignocaine toxicity includes

a)

Bradycardia

b)

CNS excitation and seizures

c)

Hyperthermia

d)

Renal failure

20.

Addition of adrenaline to lignocaine results in all EXCEPT

a)

Prolonged duration

b)

Reduced systemic toxicity

c)

Increased local blood flow

d)

Reduced bleeding